One of the 2 membranecovered spaces between the bones of a baby’s skull. At birth, the skull bones are not yet fully fused, and 2 soft areas can be felt through the scalp. These are the anterior fontanelle, which is diamond-shaped and usually closes up by
age 18 months, and the posterior fontanelle, which is triangular and closes up within the first 2 months. It is normal for the fontanelles to become tense and bulge out when a baby cries. Persistent tension at other times may indicate an abnormality, particularly hydrocephalus (the accumulation of fluid in the skull). A sunken fontanelle may be a sign of dehydration. If a fontanelle is abnormally large, or takes a long time to close, the cause may be a brain abnormality or a disorder, such as rickets, affecting the skull bones. Early closure of the fontanelles results in a deformity called craniosynostosis.
Occasionally, a third fontanelle is present between the other 2; this occurs in Down’s syndrome.
Areas on the head on which bone has not yet formed. The chief of these is the anterior fontanelle, situated on the top of the head between the frontal and two parietal bones. In shape it is four-sided, about 25 mm (1 inch) square at the time of birth, gradually diminishing until it is completely covered by bone, which should happen by the age of 18 months. The pulsations of the brain can be readily felt through it. Delay in its closure is particularly found in cases of RICKETS, as well as in other states of defective development. The fontanelle bulges in raised intracranial pressure from HYDROCEPHALUS and MENINGITIS, and depressed in DEHYDRATION.
n. an opening in the skull of a fetus or young infant due to incomplete *ossification of the cranial bones and the resulting incomplete closure of the *sutures. The anterior fontanelle occurs where the coronal, frontal, and sagittal sutures meet; the posterior fontanelle occurs where the sagittal and lambdoidal sutures meet (see illustration).
An abnormal accumulation of CEREBROSPINAL FLUID, or CSF, within the skull, as a result of one or more of three main causes: (i) excessive CSF production; (ii) defective CSF absorption;
(iii) blockage of the circulation of CSF. Such disturbances in the circulation of the ?uid may be due to congenital reasons (most commonly associated with SPINA BIFIDA), to MENINGITIS, or to a tumour.
Symptoms In children, the chief symptoms observed are the gradual increase in size of the upper part of the head, out of all proportion to the face or the rest of the body. The head is globular, with a wide anterior FONTANELLE and separation of the bones at the sutures. The veins in the scalp are prominent, and there is a ‘crackpot’ note on percussion. The normal infant’s head should not grow more than 2·5 cm (1 inch) in each of the ?rst two months of life, and much more slowly subsequently; growth beyond this rate should arouse suspicions of hydrocephalus, so medical professionals caring for infants use centile charts for this purpose.
The cerebral ventricles are widely distended, and the convolutions of the brain ?attened, while occasionally the ?uid escapes into the cavity of the cranium, which it ?lls, pressing down the brain to the base of the skull. As a consequence of such changes, the functions of the brain are interfered with, and in general the mental condition of the patient is impaired. Untreated, the child is dull and listless, irritable and sometimes suffers from severe mental subnormality. The special senses become affected as the disease advances, especially vision, and sight is often lost, as is also hearing. Towards the end, paralysis is apt to occur.
Treatment Numerous ingenious operations have been devised for the treatment of hydrocephalus. The most satisfactory of these utilise unidirectional valves and shunts (tubes), whereby the cerebrospinal ?uid is bypassed from the brain into the right atrium of the heart or the peritoneal cavity. The shunt may have to be left in position inde?nitely.... hydrocephalus
(osteogenesis) n. the formation of *bone, which takes place in three stages by the action of special cells (osteoblasts). A meshwork of collagen fibres is deposited in connective tissue, followed by the production of a cementing polysaccharide. Finally the cement is impregnated with minute crystals of calcium salts. The osteoblasts become enclosed within the matrix as osteocytes (bone cells). In intracartilaginous (or endochondral) ossification the bone replaces cartilage. This process starts to occur soon after the end of the second month of embryonic life. Intramembranous ossification is the formation of a *membrane bone (e.g. a bone of the skull). This starts in the early embryo and is not complete at birth (see fontanelle).... ossification