Glucoside Health Dictionary

Glucoside: From 3 Different Sources


A plant compound containing a glucose and another substance (the bioactive part). A special-case glycoside.
Health Source: Herbal Medical
Author: Health Dictionary
A GLYCOSIDE formed from GLUCOSE.
Health Source: Medical Dictionary
Author: Health Dictionary

Ficus

Ficus spp.

Moraceae

The genus Ficus constitutes an important group of trees with immense medicinal value. It is a sacred tree of Hindus and Buddhists. Among the varied number of species, the most important ones are the four trees that constitute the group “Nalpamaram”, namely, F. racemosa, F. microcarpa, F. benghalensis and F. religiosa (Athi, Ithi, Peral and Arayal respectively).

1. Ficus racemosa Linn. syn. F. glomerata Roxb.

Eng: Cluster fig, Country fig

San: Udumbarah, Sadaphalah

Hin: Gular, Umar

Ben: Jagya dumur

Mal, Tam,

Kan: Athi

Tel: Udambaramu, Paidi

Gular fig, Cluster fig or Country fig, which is considered sacred, has golden coloured exudate and black bark. It is distributed all over India. Its roots are useful in treating dysentery. The bark is useful as a wash for wounds, highly efficacious in threatened abortions and recommended in uropathy. Powdered leaves mixed with honey are given in vitiated condition of pitta. A decoction of the leaves is a good wash for wounds and ulcers. Tender fruits (figs) are used in vitiated conditions of pitta, diarrhoea, dyspepsia and haemorrhages. The latex is administered in haemorrhoids and diarrhoea (Warrier et al, 1995). The ripe fruits are sweet, cooling and are used in haemoptysis, thirst and vomiting (Nadkarni, 1954; Aiyer et al, 1957; Moos, 1976). Nalpamaradi coconut oil, Candanasava, Valiya Arimedastaila, Dinesavalyadi Kuzhambu, Abhrabhasma, Valiya candanaditaila, etc. are some important preparations using the drug (Sivarajan et al, 1994).

It is a moderate to large-sized spreading laticiferous, deciduous tree without many prominent aerial roots. Leaves are dark green and ovate or elliptic. Fruit receptacles are 2-5cm in diameter, sub- globose or pyriform arranged in large clusters on short leafless branches arising from main trunk or large branches. Figs are smooth or rarely covered with minute soft hairs. When ripe, they are orange, dull reddish or dark crimson. They have a pleasant smell resembling that of cedar apples. The bark is rusty brown with a fairly smooth and soft surface, the thickness varying from 0.5-2cm according to the age of the trunk or bark. Surface is with minute separating flakes of white tissue. Texture is homogeneously leathery (Warrier et al, 1995).

Stem-bark gives gluanol acetate, -sitosterol, leucocyanidin-3-O- -D-glucopyrancoside, leucopelargonidin-3-O- -D-glucopyranoside, leucopelargonidin -3-O- -L-rhamnopyranoside, lupeol, ceryl behenate, lupeol acetate and -amyrin acetate. Stem- bark is hypoglycaemic and anti-protozoal. Gall is CVS active. Bark is tonic and used in rinder pest diseases of cattle. Root is antidysenteric and antidiabetic. Leaf is antibilious. Latex is antidiarrhoeal and used in piles. Bark and syconium is astringent and used in menorrhagia (Husain et al, 1992).

2. Ficus microcarpa Linn. f. syn. F. retusa auct. Non. Linn.

San: Plaksah; Hin,

Ben: Kamarup;

Mal: Ithi, Ithiyal;

Tam: Kallicci, Icci;

Kan: Itti;

Tel: Plaksa

Plaksah is the Ficus species with few branches and many adventitious roots growing downward. It is widely distributed throughout India and in Sri Lanka, S. China, Ryuku Isles and Britain. Plakasah is one of the five ingredients of the group panchvalkala i.e, five barks, the decoction of which is extensively used to clear ulcers and a douche in leucorrhoea in children. This decoction is administered externally and internally with satisfactory results. Plaksah is acclaimed as cooling, astringent, and curative of raktapitta doshas, ulcers, skin diseases, burning sensation, inflammation and oedema. It is found to have good healing property and is used in preparation of oils and ointments for external application in the treatment of ulcers (Aiyer and Kolammal, 1957). The stem-bark is used to prepare Usirasava, Gandhataila, Nalpamaradi taila, Valiya marmagulika, etc. (Sivarajan et al, 1994). The bark and leaves are used in wounds, ulcers, bruises, flatulent colic, hepatopathy, diarrhoea, dysentery, diabetes, hyperdipsia, burning sensation, haemaorrhages, erysipelas, dropsy, ulcerative stomatitis, haemoptysis, psychopathy, leucorrhoea and coporrhagia (Warrier et al,1995) F. microcarpa is a large glabrous evergreen tree with few aerial roots. Leaves are short- petioled, 5-10cm long, 2-6cm wide and apex shortly and bluntly apiculate or slightly emarginate. Main lateral nerves are not very prominent and stipules are lanceolate. Fruit receptacles are sessile and globose occurring in axillary pairs. It is yellowish when ripe without any characteristic smell. Bark is dark grey or brown with a smooth surface except for the lenticels. Outer bark is corky and crustaceous thin and firmly adherent to inner tissue. Inner bark is light and flesh coloured with firbrous texture (Warrier et al, 1995). It is also equated with many other species of the genus. viz. F. Singh and Chunekar, 1972; Kapoor and Mitra, 1979; Sharma, 1983).

The bark contains tannin, wax and saponin. Bark is antibilious. Powdered leaves and bark is found very good in rheumatic headache. The bark and leaves are astringent, refrigerant, acrid and stomachic.

3. Ficus benghalensis Linn.

Eng: Banyan tree; San: Nyagrodhah, Vatah;

Hin: Bat, Bargad;

Ben: Bar, Bot; Mar: Vada; Mal: Peral, Vatavriksham;

Tam: Alamaram, Peral;

Kan: Ala;

Tel: Peddamarri;

Guj: Vad

Banyan tree is a laticiferous tree with reddish fruits, which is wound round by aerial adventitious roots that look like many legs. It is found in the Sub-Himalayan tract and Peninsular India. It is also grawn throughout India. It is widely used in treatment of skin diseases with pitta and rakta predominance. Stem-bark, root -bark, aerial roots, leaves, vegetative buds and milky exudate are used in medicine. It improves complexion, cures erysepelas, burning sensation and vaginal disorders, while an infusion of the bark cures dysentery, diarrhoea, leucorrhoea, menorrhagia, nervous disorders and reduces blood sugar in diabetes. A decoction of the vegetative buds in milk is beneficial in haemorrhages. A paste of the leaves is applied externally to abcesses and wounds to promote suppuration, while that of young aerial roots cure pimples. Young twigs when used as a tooth brush strengthen gum and teeth (Nadkarni, 1954; Aiyer and Kolammal, 1957; Mooss,1976). The drug forms an important constituent of formulations like Nalpamaradi Coconut oil, Saribadyasava, Kumkumadi taila, Khadi ra gulika, Valiyacandanadi taila, Candanasava, etc. (Sivarajan et al, 1994). The aerial roots are useful in obstinate vomiting and leucorrhoea and are used in osteomalacia of the limbs. The buds are useful in diarrhoea and dysentery. The latex is useful in neuralgia, rheumatism, lumbago, bruises, nasitis, ulorrhagia, ulitis, odontopathy, haemorrhoids, gonorrhoea, inflammations, cracks of the sole and skin diseases (Warrier et al, 1995).

It is a very large tree up to 30m in height with widely spreading branches bearing many aerial roots functioning as prop roots. Bark is greenish white. Leaves are simple, alternate, arranged often in clusters at the ends of branches. They are stipulate, 10-20cm long and 5-12.5cm broad, broadly elliptic to ovate, entire, coriaceous, strongly 3-7 ribbed from the base. The fruit receptacles are axillary, sessile, seen in pairs globose, brick red when ripe and enclosing male, female and gall flowers. Fruits are small, crustaceous, achenes, enclosed in the common fleshy receptacles. The young bark is somewhat smooth with longitudinal and transverse row of lenticels. In older bark, the lenticels are numerous and closely spaced; outer bark easily flakes off. The fresh cut surface is pink or flesh coloured and exudes plenty of latex. The inner most part of the bark adjoining the wood is nearly white and fibrous (Warrier et al, 1995).

The bark yields flavanoid compounds A, B and C; A and C are identified as different forms of a leucoanthocyanidin and compound B a leucoanthocyanin. All the 3 were effective as hypoglycaemic agents. Leaves give friedelin, -sitosterol, flavonoids- quercetin-3-galactoside and rutin. Heart wood give tiglic acid ester of taraxasterol. Bark is hypoglycemic, tonic, astringent, antidiarrhoeal and antidiabetic. Latex is antirheumatic. Seed is tonic. Leaf is diaphoretic. Root fibre is antigonorrhoeic. Aerial root is used in debility and anaemic dysentery (Husain et al, 1992).

.4. Ficus religiosa Linn.

Eng:Peepal tree, Sacred fig; San:Pippalah, Asvatthah; Hin:Pippal, Pipli, Pipar; Mal:Arayal

Ben: Asvatha;

Tam: Arasu, Asvattam;

Kan: Aswatha;

Tel: Ravi; Mar: Ashvata, Pimpala

Peepal tree or Sacred fig is a large deciduous tree with few or no aerial roots. It is common throughout India, often planted in the vicinity of the temples. An aqueous extract of the bark has an antibacterial activity against Staphylococcus aureus and Escherichia coli. It is used in the treatment of gonorrhoea, diarrhoea, dysentery, haemorrhoids and gastrohelcosis. A paste of the powdered bark is a good absorbent for inflammatory swellings. It is also good for burns. Leaves and tender shoots have purgative properties and are also recommended for wounds and skin diseases. Fruits are laxative and digestive. The dried fruit pulverized and taken in water cures asthma. Seeds are refrigerant and laxative. The latex is good for neuralgia, inflammations and haemorrhages (Warrier et al, 1995). Decoction of the bark if taken in honey subdues vatarakta (Nadkarni, 1954; Aiyer and Kolammal, 1957; Mooss, 1976; Kurup et al, 1979). The important preparations using the drug are Nalpamaradi taila, Saribadyasava, Candanasava, Karnasulantaka, Valiyamarma gulika etc (Sivarajan et al, 1994). branches bearing long petioled, ovate, cordate shiny leaves. Leaves are bright green, the apex produced into a linear-lanceolate tail about half as long as the main portion of the blade. The receptacles occurring in pairs and are axillary, depressed globose, smooth and purplish when ripe. The bark is grey or ash coloured with thin or membranous flakes and is often covered with crustose lichen patches. The outer bark is not of uniform thickness, the middle bark in sections appear as brownish or light reddish brown. The inner part consists of layers of light yellowish or orange brown granular tissue (Warrier et al, 1995).

Bark gives -sitosterol and its glucoside. Bark is hypoglycaemic. Stem bark is antiprotozoal, anthelmintic and antiviral. Bark is astringent, antigonorrheic, febrifuge, aphrodisiac and antidysenteric. Syconium, leaf and young shoot is purgative (Husain et al, 1992).

Agrotechnology: Ficus species can be cultivated in rocky areas, unused lands, or other wastelands of the farmyard. The plant is vegetatively propagated by stem cuttings. A few species are also seed propagated. Stem cuttings of pencil thickness taken from the branches are to be kept for rooting. Rooted cuttings are to be transplanted to prepared pits. No regular manuring is required. Irrigation is not a must as a plant is hardy. The plant is not attacked by any serious pests or diseases. Bark can be collected after 15 years. Ficus species generally has an economic life span of more than hundred years. Hence bark can be regularly collected from the tree. Root, bark, leaves, fruits and latex form the economic parts (Prasad et al,1995).... ficus

Ashoka

Saraca asoca

Caesalpiniaceae

San:Asoka, Gatasokah;

Hin:Asok, Asoka; Ben:Ashok; Mal:Asokam;

Tam: Asogam;

Kan:Asokada, Aksunkara;

Tel: Asokamu, Vanjalamu

Importance: Ashoka, the sacred tree of Hindus and Buddhists, possesses varied medicinal uses. The bark is useful in dyspepsia, fever, dipsia, burning sensation, visceromegaly, colic, ulcers, menorrhagia, metropathy, leucorrhoea and pimples. The leaf juice mixed with cumin seeds is used for treating stomachalagia. The floweres are considered to be uterine tonic and are used in vitiated conditions of pitta, syphilis, cervical adinitis, hyperdipsia, burning sensation, haemorrhoids, dysentery, scabies in children and inflammation. The well-known Ayurvedic preparations are ”Ashokarishta” and “Ashokaghrita”. Ashokarishta is prescribed in leucorrhoea, haematuria, menorrhagia and other diseases of genitourinary system of females.

Distribution: Ashoka is found almost throughout India, except North-Western India, upto 750m. It is also found in the Andaman Islands.

Botany: Saraca asoca (Roxb.) de Wilde. syn. S. indica auct. non Linn. is a medium sized evergreen tree growing upto 9m height with numerous spreading and drooping glabrous branches. Leaves are pinnate, 30-60cm long having 2-3 pairs of lanceolate leaflets. Flowers are orange or orange yellow, arranged in dense corymbs and very fragrant. Fruits are flat black pods, leathery and compressed with 4-8 seeds/pod. Seeds are ellipsoid oblong and compressed. The bark is dark brown to grey or black with a warty surface. The thickness varies from 5mm to 10mm. The entire cut surface turns reddish on exposure to air. Polyalthia longifolia (Annonaceae) is equated with the name Asoka by some (Kapoor & Mitra, 1979; Chunekar, 1982) and is often used as an adulterant of the genuine Asoka bark or as a substitute (Warrier et al,1996).

Agrotechnology: Asoka grows well in areas with well distributed rainfall and in slightly shady areas. Asoka requires soil rich in organic mater and moisture. The best season of planting is June-July. It is also grown in summer, if irrigation facilities are available. The plant is seed propagated. Seeds are formed usually during February-April. Seeds are collected when they are ripen and fall down and are sown after soaking in water for 12 hours on the prepared beds. Seeds germinate within 20 days. The seeds are then planted in polybags. 2-month-old seedlings from the polybags are used for transplanting. Square shaped pits of 60cm depth are taken at 3m spacing and filled with topsoil, sand and dried cowdung. On this the seedlings are planted. Application of FYM at 10kg/tree/year is highly beneficial. Chemical fertilisers are not usually applied. Irrigation during summer months is essential. No serious pests or diseases are generally noted in this crop. If properly cultivated, Asoka can be cut after 20 years and the bark collected. It is cut at a height of 15cm from the soil level. If given irrigation and fertilisers, the cut wood will sprout again and harvested again after 5 years. This can be continued. When it is difficult to cut the tree, the bark can be peeled off from one side first. When the bark grows and cover that part, the other side can be peeled off. This is also continued (Prasad et al, 1997; Karshakasree, 1998).

Properties and activity: Flowers give -sitosterol, flavonoids and flavone glycosides-quercetin, kaempferol-3-O- -D- glucoside, quercetin-3-O- -D-glucoside. The anthocyanins present are pelargonidin-3, 5-diglucoside and cyanadin-3, 5-diglucoside. Bark yields catechol and sterols-(24)-24-methyl cholest-5-en-3 -ol, (22E, 24)-24-ethylcholesta-5, 22-dien-3 -ol and (24)-24-ethyl cholest-5-en-3 -ol, a wax containing n-alkanes, esters and free primary alcohols. Alcoholic extract and glycoside P2 from stem bark is oxytoxic. Aerial part is CNS active, hypothermic, CNS depressant and diuretic. Stem bark is anticancerous, has spasmodic action on rabbit intestine and cardiotonic action in frog and dog. Seed is antifungal. Stem bark is astringent, antileucorrhoeic, antibilious and uterine sedative. Flower is uterine tonic, antidiabetic and antisyphilitic. Stem bark and flower is antibilious (Husain et al, 1992).... ashoka

Eclipta

Eclipta prostrata

Asteraceae

San: Bhrngarajah, Tekarajah;

Hin: Bhamgra, Mocakand, Babri;

Ben: Kesutthe, Kesraj;

Mal: Kannunni, Kayyonni, Kayyunnni;

Tam: Kayyantakara, Kaikeri;

Kan: Kadiggagaraga;

Tel: Guntagalijeran; Arab: Kadim-el-bint

Importance: Eclipta is one of the ten auspicious herbs that constitute the group dasapuspam which is considered to destroy the causative factors of all unhealthy and unpleasant features and bestow good health and prosperity. The members of this group cure wounds and ulcers as well as fever caused by the derangement of the tridosas - vata, pitta and kapha. It is used in hepatitis, spleen enlargements, chronic skin diseases, tetanus and elephantiasis. The leaf promotes hair growth and use as an antidote in scorpion sting. The root is used as an emetic, in scalding of urine, conjuctivitis and as an antiseptic to ulcers and wound in cattle. It is used to prevent abortion and miscarriage and also in cases of uterine pains after the delivery. The juice of the plant with honey is given to infants for expulsion of worms. For the relief in piles, fumigation with Eclipta is considered beneficial. A decoction of the leaves is used in uterine haemorrhage. The paste prepared by mincing fresh plants has got an antiinflammatory effect and may be applied on insect bites, stings, swellings and other skin diseases. In Ayurveda, it is mainly used in hair oil, while in Unani system, the juice is used in “Hab Miskeen Nawaz” along with aconite, triphala, Croton tiglium, Piper nigium, Piper longum, Zingiber officinale and minerals like mercury, sulphur, arsenic, borax, etc. for various types of pains in the body. It is also a constituent of “Roghan Amla Khas” for applying on the hair and of “Majun Murrawah-ul-arwah”.

Distribution: This plant is widely distributed in the warm humid tropics with plenty of rainfall. It grows commonly in moist places as a weed all over plains of India.

Botany: Eclipta prostrata (Linn) Linn. syn. E. alba Hassk. is an annual, erect or postrate herb, often rooting at nodes. Leaves are sessile, 2.5-7.5cm long with white appressed hairs. Floral heads are 6-8 mm in diameter, solitary and white. Fruit is an achene, compressed and narrowly winged. Sometimes, Wedelia calendulacea, which resembles Eclipta prostrata is used for the same purpose.

Properties and activity: The leaves contain stigmasterol, -terthienylmethanol, wedelolactone, dismethylwedelolactone and dismethylwedelolactone-7-glucoside. The roots give hentriacontanol and heptacosanol. The roots contain polyacetylene substituted thiophenes. The aerial part is reported to contain a phytosterol, -amyrin in the n-hexane extract and luteolin-7-glucoside, -glucoside of phytosterol, a glucoside of a triterpenic acid and wedelolactone in polar solvent extract. The polypeptides isolated from the plant yield cystine, glutamic acid, phenyl alanine, tyrosine and methionine on hydrolysis. Nicotine and nicotinic acid are reported to occur in this plant.

The plant is anticatarrhal, febrifuge, antidontalgic, absorbent, antihepatic, CVS active, nematicidal, ovicidal and spasmolytic in activity. The alcoholic extract of entire plant has been reported to have antiviral activity against Ranikhet disease virus. Aqueous extract of the plant showed subjective improvement of vision in the case of refractive errors. The herbal drug Trefoli, containing extracts of the plant in combination with others, when administered to the patients of viral hepatitis, produced excellent results.... eclipta

Garden Rue

Ruta chalepensis

Rutaceae

San: Gucchapatra;

Hin: Pismaram, Sadab, Satari;

Ben: Ermul;

Mal: Aruta, Nagatali;

Tam: Aruvadam, Arvada;

Kan: Sadabu, Nagadali; soppu, Simesdanu;

Tel: Sadapa, Aruda

Importance: Common rue or Garden rue also known as Herb of Grace due to its service in the Roman Catholic Church for sprinkling the holy water among the congregation, is an aromatic perennial herb. The plant is useful in vitiated conditions of kapha and vata, strangury, fever, flatulence, colic, amenorrhoea, epilepsy and hysteria. The oil acts as a stimulant for uterine and nervous systems. The fresh leaves are used for rheumatalgia. The juice obtained from the leaves is given to children for helminthic infections and is good for odontalgia and otalgia (Warrier et al, 1996). The dried leaves, powdered and combined with aromatics, are given as a remedy for dyspepsia and with the fresh leaves a tincture is made which is used as an external remedy in the first stages of paralysis (Nadkarni, 1998).

Distribution: The plant is a native of South Europe and it is found in subtropical countries. It is commonly cultivated in Indian gardens.

Botany: Ruta chalepensis Linn.syn. R. graveolens Linn. var. angustifolia Sensu Hook. f. belongs to the family Rutaceae. It is an aromatic perennial herb growing upto 75cm height. Leaves are compound, shortly petiolate with ultimate segments oblong or obovate-oblong. Flowers are yellow. Fruits are capsules and shortly pedicelled (Warrier et al, 1996).

Agrotechnology: The plant is suited to areas which are about 1000m above mean sea level and with moderate rainfall and sunlight. The plant can be propagated either by seeds or stem cuttings. Seeds are to be sown in seedbeds. Stem cuttings of length 20-25cm are to be planted in polybags for rooting. About 3-4 months old seedlings can be transplanted to pots and harvested when plants attain 6-8 months age. In highlands land is to be ploughed to a fine tilth, mixed with organic manure and seedlings are to be transplanted at a spacing of 45cm between plants. Irrigation is essential during summer months. Regular weeding is to be done. The plant is not attacked by any serious pests and diseases. Harvesting commences from sixth month onwards. The economic part is the whole plant and the oil extracted from it (Prasad et al, 1997).

Properties and activity: Roots contain coumarins-xanthyletin and (-)-byakangelicin. The alkaloids are rutacridone-epoxide, gravacridonol and its monomethyl ether, gravacridonchlorine, furacridone, 1-hydroxy-3-methoxy-N-methylacridone, iso-gravacridonechlorine, dictamine, r-fragarine and skimmianine. Skimmianine is also present in leaves and stem. Leaves and stem also contain graveolinine (1-methyl-2(3’,4’-methylenedioxyphenol)-4-methoxy- quinoline). Aerial parts give coumarins bergapten, xanthotoxin and psoralen. Coumarin- imperatin has also been reported from the plant. Herb contains alkaloids such as kokusagenine, rutamine(methylgraveoline) and graveoline(1-methyl-2(3’,4’- methylenedioxyphenyl)-4-quinoline). Tissue culture of the plant gives furacridone alkaloids-1-hydroxyrutacridone-epoxide, rutagravin and gravacridonol. Gravacridondiol and its glucoside have been obtained from the root tissue culture. The essential oil from leaves, stem and root yielded aliphatic ketones including 2-nonanone (10-35%), undecyl-2-acetate (0.5-15%), 2-nonyl acetate (trace-10%), nonylacetate, nonanol, 2-nonylpropionate, 2- nonylpropionate, 2-undecanol and its esters. The oil from roots gave pregeijerene also.

The plant is spasmolytic which is due to the presence of bergapten, xanthotoxin, the essential oil and a coumarin. It is also antispasmodic, emmenagogue, irritant, abortifacient and anti-bacterial. Leaf is analgesic, antirheumatic, antihysteric and anthelmintic (Husain et al, 1992).... garden rue

Green Chiretta

Andrographis paniculata

Acanthaceae

San: Bhunimbah, Kiratatiktah

Hin: Kakamegh, Kalpanath

Ben: Kalmegh

Mal: Nilaveppu, Kiriyattu Tam: Nilavempu Kan: Kreata

Importance: Kalmegh, the Great or Green Chiretta is a branched annual herb. It is useful in hyperdipsia, burning sensation, wounds, ulcers, chronic fever, malarial and intermittent fevers, inflammations, cough, bronchitis, skin diseases, leprosy, pruritis, intestinal worms, dyspepsia, flatulence, colic, diarrhoea, dysentery, haemorrhoids and vitiated conditions of pitta (Warrier et al, 1993). It is used to overcome sannipata type of fever, difficulty in breathing, hemopathy due to the morbidity of kapha and pitta, burning sensation, cough, oedema, thirst, skin diseases, fever, ulcer and worms. It is also useful in acidity and liver complaints (Aiyer and Kolammal, 1962). The important preparations using the drug are Tiktakagheta, Gorocandi gulika, Candanasava, Panchatiktam kasaya, etc. (Sivarajan et al, 1994). A preparation called “Alui” is prepared by mixing powdered cumin (Cuminium cyminum) and large cardamom (Amomum subulatum) in the juice of this plant and administered for the treatment of malaria (Thakur et al, 1989). It is also a rich source of minerals.

Distribution: The plant is distributed throughout the tropics. It is found in the plains of India from U.P to Assam, M.P., A.P, Tamil Nadu and Kerala, also cultivated in gardens.

Botany: Andrographis paniculata (Burm.f.) Wall ex.

Nees belongs to the family Acanthaceae. It is an erect branched annual herb, 0.3-0.9m in height with quadrangular branches. Leaves are simple, lanceolate, acute at both ends, glabrous, with 4-6 pairs of main nerves. Flowers are small, pale but blotched and spotted with brown and purple distant in lax spreading axillary and terminal racemes or panicles. Calyx-lobes are glandular pubescent with anthers bearded at the base. Fruits are linear capsules and acute at both ends. Seeds are numerous, yellowish brown and sub-quadrate (Warrier et al,1993).

Another species of Andrographis is A. echioides (Linn.) Nees. It is found in the warmer parts of India. The plant is a febrifuge and diuretic. It contains flavone-echiodinin and its glucoside-echioidin (Husain et al, 1992).

Agrotechnology: The best season of planting Andrographis is May-June. The field is to be ploughed well, mixed with compost or dried cowdung and seedbeds of length 3m, breadth 1/2m and 15cm height are to be taken at a distance of 3m. The plant is seed propagated. Seeds are to be soaked in water for 6 hours before sowing. Sowing is to be done at a spacing of 20cm. Seeds may germinate within 15-20 days. Two weedings, first at one month after planting and the second at 2 month after planting are to be carried out. Irrigation during summer months is beneficial. The plant is not attacked by any serious pests or diseases. Flowering commences from third month onwards. At this stage, plant are to be collected, tied into small bundles and sun-dried for 4-5 days. Whole plant is the economic part and the yield is about 1.25t dried plants/ha (Prasad et al, 1997).

Properties and activity: Leaves contain two bitter substances lactone “andrographolid” and “kalmeghin”. The ash contains sodium chloride and potassium salts. Plant is very rich in chlorophyte. Kalmeghin is the active principle that contains 0.6% alkaloid of the crude plant. The plant contains diterpenoids, andrographolide, 14-deoxy-11-oxo-andrographolide, 14-deoxy-11,12-dihydroandrographolide, 14-deoxy andrographolide and neoandrographolide (Allison et al, 1968). The roots give flavones-apigenin-7,4-dio-O-methyl ether, 5-hydroxy-7,8,2’,3’- tetramethoxyflavone, andrographin and panicolin and -sitosterol (Ali et al, 1972; Govindachari et al, 1969). Leaves contain homoandrographolide, andrographosterol and andrographone.

The plant is vulnerary, antipyretic, antiperiodic, anti-inflammatory, expectorant, depurative, sudorific, anthelmintic, digestive, stomachic, tonic, febrifuge and cholagogue. The plant is antifungal, antityphoid, hepatoprotective, antidiabetic and cholinergic. Shoot is antibacterial and leaf is hypotensive(Garcia et al, 1980). This is used for the inflammation of the respiratory tract. In China, researchers have isolated the andrographolide from which soluble derivative such as 14-deoxy-11, 12-dehydro-andrographolide which forms the subject of current pharmacological and clinical studies. Apigenin 7,4’-O-dimethyl ether isolated from A. paniculata exhibits dose dependent, antiulcer activity in shay rat, histamine induced ulcer in guinea pigs and aspirin induced ulcers in rats. A crude substance isolated from methanolic extract of leaves has shown hypotensive activity. Pre-treatment of rats with leaf (500mg/kg) or andrographolide (5mg/kg) orally prevented the carbon tetrachloride induced increase of blood serum levels of glutamate-oxaloacetate transaminase in liver and prevented hepatocellular membrane.... green chiretta

Acacia Arabica

Willd. var. indica Benth.

Synonym: A. nilotica (Linn.) Delile subsp. indica (Benth.) Brenan.

Family: Mimosaceae.

Habitat: Throughout the drier parts of India.

