(GAD) a common enzyme that, because of similarities to certain bacterial proteins, can provoke an autoimmune reaction against the beta cells of the pancreas (see islet cell antibodies) progressing to type 1 *diabetes mellitus.... glutamic acid decarboxylase
n. an enzyme that catalyses the transfer of an amino group from an amino acid to an ?-keto acid in the process of *transamination. Examples include *aspartate aminotransferase (AST), which catalyses the transamination of glutamate and oxaloacetate to ?-ketoglutarate and aspartate, and *alanine aminotransferase (ALT), converting glutamate and pyruvate to ?-ketoglutarate and alanine.... transaminase