Granuloma Health Dictionary

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Granuloma: From 4 Different Sources

An aggregation of cells of a type associated with chronic inflammation. They usually occur as a reaction to certain infections, such as tuberculosis, or a foreign body, such as a suture, but they may develop for unknown reasons in conditions such as sarcoidosis.

A pyogenic granuloma is an excess of granulation tissue developing at the site of an injury to the skin or mucous membrane. (See also granuloma annulare; granuloma inguinale.)

Health Source: BMA Medical Dictionary
Author: The British Medical Association
A non-malignant or new growth made up of granulation tissue. This is caused by various forms of chronic in?ammation, such as SYPHILIS and TUBERCULOSIS.
Health Source: Medical Dictionary
Author: Health Dictionary
n. (pl. granulomata or granulomas) a localized collection of cells, usually produced in response to an infectious process, that is characterized by the presence of aggregates of epithelioid *histiocytes; giant cells, monocytes, or lymphocytes may also be present. The types of cells comprising a granuloma (of which there may be many or few) and their arrangement can assist in diagnosing the cause of the response; this is important in the diagnosis of tuberculosis, sarcoidosis, Crohn’s disease, and the presence of certain foreign bodies (e.g. starch, talc). Other conditions giving rise to granulomata include syphilis, leprosy, and coccidioidomycosis, and a granuloma may also occur around the apex of a tooth root as a result of inflammation or infection of its pulp. —granulomatous adj.
Health Source: Oxford | Concise Colour Medical Dictionary
Author: Jonathan Law, Elizabeth Martin

Granuloma Inguinale

Donovanosis.... granuloma inguinale

Granuloma Annulare

A harmless skin condition characterized by a circular, raised area of skin, which spreads outwards to form a ring.

The disorder occurs most commonly in children, usually on the hands.

The cause is unknown.

No treatment is necessary.

In most cases, the affected skin heals completely over a period of several months or years.... granuloma annulare

Pyogenic Granuloma

A common, noncancerous skin tumour that develops on exposed areas after minor injury. It can be removed surgically, by electrocautery, or by cryosurgery.... pyogenic granuloma

Wegener’s Granulomatosis

A rare disorder in which granulomas (nodular collections of abnormal cells), associated with areas of chronic tissue inflammation due to vasculitis, develop in the nasal passages, lungs, and kidneys. It is thought that the condition is an autoimmune disorder (in which the body’s natural defences attack its own tissues). Principal symptoms include a bloody nasal discharge, coughing (which sometimes produces bloodstained sputum), breathing difficulty, chest pain, and blood in the urine. There may also be loss of appetite, weight loss, weakness, fatigue, and joint pains.

Treatment is with immunosuppressant drugs, such as cyclophosphamide or azathioprine, combined with corticosteroids to alleviate symptoms and attempt to bring about a remission.

With prompt treatment, most people recover completely within about a year, although kidney failure occasionally develops.

Without treatment, complications may occur, including perforation of the nasal septum, causing deformity of the nose; inflammation of the eyes; a rash, nodules, or ulcers on the skin; and damage to the heart muscle, which may be fatal.... wegener’s granulomatosis

Eosinophilic Granulomatosis With Polyangiitis

see Churg–Strauss syndrome.

EPA (eicosapentaenoic acid) see omega-3 fatty acids.... eosinophilic granulomatosis with polyangiitis

Granuloma Gravidarum

see pregnancy epulis.... granuloma gravidarum

Granulomatosis

n. any condition marked by multiple widespread *granulomata. See also granulomatosis with polyangiitis.... granulomatosis

Granulomatosis With Polyangiitis

(GPA) an autoimmune disease, formerly known as Wegener’s granulomatosis, predominantly affecting the sinuses, lungs, and kidneys, and characterized by blood-vessel inflammation and the formation of necrotizing *granulomas. It is associated with the presence of antineutrophil cytoplasmic antibodies (*ANCA). Untreated the disease is usually fatal, but it can be controlled with corticosteroids, cyclophosphamide, or rituximab.... granulomatosis with polyangiitis

Umbilical Granuloma

an overgrowth of tissue during the healing process of the umbilicus (belly button). It is a moist fleshy red lump of tissue seen in some babies in the first few weeks of life after the umbilical cord remnant has dried and fallen off. It can sometimes be seen in adults after navel piercings. If left untreated, the granuloma can take months to resolve.... umbilical granuloma

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