Granulations Health Dictionary

Granulations: From 1 Different Sources


Small masses of formative cells containing loops of newly formed blood vessels which spring up over any raw surface, as the ?rst step in the process of healing of wounds. (See ULCER; WOUNDS.)
Health Source: Medical Dictionary
Author: Health Dictionary

Ulcer

Destruction of the skin’s surface tissues resulting in an open sore. A similar breach may occur in the surface of the mucous membrane lining body cavities – for example, the stomach, duodenum or colon (see COLITIS). Usually accompanied by pain and local in?ammation, ulcers can be shallow or deep, with a crater-like shape. An ulcer may heal naturally, but on certain parts of the body – legs (venous ulcers, see below) or bony protuberances (decubitus ulcers, see below) – they can become chronic and di?cult to treat. When an ulcer heals, granulations (well-vascularised connective tissue) form which become ?brous and draw the edges of the ulcer together. Any damage to the body surface may develop into an ulcer if the causative agent is allowed to persist – for example, contact with a noxious substance or constant pressure on an area of tissue with poor circulation. Treatment of skin ulcers is e?ected by cleaning the area, regular dry dressings and local or systemic ANTIBIOTICS depending upon the severity of the ulcer.

Decubitus ulcer Also known as pressure or bed sore. Occurs when there is constant pressure on and inadequate oxygenation of an area of skin, usually overlying a bony protuberance. Elderly or in?rm people, or individuals with debilitating, emaciating or neurological illnesses, are vulnerable to the condition. Long-term pressure from a bed, wheelchair, cast or splint is the usual cause. Loss of skin sensation is a contributory factor, and muscle and bone as well as skin may be affected.

Treatment The most important treatment is prevention, keeping the patient’s back, buttocks, heels and other pressure-points clean and dry, and regularly changing his or her position. If ulcers do develop, repeated local DEBRIDEMENT, protective dressings and (in serious cases) surgical treatment are required, accompanied by an appropriate antibiotic if infection is persistent.

Venous ulcer This occurs on the lower leg or ankle and is caused by chronic HYPERTENSION in the deep leg VEINS, usually the consequences of previous deep vein thrombosis (DVT) – see THROMBOSIS; VEINS, DISEASES OF – which has destroyed the valvular system in the vein(s). The ulcer is usually preceded by chronic OEDEMA, often local eczema (see DERMATITIS), and bleeding into the skin that produces brown staining. Varicose veins may or may not be present. Control of the oedema by compression and encouragement to walk is central to management.... ulcer

Cancer – Tongue

May be scirrhus or epithelial.

Causes. Smoking, alcohol, jagged teeth, chemical irritants, septic toxins, sprayed fruit and vegetables, poisoning by lead, arsenic and other chemicals, additives, hot foods, spicy curries and peppers, chewing tobacco.

Over 80 per cent found to be present in old syphilitic cases. Charles Ryall, surgeon, Cancer Hospital, regarded the two as comparable with that between syphilis and tabes. Dr F. Foester, Surgeon, concluded that epithelioma of the tongue as far more frequently preceded by syphilis than any other form of cancer.

(Hastings Gilford FRCS, “Tumours and Cancers”)

The condition may arise from a gumma or patch of leucoplakia (white patches) – at one time known as smoker’s tongue.

Of possible value. Alternatives:– Many plants have been shown to produce neoplastic activity, as observed in discovery of anti-cancer alkaloids of the Vinca plant (Vinchristine) and Mistletoe. Dr Wm Boericke confirms clinical efficacy of Clivers, promoting healthy granulations in ulcers and tumour of the tongue. Dr W.H. Cook advises a mouthwash of Goldenseal. For scirrhous hardening, juice of fresh Houseleek has a traditional reputation.

Tinctures. Equal parts Condurango and Goldenseal. 30-60 drops before meals in water; drops increased according to tolerance.

Local paint. Thuja lotion.

Case record. Dr Brandini, Florence, had a patient, 71, with inoperable cancer of the tongue. In the midst of his pain he asked for a lemon which immediately assuaged the pain. The next day gave him even greater relief. The doctor tried it on a number of similar patients with the same results, soaking lint in lemon juice.

Diet. See: DIET – CANCER.

Treatment by a general medical practitioner or hospital oncologist. ... cancer – tongue

Grapes

Vitis vinifera L.

Dr Joanna Brandt knew that grapes may sometimes check malignancy. Facing up squarely to the reality of cancer, she resolved not to take any medicines to check its course or alleviate the pain . . . neither would she submit to the surgeon’s knife.

For nine years she had been desperately seeking something to destroy the growth effectively, to eliminate virulent cancer toxins and rebuild new tissue.

At the conclusion of a seven-day fast she developed a craving for grapes. From the first mouthful she felt their purifying influence and a lift physically and mentally. She was miraculously cured.

As in other cases, improvement was attended by the senses becoming abnormally acute, dim eyes became bright, faded hair took on a new gloss, a lifeless voice became vibrant, the complexion cleared; teeth, loose and suppurating in their sockets became fixed and healthy.

In “The Grape Cure”, she records: “While the system is drained of its poisons, external wounds are kept open with frequent applications of Grape poultices and compresses . . . No scabs or crusts are formed as long as the lesions are kept moist . . . From glistening bones outwards, the process of reconstruction goes on. Healthy, rosy granulations of new flesh appear and cavities are filled in.”

The body is prepared for the regime by fasting for 2-3 days, drinking plenty of pure cold water and by taking a two-pint enema of lukewarm water daily.

After the fast, she advises – “Drink one or two glasses of cold water on rising. Half hour later, have a meal of grapes, discard seeds, chew skins thoroughly, swallowing a few for medicine and fibre. Have a grape meal every two hours from 8am to 8pm (7 meals daily). Continue two weeks – even for one month. Begin with 1, 2 or 3 ounces per meal, increasing gradually to half pound. The maximum should not exceed 4 pounds. Patients taking large quantities should allow 3 hours for digestion and not take all skins.”

After years of suffering, Dr Brandt discovered a cure which worked in her particular case and which she was able to repeat in a number of others. ... grapes

Arachnoid Villus

one of the thin-walled projections outwards of the arachnoid membrane into the blood-filled sinuses of the dura, acting as a one-way valve for the flow of cerebrospinal fluid from the subarachnoid space into the bloodstream. Large villi, known as arachnoid granulations (or Pacchionian bodies), are found in the region of the superior sagittal sinus. They may be so distended as to cause pitting of the adjacent bone.... arachnoid villus

Intention

n. 1. a process of healing. Healing by first intention is the natural healing of a wound or surgical incision when the edges are brought together under aseptic conditions and *granulation tissue forms. In healing by second intention the wound edges are separated and the cavity is filled with granulation tissue over which epithelial tissue grows from the wound edges. In healing by third intention the wound ulcerates, granulations are slow to form, and a scar forms at the wound site. 2. evaluation of a person’s aims or purpose in undergoing an action, which is important for the assessment and attribution of responsibility in ethicolegal questions and defined legally for the purposes of criminal law. See also doctrine of double effect.... intention



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