English: Babul, Black Babul, Indian Gum arabic tree.

Ayurvedic: Babbuula, Babbuuri, Baavari, Aabhaa, Shuulikaa, Shitaka, Kinkiraata, Yugmakantaka, Sukshmapatra, Pitapushpaka.

Unani: Aqaaqia, Babuul, Kikar, Mughilaan, Samur.

Siddha/Tamil: Karu-velamaram, Karuvelei. Velampisin (gum).

Action: Stembark—astringent, spasmolytic, hypoglycaemic. Gum—demulcent (soothing agent for inflammatory conditions of the respiratory, digestive and urinary tracts). Pods—used in urogenital disorders. Seeds—hypoglycaemic in normal rats; no such effect in diabetic rats. Seed oil—antifungal. Flowers, pods and gum resin—used in diarrhoea and dysentery.

Along with other therapeutic applications, The Ayurvedic Pharmacopoeia of India indicates the use of stembark in acute diarrhoea and helminthiasis.

Tannin contents of the bark varies considerably (12-20%). Several poly- phenolic compounds have been reported in the bark, also in the pods. The whole pod contains 12-19% tannins and 18-27% after the removal of seeds.

The seeds of A. benthamii, A. nilotica ssp. subulata, probably same as ssp. indica, are considered hypoglycaemic. Some seed components stimulate insulin secretion by beta cells.

The gum contains galactose; l-ara- binose, l-rhamnose and aldobiouronic acids, also arabinobioses.

The flowers contain flavonoids— kaempferol-3-glucoside, iso-quercitrin and leucocyanidin.

Dosage: Stembark—20-30 g for decoction. (API Vol. I.)... acacia arabica

Acacia Senegal

Willd.

Synonym: A. verek Guillem and Perr.

Family: Mimosaceae.

Habitat: Native to Sudan. Cultivated in dry parts of western India.

English: Gum arabic tree.

Ayurvedic: Shveta Babbuula.

Action: The tree yields the true Gum arabic of commerce. Mucilaginous, demulcent, emulsifying agent. Used as an ingredient in compounds for treatment of diarrhoea, catarrh.

Bechic, antihaemorrhagic, antiinflammatory. Stembark—antiinflammatory, spasmolytic. Root— used for dysentery and urinary discharges.

The gum consists mainly of arabin. It is the salt of an organic acid, arabic acid, with metals such as calcium, magnesium and potassium.

The stembark gives octacosanol, beta-amyrin, uvaol, beta-stosterol and its glucoside and erthrodiol. An alkaloid, dimethyltryptamine has been isolated from the leaves.... acacia senegal

Achillea Millefolium

Linn.

Synonym: A. lanulosa Nutt.

Family: Compositae; Asteraceae.

Habitat: The western Himalayas from Kashmir to Kumaon.

English: Milfoil, Yarrow, Thousand Leaf.

Unani: Biranjaasif. National Formulary of Unani Medicine also equates Leonurus cardica Linn. (Labiatae) with Biranjaasif.

Folk: Gandana, Rojmari.

Action: Anti-inflammatory, anti- spasmodic (used in cold, flatulent colic, heartburn), emmenagogue, cicatrizant, antidysenteric, anti- haemorrhagic, antipyretic, diaphoretic, diuretic, urinary antiseptic.

Key application: In dyspeptic ailments, such as mild, spastic discomforts of the gastrointestinal tract. As astringent, antispasmodic, choleretic, antibacterial. (German Commission E.) As diaphoretic. (The British Herbal Pharmacopoeia.) Internally for feverish conditions, common cold and digestive complaints; topically for slow-healing wounds and skin inflammations. (The British Herbal Compendium.)

The plant contains flavonoids, alkaloids (achilleine), polyacetylenes, triterpenes, coumarins, tannins, salicylic acid, a volatile oil containing linalool, camphor, sabinene, chamazu- lene and other azulenes.

Sesquiterpene lactones are bitter and tonic. Achilleine helps arrest internal and external bleeding. Flavonoids contribute to the antispasmodic action.

The flavonoid apigenin is anti-inflammatory, antiplatelet and spasmolytic. Alkaloids and bases are anti- inflammatory. Alkaloid betoncine is haemostatic. Salicylic acid is anti- inflammatory. Chamazulene is anti- inflammatory and antiallergenic. (Natural Medicines Comprehensive Database, 2007.)

An extract of the plant was found to be rich in luteolin or luteolin 7- glucoside and can be used for the treatment of hyperpigmentation of skin.... achillea millefolium

Andrographis Echioides

Nees

Family: Acanthaceae.

Habitat: Warmer parts of India. Folk: Ranchimani (Maharashtra).

Action: Febrifuge, diuretic.

The plant contains a flavone, echio- dinin, and its glucoside, echioidin. EtOH (50%) extract of the plant exhibited diuretic activity in animal studies.... andrographis echioides

Atylosia Scarabaeoides

(L.) Benth.

Family: Papilionaceae; Fabaceae.

Habitat: Throughout India; up to 1,800 m in the western Himalayas.

Ayurvedic: Vana-kulattha.

Folk: Jangli Tur, Kulthi.

Action: Antidysenteric, anticholerin, febrifuge; also used in anaemia, anasarca and hemiplegia. Seeds— taeniafuge.

A flavone glucoside, atyloside, has been isolated from the leaves.... atylosia scarabaeoides

Cucurbits

Cucurbitaceae

The family Cucurbitaceae includes a large group of plants which are medicinally valuable. The important genera belonging to the family are Trichosanthes, Lagenaria, Luffa, Benincasa, Momordica, Cucumis, Citrullus, Cucurbita, Bryonopsis and Corallocarpus. The medicinally valuable species of these genera are discussed below.

1. Trichosanthes dioica Roxb.

Eng: Wild Snake-gourd; San: Meki,Pargavi, Parvara, Patola;

Hin: Palval, Parvar

Ben: Potol;

Mal: Kattupatavalam, Patolam;

Tam: Kombuppudalai;

Tel: Kommupotta

Wild snake-gourd is a slender-stemmed, extensively climbing, more or less scabrous and woolly herb found throughout the plains of N. India, extending to Assam and W. Bengal. Tendrils are 2-4 fid. Leaves are 7.5x5cm in size, ovate-oblong, cordate, acute, sinuate- dentate, not lobed, rigid, rough on both surface and with a petiole of 2cm. Flowers are unisexual. Male flowers are not racemed but woolly outside. Calyx tube is 4.5cm long, narrow, teeth linear and erect. Anthers are free. Fruit is 5.9cm long, oblong or nearly spherical, acute, smooth and orange-red when ripe. Seeds are half-ellipsoid, compressed and corrugated on the margin (Kirtikar and Basu, 1988). The unripe fruit of this is generally used as a culinary vegetable and is considered very wholesome and specially suited for the convalescent. The tender shoots are given in decoction with sugar to assist digestion. The seeds are useful for disorders of the stomach. The leaf juice is rubbed over the chest in liver congestion and over the whole body in intermittent fevers (Nadkarni, 1998). The fruit is used as a remedy for spermatorrhoea. The fresh juice of the unripe fruit is often used as a cooling and laxative adjunct to some alterative medicines. In bilious fever, a decoction of patola leaves and coriander in equal parts is given. The fruit in combination with other drugs is prescribed in snakebite and scorpion sting (Kirtikar and Basu, 1988).

Fruits contain free amino acids and 5-hydroxy tryptamine. Fatty acids from seeds comprise elaeostearic, linoelic, oleic and saturated acids. The aerial part is hypoglycaemic. Leaf and root is febrifuge. Root is hydragogue, cathartic and tonic. Unripe leaf and fruit is laxative (Husain et al, 1992). The plant is alterative and tonic. Leaves are anthelmintic. Flower is tonic and aphrodisiac. The ripe fruit is sour to sweet, tonic, aphrodisiac, expectorant and removes blood impurities.

The other important species belonging to the genus Trichosanthes are as follows.

T. palmata Roxb. T. cordata Roxb. T. nervifolia Linn.

T. cucumerina Linn.

T. anguina Linn.

T. wallichiana Wight. syn. T. multiloba Clarke

2. Lagenaria vulgaris Ser. syn. Cucurbita Lagenaria Linn. ; Roxb.

Eng: Bottle gourd San: Alabu Hin: Lauki, Jangli-khaddu

Ben: Lau, Kodu

Mal: Katuchuram, Churakka

Tam: Soriai-kay

Tel: Surakkaya

Bottle gourd is a large softly pubescent climbing or trailing herb which is said to be indigenous in India, the Molucas and in Abyssinia. It has stout 5-angled stems with bifid tendrils. Leaves are ovate or orbiculate, cordate, dentate, 5-angular or 5-lobed, hairy on both surfaces. Flowers are large, white, solitary, unisexual or bisexual, the males long and females short peduncled. Ovary is oblong, softly pubescent with short style and many ovules. Fruits are large, usually bottle or dumb-bell-shaped, indehiscent and polymorphous. Seeds are many, white, horizontal, compressed, with a marginal groove and smooth. There are sweet fruited and bitter-fruited varieties (Kirtikar and Basu, 1988). The fruit contains a thick white pulp which, in the cultivated variety (kodu) is sweet and edible, while in the smaller wild variety (tamri) it is bitter and a powerful purgative. The seeds yield clear limpid oil which is cooling and is applied to relieve headache. The pulp of the cultivated forms is employed as and adjunct to purgatives and considered cool, diuretic and antibilious, useful in cough, and as an antidote to certain poisons. Externally it is applied as a poultice. The leaves are purgative and recommended to be taken in the form of decoction for jaundice (Nadkarni, 1998). In the case of sweet-fruited variety, the stem is laxative and sweet. The fruit is sweet oleagenous, cardiotonic, general tonic, aphrodisiac, laxative and cooling. In the case of bitter-fruited variety, the leaves are diuretic, antibilious; useful in leucorrhoea, vaginal and uterine complaints and earache. The fruit is bitter, hot, pungent, emetic, cooling, cardiotonic, antibilious; cures asthma, vata, bronchitis, inflammations ulcers and pains.

3. Luffa acutangula (Linn.) Roxb.

Eng: Ridged gourd; San: Dharmargavah, Svadukosataki;

Hin: Tori, Katitori;

Ben: Ghosha

Mal: Peechil, Peechinga;

Tam: Pikangai, Prikkangai;

Tel: Birakaya;

Kan: Kadupadagila

Ridged gourd or ribbed gourd is a large monoecious climber cultivated throughout India. It is with 5-angled glabrous stems and trifid tendrils. Leaves are orbicular-cordate, palmately 5-7 lobed, scabrous on both sides with prominent veins and veinlets. Flowers are yellow, males arranged in 12-20 flowered axillary racemes. Female flowers are solitary, arranged in the axils of the males. Ovary is strongly ribbed. Fruits are oblong-clavate with 10-sharp angles 15-30cm long, tapering towards the base. Seeds are black, ovoid-oblong, much compressed and not winged (Warrier et al, 1995). The leaves are used in haemorrhoids, leprosy, granular-conjunctivitis and ringworm. The seeds are useful in dermatopathy. The juice of the fresh leaves is dropped into the eyes of children in granular conjunctivitis, also to prevent the lids from adhering at night on account of excessive meihomian secretion (Nadkarni, 1998). Fruits are demulcent, diuretic, tonic, expectorant, laxative and nutritive. The seeds are bitter, emetic, cathartic, expectorant and purgative.

The other important species of the genus Luffa are:

L. aegyptiaca Mill.

L. acutangula var. amara Clarke

L. echinata Roxb.

4. Benincasa hispida (Thumb.) Cogn. syn. B. cerifera Savi.

Eng: Ash gourd, White gourd melon; San: Kusmandah;

Hin: Petha, Raksa;

Ben: Kumra

Mal: Kumpalam;

Tam: Pusanikkai;

Kan: Bile Kumbala;

Tel: Bodigummadi

Ash gourd or White gourd melon is a large trailing gourd climbing by means of tendrils which is widely cultivated in tropical Asia. Leaves are large and hispid beneath. Flowers are yellow, unisexual with male peduncle 7.5-10cm long and female peduncle shorter. Fruits are broadly cylindric, 30-45cm long, hairy throughout and ultimately covered with a waxy bloom. The fruits are useful in asthma, cough, diabetes, haemoptysis, hemorrhages from internal organs, epilepsy, fever and vitiated conditions of pitta. The seeds are useful in dry cough, fever, urethrorrhea, syphilis, hyperdipsia and vitiated conditions of pitta (Warrier et al,1993). It is a rejuvenative drug capable of improving intellect and physical strength. In Ayurveda, the fresh juice of the fruit is administered as a specific in haemoptysis and other haemorrhages from internal organs. The fruit is useful in insanity, epilepsy and other nervous diseases, burning sensation, diabetes, piles and dyspepsia. It is a good antidote for many kinds of vegetable, mercurial and alcoholic poisoning. It is also administered in cough, asthma or respiratory diseases, heart diseases and catarrah. Seeds are useful in expelling tapeworms and curing difficult urination and bladder stones. The important formulations using the drug are Kusmandarasayana, Himasagarataila, Dhatryadighrita, Vastyamantakaghrita, Mahaukusmandakaghrita, etc. (Sivarajan et al, 1994).

Fruits contain lupeol, -sitosterol, n-triacontanol, vitamin B, mannitol and amino acids. The fruit is alterative, laxative, diuretic, tonic, aphrodisiac and antiperiodic. Seed and oil from seed is anthelmintic (Husain et al, 1992).

5. Momordica charantia Linn.

Eng: Bitter gourd, Carilla fruit San: Karavellam

Hin: Karela, Kareli

Mal: Kaypa, Paval

Tam: Pavakkai, Paval, Pakar

Tel: Kakara

Bitter gourd or Carilla fruit is a branched climbing annual which is cultivated throughout India. It is a monoecious plant with angled and grooved stems and hairy or villous young parts. Tendrils are simple, slender and elongate. Leaves are simple, orbicular, cordate and deeply divided into 5-7 lobes. Flowers are unisexual, yellow and arranged on 5-10cm long peduncles. Fruits are 5-15cm long with 3-valved capsules, pendulous, fusiform, ribbed and beaked bearing numerous triangular tubercles. Seeds are many or few with shining sculptured surface. The roots are useful in coloptosis and ophthalmopathy. The leaves are useful in vitiated conditions of pita, helminthiasis, constipation, intermittent fever, burning sensation of the sole and nyctalopia. The fruits are useful in skin diseases, leprosy, ulcers, wounds, burning sensation, constipation, anorexia, flatulence, colic, helminthiasis, rheumatalgia, gout, diabetes, asthma, cough, dysmenorrhoea, impurity of breast milk, fever and debility. Seeds are useful in the treatment of ulcers, pharyngodynia, and obstructions of the liver and spleen. The leaves and fruits are used for external application in lumbago, ulceration and bone fractures and internally in leprosy, haemorrhoids and jaundice (Warrier et al, 1995). The drug improves digestion, calms down sexual urge, quells diseases due to pitta and kapha and cures anaemia, anorexia, leprosy, ulcers, jaundice, flatulence and piles. Fruit is useful in gout, rheumatism and complaints of liver and spleen (Nadkarni, 1954; Aiyer and Kolammal, 1966; Mooss, 1976; Kurup et al, 1979). Kaccoradi taila is an important preparation using the drug (Sivarajan et al, 1994).

The seeds give triterpene glycosides, named momordicosides A, B, C, D and E, which are glycosides of cucurbit-5-en-triol, tetraol or pentaol. Leaves and vines give tetracyclic triterpenes-momordicines I, II and III (bitter principles). Immature fruits give several non-bitter and 2 bitter cucurbitacin glycosides. Four of the non-bitter glycosides, momordicosides F1, F2, G and I and the bitter momordicosides; K and L have also been characterized. Fruits, seeds and tissue culture give a polypeptide which contained 17 types of amino acids and showed hypoglycaemic activity. Fruits also give 5-hydroxy tryptamine and a neutral compound charantin (a steroidal glucoside), diosgenin, cholesterol, lanosterol and -sitosterol. Leaf is emetic, purgative and antibilious. Fruit is stomachic, tonic, carminative, febrifuge, antirheumatic and hypoglycaemic. Root is astringent. Fruit and leaf is anti-leprotic. Fruit, leaf and root are abortifacient and anti-diabetic. Leaf and seed is anthelmintic. Seed oil possesses antifeeding and insecticidal properties. Unsaponifiable matter from seed oil exhibited pronounced inhibitory activity against gram negative bacteria. Seed and fruit are hypoglycaemic, cytotoxic and anti-feedant (Husain et al, 1992).

Other important species belonging to the genus Momordica are as follows.

M. dioica Roxb.

M. cochinchinensis Spreng.

M. tuberosa Cogn.

M. balsamina Linn.

6. Cucumis melo Linn. syn. C. melo Linn. var. cultis Kurz., C. pubescens

Willd., C. callosus (Rottl.) Cogn.

Eng: Sweet melon San,

Hin: Kharbuja

Ben: Kharmul

Mal: Mulam

Tam: Chukkari-kai, Thumatti-kai, Mulampazham

Tel: Kharbuja-doshavSweet melon is a creeping annual extensively cultivated throughout India, found wild in India, Baluchistan and tropical Africa. The stem is creeping, angular and scabrous. Leaves are orbicular-reniform in outline, 5-angled or lobed, scabrous on both surfaces and often with soft hairs. Lobes of leaves are not very deep nor acute and with 5cm long petiole. Female peduncle is 5cm. Fruit is spherical, ovoid, elongate or contorted, glabrous or somewhat hairy, not spinous nor tuberculate.

Cucumis melo includes two varieties, namely,

C. melo var. momordica syn. C. momordica Roxb.

C. melo var. utilissimus Duthie & Fuller. syn. C. utilissimus Roxb.

The fruit is eaten raw and cooked. Its pulp forms a nutritive, demulcent, diuretic and cooling drink. It is beneficial as a lotion in chronic and acute eczema as well as tan and freckles and internally in cases of dyspepsia. Pulp mixed with cumin seeds and sugar candy is a cool diet in hot season. Seeds yield sweet edible oil which is nutritive and diuretic, useful in painful discharge and suppression of urine. The whole fruit is useful in chronic eczema (Kirtikar & Basu, 1988).

Seeds contain fatty acids-myristic, palmitic, oleic, linoleic; asparagine, glutamine, citrulline, lysine, histidine, arginine, phenylalanine, valine, tyrosine, leucine, iso-leucine, methionine, proline, threonine, tryptophan and crystine. Seed is tonic, lachrymatory, diuretic and urease inhibitor. Fruit pulp is eczemic. Fruit is tonic, laxative, galactagogue, diuretic and diaphoretic. The rind is vulnerary (Husain et al, 1992).

7. Cucumic sativus Linn.

Eng: Cucumber, Common cucumber; San: Trapusah;

Hin,

Ben: Khira;

Mal: Vellari

Tam: Vellarikkai, Pippinkai;

Kan: Mullusavte;

Tel: Dosekaya

Cucumber is a climbing annual which is cultivated throughout India, found wild in the Himalayas from Kumaon to Sikkim. It is a hispidly hairy trailing or climbing annual. Leaves are simple, alternate, deeply cordate, 3-5 lobed with both surfaces hairy and denticulate margins. Flowers are yellow, males clustered, bearing cohering anthers, connective crusted or elevated above the cells. Females are solitary and thickly covered with very bulbous based hairs. Fruits are cylindrical pepo of varying sizes and forms. Seeds are cream or white with hard and smooth testa. The fruits are useful in vitiated conditions of pitta, hyperdipsia, burning sensation, thermoplegia, fever, insomnia, cephalgia, bronchitis, jaundice, haemorrhages, strangury and general debility. The seeds are useful in burning sensation, pitta, constipation, intermittent fevers, strangury, renal calculus, urodynia and general debility (Warrier et al, 1994). The leaves boiled and mixed with cumin seeds, roasted, powdered and administered in throat affections. Powdered and mixed with sugar, they are powerful diuretic (Nadkarni, 1998). The fruits and seeds are sweet, refrigerant, haemostatic, diuretic and tonic. Other important species belonging to the genus are:

C. trigonus Roxb. syn. C. pseudo-colocynthis

C. prophetarum Linn.

8. Citrullus colocynthis (Linn.) Schrader. syn. Cucumis colocynthis Linn.

Eng: Colocynth, Bitter apple; San: Visala, Mahendravaruni;

Hin: Badi indrayan, Makkal

Ben: Makhal;

Mal: Kattuvellari (Valutu), Valiya pekkummatti;

Tel: Etti-puchcha

Tam: Paitummatti, Petummatti;

Colocynth or Bitter apple is found, cultivated and wild, throughout India in warmer areas. It is an extensively trailing annual herb with bifid tendrils angular branching stems and wooly tender shoots. Leaves are deeply divided, lobes narrow thick, glabrous or somewhat hairy. Flowers are unisexual, yellow, both males and females solitary and with pale-yellow corolla. Fruit is a globose or oblong fleshy indehiscent berry, 5-7.5cm in diameter and variegated with green and white. Seeds are pale brown. The fruits are useful in tumours, ascites, leucoderma, ulcers, asthma, bronchitis, urethrorrhea, jaundice, dyspepsia, constipations, elephantiasis, tubercular glands of the neck and splenomegaly (Warrier et al, 1994). It is useful in abnormal presentations of the foetus and in atrophy of the foetus. In addition to the above properties, the root has a beneficial action in inflammation of the breasts, pain in the joints; externally it is used in ophthalmia and in uterine pains. The fruit and root, with or without is rubbed into a paste with water and applied to boils and pimples. In rheumatism, equal parts of the root and long pepper are given in pill. A paste of the root is applied to the enlarged abdomen of children (Kirtikar and Basu, 1988). The fruit is useful in ascites, biliousness, jaundice, cerebral congestion, colic, constipation dropsy, fever, worms and sciatica. Root is given in cases of abdominal enlargement, cough, asthma, inflammation of the breast, ulcers, urinary diseases and rheumatism. Oil from seeds is used for poisonous bites, bowel complaints, epilepsy and also for blackening the hair (Nadkarni, 1954; Dey, 1980). The important formulations using the root and fruit are Abhayarista, Mahatiktakam kasaya, Manasamitravatakam, Cavikasava, Madhuyastyadi taila, etc. (Sivarajan et al, 1994). The powder is often used as an insecticide. The extract should never be given without some aromatic to correct its griping tendency (Nadkarni, 1998).

Fruit contains a glycoside- colocynthin, its aglycone- -elaterin, citrulluin, citrullene and citrullic acid. Unripe fruit contains p-hydroxy benzyl methyl ester. Roots contain - elaterin and hentriacontane (Husain et al, 1992). Colocynth is, in moderate doses, drastic, hydrogogue, cathartic and diuretic. In large doses, it is emetic and gastro-intestinal irritant and in small doses, it is expectorant and alterative. Colocynthin is a cathartic and intensely bitter principle. It has a purgative action. All parts of the plant are very bitter. The fruit has been described as cathartic (Nadkarni, 1982).

9. Citrullus vulgaris Schrad. syn. C. lanatus (Thunb.) Mats. & Nakai.

Eng: Water melon; San: Tarambuja;

Hin: Tarbuj;

Ben: Tarbuz

Mal: Thannimathan;

Tam: Pitcha, Dharbusini

Watermelon is an extensively climbing annual which is largely cultivated throughout India and in all warm countries. It has thick angular branching stems. Tendrils are bifid, stout and pubescent. Leaves are long, deeply divided or moderately lobed, glabrous or somewhat hairy and hardly scabrous. Petiole is a little shorter than the limb and villous. Calyx-lobes are narrowly lanceolate, equalling the tube. Corolla is yellow within, greenish outside and villous. Lobes are ovate-oblong, obtuse and prominently 5-nerved. Fruit is sub-globose or ellipsoid, smooth, greenish or clouded, often with a glaucous waxy coating. Flesh is juicy, red or yellowish white. Seeds are usually margined. C. vulgaris var. fistulosus Duthie & Fuller. syn. C. fistulosus has its fruit about the size of small turnip, the seeds of which are used medicinally. The fruit is tasteless when unripe and sweet when ripe. The unripe fruit is used to cure jaundice. Ripe fruit cures kapha and vata and causes biliousness. It is good for sore eyes, scabies and itching. The seeds are tonic to the brain and used as a cooling medicine. An emulsion of the seeds is made into a poultice with the pounded leaves and applied hot in cases of intestinal inflammations (Kirtikar and Basu, 1988). Fruit juice is good in quenching thirst and it is used as an antiseptic in typhus fever with cumin and sugar. It is used as a cooling drink in strangury and affections of urinary organs such as gonorrhoea; in hepatic congestion and intestinal catarrh. The bitter watermelon of Sind is known as “Kirbut” and is used as a purgative.

Seeds yield a fixed oil and proteids; citrullin. Seeds are cooling, demulcent, diuretic, vermifuge and nutritive. Pulp is cooling and diuretic. Fruit-juice is cooling and refreshing (Nadkarni, 1982).

10. Curcurbita pepo Linn. syn. Pepo vulgaris et P. verrucosus Moench

Meth.

Eng: Pompion, Pumpkin, Vegetable Marrow; San: Karkaru, Kurkaru, Kushmandi

Hin,

Ben: Kadimah, Konda, Kumra, Safedkkadu;

Mal: Mathan, Matha

Tel: Budadegummadi, Pottigummadi

Pompion or Pumpkin is a climbing herb which is considered to be a native of America and cultivated in many parts of India. The stem and leaves are with a harsh prickly armature. Foliage is stiff, more or less rigid and erect. Leaves are with a broad triangular pointed outline and often with deep lobes. Corolla is mostly with erect or spreading (not drooping) pointed lobes, the tube narrowing towards the base. Peduncle is strongly 5-angled and little or much expanding near the fruit. The fruit is cooling and astringent to the bowels, increases appetite, cures leprosy, ‘kapha and vata’, thirst, fatigue and purifies the blood. The leaves are used to remove biliousness. Fruit is good for teeth, throat and eyes and allays thirst. Seeds cure sore chests, haemoptysis, bronchitis and fever. It is good for the kidney and brain. The leaves are used as an external application for burns. The seeds are considered anthelmintic. The seeds are largely used for flavouring certain preparations of Indian hemp, and the root for a nefarious purpose, viz., to make the preparation more potent. The seeds are taeniacide, diuretic and demulcent. The fruit is cooling, laxative and astringent. The leaves are digestible, haematinic and analgesic.

The other important species belonging to the genus Cucurbita is C. maxima Duchena, the seeds of which are a popular remedy for tape-worm and oil as a nervine tonic (Kirtikar & Basu, 1988).

11. Corallocarpus epigaeus Benth. ex Hook. f. syn. Bryonia epigaea Wight.

San: Katunahi;

Hin: Akasgaddah;

Mal: Kadamba, Kollankova

Tam: Akashagarudan, Gollankovai;

Tel: Murudonda, Nagadonda

Corallocarpus is a prostrate or climbing herb distributed in Punjab, Sind, Gujarat, Deccan, Karnataka and Sri Lanka. It is monoecious with large root which is turnip-shaped and slender stem which is grooved, zigzag and glabrous. Tendrils are simple, slender and glabrous. Leaves are sub-orbicular in outline, light green above and pale beneath, deeply cordate at the base, angled or more or less deeply 3-5 lobed. Petiole is long and glabrous. Male flowers are small and arranged at the tip of a straight stiff glabrous peduncle. Calyx is slightly hairy, long and rounded at the base. Corolla is long and greenish yellow. Female flowers are usually solitary with short, stout and glabrous peduncles. Fruit is stalked, long, ellipsoid or ovoid. Seeds are pyriform, turgid, brown and with a whitish corded margin. It is prescribed in later stages of dysentery and old veneral complaints. For external use in chronic rheumatism, it is made into a liniment with cumin seed, onion and castor oil. It is used in case of snakebite where it is administered internally and applied to the bitten part. The root is given in syphilitic rheumatism and later stages of dysentery. The plant is bitter, sweet, alexipharmic and emetic. The root is said to possess alterative and laxative properties (Kirtikar and Basu, 1988). Root contains a bitter principle like Breyonin (Chopra et al, 1980).

Agrotechnology: Cucurbits can be successfully grown during January-March and September- December. For the rainfed crop, sowing can also be started after the receipt of the first few showers.

