A bacterium now known to be the cause of most peptic ulcers as well as a factor in stomach cancer. The bacterium is thought to damage the mucus layer of the stomach and duodenum, allowing gastric acid to cause ulceration. Treatment with antibiotics to eradicate the infection has proved successful in achieving long-term recovery from peptic ulcers.
A bacterium which colonises the stomach. While it may cause no disease, it has a tendency to produce in?ammation – gastritis. This may progress in some people to peptic ulceration (see PEPTIC ULCER), and even to gastric cancer. The bacterium can be identi?ed on blood testing or, more accurately, by obtaining a biopsy of the stomach wall by ENDOSCOPY. It can be eradicated by treatment with PROTON-PUMP INHIBITORS and antibiotics.