the matrix of *connective tissue, in which various cells and fibres are embedded.
An active ingredient that is intended to furnish pharmacological activity or other direct effect in diagnosis, cure, mitigation, treatment or prevention of diseases or to effect the structure or any function of the human body... drug substance
The use of drugs or other substances for a purpose other than that which is normally recommended. Stimulant drugs, solvents, and glue, are all commonly abused. Problems may arise due to adverse effects or from the habit-forming potential of the substance. (See also drug abuse.)... substance abuse
the nonclinical, or recreational, use of pharmacologically active substances such that continued use results in adverse physiological or psychological effects (see dependence). Substances commonly misused include alcohol (see alcoholism), *amphetamines, *cannabis, *cocaine, *Ecstasy, *heroin, *lysergic acid diethylamide (LSD) and organic solvents (by inhalation), but also many prescribed medications, such as co-codamol, quetiapine, or pregabalin.... substance misuse