Pits of 60cm diameter and 30-45cm depth are to be taken at the desired spacing. Well rotten FYM or vegetable mixture is to be mixed with topsoil in the pit and seeds are to be sown at 4-5/pit. Unhealthy plants are to be removed after 2 weeks and retained 2-3 plants/pit. FYM is to be applied at 20-25t/ha as basal dose along with half dose of N (35kg/ha) and full dose of P (25kg) and K (25kg). The remaining dose of N (35kg) can be applied in 2 equal split doses at fortnightly intervals. During the initial stages of growth, irrigation is to be given at an interval of 3-4 days and at alternate days during flowering and fruiting periods. For trailing cucumber, pumpkin and melon, dried twigs are to be spread on the ground. Bitter gourd, bottle gourd, snake gourd and ash gourd are to be trailed on Pandals. Weeding and raking of the soil are to be conducted at the time of fertilizer application. Earthing up may be done during rainy season. The most dreaded pest of cucurbits is fruit flies which can be controlled by using fruit traps, covering the fruits with polythene, cloth or paper bags, removal and destruction of affected fruits and lastly spraying with Carbaryl or Malathion 0. 2% suspension containing sugar or jaggery at 10g/l at fortnightly intervals after fruit set initiation. During rainy season, downy mildew and mosaic diseases are severe in cucurbits. The former can be checked by spraying Mancozeb 0.2%. The spread of mosaic can be checked by controlling the vectors using Dimethoate or Phosphamidon 0.05% and destruction of affected plants and collateral hosts. Harvesting to be done at least 10 days after insecticide or fungicide application (KAU,1996).... cucurbits

Adenanthera Pavonina

Linn.

Adansonia digitata Linn.

Family: Bombacaceae.

Habitat: Native to tropical Africa; common along the west coast of India.

English: Baobab, Monkey Bread tree, African calabash.

Ayurvedic: Sheet-phala, Ravanaam- likaa, Gorakshi, Panchparni.

Unani: Gorakh Imli.

Siddha/Tamil: Papparapuli.

Folk: Gorakh Imli; Gorakh Chinchaa.

Action: Cooling, refrigerant (allays burning sensation). Leaves— diaphoretic (used as a prophylactic against fevers). Fruit—antidysen- teric, antiseptic, antihistaminic.

The fruit pulp is a source of vitamin C (175.0-445.4 mg/100 g); dried pulp contains calcium and vitamin B1. Furfural (9.6%) is obtained after distillation of the fruit. In Africa, dried leaves provide much of the dietary calcium. Aqueous extract of the bark is used for treating sickle cell anaemia.

An infusion of the leaves and flowers is given in respiratory disorders. (Powdered leaves prevented crisis in asthma induced by histamine in guinea pigs.) Dried fruit pulp also gives relief in bronchial asthma, allergic dermatitis and urticaria.

Family: Leguminosae; Mimosaceae.

Habitat: The western Ghats, the Andamans and sub-Himalayan tract; also cultivated.

English: Coral Wood, Red Wood.

Ayurvedic: Rakta Kanchana, Rakta Kambala.

Siddha/Tamil: Anai-gundumani.

Folk: Ghumchi (bigger var.).

Action: Astringent and styptic (used in diarrhoea, haemorrhage from the stomach, haematuria), anti-inflammatory (in rheumatic affections, gout). Seeds— anticephalgic; also used for the treatment of paralysis. A decoction is given in pulmonary affections.

The seed contains an anti-inflammatory active principle, O-acetyletha- nolamine. The leaves contain octa- cosanol, dulcitol, glucosides of beta- sitosterol and stigmasterol. The bark contains sitgmasterol glucoside.... adenanthera pavonina

Aerva Javanica

(Burm. f.) Juss. ex Schult.

Synonym: A. persica (Burm.f.) Merill

A. tomentosa Frosk

Family: Amaranthaceae.

Habitat: Punjab, Central and Peninsular India.

English: Javanese Wool Plant.

Siddha/Tamil: Perumpoolai.

Folk: Dholphuli, Khul. Paashaanab- heda (southern India).

Action: Anti-inflammatory, diuretic, anticalculus, insecticidal. Wooly seeds are used against rheumatism.

The plant extract contains ascorbic acid, kaempferol, beta-amyrin and beta-sitosterol. The leaves also contain sitosterol and its glucoside.... aerva javanica

Agrimonia Eupatoria

auct non L.

Synonym: A. pilosa Hook.f. non Ledeb.

A. pilosa Ledeb. var. nepalensis (D. Don) Nakai

Family: Rosacae.

Habitat: The Himalayas from Kashmir to West Bengal at 9003,000 m, and in Arunachal Pradesh, Nagaland and Meghalaya.

English: Agrimony, Stickle Wort.

Unani: Ghaafis.

Folk: Belu.

Action: Astringent, anti- inflammatory, hepatic, cholagogue, diuretic, mild haemostatic, antibacterial. Used for irritations and infections of the intestinal tract, gallbladder diseases, hyperacidity, colic, urinary disorders (bed- wetting, incontinence), sluggish liver, mucus membrane inflammations; externally for ulcerated and discharging skin, psoriasis and seborrhoic eczemas.

Key application: In mild, nonspecific, acute diarrhoea and in inflammation of oral and pharyngeal mucosa; as astringent. (German Commission E, The British Herbal Pharmacopoeia.)

The herb contains condensed tannins up to 8%, coumarins, flavonoids (glucosides of luteolin, apigenin and quercetin), polysaccharides, volatile oil. Luteolin 7-glucoside shows a chole- gogic action. Aqueous extracts inhibited Mycobacterium tuberculosis, also strains resistant to streptomycin and p-aminosalicylate. Essential oil is antibacterial, active against Bacillus sub- tilis.

The ethanolic extracts of the herb are used for their antiviral properties. (Natural Medicines Comprehensive Database, 2007.)

Coumarins interact with anticoagulants, and drugs that increase the risk of bleeding Furanocoumarin content increase photosensitivity. (Sharon M. Herr.)... agrimonia eupatoria

Gnida Glauca

(Fresen.) Gilg.

Synonym: G. eriocephalus Meis. Lasiosiphon glaucus Fresen. L. eriocephalus (Meisner) Decne.

Habitat: Western Ghats.

Action: Leaf—anti-inflammatory; used for contusions and swellings. Plant—vesicant.

The plant contains bicoumarins, lysocephalin and lasiocrin; a coumarin glucoside, crioside, and a bicoumarin glycoside, eriocephaloside. The plant also gave ingiresinol, syringin, gen- kwanin and its glycoside, beta-sitos- terol and its glucoside.... gnida glauca

Indian Bdellium

Commiphora mukul

Burseraceae

San: Gugulu, Mahisaksah, Koushikaha, Devadhupa

Hin: Gugal Mal:Gulgulu Tam,

Tel: Gukkulu

Kan: Guggul

Ben: Guggul

Importance: Indian bdellium is a small, armed, deciduous tree from the bark of which gets an aromatic gum resin, the ‘Guggul’ of commerce. It is a versatile indigenous drug claimed by ayurvedists to be highly effective in the treatment of rheumatism, obesity, neurological and urinary disorders, tonsillitis, arthritis and a few other diseases. The fumes from burning guggul are recommended in hay- fever, chronic bronchitis and phytises.

The price of guggulu gum has increased ten fold in ten years or so, indicating the increase in its use as well as decrease in natural plant stand. It has been listed as a threatened plant by Botanical Survey of India (Dalal, 1995) and is included in the Red Data Book (IUCN) and over exploited species in the country (Billare,1989).

Distribution: The center of origin of Commiphora spp. is believed to be Africa and Asia. It is a widely adapted plant well distributed in arid regions of Africa (Somalia, Kenya and Ethiopia in north east and Madagascar, Zimbabwe, Botswana, Zaire in south west Africa), Arabian peninsula (Yemen, Saudi Arabia and Oman). Different species of Commiphora are distributed in Rajasthan, Gujarat, Maharashtra and Karnataka states of India and Sind and Baluchistan provinces of Pakistan (Tajuddin et al, 1994). In India, the main commercial source of gum guggul is Rajasthan and Gujarat.

Botany: The genus Commiphora of family Burseraceae comprises about 185 species. Most of them occur in Africa, Saudi Arabia and adjoining countries. In India only four species have been reported. They are C. mukul(Hook. ex Stocks) Engl. syn. Balsamodendron mukul (Hook. ex Stocks), C. wightii (Arnott) Bhandari, C.stocksiana Engl., C. berryi and C.agallocha Engl.

In early studies about the flora of India, the ‘guggul’ plant was known as Commiphora mukul(Hook. ex Stocks) Engl. or Balsamodendron mukul (Hook. ex Stocks). It was renamed as C. roxburghii by Santapau in 1962. According to Bhandari the correct Latin name of the species is C. wightii(Arnott) Bhandari, since the specific name ‘wightii’ was published in 1839, prior to ‘roxburghi’ in 1848 (Dalal and Patel, 1995).

C. mukul is a small tree upto 3-4m height with spinescent branching. Stem is brownish or pale yellow with ash colored bark peeling off in flakes. Young parts are glandular and pubescent. Leaves are alternate, 1-3 foliate, obovate, leathery and serrate (sometimes only towards the apex). Lateral leaflets when present only less than half the size of the terminal ones. Flowers small, brownish red, with short pedicel seen in fascicles of 2-3. Calyx campanulate, glandular, hairy and 4-5 lobed. Corolla with brownish red, broadly linear petals reflexed at apex. Stamens 8-10, alternatively long and short. Ovary oblong, ovoid and stigma bifid. Fruit is a drupe and red when ripe, ovate in shape with 2-3 celled stones. The chromosome number 2n= 26 (Warrier et al, 1994; Tajuddin et al, 1994).

Agrotechnology: Guggal being a plant of arid zone thrives well in arid- subtropical to tropical climate.

The rainfall may average between 100mm and 500mm while air temperature may vary between 40 C in summer and 3 C during winter. Maximum relative humidity prevails during rainy season (83% in the morning and 48% in the evening).Wind velocity remains between 20-25 km/hour during the year is good. Though they prefer hard gypseous soil, they are found over sandy to silt loam soils, poor in organic matter but rich in several other minerals in arid tracks of western India (Tajuddin et al, 1994).

Plants are propagated both by vegetatively and seeds. Plants are best raised from stem cuttings from the semi woody (old) branch. For this purpose one metre long woody stem of 10mm thickness is selected and the cut end is treated with IBA or NAA and planted in a well manured nursery bed during June-July months; the beds should be given light irrigation periodically. The cuttings initiate sprouting in 10-15 days and grow into good green sprout in 10-12 months. These rooted plants are suitable for planting in the fields during the next rainy season. The cuttings give 80-94% sprouting usually. Air layering has also been successfully attempted and protocol for meristem culture is available in literature. Seed germination is very poor (5%) but seedling produce healthier plants which withstand high velocity winds.

The rooted cuttings are planted in a well laid-out fields during rainy season. Pits of size 0.5m cube are dug out at 3-4 m spacing in rows and given FYM and filler soil of the pit is treated with BHC (10%) or aldrin (5%) to protect the new plants from white ants damage. Fertilizer trials have shown little response except due to low level of N fertilization. Removal of side branches and low level of irrigation supports a good growth of these plants. The plantation does not require much weeding and hoeing. But the soil around the bushes be pulverised twice in a year to increase their growth and given urea or ammonium sulphate at 25- 50g per bush at a time and irrigated. Dalal et al (1989) reported that cercospora leaf spot was noticed on all the cultures. Bacterial leaf blight was also noticed to attack the cultures. A leaf eating caterpillar (Euproctis lanata Walker) attack guggal, though not seriously. White fly (Bemisia tabaci) is observed to suck sap of leaves and such leaves become yellowish and eventually drop. These can be effectively controlled by using suitable insecticide.

Stem or branch having maximum diameter of about 5cm at place of incision, irrespective of age is tapped. The necrotic patch on the bark is peeled off with a sharp knife and Bordeaux paste is applied to the exposed (peeled off) surface of the stem or branch. A prick chisel of about 3cm width is used to make bark- deep incisions and while incising the bark, the chisel is held at an acute angle so that scooped suspension present on the body of the chisel flows towards the blade of the chisel and a small quantity of suspension flows inside the incised bark. If tapping is successful, gum exudation ensures after about 15-20 days from the date of incision and continues for nearly 30-45 days. The exuded gum slides down the stem or branch, and eventually drops on the ground and gets soiled. A piece of polythene sheet can be pouched around the place of incision to collect gum. Alternatively, a polythene sheet can be spread on the ground to collect exuded gum. A maximum of about 500g of gum has been obtained from a plant (Dalal, 1995).

Post harvest technology: The best grade of guggul is collected from thick branches of tree. These lumps of guggul are translucent. Second grade guggul is usually mixed with bark, sand and is dull coloured guggul. Third grade guggul is usually collected from the ground which is mixed with sand, stones and other foreign matter. The final grading is done after getting cleansed material. Inferior grades are improved by sprinkling castor oil over the heaps of the guggul which impart it a shining appearance (Tajuddin et al, 1994).

Properties and activity: The gum resin contains guggul sterons Z and E, guggul sterols I-V, two diterpenoids- a terpene hydrocarbon named cembreneA and a diterpene alcohol- mukulol, -camphrone and cembrene, long chain aliphatic tetrols- octadecan-1,2,3,4-tetrol, eicosan-1,2,3,4-tetrol and nonadecan-1,2,3,4-tetrol. Major components from essential oil of gum resin are myrcene and dimyrcene. Plant without leaves, flowers and fruits contains myricyl alcohol, -sitosterol and fifteen aminoacids. Flowers contain quercetin and its glycosides as major flavonoid components, other constituents being ellagic acid and pelargonidin glucoside (Patil et al, 1972; Purushothaman and Chandrasekharan, 1976).

The gum resin is bitter, acrid, astringent, thermogenic, aromatic, expectorant, digestive, anthelmintic, antiinflammatory, anodyne, antiseptic, demulcent, carminative, emmenagogue, haematinic, diuretic, lithontriptic, rejuvenating and general tonic. Guggulipid is hypocholesteremic (Husain et al, 1992; Warrier et al, 1994).... indian bdellium

Justicia Procumbens

Linn.

Family: Acanthaceae.

Habitat: Western Ghats, West Coast from Konkan to Kerala; abundant in the rainy season.

Ayurvedic: Parpata (substitute).

Action: The plant contains naphthofuranones, justicidin A, B, C, D, G and H, and diphyllin, which are used for the treatment of osteoporosis. The flowers contain peonidine glucoside. Essential oil— antifungal.... justicia procumbens

Agropyron Repens

Beauv.

Synonym: Triticum repens L.

Family: Gramineae; Poaceae.

Habitat: The western Himalayas and Kashmir at altitudes between 2,700 and 3,600 m.

English: Couch grass, dog grass, wheat grass.

Action: Demulcent (used in cystitis, nephritis), aperient, diuretic and urinary antiseptic, anticholesterolaemic.

Key application: In irrigation therapy for inflammatory diseases of the urinary tract and for the prevention of kidney gravel. (German Commission E, The British Herbal Pharmacopoeia.) It is contraindicated in oedema due to cardiac or renal insufficiency.

The juice of rhizomes is used for cystitis, nephritis, scirrhous liver; decoction for tonsils and as an adjuvant for cancer; also used for gout and rheumatism, and chronic skin disorders.

The rhizome contains triticin, a carbohydrate allied to starch, a fruc- tosan polysaccharide, inositol, manni- tol; volatile oil up to about 0.05%, consisting mainly of agropyrene; vanillin glucoside; mucilage, gum, large quantities of silica; iron, minerals, vitamins, K salt. Agropyrene is reported to have broad antibiotic properties. Extracts show uric acid solvent properties. Agropyrene is antifungal.... agropyron repens

Althaea Officinalis

Linn.

Family: Malvaceae.

Habitat: Native to eastern Europe; found in Kashmir and Himachal Pradesh.

English: Marshmallow, Hollyhock.

Unani: Khatmi, Gul-Khairu (also equated with Althaea rosea Linn.).

Siddha/Tamil: Shemai-tutti.

Action: Demulcent, emollient, antitussive (used for cough, bronchitis, gastritis, enteritis and cystitis), antilithic, diuretic.

Key application: (leaf and root) In irritation ofthe oral and pharyngeal mucosa and associated dry cough; in mild inflammation of the gastric mucosa. (German Commission E, ESCOP.) As demulcent. (The British Herbal Pharmacopoeia.) In gastroenteritis, peptic and duodenal ulceration, common and ulcerative colitis. (The British Herbal Compendium.) Topically for varicose veins, skin ulcers, abscesses, cuts, burns.

Althaea rosea (L.) Cav., synonym Al- cea rosea L., Hollyhock flower, is used as mucilage for prophylaxis and therapy of diseases and discomforts of the respiratory and gastrointestinal tract and for urinary complaints. (It is included among unapproved herbs by German Commission E.)

The root contains starch, mucilage, pectin, flavonoids, phenolic acids, sucrose, tannins and asparagines. Mucilage (18-35%) consists of a number of polysaccharides. Flavonoids include kaempferol, quercetin and diosmetin glucosides. Polyphenolic acids include syringic, caffeic, salcyclic, vanillic and p-coumaric acids.

The mucilages have proven biological activity including stimulation of phagocytosis in vitro.

The root counters excess stomach acid, peptic ulceration and gastritis.... althaea officinalis

Anisochilus Carnosus

Wall.

Family: Labiatae; Lamiaceae.

Habitat: The western Himalayas, Central and southern India.

Folk: Karpuravalli (southern region).

Action: Stimulant, expectorant and diaphoretic. Juice of fresh leaves is used in urticaria and other allergic conditions; a domestic remedy for coughs and cold. Alcoholic extract of the whole plant—antibacterial. Essential oil—antitubercular.

The oil exhibits antihistaminic property in vitro on smooth muscles of the uterus and the intestines. It also possesses muscle-relaxant action; bactericidal and fungicidal properties. The leaves contain glucosides of luteolin and apigenin.... anisochilus carnosus

Arctostaphylos Uva-ursi

Spreng.

Family: Ericaceae.

Habitat: Native to North America, Europe and Asia.

English: Bearberry.

Unani: Inbud-dub, Angur-e-khiras, Reechh Daakh.

Action: Astringent, dirutic; used for urinary tract infections, dysuria, cystitis, urethritis, pyelitis.

The leaves gave 0.8-1% of a flavanol glucoside, isoquercitin, arbutin and methyl arbutin. Total arbutin content varies from 7.5 to 10.7%; tannins 15 to 20%. Arbutin hydrolyses to hydro- quinone, a urinary antiseptic.

Arbutin is antimicrobial, but the crude extract of uva-ursi is more effective than isolated arbutin. In rats, uva- ursi showed anti-inflammatory activity against experimentally induced inflammation. (Natural Medicines comprehensive Database, 2007.)... arctostaphylos uva-ursi

Medicinal Yams

Dioscorea spp.

Dioscoreaceae

The growing need for steroidal drugs and the high cost of obtaining them from animal sources led to a widespread search for plant sources of steroidal sapogenins, which ultimately led to the most promising one. It is the largest genus of the family constituted by 600 species of predominantly twining herbs. Among the twining species, some species twine clockwise while others anti-clockwise (Miege, 1958). All the species are dioceous and rhizomatous. According to Coursey (1967), this genus is named in honour of the Greek physician Pedenios Dioscorides, the author of the classical Materia Medica Libri Quinque. Some of the species like D. alata and D. esculenta have been under cultivation for a long time for their edible tubers. There are about 15 species of this genus containing diosgenin. Some of them are the following (Chopra et al, 1980).

D. floribunda Mart. & Gal.

D. composita Hemsl; syn. D. macrostachya Benth.

D. deltoidea Wall. ex Griseb; syn. D. nepalensis Sweet ex Bernardi.

D. aculeata Linn. syn. D. esculenta

D. alata Linn. syn. D. atropurpurea Roxb.

D. Globosa Roxb; D. purpurea Roxb; D. rubella Roxb.

D. bulbifera Linn. syn. D. crispata Roxb.

D. pulchella Roxb.; D. sativa Thunb. Non Linn.

D. versicolor Buch. Ham. Ex Wall.

D. daemona Roxb. syn. D. hispida Dennst.

D. oppositifolia Linn.

D. pentaphylla Linn. syn. D. jacquemontii Hook. f.

D. triphylla Linn.

D. prazeri Prain & Burkil syn. D. clarkei Prain & Burkill

D. deltoidea Wall. var. sikkimensis Prain

D. sikkimensis Prain & Burkill

Among the above said species, D. floribunda, D. composita and D. deltoidea are widely grown for diosgenin production.

1. D. floribunda Mart. & Gal D. floribunda Mart. & Gal. is an introduction from central America and had wide adaptation as it is successfully grown in Karnataka, Assam, Meghalaya, Andaman and Goa. The vines are glabrous and left twining. The alternate leaves are borne on slender stems and have broadly ovate or triangular ovate, shallowly cordate, coriaceous lamina with 9 nerves. The petioles are 5-7cm long, thick and firm. Variegation in leaves occurs in varying degrees. The male flowers are solitary and rarely in pairs. Female flowers have divericate stigma which is bifid at apex. The capsule is obovate and seed is winged all round. The tubers are thick with yellow coloured flesh, branched and growing upto a depth of 30cm (Chadha et al, 1995).

2. D. composita Hemsl.

D. composita Hemsl. according to Knuth (1965) has the valid botanical name as D. macrostachya Benth. However, D. composita is widely used in published literature. It is a Central American introduction into Goa, Jammu, Bangalore, Anaimalai Hills of Tami Nadu and Darjeeling in W. Bengal. The vines are right twinning and nearly glabrous. The alternate leaves have long petioles, membraneous or coriaceous lamina measuring upto 20x18cm, abruptly acute or cuspidate-acuminate, shallowly or deeply cordate, 7-9 nerved. The fasciculate-glomerate inflorescence is single or branched with 2 or 3 sessile male flowers having fertile stamens. Male fascicle is 15-30cm long. The female flowers have bifid stigma. Tubers are large, white and deep-rooted (upto 45cm) (Chadha et al, 1995).

3. D. deltoidea Wall. ex. Griseb.

D. deltoidea Wall. ex. Griseb. is distributed throughout the Himalayas at altitudes of 1000-3000m extending over the states of Jammu-Kashmir, H. P, U. P, Sikkim and further into parts of W. Bengal. The glabrous and left twining stem bears alternate petiolate leaves. The petioles are 5-12 cm long. The lamina is 5-15cm long and 4-12cm wide widely cordate. The flowers are borne on axillary spikes, male spikes 8-40cm long and stamens 6. Female spikes are 15cm long, 3. 5cm broad and 4-6 seeded. Seeds are winged all round. Rhizomes are lodged in soil, superficial, horizontal, tuberous, digitate and chestnut brown in colour (Chadha et al, 1995). D. deltoidea tuber grows parallel to ground covered by small scale leaves and is described as rhizome. The tubers are morphologically cauline in structure with a ring of vascular bundles in young tubers which appear scattered in mature tubers (Purnima and Srivastava, 1988). Visible buds are present unlike in D. floribunda and D. composita where the buds are confined to the crown position (Selvaraj et al, 1972).

Importance of Diosgenin: Diosgenin is the most important sapogenin used as a starting material for synthesis of a number of steroidal drugs. For commercial purposes, its -isomer, yamogenin is also taken as diosgenin while analysing the sample for processing. Various steroidal drugs derived from diosgenin by artificial synthesis include corticosteroids, sex hormones, anabolic steroids and oral contraceptives. Corticosteroids are the most important group of steroidal drugs synthesized from diosgenin. First group of corticosteroids regulates carbohydrate and protein metabolism. The second group consists of aldosterone, which controls balance of potassium, sodium and water in the human body. The glucocorticoids in the form of cortisone and hydrocortisone are used orally, intramuscularly or topically for treatment of rheumatoid arthritis, rheumatic fever, other collegen diseases, ulcerative colitis, certain cases of asthma and a number of allergic diseases affecting skin, eye and the ear. These are also used for treatment of gout and a variety of inflammations of skin, eye and ear and as replacement therapy in Addison’s diseases. The minerato corticoides, desoxycorticosterone or desoxycortone are used in restoring kidney functions in cases of cortical deficiency and Addison’s disease.

Both male and female sex hormones are also synthesized from disosgenin. The main male sex hormone (androgen) which is produced from disogenin is testosterone. The main female sex hormones produced are oestrogen and progesterone. Recently oestrogen has also been used in cosmetic lotions and creams to improve the tone and colour of skin. One of the main uses of progesterone during recent years has been as antifertility agent for oral contraceptives. These artificial steroids have increased oral activity and fewer side effects, as they can be used in reduced doses. Oral contraceptives are also used for animals like pigs, cows and sheep to control fertility and to give birth at a prescribed period in a group of animals at the same time. These compounds are also used to reduce the interval between the lactation periods to have more milk and meat production. Anti-fertility compounds are also used as a pest-control measure for decreasing the multiplication of pests like rodents, pigeons and sea gulls (Husain et al, 1979).

Although yam tubers contain a variety of chemical substances including carbohydrates, proteins, alkaloids and tannins, the most important constituents of these yams are a group of saponins which yield sapogenins on hydrolysis. The most imp ortant sapogenin found in Dioscorea are diosgenin, yamogenin and pannogenin. Diosgenin is a steroid drug precursor. The diogenin content varies from 2-7% depending on the age of the tubers. Saponins including 5 spirastanol glucoside and 2 furostanol glucoside, 4 new steroid saponins, floribunda saponins C, D, E and F. Strain of A and B are obtained from D. floribunda (Husain et al, 1979). Rhizomes of D. deltoidea are a rich source of diosgenin and its glycoside. Epismilagenin and smilagenone have been isolated from D. deltoidea and D. prazeri (Chakravarti et al, 1960; 1962). An alkaloid dioscorine has been known to occur in D. hispida (Bhide et al,1978). Saponin of D. prazeri produced a fall of blood pressure when given intravenously and saponin of D. deltoidea has no effect on blood pressure (Chakravarti et al,1963). Deltonin, a steroidal glycoside, isolated from rhizomes of D. deltoidea showed contraceptive activity (Biokova et al, 1990).

Agrotechnology: Dioscorea species prefer a tropical climate without extremity in temperature. It is adapted to moderate to heavy rainfall area. Dioscorea plants can be grown in a variety of soils, but light soil is good, as harvesting of tubers is easier in such soils. The ideal soil pH is 5.5-6.5 but tolerates fairly wide variation in soil pH. Dioscorea can be propagated by tuber pieces, single node stem cuttings or seed. Commercial planting is normally established by tuber pieces only. Propagation through seed progeny is variable and it may take longer time to obtain tuber yields. IIHR, Bangalore has released two improved varieties, FB(c) -1, a vigorously growing strain relatively free from diseases and Arka Upkar, a high yielding clone. Three types of tuber pieces can be distinguished for propagation purpose, viz. (1) crown (2) median and (3) tip, of which crowns produce new shoots within 30 days and are therefore preferred. Dipping of tuber pieces for 5 minutes in 0.3% solution of Benlate followed by dusting the cut ends with 0.3% Benlate in talcum powder in mo ist sand beds effectively checks the tuber rot. The treatment is very essential for obtaining uniform stand of the crop. The best time of planting is the end of April so that new sprouts will grow vigorously during the rainy season commencing in June in India. Land is to be prepared thoroughly until a fine tilth is obtained. Deep furrows are made at 60cm distance with the help of a plough. The stored tuber pieces which are ready for planting is to be planted in furrows with 30cm between the plants for one year crop and 45cm between the plants for 2 year crop at about 0.5 cm below soil level. The new sprouts are to be staked immediately. After sprouting is complete, the plants are to be earthed up. Soil from the ridges may be used for earthing up so that the original furrows will become ridges and vice versa. Dioscorea requires high organic matter for good tuber formation. Besides a basal doze of 18-20t of FYM/ha, a complete fertilizer dose of 300kg N, 150kg P2O5 and K2O each are to be applied per hectare. P and K are to be applied in two equal doses one after the establishment of the crop during May-June and the other during vigorous growth period of the crop (August- September). Irrigation may be given at weekly intervals in the initial stage and afterwards at about 10 days interval. Dioscorea vines need support for their optimum growth and hence the vines are to be trailed over pandal system or trellis. Periodic hand weeding is essential for the first few months. Intercropping with legumes has been found to smother weeds and provide extra income. The major pests of Dioscorea are the aphids and red spider mites. Aphids occur more commonly on young seedlings and vines. Young leaves and vine tips eventually die if aphids are not controlled. Red spider mites attack the underside of the leaves at the base near the petiole. Severe infestations result in necrotic areas, which are often attacked by fungi. Both aphids and spider mites can be very easily controlled by Kelthane. No serious disease is reported to infect this crop. The tubers grow to about 25-30 cm depth and hence harvesting is to be done by manual labour. The best season for harvesting is Feb-March, coinciding with the dry period. On an average 50-60t/ha of fresh tubers can be obtained in 2 years duration. Diosgenin content tends to increase with age, 2.5% in first year and 3-3.5% in the second year. Hence, 2 year crop is economical (Kumar et al, 1997).... medicinal yams

Microglossa Pyrifolia

(Lamk.) Kuntze.

Synonym: M. volubilis DC.

Family: Asteraceae, Compositae.

Habitat: North-eastern Indian hills.

Action: Leaf—used for ringworm of the scalp.

A acetylenic glucoside, isolated from the leaf, showed antibacterial activity against Pseudomonas aeruginosa and Staphylococcus aureus.... microglossa pyrifolia

Paris Polyphylla

Sm.

Family: Liliaceae.

Habitat: Temperate Himalayas from Simla to Bhutan and in Lushai and Aka Hills. Haimavati, Shveta-

Action: Plant—sedative, analgesic, haemostatic, anthelmintic.

The rhizome contains a glucoside, alpha-paristyphnin, which exhibited a depressant action on carotid pressure, myocardium, and respiratory movements experimentally. It produced vasoconstriction in kidney, but vasodilation in the spleen and limbs, and stimulated isolated intestines.... paris polyphylla

Ambrette

Abelmoschus moschatus

Malvaceae

San: Latakasturika Hin, Guj,

Ben: Mushkdana Mal: Kasthurivenda Mar: Kasthuri- bhendi

Tel: Kasturi benda

Tam: Varttilaikasturi

Kan: Kasturi bende Ass: Gorukhiakorai

Importance: Ambrette, also popularly known as musk or Muskmallow, is an erect annual herb which yields musk-like scented seeds and woos everybody through its sensuous musky fragrance. Every part of this medicinal plant is used in one or the other way. Seeds are effective aphrodisiac and antispasmodic, and used in tonics. They check vomiting and cure diseases due to kapha and vata and are useful in treating intestinal disorders, urinary discharge, nervous disorders, hysteria, skin diseases, snake bites, pruritus, leucoderma and general debility. Flower infusion is contraceptive. The leaves and roots are used for gonorrhoea and to treat boils and swellings.

Ambrette oil of commerce is extracted from the seeds and is used in perfumery, flavouring, cosmetic and agarbathi industries. The essential oil is employed in non-alcoholic beverages, ice-creams, candies and baked foods. The aromatic concrete and absolute, extracted from seeds are used as base material for preparing high grade perfumes, scents and cosmetics. It is also known for exalting, amplifying and diffusing effects it imparts to perfumes. It blends well with rose, neroli, and sandal wood oil and aliphatic aldehydes.

The flowers are in great demand for making ‘zarda’ a flavoured tobacco in India. The seeds are mixed with tea and coffee for flavour. The seed is rich in essential amino acids and is used as cattle or poultry feed. The stem bark yields a good quality fibre. Seeds are used to protect woollen garments against moth and it imparts a musky odour to sachets, hair powder, panmasala and incense. Its tender shoots are used in soups, green pods as vegetable and seed husk in flower arrangements. From perfumes to panmasalas and tonics, it is the musky musk all the way. In addition to internal consumption, its seeds are exported to Canada, France and UK because of its diversified uses (Srinivasan et al, 1997).

Distribution: The musk plant is a native of India and it grows in the tropical subtropical and hilly regions of the country; particularly in the states of Maharashta, Gujarat, Madhyapresh, Tamil Nadu and Kerala. More than 50 collections of the plant are maintained by the National Bureau of Plant Genetic Resources (NBPGR), New Delhi and its regional station in Akola, Maharashtra.

Botany: Abelmoschus moschatus Medicus syn. Hibiscus abelmoshus Linn. belongs to Family Malvaceae. Muskmallow is an erect annual or biennial hirsute or hispid herb of 60-180 cm height. The leaves are simple polymorphous, usually palmately 3-7 lobed; lobes narrow, acute or oblong-ovate, crenate, serrate or irregularly toothed, hairy on both surfaces. Flowers are large and bright yellow with purple centre. Fruits are fulvous, hairy and capsular. Seeds are many, subreniform, black or greyish - brown and musk scented (Husain et al, 1992).

Agrotechnology: Ambrette is a hardy plant which can be grown in varied climate under tropical and subtropical conditions. It can be grown both as a rainfed crop and as an irrigated crop. It grows on well drained loamy and sandy loam soils. Loamy soils with neutral pH and plenty of organic matter are ideal for its cultivation.

Musk of propagated through seeds. The optimum time of sowing is June-July with pre- monsoon showers. The land is prepared well by ploughing, harrowing and levelling. Well decomposed FYM or compost is incorporated into the soil at 10 - 15 t/ha. Ridges and furrows are formed giving a spacing of 60 - 100 cm. Seed rate is 2-3 kg/ha. Seeds are soaked in water before sowing for 24 hours. Two to three seeds are sown per hole at 60 cm spacing on one side of the ridge at a depth of 1 cm and covered with a pinch of sand or loose soil. It takes 5-7 days for proper germination. After germination, extra seedlings are thinned out leaving one healthy growing plant per hole within 20 days. Fertilisers are applied at 120:40:40 kg N, P2O5, K2O/ha generally. However, a dose 160:80:80 kg/ha is recommended for best yields of seed and oil. Phosphorus is applied fully as basal. N and K are applied in 3 equal doses at planting, 2 and 4 months after planting. Fertilizers are applied 10 cm away from the plants. For irrigated crop, field is irrigated soon after sowing. Irrigation is given twice a week during the initial period and once a week thereafter. The field is kept weed free by regular weeding during the growing period (Farooqi and Khan, 1991).

Musk plants suffer from pests like spider mites, fruit bores and leaf eating caterpillars. Diseases like powdery mildew and wilt are also observed on the plant. Spider mites and powdery mildew are controlled by spraying 30g wettable sulphur in 10 litres of water. Pod borers can be controlled by spraying 20ml oxydemeton methyl in 10 litres of water.

The crop starts flowering about 75 days after sowing. The flowers set into fruits in 3-4 days and the pods take nearly a month to mature. Flowering and fruit setting extends from October to April. Harvesting is arduous. Fruits have to be plucked as soon as they attain black colour; otherwise, they split and seeds scatter. Therefore, weekly collection of pods is necessary and in all 20-25 pluckings may be required as it is a 170-180 days duration crop. The fruits are further dried and threshed to separate seeds. The seed yield is 1-1.5 /ha

Postharvest technology:. The oil is extracted from seed by steam distillation followed by solvent extraction.

The concrete of solvent extraction is further extracted with alcohol to get the absolute, that is, the alcohol soluble volatile concentrate.

Properties and activity: The fatty oil of seeds contain phospholipids as 2 - cephalin, phosphatidylserine and its plasmalogen and phosphatidyl choline plasmalogen. Absolute contains farnesol and ambrettolic acid lactone. - sitosterol and its - d - glucosides are isolated from leaves. Petals contain -sitosterol, flavonoid myricetin and its glucoside. Anthocyanins like cyanidin - 3 - sambubioside and cyanidin - 3 - glucoside are present in the flowers. (Chopra and Nayar, 1980) Seeds are aphrodisiac, antispasmodic, diuretic, demulcent, antiseptic, stomachic, tonic, carminative, antihysteric, antidiarrhoeal, ophthalmic, cardiac and antivenum.... ambrette

Piper Schmidtii

Hook. f.

Family: Piperaceae.

Habitat: Assam, Western Ghats, the Nilgiris and Palni hills above 1,500 m.

English: Nilgiri Pepper.

Action: Carminative.

The neolignan schmiditin, together with lignin galgravin as well as friedelin, beta-sitosterol and its beta- O-glucoside have been isolated from the extract of aerial parts. The extract exhibited antiamoebic activity.... piper schmidtii

Terminalia

Terminalia spp.

Combretaceae

The genus Terminalia includes a large group of medicinally valuable trees. They belong to the family Combretaceae.

The most important medicinal species of the genus Terminalia are the following.

1) T. arjuna (Roxb.ex DC) Wight & Arn.

San: Arjunah, Kakubhah;

Hin: Arjun, Kahu, Kahua;

Mal: Marutu, Nirmarutu, Venmarutu, Attumarutu, Pulamatti;

Tam: Attumarutu, Nirmarutu, Vellaimarutu, Marutu;

Kan: Maddi.

It is a large evergreen tree commonly found in Madhya Pradesh, Bihar and Peninsular and India. It has buttressed trunk and spreading crown with drooping branches. Bark is smooth, grey outside and flesh coloured inside, flaking off in large flat pieces. Leaves are simple, sub-opposite, oblong or elliptic, coriaceous, crenulate, pale dull green above, pale brown beneath, often unequal sided, nerves 10-15 pairs and reticulate. Flowers are white, arranged in panicles of spikes with linear bracteoles. Fruits are ovoid or oblong with 5-7 short, hard angles or wings, the lines on the wings oblique and curving upward (Warrier et al 1996).

The bark is useful in fractures, ulcers, urethrorrhoea, leucorrhoea, diabetes, vitiated conditions of pitta, anaemia, cardiopathy, fatigue, asthma, bronchitis, tumours, internal and external haemorrhages, cirrhosis of the lever and hypertension. It is used in fractures and the powdered bark is taken with milk. The bark powder is diuretic and has a general tonic effect in cases of cirrhosis of liver. The bark has been considered by the ayurvedic physicians as well as by modern practitioners as a cardiac tonic. It is given as a decoction with milk (NRF, 1998). In Ayurveda, “Arjunaghrita” and “Arjunarishta” are two important cardiotonic preparations of this drug.

Fruits contain flavanones - arjunone and 5,7,2’, 4’ - tetramethoxy flavone and a chalcone - cerasidin. Other constituents are -sitosterol, friedelin, methyloleanolate, gallic acid, ellagic acid and arjunic acid. Bark gave a triterpene arjungenin, triterpene glucosides I, II and III. Stem bark gave flavones - baicalein and arjunolone characterised as 6,4’ - dihydraxy - 7-methoxy flavone. Stem bark yields oxalic acid and tannins besides complex glycosides (Bhatra et al, 1980). Bark is alexertic, styptic, antidysenteric, astringent, antiasthmatic, febrifuge, expectorant, cardiotonic aphrodisiac and diuretic. Fruit is deobstruent. Stem-bark is CVS and CNS active, diuretic and abortifacient. Aerial part is CNS depressant and semen coagulant.

2) T. alata Heyne ex Roth. Syn. T. tomentosa (Roxb. Ex. Dc.) W & A.

San: Dharaphala, Saradru, Sajada;

Hin. Ain;

Ben: Asan, Paishal;

Mal: Tehmbara;

Tam: Karramarda, Karu Murutha, Marudam, Pudavam.

This tree is distributed in Himalaya from Kangra eastwords to Goalpara in Assam and southwards throughout the Peninsular India, upto 1200 m. The bark of the tree is widely used in ulcers, fractures, bronchitis and diarrhoea. Hydrolysis of the gum gives oligosaccharides, disaccharides and monosaccharides. Leaves and fruits give -sitosterol. Bark is diuretic, antihaemorrhagic, styptic, cardiotonic and semen coagulant.

3) T. bellirica (Craertn.) Roxb.

San: Aksha, Anilaghanaka, Baheduka, Harya, Kalinda;

Hin: Bulla, Sagona;

Ben: Bahera, Baheri;

Tam: Akkam, Kalanduri, Tani;

Tel: Bhutavasamu Tadi, Tandra, Vibhutakamu.

Belliric Myrobalan is distributed throughout India, upto 900 m. Its bark is used in anaemia and leucoderma. The fruit is used in bronchitis, strangury, sore throat, diseases of eye, nose, heart and bladder, hoarseness and piles. It forms an important constituent of the ayurvedic drug ‘triphala’. Furits contain -sitosterol, gallic and ellagic acids, ethyl gallate, galloyl glucose, chebulagic acid and a cardiac glucoside bellaricanin. Alcoholic extract of the fruit possesses bile-stimulating activity. Alcoholic extract, 30 mg/kg does not affect blood pressure and respiration, but a higher dose of 60 mg/kg produces a fall in blood pressure. Furit has anticancerous and flower has spermicidal activity. Bark is mild diuretic. Fruit is astringent, antidropsical, antileprotic, antiinflammatory, antidiarrhoeal, antibilious, stomachic, antiasthmatic, tonic, anticephalgic, bechic, anthelmintic and attenuant. Kernel is narcotic. Semi -ripe fruit is purgative. Gum is demulcent (Husain et al, 1992)

4) T. bialata steud.

White Chugalam or silver grey wood is a common tree of Andaman Islands. Its bark is used as a cardiac stimulant.

5) T. Catappa Linn.

San: Grahadruma;

Hin: Badam;

Ben: Bangla Badam:

Tam: Natuvdom, Vadhamkottai;

Tel: Vedam, Voda Movettilla; Mar: Jangli Badama, Nat Badam.

Indian Almond or Tropical Almond is a popular tree cultivated throughout the warmer parts of India including Andaman Islands and other adjacent island. Oil from the kernel is a substitute for almond oil. The leaf is used in scabies and colic. Husk and endocarp contain tannins and pentosans. Oil from kernel contains oleic, linoleic, palmitic and stearic acids. Heart wood and stem bark contains -sitosterol and its palmitate. Heartwood in addition contains terminolic acid and triterpenic methyl esters. The aerial part of the plant is diuretic. The bark is astringent, mild diuretic, cardiotonic and antidysenteric. Leaf is sudorific, antirheumatic, antileprotic and anticephalalgic.

6) T. Coriacea (Roxb.) syn. T. tomentosa (Roxb. ex. DC.) W. & A. var. coriacea (Roxb.) C. B. Clarke

Tam: Anaimikkuvam, Sadagam;

Kan: Banapu;

Tel: Tani.

Leathery Murdah is a tree commonly used as a cardiac stimulant. It is widely distributed in the drier and warmer parts of Andhra Pradesh and Tamil Nadu upto 1350 m and in Central India. Its bark is mainly used as a cardiac stimulant and in atonic diarrhoea and callous ulcer. It is also CVS active.

7) T. myriocarpa Heurck. & Muell. Arg.

Ben: Panisaj; Ass: Hollock, Jhalna.

Hollock is a tree of the Himalayas widely distributed from Nepal to Arunachal Pradesh and in Assam at 1000 m. The bark is cardiac stimulant and mild diuretic. Bark give -sitosterol, fructose and 4,4’,5,5’,6,6’ - hexadydroxy diphenic acid dilactone. Bark also contains tannis - ellagic, gallic, chebulinic and chebulagic acids.

8) T. Pallida Brandis.

Tam: Vellai Kadukkay;

Tel: Tella Karaka, Velama Karka.

The plant is distributed throughout south India, upto 600m. Its bark is a mild diuretic.

9) T. Paniculata Roth.

Mal: Marutu, Pe Marutu, Ven Marutu;

Tam: Pei Kadukai, Ven Maruthu, Ilai Kadukkay, Marudu, Pullatti;

Tel: Nimiri, Pulamaddi, Putamanu, Pulanallamanu;

Kan: Maruva, Matti.

Flowering Murdah is a tree which is widely used in opium poisoning. It is distributed in the Western and Eastern Ghats, upto 1200m. The bark is used in parotitis and flowers in opium poisioning. Heart wood give 3, 3’-0-di-methylellagic acid and 3,4,3’0-trimethyl flavellagic acid, -sitosterol, an uncharacterized triterpene carboxylic acid; a glycoside -3,3’ di-0 - methyl ellagic acid - 4 - monoglucoside and 0 - penta methyl flavellogic acid. The stem bark is anticancerous, diuretic, cardiotonic CVS active and shows antagonism of amphetamine hyperactivity. Flower is anticholerin (Husain et al, 1992)

10) Terminalia chebula Retz. Syn. Myrobalanus chebula (Retz.) Gaertner

Eng: Chebulic myrobalan;

San,

Ben: Haritaki;

Hindi:Harara, Harir,

Har; Mal:Kadukka; Ass:Hilikha; Kan:Alale;

Mar:Habra,

Hirada;

Ori:Harida;

Guj: Hirdo;

Pun:Helela;

Tam:Amagola;

Tel: Karaka

Chebulic myrobalan is a medium deciduous tree, the fruit of which is a common constituent of “Triphala” capable of imparting youthful vitality and receptivity of mind and sense. It is a major constituent in the ayurvedic preparations like Abhayarishta, Abhaya modak, Haritaki khand, Triphaladi churnam and Agastya rasayanam. In allopathy it is used in astringent ointments. In unani system, it is used as a blood purifier. The pulp of the fruit is given in piles, chronic diarrhoea, dysentery, costiveness, flatulence, asthma, urinary disorders, vomiting, hiccup, intestinal worms, ascites and enlarged spleen and liver. Powder of the fruit is used in chronic ulcers and wounds, carious teeth and bleeding ulceration of the gums. The bark is a good cardiac tonic. The fruit is valuable for its tannins and dyes. The wood is used for building purposes, agricultural implements, plywood and match box industries. It is also grown as a shade tree.

The plant is found throughout India chiefly in deciduous forests, on dry slopes upto 900m especially in Bengal, Tamil Nadu, West coast and Western Ghats. The plant is also reported in Sri Lanka, Nepal and Burma.

Terminalia chebula Retz. syn. Myrobalanus chebula (Retz.) Gaertner comes under family Combretaceae. It is a medium sized deciduous tree with a cylindrical bole, rounded crown, spreading branches with dark brown bark and brownish gray heartwood. Leaves are simple, alternate or subopposite, ovate or elliptic ovate with short petioles bearing 2 glands below the blades. Flowers pale yellow or white in 4-10cm long axillary spikes. Calyx tube hairy pale yellow and 5 lobed; no petals. Stamens consist of 10 filaments subulate, anthers small; ovary inferior, 1-celled with 2-3 pendulous ovule. Fruit is a drupe, ovoid glossy, glabrous, faintly angled and yellow to orange brown in colour. Seeds are hard and pale yellow.

Kernel oil of Chebulic myrobalan contains 6 fatty acids viz. Palmitic, stearic, oleic, linoleic, arachidic and behenic acid. The fruits contain chebulinic acid, tannic acid, gallic acid, chebulin and tannin. Leaves contain terpenes and saponins and -sitosterol is present in the bark (Beri, 1970; Khalique and Nizamuddin, 1972; Miglani and Chawla, 1974). Fruits are astringent, purgative, tonic, carminative, alternative and antispasmodic. Flowers and fruits are antiviral and hypoglycaemic. Wood is oxytocic and hypothermic (Husain et al, 1992).

Agrotechnology: Terminalia species are, in general, subtropical trees. Young plants prefer shade while the matured plants tolerate light frost and drought. It grows well in hilly areas. This is propagated by seeds. Natural multiplication happens rarely due to the poor seeds germination. Seeds soaked in water for 48 hours before sowing in seedbeds which should be covered with straw after sowing. It is watered immediately. Usually it takes 3-5 months to germinate. It can be transferred to polybags at two-leaf stage. One-year-old seedlings are ready for transplanting. For transplanting, pits are made of 50cm cube at a spacing of 4m. Organic manure, added regularly, promotes growth. Irrigation is required during first year. Weeds should be removed regularly. This plant grows slowly. It fruits within 6-7 years. This is continued for many years. It is coppiced well. Fruits are collected immediately after falling down or covered with soil to protect it from pests. Fruits dried well in sun and used or stored. The hard seed coat is removed before sowing.... terminalia

Asclepias Curassavica

Linn.

Family: Aristolochiaceae.

Habitat: Indigenous to the northern parts of southern Europe, Central and East-Central Europe; cultivated in the United States. A related sp., Asarum himalaicum, synonym A. canadense, is reported from the eastern Himalayas.

English: Asarbacca, Hazelwort, Wild Nard.

Unani: Asaaroon, Subul-e-Barri, Naardeen-Barri.

Folk: Tagar Ganthodaa.

Action: Brain and nervine tonic, diuretic, deobstructant and anti- inflammatory; used in bronchial spasm and in preparations of cephalic snuffs.

The volatile oil (0.7-4%) consists of asarone up to 50%, asaraldehyde 2-3%, methyleugenol 15-20%, with bornyl acetate, terpenes and sesquiterpenes. Asarone and its beta-isomer is found to be carcinogenic in animals. The rhizome, in addition, contains caffeic acid derivatives and flavonoids.

A related sp., Asarum canadense L., indigenous to North America and China, contains a volatile oil (3.5-

Family: Asclepiadaceae.

Habitat: Naturalized in many parts of India as an ornamental.

English: Curassavian Swallow- Wort, West Indian Ipecacuanha, Blood-Flower.

Ayurvedic: Kaakanaasikaa (substitute).

Folk: Kaakatundi (Kashmir).

Action: Spasmogenic, cardiotonic, cytotoxic, antihaemorrhagic, styptic, antibacterial. Various plant parts, as also plant latex, are used against warts and cancer. Root—used as an astringent in piles. Leaves—juice, antidysenteric, also used against haemorrhages. Flowers—juice, styptic. Alcoholic extract of the plant—cardiotonic.

An alcoholic extract of the Indian plant has been reported to contain a number of cardenolides, including calactin, calotropin, calotropagenin, coroglaucigenin, uzarigenin, asclepin, its glucosides and uzarin. Asclepin, the chief active principle, is spasmogenic and a cardiac tonic, having longer duration of action than digoxin (96 h in cat, as opposed to the 72 h of digoxin). Calotropin exhibits cytotoxic activity.

Pleurisy root of the U.S. is equated with Asclepias tuberosa. It is used for cold, flu and bronchitis in Western herbal medicine.

Toxic principles of the herb include galitoxin and similar resins, and glu- cofrugoside (cardenolide). Toxicity is reduced by drying.... asclepias curassavica

Barbarea Vulgaris

R. Br.

Family: Brassicaceae, Cruciferae.

Habitat: Subalpine and temperate Himalayas, at altitudes of 1,8003,750 m.

English: Bitter Cress, Hedge Mustard, Yellow Rocket, Winter Cress.

Folk: Cress.

Action: Diuretic, anthelmintic, stomachic, antiscorbutic, (leaves are rich in vitamin C 130 mg/100 g). Pulverised herb is used as an agent for stimulating spermatogenesis.

The roots contain sinigrin; seeds contain a glucoside, glucobarbarin, and myrosin.

The protein and phosphorus contents of the plant decrease with the maturity, whereas the calcium contents increase (tender stems are eaten as a salad). The leaves and buds are a rich source of provitamin A (beta- carotene).... barbarea vulgaris

Barleria Prionitis

Linn.

Family: Acanthaceae.

Habitat: Throughout the hotter parts of India. Also, commonly grown as a hedge plant in gardens.

English: Common Yellow Nail Dye Plant.

Ayurvedic: Sahachara, Baana, Kurantaka, Kuranta, Koranda, Korandaka, Shairiya, Pita-saireyaka

(yellow-flowered var.). Also equated with Vajradanti.

Unani: Piyaabaansaa.

Siddha/Tamil: Chemmulli.

Folk: Piyaabaasaa, Jhinti, Kat- saraiyaa.

Action: Leaf—juicegiveninstomach disorders, urinary affections; mixed with honey and given to children with fever and catarrh; leaf juice is applied to lacerated soles of feet in the rainy season, mixed with coconut oil for pimples. Leaves and flowering tops—diuretic. Bark—diaphoretic and expectorant. Roots—paste is applied over boils and glandular swellings. Plant (Vajradanti)—antidontalgic, used for bleeding gums in Indian medicine. Ash, obtained from the whole plant, mixed with honey, is given in bronchial asthma.

The Ayurvedic Pharmacopoeia of India recommends oil extract of the plant for arresting greying of hair.

The leaves and flowering tops are diuretic, rich in potassium salts. Leaves and stems showed presence of iridoid glucosides, barlerin and acetylbarlerin. Flowers gave the flavonoid glycoside, scutellarein-7-neohesperidoside. The presence of beta-sitosterol is reported in the plant.

In the south, Nila Sahachara is equated with Ecbolium linneanun Kurz. (known as Nilaambari), and Shveta Sa- hachara with Justica betonica Linn.

Ecbolium linneanun plant is used for gout and dysuria; the root is prescribed for jaundice.

Dosage: Whole plant—50-100 g for decoction. (API Vol. III.)... barleria prionitis

Glycoside

n. a compound formed by replacing the hydroxyl (–OH) group of a sugar by another group. (If the sugar is glucose the compound is known as a glucoside.) Glycosides found in plants include some pharmacologically important products, such as the cardiac glycoside *digoxin, derived from the foxglove (Digitalis). Other plant glycosides are natural food toxins, present in cassava, almonds, and other plant products, and may yield hydrogen cyanide if the plant is not prepared properly before eating.... glycoside

Bauhinia Retusa

Roxb.

Synonym: B. semla Wunderlin.

Family: Caesalpiniaceae.

Habitat: Northwestern Himalayas up to 1500 m, also in Orissa, Madhya Pradesh and Andhra Pradesh.

Siddha: Nirpa (Telugu).

Folk: Semalaa, Kathmahuli. Gum— Thaur

Action: Gum—emmenagogue, diuretic. (Gum resembles Gum arabic; used as an external application for sores). Protein isolated from seeds—hypoglycaemic, hypoc- holesterolaemic in young, normal as well as alloxan-induced diabetic albino rats.

The bark contains quercetin-3-O- beta-D-glucoside and rutin.... bauhinia retusa

Bael

Aegle marmelos

Rutaceae

San: Bilva, Sriphal Hin, Ben, Ass: Bael Mal: Koovalam

Tam: Vilvam Mar,

Ben: Baela

Tel: Marendu, Bilvapondu

Guj: Bilviphal

Kan: Bilvapatra

Importance: Bael or Bengal quince is a deciduous sacred tree, associated with Gods having useful medicinal properties, especially as a cooling agent. This tree is popular in ‘Shiva’ and ‘Vishnu’ temples and it can be grown in every house. Its leaves are trifoliate symbolizing the ‘Thrimurthies’-Brahma, Vishnu, Shiva, with spear shaped leaflets resembling “Thrisoolam” the weapon of Lord Shiva. Many legends, stories and myths are associated with this tree. The leaflets are given to devotees as ‘prasadam’ in Shiva temples and as ‘Tulasi’ in Vishnu temples.

Every part of the tree is medicinal and useful. The roots are used in many Ayurvedic medicines for curing diabetes and leprosy. It is an ingredient of the ‘dasamoola’. The Bark is used to cure intestinal disorders. Leaves contain an alkaloid rutacin which is hypoglycaemic.

‘Two leaves before breakfast’ is said to keep diabetes under control. Leaves and fruits are useful in controlling diarrhoea and dysentery. Fruit pulp is used as ‘shampoo’ and cooling agent. It is also a rich source of carbohydrate, protein, fat, fibre, minerals and vitamin B and C. Fruit pulp is used to cure mouth ulcers as it is the richest natural source of riboflavin (1191 units/ 100 g). ‘Bael sharbat’ is prepared by mixing the fruit pulp with sugar, water and tamarind juice, which is very useful for stomach and intestinal disorders. The rind of the fruit is used for dyeing and tanning. The aromatic wood is used to make pestles in oil and sugar mills and also to make agricultural implements (Rajarajan, 1997).

Distribution: Bael tree is native to India and is found growing wild in Sub-Himalayan tracts from Jhelum eastwards to West Bengal, in central and south India. It is grown all over the country, especially in the premises of temples and houses.

Botany: Aegle marmelos (Linn.) Corr.ex Roxb. belongs to the citrus family Rutaceae. The golden coloured bael fruit resembles a golden apple and hence the generic name Aegle. The specific name marmelos is derived from marmelosin contained in the fruit (Nair, 1997). Aegle marmelos is a medium sized armed deciduous tree growing upto 8m in height with straight sharp axillary thorns and yellowish brown shallowly furrowed corky bark. Leaves are alternate, trifoliate and aromatic; leaflets ovate or ovate-lanceolate, crenate, pellucid- punctate, the laterals subsessile and the terminal long petioled. Flowers are greenish-white, sweet scented, borne on axillary panicles. Fruit is globose, woody berry with golden yellow rind when ripe. Seeds are numerous oblong, compressed and embedded in the orange brown sweet gummy pulp.

Agrotechnology: Bael comes up well in humid tropical and subtropical climate. It grows on a wide range of soils from sandy loam to clay loam. North Indian varieties are preferred to South Indian types for large scale cultivation. Twelve varieties are cultivated in North India for their fruits. Kacha, Ettawa, Seven Large, Mirsapuri and Deo Reo Large are varieties meant specially for ‘Sharbat’. The plant is propagated mainly by seeds and rarely by root cuttings. Seeds are freshly extracted from ripe fruits after removing the pulp and then dried in sun. Seeds are soaked in water for 6 hours and sown on seed beds which are covered with rotten straw and irrigated regularly. Seeds germinate within 15-20 days. One month old seedlings can be transplanted into polybags which can be planted in the field after 2 months. Budded or grafted plants as well as new saplings arising from injured roots can also be used for planting. Grafted plants start yielding from the 4th year while the trees raised from seeds bear fruits after 7-10 years. Planting is done in the main field with onset of monsoon in June-July at a spacing of 6-8m. Pits of size 50cm3 are dug. Pits are filled with a mixture of top soil and 10kg of well decomposed FYM and formed into a heap. Seedlings are transplanted in the middle of the heap and mulched. Chemical fertilisers are not usually applied. The dose of organic manure is increased every year till 50kg/tree of 5 years or more. Regular irrigation and weeding are required during early stages of growth. No serious pests and diseases are noted in the crop. Bael tree flowers during April. The flowers are aromatic with pleasant and heavenly odour. The fruits are set and slowly develop into mature fruits. Fruits are seen from October-March. A single tree bears 200-400 fruits each weighing 1-2 kg. Roots can be collected from mature trees of age 10 years or more. Tree is cut down about 1m from the ground. The underground roots are carefully dug out. Roots with the attached wood is then marketed (Rajarajan,1997).

Properties and activity: Bael is reported to contain a number of coumarins, alkaloids, sterols and essential oils. Roots and fruits contain coumarins such as scoparone, scopoletin, umbelliferone, marmesin and skimmin. Fruits, in addition, contain xanthotoxol, imperatorin and alloimperatorin and alkaloids like aegeline and marmeline identified as N-2-hydroxy-2- 4 - (3’,3’-dimethyl allyloxy) phenyl ethyl cinnamide. - sitosterol and its glycoside are also present in the fruits. Roots and stem barks contain a coumarin - aegelinol. Roots also contain psoralen, xanthotoxin, 6,7-dimethoxy coumarin, tembamide, mermin and skimmianine. Leaves contain the alkaloids - O-(3,3-dimethyl allyl)-halfordinol, N-2-ethoxy-2 (4-methoxy phenyl) ethyl cinnamide, N-2-methoxy-2-(4-3’,3’-dimethyl allyloxy) phenyl ethyl cinnamide, N- 2-4-(3’,3’-dimethyl allyloxy) phenyl ethyl cinnamide, N-2-hydroxy-2- 4-(3’,3’-dimethyl allyloxy) phenyl ethyl cinnamide, N-4-methoxy steryl cinnamide and N-2-hydroxy-2-(4- hydroxy phenyl) ethyl cinnamide. Mermesinin, rutin and -sitosterol - -D-glucoside are also present in the leaves (Husain et al, 1992).

Root, bark, leaves and fruits are hypoglycaemic, astringent and febrifuge. Root, stem and bark are antidiarrhoeal and antivenin. Leaf is antiinflammatory, expectorant, anticatarrhal, antiasthamatic, antiulcerous and ophthalmic. Flower is emetic. Unripe fruit is stomachic and demulcent. Ripe fruit is antigonorrhoeal, cardiotonic, restorative, laxative, antitubercular, antidysenteric and antiscorbutic. Seed is anthelmintic and antimicrobial (Warrier et al, 1993).... bael

Belamcanda Chinensis

(L.) DC.

Family: Iridaceae.

Habitat: Introduced from China; cultivated all over India, up to an altitude of 1,800 m.

Folk: Surajkaanti (Assam), Dasbaha, Dasbichandi (Bengal).

Action: Rhizomes—expectorant, deobstruent, resolvent, used in tonsillitis, chest and liver complaints (antiviral against pneumonia).

Presence of alkaloids is reported from the plant, glucoside, belamcan- din from the roots. The leaves and flowers contain a glycoflavone. The seeds tested positive for leucoantho- cyanins.... belamcanda chinensis

Blepharis Edulis

Pers.

Synonym: B. persica (Burm.f.) Kuntze.

Family: Acanthaceae.

Habitat: Punjab and western Rajasthan.

English: Acanthus.

Ayurvedic: Utangana, Kaamavridhi, Chatushpatri, Ucchataa (equated with Scirpus or Cyperus sp. during the classical period; with Shveta Gunjaa, Abrus sp. during the medieval period.)

Unani: Utangan.

Folk: Karadu (Maharashtra).

Action: Roots—diuretic. Used for urinary discharges and dys- menorrhoea. Seeds—deobstruent, resolvent, diuretic (used in strangury and sexual debility). Powdered plant is applied locally on infections of the genitals and on burns.

Key application: Seed in dysuria and impotency. (The Ayurvedic Pharmacopoeia of India.)

A benzoxazine glucoside, blephar- in, has been isolated from seeds, and a saponin, which on hydrolysis gave lupeol.

Dosage: Dried seed—3-6 g powder. (API Vol. IV.)... blepharis edulis

Bridelia Montana

Willd.

Family: Euphorbiaceae.

Habitat: The sub-Himalayan tract from Kashmir eastwards to Assam, and in Bihar, Orissa and Andhra Pradesh.

Ayurvedic: Ekaviraa.

Siddha/Tamil: Venge-maram.

Folk: Gondni, Asaanaa (Maharashtra).

Action: Bark and Root—astringent, anthelmintic. Used in the treatment of bone fracture.

The root contains 5.7% tannins.

The leaves contain beta-sitosterol, its beta-D-glucoside and a triterpe- noid. Fructose, glucose and sucrose were identified as the components of the glycoside.... bridelia montana

Butea Monosperma

(Lam.) Taub.

Synonym: B. frondosa Koenig ex Roxb.

Family: Papilionaceae; Fabaceae.

Habitat: Throughout India, up to 1,200 m except in very arid regions.

English: Flame of the Forest, Butea Gum, Bengal Kino.

Ayurvedic: Paalasha, Kimshuka, Raktapushpaka, Kshaarshreshtha, Brahmavriksha, Samidvar.

Unani: Dhaak, Samagh Dhaak, Kamarkas.

Siddha/Tamil: Palasam, Purasus.

Folk: Tesu.

Action: Bark—astringent, styptic (prescribed in bleeding piles, ulcers, haemorrhages, menstrual disorders), anthelmintic. Flowers— astringent, diuretic, emmenagogue (also given for leucorrhoea). A decoction of flowers is given in diarrhoea and haematuria, also to puerperal women. Seeds—clinical use of seeds as an anthelmintic drug is not considered safe in humans.

Leaves—antibacterial. Stem bark— antifungal.

An aqueous extract of flowers has shown hepatoprotective activity against CCl4-induced liver injury in albino rats.

Extracts of flowers have exhibited significant anti-oestrogenic activity in mice. The seed suspension, on oral administration to albino rats (175 and 350 mg/kg body weight), showed 38.46 and 68.75% cases, respectively, where pregnancy was not interrupted but foetus was malformed.

Alcoholic extract of the whole plant produced persistent vasodepression in cats.

The plant contains flavonoids and glucosides—butin, butrin, isobutrin and palastrin. Flowers contain butrin, coreopsin, monospermoside and their derivatives and sulphurein; also chal- cones.

Dosage: Stem bark—5-10 g powder (API Vol. II); flower—3-6 g powder; seed—3 g powder; gum—0.5-1.5 g (API Vol. IV.)... butea monosperma

Caccinia Crassifolia

O. Kuntze.

Synonym: C. glauca Savi.

Family: Boraginaceae.

Habitat: Native to Baluchistan. Available in Indian market as Gaozabaan.

Unani: Gaozabaan. (According to National Formulary of Unani Medicine, Borago officinalis Linn. and other species of Boraginaceae are used as Gaozabaan.)

Action: Leaf—diuretic, antiinflammatory, demulcent; used for strangury, asthma and cough.

The stems and leaves gave sapoge- nins—caccigenin, caccigenin lactone and 23-deoxycaccigenin; rutin and a saponin derived from caccigenin. The leaves also gave a glucoside, cac- cinin. Caccinin and its aglucone cac- cinetin (which is the dimethylallyl ester of caffeic acid) is diuretic; saponins exhibit anti-inflammatory activity.

Flowers contain pyrrolizidine alkaloid, the diester of retronecine. Ben- zoic acid has also been isolated from the flowers.... caccinia crassifolia

Calophyllum Apetalum

Willd.

Callicarpa macrophylla Vahl.

Synonym: C. incana Roxb.

Family: Verbenaceae.

Habitat: Sub-Himalayan tracts, from Hazara eastwards to Assam, up to 1,500 m.

English: Perfumed Cherry.

Ayurvedic: Priyangu, Priyan- gukaa, Priyaka, Gandhphali, Gandhpriyangu, Phalini, Vanitaa, Kaantaa, Kaantaahvaa, Shyamaa, Anganaapriya.

Unani: Habb-ul-Mihlb (Prunus mahaleb Linn., Rosaceae).

Siddha/Tamil: Gnazhal, Chokkala. (Fruits of Aglaia roxburghiana Miq. are used as Priyangu.)

Action: Leaves—applied hot in rheumatic pains. Smoked to relieve headache. Seed—paste used in stomatitis. Wood—paste used in mouth and tongue sores. Seeds and roots—employed as stomachic. Bark—used in rheumatism and diseases of genitourinary tract. The Ayurvedic Pharmacopoeia of India indicated the use of the fruit in emesis and giddiness.

The seeds and leaves contain cal- literpenone and its monoacetate; the former also contain fatty acids, beta- sitosterol and its beta-D-glucoside.

Synonym: C. wightianum T. Anders.

Family: Guttiferae; Clusiaceae.

Habitat: The evergreen forests of Western Ghats up to 330 m.

Siddha/Tamil: Shirupinnai.

Action: Resin—antiphlogistic, anodyne. Seed oil—antileprotic.

The leaves, stem, bark and root contain friedelin. Leaves also contain canophyllol and a triterpene lactone; stem, beta-amyrin; bark, apetalic acid. Heartwood contains a clathrate named wightianone palmitic acid. Wood contains mesoinositol.... calophyllum apetalum

Calotropis Procera

(Ait.) R.Br.

Family: Asclepiadaceae.

Habitat: An evergreen shrub distributed in West and Central India.

English: Swallow-Wart, Milk Weed, (purple-flowered), King's Crown.

Ayurvedic: Alarka, Surya, Su- uryaahvya, Vikirna, Vasuka, Tapana, Tuulaphala, Kshirparna, Arkaparna, Aasphota.

Unani: Aakh, Madaar, Ashar.

Siddha/Tamil: Vellerukku, Erukku.

Action: The plant is used against bronchial asthma (especially flowers with black pepper). Leaves—used for treating chronic cases of dyspepsia, flatulence, constipation and mucus in stool. Seed oil— geriatric and tonic. Leaves, flowers and root-bark oil—antimicrobial (maximum activity in leaves). The Ayurvedic Pharmacopoeia of India indicated the use of the root and leaf in asthma and dyspnoea; stem bark in diseases of the spleen.

Root bark contains benzoylline- olone and benzolisolineolone. Root, stem and leaves, also latex contain beta-amyrin. Flowers contain evanidin 3-rhamnoglucoside. The plant contains a cardenolide, proceragenin, an antibacterial principle.

The latex is given for treating epilepsy, also in painful, joints and swellings. The latex exhibited anti-inflammatory activity in carrageenan-and formalin- induced rat paw oedema model.

The herb can alter menstrual cycle and temporarily inhibit ovulation. Cardiac glycosides may be additive when combined with Digoxin. (Sharon M. Herr.)

Dosage: Leaf—250-750 mg powder; root—1-3 g for decoction (API Vol. I); stem bark—0.5-1 g powder (API Vol. III). Milky juice—500 mg to 1 g (CCRAS.)

Action: Anti-inflammatory. Root— hypocholesterolaemic. Poisonous to human beings in mature stages.

The flowers contain flavonoids, 7- rhamnosides, 3-glucosides and 3-glu- co-7-rhamnosides of kaempferol and quercetin. Roots gave triterpenoid glycosides, which decreased serum cholesterol and total protein and increased blood sugar equivalent to bu- tadione in rats.

EtOH (50%) extract of the plant exhibits CNS depressant and hypotensive activity in rat.... calotropis procera

Cardiospermum Halicacabum

Linn.

Family: Sapindaceae.

Habitat: Throughout the plains of India, as a wild climber.

English: Ballon Vine, Winter Cherry, Heartseed.

Ayurvedic: Kaakatiktaa, Kaakaadani, Karnsphotaa, Shatakratulataa.

Unani: Habb-e-Qilqil.

Siddha/Tamil: Mudukottan, Kottavan.

Folk: Kanphotaa, Kanphuti, Lataaphatakari. Used as Jyotishmati in Bengal.

Action: Used in rheumatism, lumbago, skeletal fractures, nervous diseases, amenorrhoea, haemorrhoids, erysipelas. The herb is used in hairoils for treating dandruff, alopecia and for darkening hair.

The plant extract showed significant analgesic and anti-inflammatory activity and sedative effect on CNS. The drug also showed (transient) vasode- pressant activity.

The leaves contain beta-sitosterol and its D-glucoside, an alkaloid, oxalic acid and amino acids. The presence of a saponin and quebrachitol is reported in the plant.

The leaves and stem are used in preparations used against common cold. Alcoholic extract of the plant exhibits antisickling and antiarthritic activity. Seeds have positive anabolic activity and increase body weight by inducing a positive nitrogen balance.

The alkaloid fraction from the seeds showed hypotensive activities and cardiac inhibition in anaesthetized dogs; blocked spasmogenic effects of acetyl- choline, histamine and 5-HT on guinea pig ileum, biphasic effort on frog rec- tus abdominis muscle. The seeds also showed antibacterial activity.

Dosage: Whole plant—50-100 ml decoction. (CCRAS.)... cardiospermum halicacabum

Carissa Carandas

Linn. var. congesta (Wt.) Bedd.

Family: Apocynaceae.

Habitat: Throughout India.

English: Christ's Thorn, Bengal Currant.

Ayurvedic: Karinkaara, Karamarda, Krishnapaakphal, Kshirphena, Sushena, (Karamardakaa is equated with C. spinarum Linn.)

Unani: Karondaa.

Siddha/Tamil: Kalakke.

Action: Used for acidity, flatulence, poor digestion, as a slimming diet. Juice of the fresh plant is used for infected wounds that refuse to heal. Root—paste used for diabetic ulcer.

The Ayurvedic Pharmacopoeia of India indicated the stem bark in obstinate skin diseases, and the root in urinary disorders.

Alcoholic extract of roots exhibit hypotensive activity. Roots yield car- dioactive compounds; cardiotonic activity is due to glucoside of odoroside H. Fresh fruits are rich in ascorbic acid (105 g/100 g fruit juice). The seeds are rich in potassium (360 mg/100 g fresh matter).

Dosage: Stem bark—48 g for decoction. (API Vol. II); root— 1-3 g (API Vol. III).... carissa carandas

Carthamus Tinctorius

Linn.

Family: Asteraceae.

Habitat: Cultivated mainly as an oil-seed crop in Madhya Pradesh, Maharashtra.

English: Safflower.

Ayurvedic: Kusumbha, Vahin- shikhaa, Vastraranjaka, Kusum.

Unani: Qurtum.

Siddha/Tamil: Chendurakam.

Action: Oil—aids prevention of arteriosclerosis, coronary heart disease and kidney disorders as a polyunsaturated fat. Flowers— stimulant, sedative, diuretic, emmenagogue; used in fevers and eruptive skin conditions, measles.

Charred safflower oil is used in rheumatism and for healing sores.

Key application: Dried flowers— in cardiovascular diseases, amen- orrhoea, dysmenorrhoea and retention of lochia; also in wounds and sores with pain and swelling. (Pharmocopoeia of the People's Republic of China, 1997.)

Safflower contains carthamone, lig- nans and a polysaccharide. The polysaccharide, composed of xylose, fructose, galactose, glucose, arabinose, rhamnose and uronic acid residues, stimulates immune function in mice. It induced antibody formation in mice following peritoneal injection. Extracts of flowers have also been tested in China on blood coagulation, where a prolongation of clothing time was observed and platelet aggregation inhibited. Chinese research indicates that Safflower flowers can reduce coronary artery disease, and lower cholesterol levels. Flowers and seeds exhibit lipase activity. The flower extract also exhibited anti-inflammatory, sedative and analgesic effect and inhibitory effect on spontaneous motor activity.

The plant contains a propanetriol derivative, which can be used for the treatment of circulatory disorders.

Recent research suggests that improving the lipid profile might not be as important to reducing the risk of cardiovascular disease as suggested. (Natural Medicines Comprehensive Database, 2007.)

Safflower is contraindicated in pregnancy, gastric disorders, excessive menstruation, haemorrhagic diseases.

Wild and thorny Safflower, growing in the arid tract of Haryana and Punjab (locally known as Kantiaari, Poli, Poiyan) is equated with C. oxy- cantha Bieb. The plant is diuretic. Seed oil is applied topically to ulcers. The plant contains a sesquiterpene gly- coside. Aerial parts contain hinesol- beta-D-fucopyranoside. The plant also contains luteolin-7-glucoside.

Dosage: Leaf—3-6 g powder. (CCRAS.)... carthamus tinctorius

Cassia Angustifolia

Vahl.

Synonym: C. senna Linn. var. senna.

Family: Caesalpiniaceae.

Habitat: Native to Sudan and Arabia. Now cultivated mainly in Tirunelveli and Ramnathpuram districts and to a lesser extent in Madurai, Salem and Tiruchirapalli districts of Tamil Nadu. Also grown on a small scale in Cuddapah district of Andhra Pradesh and certain parts of Karnataka.

English: Indian Senna, Tinnevelly Senna.

Ayurvedic: Svarna-pattri, Maarkandikaa, Maarkandi.

Unani: Sannaa, Sanaa-makki, Senaai, Sonaamukhi, Sanaa-Hindi.

Siddha/Tamil: Nilaavaarai.

Folk: Sanaai.

Action: Purgative (free from astringent action of rhubark type herbs, but causes gripe), used in compounds for treating biliousness, distention of stomach, vomiting and hiccups. Also used as a febrifuge, in splenic enlargements, jaundice, amoebic dysentery. Contraindicated in inflammatory colon diseases.

Key application: Leaf and dried fruit—in occasional constipation. (German Commission E.) As a stimulant laxative. (The British Herbal Pharmacopoeia.) 1,8- dihydoxy-anthracene derivatives have a laxative effect. This effect is due to the sennosides, specifically, due to their active metabolite in the colon, rheinanthrone. The effect is primarily caused by the influence on the motility of the colon by inhibiting stationary and stimulating propulsive contractions. (German Commission E, ESCOP, WHO.) Seena has been included in I.P. as a purgative.

Most of the Senna sp. contain rhein, aloe-emodin, kaempferol, isormam- netin, both free and as glucosides, together with mycricyl alcohol. The purgative principles are largely attributed to anthraquinone derivatives and their glucosides.

Senna is an Arabian name. The drug was brought into use by Arabian physicians for removing capillary congestion (pods were preferred to leaves).

The active purgative principle of senna was discovered in 1866.

Cassia acutifolia Delile is also equated with Maarkandikaa, Svarna-pattri, Sanaai.

Dosage: Leaves—500 mg to 2 g (API Vol. I.)... cassia angustifolia

Cassia Fistula

Linn.

Synonym: C. rhombifolia Roxb.

Family: Caesalpiniaceae.

Habitat: Cultivated as an ornamental throughout India.

English: Indian Laburnum, Purging Cassia, Golden Shower.

Ayurvedic: Aaragvadha, Chatu- raangula, Kritamaala, Kritmaalaka, Karnikaara, Shampaaka, Praagra- ha, Raajvrksha, Nripapaadapa, Raajadruma, Vyaadhighaataka, Aarevata.

Unani: Amaltaas, Khyaarshambar.

Siddha/Tamil: Sarakkonrai.

Folk: Amaltaasa.

Action: Flowers and pods— purgative, febrifugal, astringent, antibilious. Seed powder—used in amoebiasis.

The Ayurvedic Pharmacopoeia of India indicated the fruit pulp for constipation, colic, chlorosis and urinary disorders.

Pulp of the pod contains anthraqui- none glycosides, sennosides A and B, rhein and its glucoside, barbaloin, aloin, formic acid, butyric acid, their ethyl esters and oxalic acid. Presence of pectin and tannin is also reported.

Seeds gave galactomannan free sugars and free amino acids; extract laxative, carminative, cooling and antipyretic properties.

Flowers gave ceryl alcohol, kaem- pferol, rhein and a bianthraquinone glycoside, fistulin.

Leaves gave free rhein, its glyco- sides—sennosides A and B.

Cassia javanica L., a related species found in West Bengal, Maharashtra and Tamil Nadu, is used as a substitute for Cassia fistula.

Dosage: Fruit pulp—5-10 g powder. (API Vol. I.)... cassia fistula

Cassia Occidentalis

Linn.

Family: Calsalpiniaceae.

Habitat: Throughout India, up to an altitude of 1,500 m.

English: Coffee Senna, Foetid Cassia, Negro Coffee.

Ayurvedic: Kaasamarda, Kaasaari.

Unani: Kasondi.

Siddha/Tamil: Paeyaavarai, Thagarai.

Folk: Kasondi (bigger var.).

Action: Purgative, diuretic, febrifugal, expectorant, stomachic. Leaves—used internally and externally in scabies, ringworm and other skin diseases. A hot decoction is given as an antiperiodic. Seeds— used for cough, whooping cough and convulsions. Roasted seeds (roasting destroys the purgative property) are mixed with coffee for strength.

The pods contain sennosides and anthraquinones; seeds polysacchari- des, galactomannan; leaves dianthron- ic hetroside; pericarp apigenin; roots emodol; plant xanthone—cassiolin; seeds phytosterolin; flowers physcion and its glucosides, emodin and beta- sitosterol.

The volatile oil obtained from the leaves, roots and seeds showed antibacterial and antifungal activity.

The seeds, when fed to animals, resulted in weight loss and also were found to be toxic to experimental animals. Leaves are preferred to quinine as a tonic, seeds are considered as a hae- mateinic toxic and root is used as a hepatic tonic.

Dosage: Seed—3-6 g powder; leaf—10-20 ml juice; root bark— 50-100 ml decoction. (CCRAS.)... cassia occidentalis

Cheiranthus Cheiri

Linn.

Family: Cruciferae; Brassicaceae.

Habitat: Native to South Europe, grown as an ornamental.

English: Wall-flower, Gilli Flower.

Unani: Tudri (Surkh, Safed, Zard)

Action: Flowers—cardioactive, tonic, antispasmodic, purgative, emmenagogue, deobstruent (used in liver diseases and sexual debility). Seeds— stomachic, diuretic, expectorant (in bronchitis and asthma); also goitrogenic. Juice of leaves and seeds—antibacterial.

Flowers contain flavonoids (querce- tin and rhamnetin derivatives); seeds contain high levels of cardiac aglycones (30 cardiac glycosides have been isolated); oil contains cherinine, a glucoside of the digitalis group.

In Unani medicine, the drug is used as a tonic to the male reproductive system, but recent findings do not validate its therapeutic use. The flavonoid, kaempferol, isolated from the young plant, inhibits spermatogenesis and alters leydig cell number and diameter, affecting the fertility.... cheiranthus cheiri

Chlorophytum Arundinaceum

Baker.

Family: Liliaceae.

Habitat: The Himalaya from Nepal to Bhutan, Assam and Bihar.

Ayurvedic: Shveta-Musali. (Considered different from Asparagus adscendens Roxb.)

Unani: Musali Safed, Biskandri.

Siddha/Tamil: Vallaimusali.

Folk: Nising, Tibbati Ginseng.

Action: Tuber—nervine and general tonic. The plant is used as a substitute for onion. Fried powder of the root is chewed in aphthae of mouth and throat. A decoction of the root with turmeric is given in rheumatism.

The roots contain a bibenzyl xylo- side, the steroidal sapogenins, besides stigmasterol and its glucoside, nona- cosane and tetracosanoic, and triacon- tanoic acids.

The root extract exhibited good adaptogenic properties. The fruits yield a polysaccharide, galactoglucan.... chlorophytum arundinaceum

Citrullus Colocynthis

Schrad.

Family: Cucurbitaceae.

Habitat: Throughout India.

English: Colocynth Bitter Apple.

Ayurvedic: Indravaaruni, Indraval- li, Indravaarunikaa, Gavaakshi, Chitraa, Chitraphalaa, Indraasuri, Mrigaani, Mrigairvaaru, Vishaalaa, Vishaalyka, Indraayana. Ain- dri (also equated with Bacopa monnieri).

Unani: Hanzal.

Siddha/Tamil: Kumatti.

Action: Dried pulp of ripe fruit— cathartic, drastic purgative, irritant and toxic. The pulp is used for varicose veins and piles. A paste of root is applied to various inflammations and swellings. The cataplasm of leaves is applied in migraine and neuralgia.

The Ayurvedic Pharmacopoeia of India indicated the use of the fruit in jaundice; the root in diseases of the liver and spleen and the leaf in cutaneous affections and alopecia.

Colocynth contains up to 3% cucur- bitacin. The drug and its preparations cause drastic irritation of the gastrointestinal mucosa and haemorrhages.

Cucurbitacins include cucurbitacin E-, J-, L-glucosides. In addition, the pulp contains caffeic acid derivatives (chlorogenic acid).

Roots contain aliphatic compounds. Ethanolic extract (50%) shows significant anti-inflammatory activity in albino rats.

Leaves and flowers contain querce- tin and kaempferol. The ethanolic extract of leaves and flowers exhibits antibacterial activity against a number of Gram-positive and Gram-negative bacteria.

The powder is toxic at 0.6-1.0 g. The fruit exhibited carcinogenic activity in animal studies.

Dosage: Dried fruit—125-500 mg powder. (API Vol. III.) Root—1- 3 g. powder. (CCRAS.) Dried leaf— for external use. (API Vol. II.)... citrullus colocynthis

Citrus Maxima

(Burm.) Merrill.

Synonym: C. decumana Watt. C. grandis (L.) Osbeck

Family: Rutaceae.

Habitat: North-eastern region up to 1,500 m in Assam and Tripura.

English: Pummelo, Shaddock.

Ayurvedic: Madhukarkatikaa.

Unani: Chakotra.

Siddha/Tamil: Pambalimasu.

Folk: Mahaa-nibu, Sadaaphal.

Action: Fruit—cardiotonic. Leaves, flowers and rind—used as a sedative in nervous affections. Leaves— used in convulsive cough, chorea, epilepsy, also in the treatment of haemorrhagic diseases. A lotion of boiled leaves used hot in painful swellings. The essential oil from fresh leaves exhibits dermatophytic, and fungistatic activity.

The root-bark contains beta-sitos- terol and acridone alkaloids. It also contains several coumarins. The alkaloids and coumarins show antimicrobial acitivity.

The essential oil from the leaves and unripe fruits contain 20% limonin, 30% nerolol, 40% nerolyl acetate and 3% geraniol. diosmin, beta-sitosterol and beta-D- glucoside. The roots contain campes- terol, stigmasterol, sitosterol and cholesterol.

Aqueous extract of the peel showed hypotensive action in dogs.

The fruits and seeds are a cardioton- ic; found useful in palpitation.

Dosage: Fruit—10-20 ml juice. (API Vol. III.) Leaf, flower, fruit, root— 50-100 ml decoction. (CCRAS.)... citrus maxima

Clerodendrum Phlomidis

Linn.f.

Synonym: C. multiflorum (Burm. f.) O. Kuntze.

Family: Verbenaceae.

Habitat: Throughout India, in the drier parts.

Ayurvedic: Agnimantha, Tarkaari, Vikraantaa, Jayanti, Jai, Jayaa, Ganikaarikaa, Vaijayanti, Bigger var. is equated with Premna integri- folia Linn., Shriparni, Naadeyi.

Siddha/Tamil: Tazhuthaazhai.

Folk: Laghu Arni.

Action: Plant parts used in dyspepsia, stomachache, colic, cholera, dysentery, postnatal fever, during convalscence from measles. Root and bark—bitter tonic, used in debility and nervous disorders.

The Ayurvedic Pharmacopoeia of India indicated the use of root in dysuria and retention of urine.

Flavonoids, scutellarein and pec- tolinarin, have been isolated from the leaves. Stems gave d-mannitol, beta- sitosterol, its glucosides and ceryl alcohol. The roots contain ceryl alcohol, clerodin, clerosterol and clerodendrin A.

The ethanolic extract of leaves exhibited hepatoprotective activity. The aqueous extract of leaves exhibited in vitro anthelmintic activity. The plant also exhibited antidiabetic activity.

Dosage: Root—12-24 g for decoction. (API Vol. III.)... clerodendrum phlomidis

Corchorus Capsularis

Linn.

Family: Tiliaceae.

Habitat: Throughout warmer parts of India; extensively cultivated in West Bengal.

English: White Jute.

Ayurvedic: Kaala shaaka.

Siddha/Tamil: Pirattai-keerai.

Folk: Naadi shaaka, Narichaa. Titapat (Bengal).

Action: Leaves—stomachic, carminative, diuretic, antidysenteric (dried leaves). Seeds—purgative.

Seeds contain cardiac glycosides. These include two monosides, helveti- coside and corchoroside A and two polar glycosides, erysimoside and olitori- side. Leaves contain beta-sitosterol- glucoside. Corchoroside A exhibited cardiotonic properties.

The aqueous/alcoholic extracts, containing polysaccharides, may be used in preparations of skin cosmetics or hair preparations for their moisturizing effect.... corchorus capsularis

Coleus

Coleus spp.

Lamiaceae

The genus Coleus of the family Lamiaceae (Labiatae) comprises a number of herbaceous medicinal plants which are particularly employed in home remedies for various ailments. Three species are most popular and commonly cultivated. They are Coleus aromaticus, C. vettiveroides and C. forkoshlii.

1. Coleus aromaticus Benth. syn. C. amboinicus Lour., Plectranthus amboinicus (Lour.) Spreng.

Eng: Country borage, Indian borage;

San: Karpuravalli, Sugandhavalakam;

Hin: Patharchur;

Ben: Paterchur;

Mal: Panikkurkka, kannikkurkka;

Tam: Karpuravalli;

Kan: karpurahalli;

Tel: Sugandhavalkam.

It is found through out the tropics and cultivated in homestead gardens. It is a large succulent aromatic perennial herb with hispidly villous or tomentose fleshy stem. Leaves are simple, opposite, broadly ovate, crenate and fleshy. Flowers are pale purplish in dense whorls at distant intervals in a long slender raceme. Fruits are orbicular or ovoid nutlets. The leaves are useful in cephalagia, otalgia, anorexia, dyspepsia, flatulence, colic, diarrhoea, cholera, halitosis, convulsions, epilepsy, cough, asthma, hiccough, bronchitis, strangury, hepatopathy and malarial fever (Warrier et al,1995).

2. Coleus vettiveroides K.C. Jacob, syn. Plectranthus vettiveroides (Jacob) Singh & Sharma.

San: Valakam, Hriberam;

Hin: Valak;

Mal: Iruveli;

Tam: Karuver;

Tel: Karuveru,

It is seen in tropical countries and cultivated in gardens. It is a small profusely branched, succulent aromatic herb with quadrangular stems and branches and deep straw coloured aromatic roots. Leaves are glandular hairy, broadly ovate with dentate margins and prominent veins on the bark. Blue flowers are borne on terminal racemes. Fruits are nutlets. The whole plant is useful in hyperdipsia, vitiated conditions of pitta, burning sensation, strangury, leprosy, skin diseases, leucoderma, fever, vomiting, diarrhoea, ulcers and as hair tonic.

3. Coleus forskohlii Briq. syn. C. barbatus Benth.

Hin: Garmai

Kan: Maganiberu, Makandiberu

Guj: Maimul

It is a perennial aromatic herb grown under tropical to temperate conditions for its carrot-like tubers which are used as condiments in the preparation of pickles. Its tuberous roots are an exclusive source of a diterpenoid forskolin which has the unique property of activating almost all hormone sensitive adenylate cyclase enzymes in a biological system. It is useful in the treatment of congestive heart failure, glaucoma, asthma, cancer and in preventing immature greying of hair (Hegde,1997).

Agrotechnology: The Coleus group of plants grows in tropical to subtropical situations and in warm temperate climatic zone on mountains of India, Nepal, Burma, Sri Lanka, Thailand and Africa. It comes up well on the sun exposed dry hill slopes from 300m to 1800m altitude. A well drained medium fertile soil is suitable for its cultivation. it is propagated vegetatively through stem and root cuttings. Vine cuttings to a length of 10-15cm from the top portion are most ideal for planting. The land is ploughed or dug to a depth of 15-20cm and ridges are formed 30cm apart. Vine cuttings are planted on the ridges at 30cm spacing after incorporating basal manure. 10t of FYM and NPK at 50:50:50kg/ha are incorporated into the soil. Top dressing of N and K is also suggested for improved yields. Weeding and earthing up at 45 days after planting along with topdressing is highly beneficial. Bacterial wilt and root knot nematode are reported in the crop. Drenching the soil with fungicide, deep ploughing in the summer, burning of crop residues and crop rotation are helpful to tide over the disease and pest problem. The crop can be harvested after 5-6 months.

Properties and activity: The medicinal property of Coleus amboinicus is attributed to codeine, carvacrol, flavones, aromatic acids and tannins present in the plant. The essential oil from the plant contains carvacrol, ethyl salicylate, thymol, eugenol and chavicol. Leaves also contain cirsimaritin, -sitosterol- -D-glucoside and oxalacetic acid. Leaves are bitter, acrid, thermogenic, aromatic, anodyne, appetising, digestive, carminative, stomachic, anthelmintic, constipating, deodorant, expectorant, diuretic and liver tonic.

Coleus vettiveroides is bitter, cooling, diuretic, trichogenous and antipyretic.

Coleus forskohlii roots are rich in diterpenoids like forskolin, coleonols, coleons, barbatusin, cyclobutatusin, coleosol, coleol, coleonone, deoxycoleonol, 7-deacetylforskolin and 6-acetyl-7-deacetylforskolin. Its root is spasmolytic, CNS active, hypothermic and diuretic. Forskolin is bronchodialative and hypotensive (Hussain et al,1992). Forskolin is also useful in preventing the clotting of blood platelets, in reducing intraocular pressure in glaucoma and as an aid to nerve regeneration following trauma (Sharma, 1998)... coleus

Coomb Teak

Gmelina arborea

Verbenaceae

San: Gumbhari;

Hin:Gamari, Jugani-chukar;

Mal: Kumizhu, Kumpil;

Guj: Shewan; Pun:Gumbar; Mar: Shivanasal;

Kan: Kummuda;

Tam: Uni, Gumadi;

Tel: Gummadi;

Importance: Coomb teak, Candahar tree or Kashmeeri tree is a moderate sized, unarmed, deciduous tree which is a vital ingredient of the ”dasamula” (group of ten roots). The whole plant is medicinally very important. It promotes digestive power, improves memory, overcomes giddiness and is also used as an antidote for snake bite and scorpion sting. Roots are useful in hallucination, fever, dyspepsia, hyperdipsia, haemorrhoids, stomachalgia, heart diseases, nervous disorders, piles and burning sensation. Bark is used in fever and dyspepsia. Leaf paste is good for cephalagia and leaf juice is a good wash for foul ulcers and is also used in the treatment of gonorrhoea and cough. Flowers are recommended for leprosy, skin and blood diseases. The fruits are used for promoting the growth of hair and in anaemia, leprosy, ulcers, constipation, strangury, leucorrhoea, colpitis and lung disease.

Wood is one of the best and most reliable timber of India. It is used for making furniture, planks, carriages, printing boxes, musical instruments, shafts, axles, picture frames, jute bobbins, calipers, ship buildings, artificial limbs and stethoscopes.

In south India the bark of the tree is used by arrack manufacturers to regulate the fermentation of toddy. The plant is also grown in garden or avenues (Dey, 1988; Sivarajan and Indira, 1994).

Distribution: The plant is found wild throughout India from the foot of Himalayas to Kerala and Anadamans, in moist, semideciduous and open forests upto an altitude of 1500 m. It is also distributed in Sri Lanka and Philippines.

Botany: Gmelina arborea Roxb. Syn. Premna arborea Roth. belongs to Family Verbenaceae. It is an unarmed deciduous tree growing up to 20m height with whitish grey corky lenticellate bark, exfloliating in thin flakes. Branchlets and young parts are clothed with fine white mealy pubescence. Leaves are simple, opposite, broadly ovate, cordate, glandular, glabrous above when mature and fulvous-tomentose beneath. Flowers brownish yellow in terminal panicle. Calyx campanulate, pubescent outside and with 5 lobes. Corolla showy brownish yellow with short tube and oblique limbs. Stamens 4, didynamous and included. Ovary is 4 chambered with one ovule each; style slender ending in a bifid stigma. Fruits are fleshy ovoid drupes, orange yellow when ripe. Seeds 1 or 2, hard and oblong.

Agrotechnology: Coomb teak is a sun loving plant. It does not tolerate drought. But it grows in light frost. Rainfall higher than 2000mm and loose soil are ideal. The best method of propagation is by seeds but rarely propagated vegitatevely by stem cuttings also. Seed formation occurs in May-June. Seeds are dried well before use. They are soaked in water for 12 hours before sowing. Seed rate is 3kg/ha. Seeds are sown in nursery beds shortly before rains. Seeds germinate within one month. Seedlings are transplanted in the first rainy season when they are 7-10cm tall. Pits of size 50cm cube are made at a spacing of 3-4m and filled with sand, dried cowdung and surface soil, over which the seedlings are transplanted. 20kg organic manure is given once a year. Irrigation and weeding should be done on a regular basis. The common disease reported is sooty mould caused by Corticium salmonicolor which can be controlled by applying a suitable fungicide. The tree grows fast and may be ready for harvesting after 4 or 5 years. This plant is coppiced and traded. The roots are also used for medicinal purposes. The tree may stand up to 25 years.

Properties and activity: Roots and heart wood of Coomb teak are reported to contain gmelinol, hentriacontanol, n-octacosanol and -sitosterol. The roots contain sesquiterpenoid and apiosylskimmin, a coumarin characterised as umbelliferone-7-apiosyl glucoside and gmelofuran. The heart wood gives ceryl alcohol, cluytyl ferulate, lignans, arboreol, gmelonone, 6”-bromo isoarboreol, lignan hemiacetal and gummidiol. Leaves yield luteolin, apigenin, quercetin, hentriacontanol, -sitosterol, quercetogenin and other flavons. Fruits contain butyric acid, tartaric acid, and saccharine substances (Asolkar et al, 1992; Dey, 1988).

The roots are acrid, bitter, tonic, stomachic, laxative, galactogogue, demulcent, antibilious, febrifuge and anthelmintic. Bark is bitter, hypoglycaemic, antiviral, anticephalalgic and tonic. The leaves are demulcent, antigonorrhoeic and bechic. Flowers are sweet, refrigerant, astringent and acrid. Fruits are acrid, refrigerant, diuretic, astringent, aphrodisiac, trichogenous, alterant and tonic (Warrier et al; 1995).... coomb teak

Corchorus Fascicularis

Lam.

Family: Tiliaceae.

Habitat: Throughout warmer parts of India.

Ayurvedic: Chanchuka, Chanchu.

Folk: Chanchu shaaka, Baaphali.

Action: Astringent, spasmolytic, restorative, mucilaginous.

The plant contains betulinic acid and beta-sitosterol. Seeds yield cardeno- lides including trilocularin. The glyco- sides of the plant were found to be devoid of any effect of its own on smooth muscle of guinea pig ileum, but produced spasmolytic effect against acetyl- choline, histamine and bradykinin. Direct action of the drug was observed on rabbit intestines. Slight cardiac depressant effect was found on isolated amphibian heart preparation.

Corchorus depressus (L.) Christensen, found in drier parts of North India, is known as Bhauphali (Delhi).

The Plant is used as a cooling medicine in fevers; its mucilage is prescribed in gonorrhoea, also for increasing the viscosity of seminal fluid. An extract of the plant is applied as a paste to wounds.

The plant contains alpha-amyrin derivatives, together with apigenin, luteolin, sitosterol and its glucoside. Presence of quercetin and kaempferol has been reported in leaves and flowers.

The plant exhibits antimicrobial and antipyretic activities.... corchorus fascicularis

Costus

Costus speciosus

Zingiberaceae

San: Pushkara, Kashmeera, Kemuka;

Hin: Kebu, Keyu, Kust;

Ben: Keu, Kura

Mal: Channakkizhangu, Channakoova;

Tam: Kostam; Mar: Penva;

Tel: Kashmeeramu

Importance: Costus is one of the plants which contains diosgenin in its rhizome. It is widely used as starting material in the commercial production of steroidal hormones. The rhizomes are useful in vitiated conditions of kapha and pitta, burning sensation, flatulence, constipation, helminthiases, leprosy, skin diseases, fever, hiccough, asthma, bronchitis, inflammation and aneamia. It is used to make sexual hormones and contraceptives (Warrier et al,1994).

Distribution: The plant is widely distributed in Asia and other tropical countries like India, Nepal, Pakistan, Sri Lanka and China. In India, it occurs mostly in Arunachal Pradesh, Meghalaya, Nagaland, Tamil Nadu, Assam, Tripura and Kerala.

Botany: Costus speciosus (Koenig.) Sm. belonging to the family Zingiberaceae consists of two varieties viz., var. nepalensis Rose., found only in Nepal and Arunachal Pradesh and var. argycophyllus Wall., having a wide distribution in India.

The plant is a succulent herb with long leafy spirally twisted stems, 2-3m in height and horizontal rhizomes. Leaves are simple, spirally arranged, oblanceolate or oblong, glabrous above, silky pubescent beneath with broad leaf sheaths. Flowers are white, large, fragrant, arranged in dense terminal spikes. Bracts are bright red. The single stamen present is perfect, lip large with incurved margins. Fruits are globose or ovoid capsules with obovoid or sub- globose seeds (Warrier et al,1994).

Agrotechnology: Costus can be raised under a wide range of agroclimatic conditions. It prefers sandy loam soil for good growth. Propagation is by rhizomes. The best season for planting is April- May. The seed rate recommended is 2-2.4t/ha. The spacing adopted is 50x50cm. After an initial ploughing FYM or poultry manure should be applied at the rate of 30t/ha and the field is to be ploughed again irrigated and prepared to obtain a fine seed bed. Furrows are opened and the rhizome pieces are placed horizontally at a depth of 8-10cm and covered with soil. Care is taken to place the eye buds facing upwards. After 70-75 days about 90-95% sprouting is obtained. Desiccation of the young sprouts have been observed in the hot summer months, necessitating liberal water supply during the period. As September-November is the period of maximum tuberization at least two irrigations should be given at that time. One during the sprouting period of the crop followed by two more keeps the crop fairly free of weeds. Application of 37t/ha of poultry manure and fertilizers, 60kg P2O5 and 40kg K2O /ha as a basal doze, along with 80kg N/ha applied in 3 equal split dozes will take care. Crop is harvested at the end of seven months. Harvesting includes 2 operations, cutting the aerial shoots and digging out the rhizomes. Cost of production of diosgenin ranges from Rs. 271-300/kg (Atal, et al,1982).

Properties and activity: Tubers and roots contain diosgenin, 5 -stigmast-9(11)-en-3 ol, sitosterol- -D- glucoside, dioscin, prosapogenins A and B of dioscin, gracillin and quinones. Various saponins, many new aliphatic esters and acids are reported from its rhizomes, seeds and roots. Seeds, in addition, contain - tocopherol. Saponins from seeds are hypotensive and spasmolytic. Rhizomes possess antifertility, anticholinestrase, antiinflammatory, stimulant, depurative and anthelmintic activities (Hussain et al, 1992).... costus

Costus Speciosus

(Koenig) Sm.

Family: Zingiberaceae.

Habitat: Assam, North Bengal, Khasi and Jaintia Hills, sub Himalayan tracts of Uttar Pradesh and Himachal Pradesh and Western Ghats.

English: Canereed, Wild Ginger.

Ayurvedic: Kebuka, Kembuka.

Siddha/Tamil: Krrauvam, Malai Vasambu, Ven Kottam.

Folk: Kebu.

Action: Astringent, purgative, depurative, anti-inflammatory (used in gout, rheumatism; bronchitis, asthma, catarrhal fevers, dysuria), anthelmintic, antivermin, maggoticide, antifungal.

The rhizomes contain saponins— dioscin, gracillin and beta-sitosterol- beta-D-glucoside. The alkaloids show papaverine-like smooth-muscle-relaxant activity, cardiotonic activity like that of digitalis and antispasmodic,

CNS-depressant, diuretic and hydro- choleretic activities. Saponins show significant anti-inflammatory and an- tiarthritic activity.

The seeds also contain saponins and exhibit potent and sustained hypoten- sive and bradycardiac activities in dogs with low toxicity and without any haemolytic activity; also weak spasmolytic activity on isolated guinea-pig ileum.

All parts of the plant yield steroidal sapogenin, diogenin (quantity varies from 0.32 to 4%).

(Not to be confused with Kushtha of Indian medicine, Saussurea lappa.)... costus speciosus

Cressa Crética

Linn.

Family: Convolvulaceae.

Habitat: Costal regions of India.

Ayurvedic: Rudanti, Rudantikaa, Rudravanti.

Siddha/Tamil: Uppu Sanaga. Folk: Khardi.

Action: Expectorant, stomachic, antibilious, alterative.

Air-dried, powdered whole plant gave «-octacosanol, scopoletin, um- belliferone, isopimpinellin, beta-sitos- terol and its -D(+)-glucoside and quer- cetin.... cressa crética

Derris Uliginosa

Benth. Derris indica (Lamk.) Bennet.

Synonym: Pongamia pinnata Pierre.

Family: Fabaceae.

Habitat: Native to the Western Ghats. Found all over India on the banks of rivers and streams.

English: Indian Beech. Pongamia oil tree.

Ayurvedic: Naktmaal, Guchpush- pak, Ghritpuur, Udkirya, Karanja.

Siddha/Tamil: Pungu.

Action: Used for skin diseases— eczema, scabies, leprosy, and for ulcers, tumours, piles, enlargement of spleen, vaginal and urinary discharges. Juice of root—used for closing fistulous sores and cleaning foul ulcers. Flowers— used in diabetes. Powder of seeds— used for whooping and irritating coughs of children. Seed oil—used in cutaneous affections, herpes and scabies.

The tree is rich in flavonoids and related compounds. These include simple flavones, furanoflavonoids, chro- menoflavones, chromenochalcones, coumarones, flavone glucosides, sterols, triterpenes and a modified pheny- lalanine dipeptide.

Synonym: D. trifoliate Lour.

Family: Fabaceae.

Habitat: Costal forests of India and the Andamans.

Folk: Paan-lataa (Bengal), Kitani (Maharashtra).

Action: Stimulant, antispasmodic, counter-irritant. Bark—alterative in rheumatism. An oil prepared from the plant is used externally as an embrocation.

The roots contain dehydrorotenone, lupeol and a ketone. Bark contains 9.3% tannic acid. Stems contain tan- nic acid, hexoic, arachidic and stearic acids, ceryl alcohol, isomerides of cholesterol, potassium nitrate, gums and resins.... derris uliginosa

Curry Leaf

Murraya Koenigii

Rutaceae

San: Kalasakh, Kaidaryah

Hin: Mithinim, Katnim

Ben: Barsunga

Mal: Kariveppu, Karuveppu

Tam: Kariveppilai, Karuveppu

Kan: Kari Baeva

Tel: Karivepaku

Ass: Narasingha, Bishahari

Importance: Curry leaf, a plant of homestead gardens has gained importance as a commercial crop and is cultivated for its culinary and medicinal value. The plant is highly esteemed for its leaves which promote appetite and digestion and destroy pathogenic organisms. It is reported to be useful in emaciation, skin diseases, hemopathy, worm troubles, neurosis and poisons. They are useful in vitiated conditions of kapha and pitta, hyperdipna, colic, flatulence, diarrhoea, dysentery, vomiting, inflammations and foul ulcers. “Kaidaryah” drug is prepared using this plant which improves voice, stimulates digestion and destroys concocted poisons in the system. The important preparations using the drug are Kalasadi kasayam, Pamantaka tailam, Jatyadi tailam, Jatyadi ghrtam, etc (Sivarajan et al,1994).

Distribution: Curry leaf is seen in the foot of the Himalaya and Bashahi eastwards to Sikkim and Peninsular India, upto 1700m. It is also found in Sri Lanka, Burma, Indo-China, South China and Hainan. Commercial cultivation in India is limited to Tamil Nadu and Karnataka states.

Botany: The genus Murraya of the family Rutaceae includes the following species:

M. Koenigii (Linn.) Spreng. syn. Bergera koenigii Linn.

M. Exotica Linn. syn. M. paniculata (Linn.) Jack.

Murraya koenigii is a small aromatic tree with dark grey bark and closely crowded spreading dark green foliage. Leaves are imparipinnate and alternate. Leaflets are alternate, obliquely ovate or somewhat rhomboid, gland dotted and strongly aromatic. Flowers are white, arranged in much branched terminal corymbose cymes and fragrant. Fruits are subglobose or ellipsoid berries, purplish black when ripe and 2-seeded (Warrier et al, 1995).

Agrotechnology: Curry leaf tree does not choose a specific climate and can come up even in dry climate too. In places where minimum temperature goes below 13 C, the growth of the shoot will be slightly affected. It comes up well in light textured red soils. DWD-1 and DWD-2 are two improved varieties released from UAS, Dharwad. Curry leaf is propagated by seed. Main field is to be ploughed repeatedly. A spacing of 90-120cm is followed on either side. Pits of size 30cm3 are dug out one month before planting and filled with top soil mixed with well decomposed FYM at the time of planting. Healthy seedlings are planted in the centre of the pits. Then long furrows are formed connecting all the pits to facilitate easy irrigation. The seedlings are irrigated once in 5-7 days upto 3 years and once in 15 days afterwards. The field should be kept free from weeds. Plants may be trained and pruned to maintain a bush of 1m in height. For better growth and yield, each plant is fertilised with 20kg of FYM besides 150:25:50g of N, P2O5, K2O/ year. Attack of aphids in the vegetative stage can be controlled by spraying of dimethoate at 2ml/l of water. Leaves from such sprayed plants should be harvested only after 10 days. Spraying carbendazim at 1g/l can take care of leaf spot diseases. The crop comes to first harvest at the end of first year. The yield of leaves account to 400kg/ha at the end of first year, 2000 to 2200kg/ha in the second and third year harvested at an interval of four months and 2500kg/ha in the fourth year harvested at three months interval. From fifth year onwards it is harvested at 2.5-3 months interval giving an yield of 3500-5000kg/ha (Kumar et al, 1997).

Properties and activity: All parts of the plant, especially the leaves are rich in carbazole alkaloids. These include members with (i) C13 - skeleton -murrayanin, mukoeic acid, mukonine and mukonidine; (ii) C18 - skeleton including gerinimbine, koenimbine, murrayacine, koenigine and koenigicine (koenidine); and (iii) C23- skeleton containing mahanimbine, mahanimbicine, iso- mahanimbicine, mahanine, mahanimbinine, murrayayazoline, murrayazolinine, murrayazolidine, cyclomahanimbine and bicyclomahanimbicine. Other carbazole bases include mukoline, mukolidine (C13 group, from roots), mukonicine (C18 from leaves), the biogenetically significant mukonal (C13, stem-bark), mahanimboline (C23, root-bark), iso- murrayazoline (C23, stem-bark). The leaves gave a coumarin glucoside, scopolin also. Essential oil from leaves contained -caryophylline, -gurjunene, -elemene, - phellandrene, -thujene as major constituents.

The roots, bark and leaves are bitter, acrid, astringent, cooling, aromatic, demulcent, depurative, anthelmintic, febrifuge, stomachic, appetising, carminative, antiinflammatory and antiseptic. Aerial part is spasmolytic and antiprotozoal. Root is antiprotozoal, CVS active and has effect on nictitating membrane. Leaf is hypoglycaemic (Hussain et al,1992).... curry leaf

Dioscorea Prazeri

Prain & Burkill.

Synonym: D. Clarkei Prain & Burkill D. deltoidea Wall. var. sikkimensis Prain

Family: Dioscoreaceae.

Habitat: The Himalaya from Nepal to Bhutan, up to 1,500 m, also in Naga Hills.

Ayurvedic: Neelaalu.

Action: Tuber—antiphthiriac.

The rhizomes are used as a hair wash for killing lice. They contain diogenin (on dry basis) 2.5%. Also obtained are steroidal sapogenins, sito- sterol glucoside, prazerigenin-A gluco- side, prazerigenin-A bioside and 9,10- dihydrophenanthrenes.... dioscorea prazeri

Diospyros Embryopteris

Pers.

Synonym: D. peregrina (Gaertn.) Gurke D. malabarica (Desr.) Kostel.

Family: Ebenaceae.

Habitat: Throughout India in shady wet places and near streams.

English: Gaub Persimmon, Riber Ebony

Ayurvedic: Tinduka, Tinduki, Sphu- urjaka, Kaalaskandha, Asitkaaraka. Nilasaara.

Unani: Tendu.

Siddha/Tamil: Tumbika, Kattatti.

Action: Fruit and stem bark— astringent. Infusion of fruits—used as gargle in aphthae and sore throat. Fruit juice—used as application for wounds and ulcers. Oil of seeds— given in diarrhoea and dysentery Ether extract of fruit—antibacterial. Bark—astringent and styptic, used in menorrhagia, diarrhoea, dysentery and intermittent fevers.

A paste is applied to boils and tumours. The ethyl acetate extract showed antistress and anti-ulcerogenic activity. It also prevented hepatotoxi- city and leucocytosis in experimental animals.

The bark contains betulinic acid, myricyl alcohol, triterpenoids and sa- ponin. The leaves gave beta-sitosterol, betulin and oleanolic acid. Fruit pulp and seeds contain lupeol, betulin, gallic acid, betulinic acid, hexacosane, hex- acosanol, sitosterol, beta-D-glucoside of sitosterol and a triterpene ketone.

Stem bark—antiprotozoal, antiviral, hypoglycaemic, semen-coagulant. Stems yielded nonadecan-7-ol-one.

Dosage: Bark—50-100 ml decoction. (CCRAS.)... diospyros embryopteris

Dolichandrone Falcate

Seem.

Family: Bignoniaceae.

Habitat: Moist forests of central and southern India.

Ayurvedic: Mesha-shringi (also equated with Gymnena sylvestre R. Br.), Vishaanikaa.

Siddha/Tamil: Kattu Varsana, Kaddalatti, Kaliyacca.

Action: Fruits—bitter, carminative, used in diabetes, urinary disorders, bronchitis and skin diseases. Leaves—applied externally to swollen glands. Abortifacient.

The leaves yield luteolin, chrysin and its 7-rutinoside and glucoside.

Fruits are also known as Rshabhaka in the South.... dolichandrone falcate

Dregea Volubilis

(Linn. f.) Benth. ex Hook. f.

Synonym: Wattakaka volubilis (Linn. f.) Stapf.

Family: Asclepiadaceae.

Habitat: Konkan and Maharashtra, also in Bengal and Assam.

Ayurvedic: Suparnikaa, Madhu- maalati. Muurvaa (substitute). Nak-chhikkini.

Siddha/Tamil: Kodippalai.

Action: Root and tender stalks— emetic and expectorant, cause sneezing, used in colds, sinusitis, and biliousness. Leaves—used as an application to boils and abscesses.

The stems and leaves contain a pigment taraxerol, a triterpenoid, kaem- pferol, a glucoside of kaempferol and saponins. Seeds contain a number of pregnane glycosides which do not exhibit digitalis-like action. Root contains a glucoside which lowered carotid blood pressure in mice and dogs when administered intravenously.... dregea volubilis

Drypetes Roxburghii

(Wall.) Hurusawa.

Synonym: Putranjiva roxburghii Wall.

Family: Euphorbiaceae.

Habitat: Wild and cultivated throughout tropical India.

Ayurvedic: Putrajivaka, Sutajva, Putrakamanjari.

Siddha/Tamil: Karupali, Irukolli.

Action: Leaves, fruits and stones of fruits are given in colds and fevers, also in rheumatic affections. Rosaries, made ofhard stones of the fruit, are placed around the necks of children to protect them from diseases.

The seed kernel yield 0.5% of a sharp- smelling essential oil of the mustard oil type. The oil contains isopropyl and 2-butyl isothiocyanates as the main constituents and 2-methyl-butyl isoth- iocyanate as minor component. Anad- ditional glucoside, glucocleomin, has been found in the seed kernels. A glu- cosidic pattern similar to that in the seeds is reported in the shoots and roots. The fruit pulp contains a large proportion of mannitol and small quantities of a saponin glucoside and alkaloid.

The alkaloid is also present in a small quantity in the stones of the fruit.

Dosage: Seed, leaf, bark—3-6 g powder. (CCRAS.)... drypetes roxburghii

Eleusine Indica

Gaertin.

Family: Gramineae, Poaceae.

Habitat: Australia, North America; throughout the warmer parts of the world. In India, in wet plains and low hills and pasture grounds.

English: Crowfoot Grass, Crab Grass.

Ayurvedic: Nandimukha (var.).

Folk: Nandiaa (Orissa), Mahaar Naachni (Maharashtra), Thippa Ragi (Tamil Nadu).

Action: Used for biliary disorders. In Vietnamese traditional medicine, a decoction of the whole plant is used as stomachic, diuretic, febrifuge, and in sprains.

Aerial parts contain vitexin, 3-O- beta-D-glucopyranosyl-beta-sitosterol and its 6'-O-palmitoyl derivatives. of intoxication. Used for abdominal pains, nausea, bleeding nose. Fresh plants from Uttaranchal gave 0.4% essential oil having dehydroelsholtzia ketone 88.7% as the main constituent, followed by humulene 2.4% and caryophyllene 0.9% (the oil composition of the species which grow in Japan and Kashmir is different.)

Plant contains linarin, apigenin and 7-O-glucosides of apigenin and lute- olin.

The Japanese species, used for hangovers, gave compounds including tri- terpenoids, steroids and flavonoids.

Elsholtzia blenda Benth., synonym Perilla elata D. Don, is also equated with Ban-Tulasi. Major constituent of the essential oil is geranyl acetate. Other constituents are p-cymene, sa- binene, borneol, geraniol, linalyl acetate, fernesol, limonene, linalool, cit- ronellol, thymol and nerolidol.... eleusine indica

Enicostemma Littorale

auct. non-Bl.

Synonym: E. hyssopifolium (Willd) I. C. Verdoorn. E. axillare (Lam.) Raynal. Exacum hyssopifolium Willd. Adenema hyssopifolium G. Don.

Family: Gentianaceae.

Habitat: Throughout India, from Punjab and Gangetic Plain to Kanyakumari up to 500 m.

English: Indian Gentian.

Ayurvedic: Naagjhvaa, Maamajjaka, Naahi, Tikshnapatra.

Unani: Naai, Naahi.

Siddha/Tamil: Vellargu.

Folk: Chhotaa Chirayataa.

Action: Bitter tonic, carminative, blood purifier, antirheumatic, anti-inflammatory, antipsychotic, anthelmintic, cardiostimulant.

The plant is used as a substitute for Swertia chirayita, and is reported to be effective against malaria. The plant contains ophelic acid which is also present in chiretta as a hydrolytic product of chiratin. The root extract showed antimalarial activity both in vitro and in vivo.

Whole plant gave alkaloids—gen- tianine, erythrocentaurin, enicoflavine and gentiocrucine; flavonoids—api- genin, genkwanin iso-vitaxin, swer- tisin, saponarin and 5-O-glucoside derivatives of sylwertisin and isoswer- tisin; glucosides—swertiamarin, a tri- terpene betulin. Swertisiode exhibited hypotensive activity.

The plant extracts inhibited carrage- enan-induced oedema and its anti- inflammatory activity was found comparable to that of hydrocortisone.

Enicostema verticellatum Blume, the smallar var. ofKiryaata, is also equated with Vellargu (Siddha/Tamil).

Dosage: Whole plant—3-5 g powder; 50-100 ml decoction. (CCRAS.)... enicostemma littorale

Entada Scandens

auct. non-Benth.

Synonym: E. phaseoloides Merrill. E. pursaetha DC. Mimosa entada Linn.

Family: Momosaceae.

Habitat: Eastern Himalayas, hills of Bihar, Orissa and South India.

English: Garbee Bean, Mackay Bean, Elephant Creeper.

Ayurvedic: Gil.

Siddha/Tamil: Chillu, Vattavalli.

Folk: Gil-gaachh.

Action: Seed—carminative, anodyne, spasmolytic bechic, anti-inflammatory, anthelmintic, antiperiodic. Used in liver complaints, glandular swellings, debility, skin diseases. The seed, stems and bark are poisonous. A paste of the seeds is applied locally for inflammatory glandular swellings. The juice of wood and bark is used as an external application for ulcers. The leaves are reported to be free from the toxic saponins. After soaking in water and roasting toxic principles can be removed from the white kernels of the seeds.

The seeds gave saponins of entagenic acid; a triterpenoid glucoside entanin; beta-sitosterol, alpha-amyrin, querce- tin, gallic acid, cyamidin chloride, lu- peol and a saponin mixture which gave prosapogenin A. Entanin exhibits anti- tumour activity. It inhibits Walker 256 tumours in rats without deaths.

Entadamide A (the sulphur-containing amide from the seed) is a 5-lipo-xygenase inhibitor and is found to be effective in the treatment of bronchial asthma. The bark is used for hair wash.

Entagenic acid, a sapogenin of entada saponin IV, imparts antifungal activity to the bark.... entada scandens

Eruca Sativa

Mill.

Family: Cruciferae; Brassicaceae.

Habitat: Cultivated in Uttar Pradesh, Punjab, Delhi and Madhya Pradesh.

English: Rocket-Salad.

Ayurvedic: Tuvari, Tuvarikaa, Shveta-sursaa, Bhuutaghna, Darad- harsha, Siddaartha.

Unani: Jirjeer, Taraamiraa.

Folk: Safed Sarson.

Action: Tender leaf—stimulant, stomachic, diuretic, antiscorbutic, rubefacient. Seed—vesicant, antibacterial.

Seeds and fresh plant gave glu- coerucin (4-methylthiobutyl glucosi- nolate); leaves yielded iso-rhamnetin- 3-glucoside and iso-rhamnetin. The volatile oil of the seeds contains isoth- iocyanate derivatives. The oil at 0.004 and 0.008 ml/kg exhibits diuretic activity. The ethanolic extract of the seeds is diuretic at 20 and 40 mg/kg Seeds are used to induce vomiting in place of ipecac.

Crude juice of the plant inhibited E. coli, S. typhi and B. subttis.

For eating purposes, the plant should be gathered before flowering; for medicinal use when in flower.... eruca sativa

Euonymus Tingens

Wall.

Family: Celastraceae.

Habitat: Tropical Himalayas from Simla to Bhutan between 2,150 and 3,200 m, and in Assam.

English: Spindle Wood, Wahoo. (Euonymus atropurpureus, found in Eastern and Central USA and Canada, is equated with Wahoo and Spindle tree.

Ayurvedic: Bhillotaka.

Folk: Chopra, Mermahaul, Kunku, Barphali.

Action: Cholagogue, laxative, diuretic, circulatory stimulant. Used for constipation, torpidity of liver, gall bladder disorders, jaundice and dyspepsia. Bark is used in diseases of the eye.

Key application: Bark—as laxative.

(The British Herbal Pharmacopoeia.)

The plant yielded triterpenes—epi- friedelinol, taraxerol, dulcitol, pris- timerin and tingenins A and B. Pris- timerin exhibited antitumour activity.

Only bark and root bark is used medicinally. The seeds are poisonous.

Toxic constituents of E. atropur- pureus are furan-a-carboxylic acid; d- phenyl-glucosone (sterol glucoside); euatroside; euatromonoside (steroid glycosides). (Francis Brinker.)... euonymus tingens

Euphrasia Simplex

D. Don.

Synonym: E. officinalis Linn.

Family: Scrophulariaceae.

Habitat: The Temperate Himalaya from Kashmir to Sikkim, from 1,350 to 4,000 m.

English: Eyebright.

Action: Plant—astringent, antiallergic, bechic, anticatarrhal.

Key application: Externally as lotions, eye-baths, poultices, for eye complaints associated with inflammatory conditions, and as a preventive measure against mucus of the eyes, "glued" and inflammed eyes. (Traditional uses mentioned by German Comission E.)

Orally, Eyebright is used to treat allergies, common cold, bronchial conditions and sinusitis. Ophthalmic application is not recommended. Eye- bright has been used in a British herbal tobacco product, which was smoked for cold and chronic bronchial conditions.

Aerial parts showed presence of phenol, carboxylic acid, flavones and methyl flavone derivatives. Plant gave quercetin glucoside, diosmetin, kaem- pferol, caffeic and ferulic acids, stig- masterol and beta-sitosterol. Iridoid glycosides, including aucubin, are also present. Tannins include both condensed and hydrolysable gallic acid type.... euphrasia simplex

Feronia Limonia

(Linn.) Swingle.

Synonym: F. elephantum Corr.

Family: Rutaceae.

Habitat: Indigenous to South India; cultivated throughout the plains of India up to 500 m in the western Himalaya.

English: Wood Apple.

Ayurvedic: Kapittha, Dadhittha, Dadhiphala, Surabhichhada, Dantshatha, Kapipriya.

Unani: Kuvet.

Siddha/Tamil: Vilamaram, Vilangai, Narivila.

Folk: Kaith.

Action: Fruit—antiscorbutic, carminative, stimulates the digestive system bark. Pulp is included in a paste to tone the breast. Leaves— astringent; used for indigestion, flatulence, diarrhoea, dysentery and haemorrhoids.

Unripe fruit—prescribed in sprue, malabsorption syndrome. (The Ayurvedic Pharmacopoeia of India.)

The leaves and stem bark contain the coumarins, luvangetin, xanthotoxin and limonin and the steroids, sitosterol and sitosterol-O-beta-D-glucoside.

Antifungal compounds, psoralene from stem bark; xanthotoxin and os- thenol from root bark and 2,6-dimeth- oxybenzo-quinone from the fruit shell are reported. Roots contain xanthotoxin and bergapten, used for the treatment of leucoderma, characterized by vitiligo.

Dosage: Dried pulp of mature fruit—1-3 g powder. (API Vol. II.)... feronia limonia

Ficus Benghalensis

Linn.

Family: Moraceae.

Habitat: Sub-Himalayan tract and Peninsular India. Planted along roadsides, and in gardens.

English: Banyan tree.

Ayurvedic: Vata, Nyagrodha, Bahupaada, Dhruv.

Unani: Bargad, Darakht-e-Reesh.

Siddha/Tamil: Aalamaram.

Action: Infusion of bark—used in diabetes, dysentery, and in seminal weakness, leucorrhoea, menorrhagia, nervous disorders, erysipelas, burning sensation. Milky juice and seeds—applied topically to sores, ulcers, cracked soles of the feet, rheumatic inflammations. Buds—a decoction in milk is given in haemorrhages. Aerial roots— antiemetic, topically applied to pimples. Leaves—a paste is applied externally to abscesses and wounds for promoting suppuration.

Along with other therapeutic applications, The Ayurvedic Pharmacopoeia of India recommends the aerial root in lipid disorders.

Phytosterolin, isolated from the roots, given orally to fasting rabbits at a dose of 25 mg/kg, produced maximum fall in blood sugar level equivalent to 81% of the tolbutamide standard after 4 h. The root bark showed antidiabetic activity in pituitary diabetes and alloxan-induced diabetes.

The alcoholic extract of the stem bark also exhibited antidiabetic activity on alloxan-induced diabetes in albino rats, and brought down the level of serum cholesterol and blood urea. This activity is attributed to a glucoside, bengalenoside and the flavonoid glycosides, leucocyanidin and leucopelargonidin. Bengalenoside is half as potent as tolbutamide. The leucopelargonidin glycoside is practically nontoxic and may be useful in controlling diabetes with hyperlipi- demia. The leucocyanidin, when combined with a low dose of insulin, not only equalled in response the effects brought about by a double dose of insulin, but also excelled in amelioration of serum cholesterol and triglycerides.

(Additional references: Indian J Physiol Pharmacol, 1975, 19(4), 218220; J Ethnopharmacol, 1989, 26(1), 155; Indian J Physiol Pharmacol, 1994, 38(3), 220-222.)... ficus benghalensis

Ficus Religiosa

Linn.

Family: Moraceae.

Habitat: Sub-Himalayan tracts, West Bengal, Central and South India; planted throughout India as an avenue tree.

English: Peepal, Bot-tree.

Ayurvedic: Ashvattha, Bodhidru, Bodhivrkisha, Sebya, Chalapa- tra, Gajabhaksha, Kshiradruma, Peeppal.

Unani: Peepal.

Siddha/Tamil: Arasu, Ashvatham.

Action: Bark—astringent, antiseptic, alterative, laxative, haemostatic, vaginal disinfectant (used in diabetes, diarrhoea, leucorrhoea, menorrhagia, nervous disorders; also in skin diseases.) Applied externally on unhealthy ulcers and wounds. Leaves and twigs— laxative.

The bark contains beta-sitosteryl-D- glucoside. Vitamin K, n-octacosanol, methyl oleanolate, lanosterol, stigmas- terol, lupen-3-one are reported from the stem bark.

A hypoglycaemic response is reported for beta-sitosterol-D-glucoside obtained from the bark.

Aerial roots are given to women, also used in prescriptions, for inducing conception. The dried fruits are used as a uterine tonic.

The fruits contain 4.9% protein having the essential amino acids, isoleu- cine and phenylalanine. The chloroform extract of fruits exhibited anti- tumour and antibacterial activities in bioassays.

Various plant parts are included in formulations used for menorrha- gia, metrorrhagia, blood dysentery, bleeding piles, haematuria and haemorrhages.

Dosage: Bark, fruit—50-100 ml decoction. (CCRAS.)... ficus religiosa

Fraxinus Griffithii

Clarke.

Family: Oleaceae.

Habitat: Arunachal Pradesh (Mishmi Hills).

Action: Toxic to CNS.

The extract of the bark and leaves are used as an adulterant of illegal opium and are sold in the black market in certain areas in Indonesia.

The bark contains an iridoid glu- coside, ligstroside, and the phenolic glucosides, syringin and sinapaldehyde glucoside.

Family: Oleaceae.

Habitat: F. excelsior Linn.—Great Britain, Europe and North America. F. hookery—Western Himalaya at 2,700-3,350 m.

English: European Ash, Weeping Ash.

Folk: Kum, Sum, Hum, Sinnun (Punjab, Kashmir).

Action: F. excelsior—laxative, antiinflammatory, febrifuge. The bark and leaves are used for arthritis and rheumatism.

The herb gave coumarin derivatives, including fraxin, fraxetin and fraxinol; flavonoids based on aesculetin, including aescin, also rutin and quercetin. A coumarin derivative is actively diuretic.

A saccharine exudate, manna, consisting principally of mannitol, is obtained by incising the stem barks of some Fraxinus sp. found in India. The manna of commerce is derived from F. ornus. F. hookery (bark)—astringent, febrifuge, bitter tonic. Leaves—cathartic.

Ash Bark is used, in decoction, in the treatment of intermittent fever and ague, as a substitute for Peruvian bark. Also used for treating obstructions of the liver and spleen and in rheumatism and arthritic affections.

Preparations of European Ash Bark showed an analgesic, anti-exudative and antiphlogistic action. (German Commission E.)

Habitat: Indigenous to the coasts of the Mediterranean from Spain to Smyrna.

English: Flake Manna.

Unani: Turanjeen.

Action: A children's laxative. Usually prescribed with other purgatives. (Not to be used in the presence of ileus.)

Key application: In constipation where an easier elimination and a soft stool are desirable; in animents such as anal fissures, haemorrhoids and post-rectal and surgery. (German Commission E.)

The exudation contains 40-90% mannitol, 10-15% stachyose and man- notriose, glucose, fructose.... fraxinus griffithii

Galium Verum

Linn.

Habitat: Kashmir, Lahul and other west Himalayan regions, at altitude of 2,000-3,000 m

English: Lady's Bedstraw, Cheese Rennet.

Action: Herb—diuretic, used for kidney stone, gravel, gout. Used topically for poorly healing wounds.

The plant contains the iridoids including asperuloside and galioside; flavonoid glycosides; quercetin-3-glu- coside, quercetin-7-glucoside, quer- cetin-3-rutinoside, luteolin-7-gluco- side; anthraquinone derivatives, including alizarin, and large amounts of salicylic acid. Its high organic acid content causes curdling of milk. The root contain n-alkanes.... galium verum

Garcinia Indica

Choisy.

Synonym: G. Purpurea Roxb.

Family: Guttiferae; Clusiaceae.

Habitat: Evergreen forests of Western Ghats from Konkan southwards and in Goa. Also cultivated in southern districts of Maharashtra and on lower slopes of Nilgiris.

English: Kokam Butter tree, Mangosteen Oil tree.

Ayurvedic: Vrkshaamla, Tintidika, Chukra, Amlavrkshak, Kokam, Amsula.

Siddha/Tamil: Murgal.

Folk: Kokam.

Action: Fruit—antiscorbutic, cholagogue, cooling, antibilious, emollient and demulcent. A syrup from the fruit juice is given in bilious affections. Bark—astringent, Oil or Kokam Butter—used for dysentery and diarrhoea with mucus. Applied externally to ulcerations, fissures of lips, chapped skin and skin diseases.

The fruit rind contain a polyiso- prenylated phenolic pigment, garci- nol and its isomer isogarcinol, along with (-)-hydroxycitric acid, cyanidin- 3-glucoside and cyanidin-3-sambubio- side. L-leucine and DNP-L-leucine hy- drochloride have been reported from the leaves.

EtOH (50%) extract of aerial parts exhibited semen coagulant and CNS depressant activity.

Kokum butter contains fatty acids— palmtic 2.0, stearic 57.5, oleic 39.0, linoleic 1.3 and others 0.2%.

Dosage: Fruit—10-20 ml juice; root bark—40-80 ml decoction. (CCRAS.)... garcinia indica

Grewia Asiatica

auct. non L. Synonym: G. subinaequalis DC.Family: Tiliaceae.

Habitat: Extensively cultivated in India.Ayurvedic: Parushaka, Parusha.Unani: Phaalsaa.Siddha/Tamil: Palisa, Thadachi.

Action: Fruit—stomachic, astringent, cooling. Bark—demulcent. Root bark—antirheumatic. Leaf— used in pastular eruptions.The bark contains taraxasterol, beta- sitosterol, erythrodiol; lupeol, betulin, lupenone, friedelin; alpha-amyrin. The heartwood gave beta-sitosterol. Quer- cetin, kaempferol and their glycosides were also obtained from the leaves.Ripe fruits are rich in vitamin A and C; threonine, phosphoserine, serine and taurine are the dominant amino acids in the juice. The fruits also contain sodium 22, potassium 1250, and calcium 260 ppm Fruits also gave pelargonidin-3, 5- diglucoside, quercetin, quercetin-3-0- beta-D-glucoside, naringenin and 7-0- beta-D-glucoside.The stem bark exhibited antifertility activity.Dosage: Ripe fruit—20-50 ml juice. (CCRAS.)... grewia asiatica

Gymnosporia Spinosa

(Forsk.) Fiori.

Synonym: G. Montana (Roth) Benth.

Maytenus senegulensis Exell. M. emarginata Ding Hou.

Family: Celastraceae.

Habitat: Throughout the drier parts of India.

Ayurvedic: Vikankata (substitute) Sruva-Vrksha (substitute), Vyaaghrapaadi.

Siddha/Tamil: Kattangi, Nandunarai, Valuluvai.

Folk: Baikal.

Action: Plant—antispasmodic. Root—used in gastroenteritis and dysentery.

The bark is ground to a paste and applied with mustard oil to kill lice in the hair. A decoction of leafy twigs is used as a mouth wash to relieve toothache.

The leaves contain celacinnine, al- pha-and beta-amyrin, beta-amyrone, beta-sitosterol and its 3'-O-glucoside and kaempferol. The extracts of the plant show cytotoxic effect on some cancers. An ointment, prepared by mixing leaf ash and purified butter, is used for sores.... gymnosporia spinosa

Hemidictyum Ceterach

L.

Synonym: Ceterach officinarum Willd. Asplenium ceterach L.

Family: Athyriaceae, Polypodiaceae.

Habitat: Western Himalaya, from Kashmir to Garhwal, up to 3,000 m.

Action: Fern—diuretic, astringent; used for diseases of the urinary tract, infirmities of spleen, also for treating jaundice.

The plant contains caffeic acid, neo- hesperidin, kaempferol-3, 7-digluco- side, chlorogenic acid and quercetol- 3-glucoside. The leaves gave methyl esters of the acids—myristic, palmitic,

Synonym: H. nepalense D. Don. H. lanatum Michx.

Family: Umbelliferae; Apiaceae.

Habitat: Chamba, Kulu, Jammu & Kashmir, Bushahr, Garhwal and Kumaon Hills.

English: Cowparsnip.

Folk: Kaindal (Kashmir), Gandhraayana (Garhwal).

Action: Fruit—stimulant, nervine tonic, spasmolytic. Heraclenin (active principle)—hypoprothrom- binaemic.

Essential oil from the fruits is moderately antimicrobial.

Furanocoumarins present in the whole fruit and leaves are psoralen, xanthotoxin and bergapten. Roots also contain furanocoumarins.

The fruits of H. concanense Dalz. contain a coumarin which is effective against dermatophytosis. The fruits of H. regins Wall. ex DC. are used for cough and bronchitis, also for urinary concretions in Siddha medicine. H. thomsoni C. B. Clarke (Kashmir and Himachal Pradesh) also contains a coumarin; the fruit showed nonspecific spasmolytic activity equipotent to papaverine.... hemidictyum ceterach

Glory Lily

Gloriosa superba

Liliaceae

San: Langali, Visalya, Agnishika,Shakrapushpi, Garbhaghatini

Hin: Kalihari

Mal: Menthonni

Tam: Akkinichilam

Pan: Kariari

Guj: Dudhiya vachnag

Kan: Nangulika Mar: Nagakaria

Ben: Bishalanguli Ori: Dangogahana

Tel: Adavinabhi

Importance: Glory lily is a glabrous herbaceous climber which yields different types of troplone alkaloids of medicinal importance. The major alkaloids are colchicine , 3-demethyl colchicine and colchicoside. There is another alkaloid gloriosine which promises to be even more effective than colchicine in plant breeding for inducing polyploidy. The genus has importance in the ornamental horticulture due to its bright flowers and wiry climbing stem.

The roots and rhizomes are used in traditional system of medicine. Its abortifacient and antipyretic properties have been mentioned in ancient classics “Charaka”. The name Garbhaghatini is due to this abortifacient activity. They are useful in the treatment of inflammations, ulcers, scrofula, hemorrhoids, pruritus, dyspepsia, helminthiasis, flatulence, intermittent fevers and debility. The root is given internally as an effective antidote against cobra poison. A paste of the root is also used as an anodyne; applications in bites of poisonous insects, snake bites, scorpion sting, parasitic skin diseases and leprosy (Nadkarni,1954; Chaudhuri and Thakur; 1994).

Distribution: The plant is distributed throughout tropical India upto an altitude of 2500m and in Andaman islands. It is also cultivated in tropical and South Africa, Madagaskar, Indonesia and Malasia. It is reported to be cultivated in some parts of Europe. In India it was cultivated in RRL, Jammu in 1960s. Recently it was taken up by Indian Council of Agricultural Research(ICAR). Cultivation of the plant is mostly confined to the Southern states of India besides its collection from wild sources.

Botany: Gloriosa superba Linn. belongs to Liliaceae family. It is a glabrous climbing herb with tuberous root stock grows over hedges and small trees. Stem is 6m long which grows to a height of 1.2-1.5m before the stem branches. Leaves are simple, alternate or whorled, sessile, ovate-lanceolate, 17x4.5cm, tip elongating into a spirally coiled tendril, base cordate and margin entire. Flowers are large in terminal racemes; perianth segments 6, linear, flexuosus and deflexed, basal half bright yellow, upper half red; stamens 6; ovary glabrous, 3-celled. Fruits are capsules, linear-oblong, upto 6.8cm long, 3 equal lobes, one or two lobes shorter in malformed fruits; green dried to pale and then black colour, dehisced into three sections. Seeds are oval in shape, testa spongy, embryo cylindric, 30-150 seeds per capsule, pale orange attached to the sutures. Tubers are cylindric, large, simple, ‘V’ shaped with the two limps equal or unequal in lenth pointed towards end brownish externally and yellowish internally. (Narain, 1977)

Agrotechnology: This is a rainy season plant and sprouts well in warm, humid and tropical conditions. It should be grown in sun as the plants in shade become weedy and thin and move towards light. G. superba is a shallow rooted plant and grows well in a variety of soils either clay or sand through out India. It grows well in a light porous soil with good drainage. For vigorous growth, greater blooms and strong tuber, a mixture of soil, sand and compost manure is recommended. The propagation is mainly by tubers, by division of rhizomes. Seeds remain dormant for 6-9 months and due to hard seed coat, about 20-30 days are required for germination and seeds may take 3-4 years before it matures to flower. Treatment of seeds by gibberellin(1-3 ppm) resulted in higher yield of colchicine in the plant and higher production of tubers. In tissue culture, young sprouts are cultured on Murashige and Skoog’s medium (Msb) supplemented with kinetin (1-4 mg/l). Direct regeneration of the explants are obtained.

The seeds and rhizomes are sown usually in the last week of June to mid July. The rhizomes are planted by splitting carefully into two from their ‘V’ shaped joints (two buds being at the extreme end of each rhizome) in lines 20cm apart at a distance of 20cm (while seeds are sown in lines at a distance of 4-6cm apart). They are watered regularly when the plants are growing. After green shoots appear 2-3 showers are weekly. The irradiation of the plant at 42% natural sunlight intensity increased the production of tuber and colchicine. They usually takes 6-10 weeks to flower after sprouting and then set on fruits. The fruits ripen at the end of October and after that aerial shoot eventually dies, leaving the fleshy tubers underground. The tubers are dug out with great care. An individual plant produces 50g tubers on an average. The average yield is approximately 4000-5000kg of rhizomes and 1000 kg of seed per hectare. The content of colchicine is usually 0.358% and 1.013% in tubers and seeds, respectively.

Post harvest technology: Lixivation of the material is done with 70% ethyl alcohol. Concentrated under vacuum to one third of its volume and extracted with chloroform for colchicine and related substances-concentration of the aqueous phase to syrup which is extracted 6-8 times with a mixture of CHCl3 - alcohol (4:1) to yield colchicoside.

Properties and activity: The flowers, leaves and tubers contain colchicine, superbin, N-formyl deacetyl colchicine, demethyl colochicine and lumicolchicine. Tubers also contain gloriosine. Leaves in addition, contain chelidonic acid, 2-hydroxy 6-methoxy benzoic acid and -sitosterol glucoside. Colchicine, demethyl colchicine and colchicoside have been reported from seeds. Rhizome is oxytocic, anticancerous, antimalarial, stomachic, purgative, cholagogue, anthelmintic, alterative, febrifuge and antileprotic. Leaf is antiasthmatic and antiinflammatory. Root shows antigonorrhoeic and antibiotic activity. This plant has poisonous effect to enviroment and livestock. The toxic properties are due to presence of alkaloids chiefly colchicine (Clewer et al, 1915).... glory lily

Greater Ammi

Ammi majus

Apiaceae

Importance: Greater Ammi, also known as Bishop’s weed or Honey plant is an annual or biennial herb which is extensively used in the treatment of leucoderma (vitiligo) and psoriasis. The compounds responsible for this are reported to be furocoumarins like ammoidin (xanthotoxin), ammidin (imperatorin) and majudin (bergapten) present in the seed. Xanthotoxin is marketed under the trade name “Ox soralen” which is administered orally in doses of 50 mg t.d. or applied externally as 1% liniment followed by exposure of affected areas to sunlight or UV light for 2 hours. It is also used in “Suntan lotion”. Meladinine is a by-product of Ammi majus processing, containing both xanthotoxin and imperatorin sold in various formulations increases pigmentation of normal skin and induces repigmentation in vitiligo. Imperatorin has antitumour activity. Fruit or seed causes photosensitization in fouls and sheep.

Distribution: The plant is indigenous to Egypt and it grows in the Nile Valley, especially in Behira and Fayoom. It is also found in the basin of the Mediterranean Sea, in Syria, Palestine, Abyssinia, West Africa, in some regions of Iran and the mountains of Kohaz (Ramadan, 1982). It grows wild in the wild state in Abbottabad, Mainwali, Mahran and is cultivated in Pakistan. The crop was introduced to India in the Forest Research Institute, Dehra Dun, in 1955 through the courtesy of UNESCO. Since then, the crop has been grown for its medicinal fruit in several places in Uttar Pradesh, Gujarat, Kashmir and Tamil Nadu.

Botany: Ammi majus Linn. belongs to the family Apiaceae (Umbelliferae). A. visnaga is another related species of medicinal importance. A. majus is an annual or beinnial herb growing to a height of 80 to 120 cm. It has a long tap root, solid erect stem, decompound leaves, light green alternate, variously pinnately divided, having lanceolate to oval segments. Inflorescence is axillary and terminal compound umbels with white flowers. The fruits are ribbed, ellipsoid, green to greenish brown when immature, turning reddish brown at maturity and having a characteristic terebinthinate odour becoming strong on crushing with extremely pungent and slightly bitter taste.

Agrotechnology: Ammi is relatively cold loving and it comes up well under subtropical and temperate conditions. It does not prefer heavy rainfall. Though the plant is biennial it behaves as an annual under cultivation in India. A mild cool climate in the early stages of crop growth and a warm dry weather at maturity is ideal. It is cultivated as a winter annual crop in rabi season. A wide variety of soils from sandy loam to clay loam are suitable. However, a well drained loamy soil is the best. Waterlogged soils are not good. Being a hardy crop, it thrives on poor and degraded soils.

The plant is seed propagated. Seeds germinate within 10-12 days of sowing. The best time of sowing is October and the crop duration is 160-170 days in north India. Crop sown later gives lower yield. The crop can be raised either by direct sowing of seed or by raising a nursery and then transplanting the crop. Seed rate is 2 kg/ha. The land is brought to a fine tilth by repeated ploughing and harrowing. Ridges and furrows are then formed at 45-60 cm spacing. Well decomposed FYM at 10-15 t/ha and basal fertilisers are incorporated in the furrows. Seeds being very small are mixed with fine sand or soil, sown in furrows and covered lightly with a thin layer of soil. A fertilizer dose of 80:30:30 kg N, P2O5 and K2O/ha is generally recommended for the crop while 150:40:40 kg/ha is suggested in poor soils for better yields. The furocoumarin content of Ammi majus is increased by N fertiliser and the N use efficiency increases with split application of N at sowing, branching and at flowering. For obtaining high yields it is essential to give one or two hoeings during November to February which keeps down the weeds. If winter rains fail, one irrigation is essential during November to January. As the harvesting season is spread over a long period of time, two irrigations during March and April meets the requirements of the crop (Chadha and Gupta, 1995).

White ants and cut worms are reported to attack the crop which can be controlled by spraying the crop with 40g carbaryl in 10 l of water. Damping off and powdery mildew are the common diseases of the crop. Seed treatment with organomercuric compounds is recommended for damping off. To control powdery mildew the crop is to be sprayed with 30g wettable sulphur in 10 l of water whenever noticed.

The crop flowers in February. Flowering and maturity of seed is spread over a long period of two months. The primary umbels and the early maturing secondary umbels are the major contributors to yield. A little delay in harvesting results in the shattering of the seed which is the main constraint in the commercial cultivation of the crop and the main reason for low yields in India. Sobti et al (1978) have reported increased yield by 50 - 60% by the application of planofix at 5 ppm at flower initiation and fruit formation stages. The optimum time of harvest is the mature green stage of the fruit in view of the reduced losses due to shattering and maximum contents of furocoumarins. The primary umbels mature first within 35-45 days. These are harvested at an interval of 2-4 days. Later, the early appearing secondary umbels are harvested. Afterwards, the entire crop is harvested, stored for a couple of days and then threshed to separate the seeds. The seed yield is 900-1200 kg/ha.

Postharvest technology: The processing of seed involves solvent extraction of powdered seeds, followed by chilling and liquid extraction and chromatographic separation after treatment with alcoholic HCl. Bergapten, xanthotoxin and xanthotoxol can be separated. Xanthotoxol can be methylated and the total xanthotoxin can be purified by charcoal treatment in acetone or alcohol.

Properties and activity: Ammi majus fruit contains amorphous glucoside 1%, tannin 0.45%, oleoresin 4.76%, acrid oil 3.2%, fixed oil 12.92%, proteins 13.83% and cellulose 22.4%. This is one of the richest sources of linear furocoumarins. Ivie (1978) evaluated the furocoumarin chemistry of taxa Ammi majus and reported the presence of xanthotoxin, bergapten, imperatorin, oxypencedanin, heraclenin, sexalin, pabulenol and many other compounds. Furocoumarins have bactericidal, fungicidal, insecticidal, larvicidal, moluscicidal, nematicidal, ovicidal, viricidal and herbicidal activities (Duke, 1988).... greater ammi

Hibiscus Abelmoschus

Linn.

Synonym: Abelmoschus moschatus Medic.

Family: Malvaceae.

Habitat: Throughout the warmer parts and hilly regions of India; also cultivated.

English: Musk Seed, Muskmallow, Ambette Seed.

Ayurvedic: Lataakasturi, Lataakas- turikaa, Kattaphala, Katuka.

Unani: Mushkdaanaa.

Siddha/Tamil: Kasturi-vendai.

Action: Seeds—diuretic, antispas- modic, stomachic, nervine (nervous debility, hysteria and other nervous disorders). Used externally for skin diseases and itch. Mucilage made from the root and leaves is prescribed in venereal diseases, urinary discharges and painful micturition. Seeds, steeped in water, are used for asthma, cold, flu.

Fatty oil of seeds contains phospholipids—alpha cephalin, phosphatidyl- serine and its plasmalogen and phos- phatidylcholine plasmalogen. Absolute contains farnesol and ambrettolic acid lactones.

The seeds contain chiefly 2-trans, 6-trans-farnesyl acetate, 2-cis, 6-trans farnesyl acetate and ambrettolide. The leaves contain beta-sitosterol and its beta-D-glucoside.

Dosage: Seed—2-4 g powder. (API Vol. IV.)... hibiscus abelmoschus

Hibiscus Cannabinus

Linn.

Family: Malvaceae.

Habitat: Native to tropical America and Africa; cultivated in West Bengal, Andhra Pradesh, Assam, Uttar Pradesh, Madhya Pradesh, Tamil Nadu, Bihar and Punjab.

English: Bimlipatam Jute, Kenaf, Mesta, Deccan Hemp.

Siddha/Tamil: Pulichhai, Pulimanji, Kasini.

Folk: Patsan, Pitwaa. Ambaadi (Maharashtra).

Action: Seed—nervine tonic, analgesic. Leaf—purgative. The juice of flowers, mixed with sugar and black pepper, is given for biliousness.

The leaves contain flavonoids, including rutin and isoquercitrin; kaem- pferol; polyphenols. The flowers gave myricetin glucoside; the root contains polyphenols, also proanthocyanidins. The seeds gave phosphonolipids.... hibiscus cannabinus

Hiptage Benghalensis

Kurz.

Synonym: H. madablota Gaertn.

Family: Malpighiaceae.

Habitat: Throughout the warmer parts of Maharashtra, Konkan, Karnataka and other parts of India.

Ayurvedic: Atimukta, Atimuktaka, Maadhavi, Vaasanti, Pundrika, Mandaka, Vimukta, Kaamu- ka.

Siddha/Tamil: Madhavi, Vasanda- gala-malligai.

Action: Kernel of seeds is prescribed for reducing abdominal girth (obesity). Leaves—used in chronic rheumatism, asthma and skin diseases. Bark—used in bronchial asthma.

The stem and its bark contain friede- lin, epi-friedelinol, octacosanol, alpha- amyrin, beta-sitosterol and its beta-D- glucoside. The root bark gave a nitrogenous glucoside, hiptagin, identical with endecaphyllin and a glucosyl xanthone, mangiferin.

Dosage: Fruit, seed, root—powder 3-5 g; paste 5-10 g. (CCRAS.)... hiptage benghalensis

Holarrhena Antidysenterica

(Linn.) Wall.

Synonym: H. pubescens (Buch.- Ham.) Wall. ex G. Don.

Family: Apocynaceae.

Habitat: The tropical Himalayas, going up to an altitude of 1,100 m. Also found throughout many forests of India, in Travancore, Assam and Uttar Pradesh.

English: Easter tree, Ivory tree, Tellicherry Bark.

Ayurvedic: Kutaja, Girimallikaa, Kaalinga, Kalingaka, Indravrik- sha, Shakra, Vatsa, Vatsaka, Shakraahvya. Indrayava, Indrabija, Vatsabija (seed). Kurchi (bark).

Unani: Inderjo talkh, Teewaaj-e- Khataai.

Siddha/Tamil: Kudasappaalai-pattai, -vidai (bark, seed).

Action: Root and bark—used in amoebic dysentery. Bark—astringent, anthelmintic, amoebicidal, diuretic. Used in colic, dyspepsia, piles, diseases of the skin and spleen. Seed—antibilious. Used for promoting conception, also for toning up vaginal tissues after delivery.

The bark contains the alkaloids, regholarrhenine-A, -B, -C, -D, -E and -F; pubescine, norholadiene, pubes- cimine, kurchinin, kurchinine, kur- chinidine, holarrifine, holadiene, kurchilidine, kurchamide, kurcholes- sine, kurchessine, conessine, cones- simine and isoconessimine, and the steroidal compounds kurchinicin and holadyson.

The alkaloid conessine is used as a therapeutic drug for the treatment of dysentery and helminthic disorders. Conessine and conimine inhibited the growth of Shigella sonnei, S. flexneri and Salmonella enteritidis strains in vitro. In chronic amoebiasis, Bi-iodide compound of total alkaloids, given orally, compare favourably with emetine Bi-iodide.

The plant possesses potent immuno- stimulant property.

The Kurchi seeds are sold as a substitute for Strophanthus sp. seeds in Indian market. (Seeds of Strophanthus sp. contain a toxic glucoside, strophan- thin, and are poisonous.)

Dosage: Stem bark—20-30 g for decoction. (API Vol. I); seed—3- 6 g powder; 20-30 g for decoction. (API Vol. III.)... holarrhena antidysenterica

Hypoglycaemic Agents

These oral agents reduce the excessive amounts of GLUCOSE in the blood (HYPERGLYCAEMIA) in people with type 2 (INSULIN-resistant) diabetes (see DIABETES MELLITUS). Although the various drugs act di?erently, most depend on a supply of endogenous (secreted by the PANCREAS) insulin. Thus they are of no value in treating patients with type 1 diabetes (insulin-dependent diabetes mellitus (IDDM), in which the pancreas produces little or no insulin and the patient’s condition is stabilised using insulin injections). The traditional oral hypoglycaemic drugs have been the sulphonylureas and biguanides; new agents are now available – for example, thiazolidine-diones (insulin-enhancing agents) and alpha-glucosidase inhibitors, which delay the digestion of CARBOHYDRATE and the absorption of glucose. Hypoglycaemic agents should not be prescribed until diabetic patients have been shown not to respond adequately to at least three months’ restriction of energy and carbohydrate intake.

Sulphonylureas The main group of hypoglycaemic agents, these act on the beta cells to stimulate insulin release; consequently they are e?ective only when there is some residual pancreatic beta-cell activity (see INSULIN). They also act on peripheral tissues to increase sensitivity, although this is less important. All sulphonylureas may lead to HYPOGLYCAEMIA four hours or more after food, but this is relatively uncommon, and usually an indication of overdose.

There are several di?erent sulphonylureas; apart from some di?erences in their duration or action (and hence in their suitability for individual patients) there is little di?erence in their e?ectiveness. Only chlorpropamide has appreciably more side-effects – mainly because of its prolonged duration of action and consequent risk of hypoglycaemia. There is also the common and unpleasant chlorpropamide/ alcohol-?ush phenomenon when the patient takes alcohol. Selection of an individual sulphonylurea depends on the patient’s age and renal function, and often just on personal preference. Elderly patients are particularly prone to the risks of hypoglycaemia when long-acting drugs are used. In these patients chlorpropamide, and preferably glibenclamide, should be avoided and replaced by others such as gliclazide or tolbutamide.

These drugs may cause weight gain and are indicated only if poor control persists despite adequate attempts at dieting. They should not be used during breast feeding, and caution is necessary in the elderly and in those with renal or hepatic insu?ciency. They should also be avoided in porphyria (see PORPHYRIAS). During surgery and intercurrent illness (such as myocardial infarction, COMA, infection and trauma), insulin therapy should be temporarily substituted. Insulin is generally used during pregnancy and should be used in the presence of ketoacidosis.

Side-effects Chie?y gastrointestinal disturbances and headache; these are generally mild and infrequent. After drinking alcohol, chlorpropamide may cause facial ?ushing. It also may enhance the action of antidiuretic hormone (see VASOPRESSIN), very rarely causing HYPONATRAEMIA.

Sensitivity reactions are very rare, usually occurring in the ?rst six to eight weeks of therapy. They include transient rashes which rarely progress to erythema multiforme (see under ERYTHEMA) and exfoliate DERMATITIS, fever and jaundice; chlorpropamide may also occasionally result in photosensitivity. Rare blood disorders include THROMBOCYTOPENIA, AGRANULOCYTOSIS and aplastic ANAEMIA.

Biguanides Metformin, the only available member of this group, acts by reducing GLUCONEOGENESIS and by increasing peripheral utilisation of glucose. It can act only if there is some residual insulin activity, hence it is only of value in the treatment of non-insulin dependent (type 2) diabetics. It may be used alone or with a sulphonylurea, and is indicated when strict dieting and sulphonylurea treatment have failed to control the diabetes. It is particularly valuable in overweight patients, in whom it may be used ?rst. Metformin has several advantages: hypoglycaemia is not usually a problem; weight gain is uncommon; and plasma insulin levels are lowered. Gastrointestinal side-effects are initially common and persistent in some patients, especially when high doses are being taken. Lactic acidosis is a rarely seen hazard occurring in patients with renal impairment, in whom metformin should not be used.

Other antidiabetics Acarbose is an inhibitor of intestinal alpha glucosidases (enzymes that process GLUCOSIDES), delaying the digestion of starch and sucrose, and hence the increase in blood glucose concentrations after a meal containing carbohydrate. It has been introduced for the treatment of type 2 patients inadequately controlled by diet or diet with oral hypoglycaemics.

Guar gum, if taken in adequate doses, acts by delaying carbohydrate absorption, and therefore reducing the postprandial blood glucose levels. It is also used to relieve symptoms of the DUMPING SYNDROME.... hypoglycaemic agents

Ilex Aquifolium

Linn.

Family: Aquifolilaceae.

Habitat: Native to Europe; grown occasionally in gardens at hill stations.

English: English Holly, Common Holly.

Action: Leaves—diaphoretic, febrifuge. Used in catarrh, pleurisy, intermittent fever, smallpox and rheumatism. Also in jaundice. Berries—violently emetic and purgative; employed in dropsy. Powdered berries are used as astringent to check bleeding.

(Berries possess totally different qualities as compared to leaves.)

The plant contains ilicin (a bitter principle), ilexanthin, theobromine (only in the leaf) and caffeic acid. Alkaloid theobromine is used for asthma. In Greece, boiled leaves are used for treating enlarged prostate.

An extract of the plant caused a fatal drop in blood pressure in rats.

The ethanolic extract of the fruits yields cyanogenic glucosides.... ilex aquifolium

Indigofera Oblongifolia

Forsk Synonym: I. paucifolia Delile.Family: Fabaceae.

Habitat: Throughout greater parts of India.English: Wild Indigo, Mysore Panicled Indigo.Ayurvedic: Bana-Nila, Dill, Jhill.Unani: Vasmaa.Siddha/Tamil: Kattukkarchamathi.Folk: Jhil (Gujarat).

Action: Plant—antisyphilitic. All parts of the plant are found useful in enlargement of liver and spleen.The leaves gave apigenin 7-rhamno- glucoside, apigenin 7, 4'-diglucoside, kaempferol-3-neohesperidoside and rhoifolin, along with protocatechuic, p-coumaric, p-hydroxybenzoic, salicylic and vanillic acid.... indigofera oblongifolia

Ipomoea Bona-nox

Linn.

Synonym: I. alba Linn. Calonyction bona-nox Bojer. C. aculeatum (Linn.) House.

Family: Convolvulaceae.

Habitat: Throughout India.

English: Moon Flower.

Ayurvedic: Chandrakaanti, Gul- chaandani, Dudhiaa Kalami.

Siddha/Tamil: Naganamukkori.

Folk: Chaandani, Dudhiaa Kalami.

Action: Root bark—purgative. Leaves—used in filariasis.

The plant contains pentasaccharide glucoside of ethyl-ll-hydroxy hexade- canoate. The seeds contain alkaloids, ipomine, isoipomine, methoxyipo- mine, dimethoxyipomine, ipalkidini- um, ipalbidine and ipalbine.... ipomoea bona-nox

Ipomoea Nil

(Linn.) Roth

Synonym: Convolvulus bilobatus Roxb. Convolvulus nil Linn.

Family: Convolvulaceae.

Habitat: Throughout India; also occurs as a weed.

English: Pharbitis seeds.

Ayurvedic: Antah-kotarpushpi, Kaalaanjani (provisional synonym), Krishnabija, Kaalaadaanaa, Shyaamabija, Shankhani, Jhaara- maaricha.

Unani: Kaalaadaanaa.

Siddha/Tamil: Kaakkattan.

Action: Purgative and blood- purifier. A substitute for Jalap. Seeds—antifungal.

The seeds from Pakistan contain al- kaloids—lysergol, chanoclavine, pen- niclavine, isopenniclavine and elymo- clavine. Also contain 14.2% resin and glucosides.

Commercial samples of the drug contain 14-15% of crude resinous matter. Research has shown that glycosi- dal part of the resin is inert; the non- glycosidal resin (2% of the drug) causes copious purgation in doses of 250 mg. Besides the resinous matter, the seeds contain a fixed oil (12.4%) and small amounts of saponin, mucilage and tannin.

The flowers of the plant contains an- thocyanin pigments.

The plant extract exhibited hypogly- caemic activity in rats.

Dosage: Seed—3-6 g powder. (CCRAS.)

Synonym: I. hederacea auct., non- Jacq.... ipomoea nil

Ipomoea Purpurea

(Linn.) Roth.

Family: Convolvulaceae.

Habitat: Native of tropical America; found throughout greater part of India, grown in gardens.

English: Tall Morning-Glory.

Folk: Karakatiyaa (seeds).

Action: Purgative. Seed extract— antibacterial.

The stem contains a soft resin (4.8%), essential oil (0.08%) and tannin. The resin is the active principle, it contains ipuranol, which is identical with sitosterol glucoside, ipurolic acid, d- methyl acetic acid, hydroxylauric acid and glucose.... ipomoea purpurea

Jasminum Officinale

Linn. var. grandiflorum (L.) Kobuski.

Synonym: J. grandiflorum Linn.

Family: Oleaceae.

Habitat: North-Western Himalayas and Persia; cultivated in Kumaon, Uttar Pradesh, Rajasthan, Madhya Pradesh; in gardens throughout India.

English: Spanish Jasmine.

Ayurvedic: Jaati, Jaatikaa, Jaatimalli, Pravaaljaati, Saumanasyaayani, Sumanaa, Chetikaa, Hriddgandhaa, Maalati, Chameli.

Unani: Yaasmin.

Siddha/Tamil: Manmadabanam, Mullai, Padar-malligai, Pichi, Malli

Folk: Chameli.

Action: Flowers—calming and sedative, CNS depressant, astringent and mild anaesthetic. A syrup prepared from the flowers is used for coughs, hoarsenesses and other disorders of the chest. Plant—diuretic, anthelmintic, emmenagogue; used for healing chronic ulcers and skin diseases. Oil—externally relaxing.

Indian oil sample gave benzyl acetate 26.3, benzyl benzoate 19.2, phytol 10.6, jasmone 8.5, methyl jasmonate 6.3, linalool 5.4, geranyl linalool 3.5, eugenol 2.9, isophytyl acetate 2.7, and isophytol 2.4%.

The leaves gave ascorbic acid, an- thranilic acid and its glucoside, indole oxygenase, alkaloid jasminine and salicylic acid.

The flowers contain pyridine and nicotinate derivatives; tested positive for indole.

The flowers and leaf juice is used for treating tumours.

Dosage: Dried leaves—10-20 g powder for decoction (API, Vol. III.); Juice—10-20 ml. (CCRAS.).... jasminum officinale

Juncus Effusus

Linn.

Synonym: J. communis E. Mey.

Family: Juncaceae.

Habitat: Eastern Himalayas and Khasi Hills.

English: Rush, Matting Rush.

Action: Pith—antilithic, discutient, diuretic, depurative, pectoral. Root—diuretic, especially in strangury.

The leaves gave flavonoids, lutcoline- 7-glucoside, diosmin and hesperidin; aerial parts gave phenolic constituents, effusol and juncusol. Juncusol is antimicrobial. A dihydrodibenzoxepin, isolated from the plant, showed cyto- toxic activity.... juncus effusus

Juniperus Communis

Linn. var. saxatillis Palias.

Synonym: J. communis auct. non L.

Family: Pinaceae; Cupressaceae.

Habitat: Native to Europe and North America. Distributed in Western Himalayas from Kumaon westwards at 1,700-4,200 m.

English: Common Juniper.

Ayurvedic: Hapushaa, Havushaa, Haauber, Matsyagandha.

Unani: Abahal, Haauber, Hubb-ul- arar, Aarar.

Action: Berries—diuretic, urinary antiseptic, carminative, digestive, sudorific, anti-inflammatory, emmenagogue. Used for acute and chronic cystitis, renal suppression (scanty micturition), catarrh of the bladder, albuminuria, amenorrhoea, leucorrhoea. Aerial parts—abortifacient.

Key application: In dyspepsia. (German Commission E.) Juniper berry may increase glucose levels in diabetics. (ESCOP.) As a diuretic.

(The British Herbal Pharmacopoeia.)

The Ayurvedic Pharmacopoeia of India recommends the dried fruit in malabsorption syndrome.

Animal studies have shown an increase in urine excretion as well as a direct effect on sooth muscle contraction. (German Commission E, ESCOP.)Con- traindicated in kidney disease. (Sharon M. Herr.)

(In Kerala, Hapushaa and Mundi are considered to be synonyms; Syphaer- anthus indicus,Asteraceae, is used as Hapushaa.)

The major constituents of the volatile oil are alpha-pinene, sabinene and alpha-terpinene. Methanolic extract of the plant gave several labdane diter- penoids and diterpenes. The leaves contain the biflavones, cupressufla- vone, amentoflavone, hinokiflavone, isocryptomerin and sciadopitysin. The berries also contain condensed tannins. Seeds gave haemagglutinin.

Juniperus recurva Buch-Ham ex D. Don, syn. J. excelsa auct. non-Bieb. (temperate Himalaya from Kashmir to Bhutan) is known as Weeping Blue Juniper. J. macropoda Boiss. (the Himalaya from Nepal onwards) is known as Himalayan Indian Juniper. Both the species are used like J. communis var. saxatillis.

The berries gave a diterpene ketone, sugrol, beta-sitosterol glucoside and 10-nonacosanol.

Plant extract can be used in toothpastes and mouth-rinses to reduce dental plaque and bleeding.

Dosage: Dried fruit—2-6 g powder. (API, Vol. III.)... juniperus communis

Justica Tranquebariensis

Linn. f.

Family: Acanthaceae.

Habitat: Deccan, Mysore southwards.

Folk: Sivanarvembu (Tamil Nadu).

Action: Leaves—cooling, aperient; given for smallpox to children, bruised leaves applied to contusions.

The alcoholic extract of the aerial parts yielded several lignans, phy- tosterols, brassicasterol, campesterol, 7,22-ergostadienol, stigmasterol, sitosterol, spinasterol, 28-isofucostil and a sterol glucoside, beta-sitosterol-3-O- glucoside.

Justica vasculosa Wall. (Eastern Himalayas, Assam Khasi Hills) is also used for inflammations.... justica tranquebariensis

Kalanchoe Integra

(Medic.) Kuntze.

Synonym: K. brasiliensis Cambress. K. spathulata Roxb.

Family: Crassulaceae.

Habitat: Tropical Himalayas from Kashmir to Bhutan, on Lushai hills and in the Deccan.

Ayurvedic: Parnabija (var.).

Unani: Zakhm-e-Hayaat.

Folk: Rungru, Tatara. Bakalpattaa, Patkuari (Kumaon). Hathokane (Nepal).

Action: Plant—hypotensive, antiarrhythmic.

Aqueous extract of the leaves depressed CNS and potentiated barbiturate-induced hypnosis in mice.

The flowers yielded triterpenoids— friedelin, taraxerol and glutinol and a mixture of long chain hydrocarbons, n-alkanols and sterols. Kaempferol and its 3-O-rhamnoside, patuletin and patuletin-3, 7-di-O-rhamnoside, quer- cetin and quercetin-3-O-glucoside- 7-O-rhamnoside are reported from leaves and flowers.

The leaves exhibit wound healing properties.... kalanchoe integra

Kalanchoe Pinnata

(Lam.) Pers.

Synonym: Bryophyllum pinnatum (Lam.) Oken. B. calycinum Salisb.

Family: Crassulaceae.

Habitat: Throughout the warm and moist parts of India, especially abundant in West Bengal.

Ayurvedic: Parnabija, Pattharchuur, Pattharchat, Hemsaagar. (Paashaa- nabheda is a misleading synonym.)

Unani: Zakhm-e-Hayaat.

Siddha/Tamil: Runakalli.

Action: Leaf—anti-inflammatory, antifungal, antibacterial. Applied to wounds, burns, boils, swellings.

The methanolic extract of leaves exhibited potent anti-inflammatory activity against both exudative and proliferative phases of inflammation. The leaf extract also showed analgesic activity.

The leaves gave flavonoids—querce- tin, kaempferol, quercetin-3-diarabi- noside andkaempferol-3-glucoside; also n-hentriacontane, n-tritriacontane, alpha- and beta-amyrin and sitosterol; p-coumaric, ferulic, syringic, caffeic and p-hydroxybenzoic acids.... kalanchoe pinnata

Lavandula Stoechas

Linn.

Family: Papilionaceae; Fabaceae.

Habitat: Mediterranean region and Asia Minor. Dried plant and flowers are imported into Mumbai from Persian Gulf.

English: Arabian or French Lavender.

Unani: Ustukhuddus, Alfaajan.

Folk: Dhaaru.

Action: Flowers—antidepressive, sedative, anticonvulsant, carminative, antispasmodic, antibacterial, antiseptic. Used in depression, nervous headache, sluggish circulation, physical and mental exhaustion, insomnia, epilepsy, neuralgia and rheumatic affections.

Oil—rubefacient, antimicrobial. Used for nervous palpitations, giddiness, spasm and colic. Relieves sprains, neuralgia and rheumatism; rubbed for stimulating paralysed limbs. Applied to sores, burns, scalds and varicose veins.

Plant—used for the treatment of epilepsy and chronic sinusitis in Unani medicine.

Aerial parts of the plant contain oleanolic, ursolic and vergatic acid, beta-sitosterol, alpha-amyrin and its acetate, lupeol, erythrodiol, luteolin, acacetin and vitexin.

The leaves contain polyphenols, api- genin-7-O-beta-D-glucoside, luteolin andits7-O-beta-D-glucoside, and7-O- beta-D-glucuronide, rosmarinic acid, and 6-O-caffeoyl glucose.

For depression, tincture of lavender flower (1: 5 in 50% alcohol), 60 drops per day, has been used for 4 weeks in Western herbal. (Natural Medicines Comprehensive Database, 2007.)... lavandula stoechas



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