Helminthiasis Health Dictionary

Willd. var. indica Benth.

Synonym: A. nilotica (Linn.) Delile subsp. indica (Benth.) Brenan.

Family: Mimosaceae.

Habitat: Throughout the drier parts of India.

English: Babul, Black Babul, Indian Gum arabic tree.

Ayurvedic: Babbuula, Babbuuri, Baavari, Aabhaa, Shuulikaa, Shitaka, Kinkiraata, Yugmakantaka, Sukshmapatra, Pitapushpaka.

Unani: Aqaaqia, Babuul, Kikar, Mughilaan, Samur.

Siddha/Tamil: Karu-velamaram, Karuvelei. Velampisin (gum).

Action: Stembark—astringent, spasmolytic, hypoglycaemic. Gum—demulcent (soothing agent for inflammatory conditions of the respiratory, digestive and urinary tracts). Pods—used in urogenital disorders. Seeds—hypoglycaemic in normal rats; no such effect in diabetic rats. Seed oil—antifungal. Flowers, pods and gum resin—used in diarrhoea and dysentery.

Along with other therapeutic applications, The Ayurvedic Pharmacopoeia of India indicates the use of stembark in acute diarrhoea and helminthiasis.

Tannin contents of the bark varies considerably (12-20%). Several poly- phenolic compounds have been reported in the bark, also in the pods. The whole pod contains 12-19% tannins and 18-27% after the removal of seeds.

The seeds of A. benthamii, A. nilotica ssp. subulata, probably same as ssp. indica, are considered hypoglycaemic. Some seed components stimulate insulin secretion by beta cells.

The gum contains galactose; l-ara- binose, l-rhamnose and aldobiouronic acids, also arabinobioses.

The flowers contain flavonoids— kaempferol-3-glucoside, iso-quercitrin and leucocyanidin.

Dosage: Stembark—20-30 g for decoction. (API Vol. I.)... acacia arabica

Acacia catechu

Mimosaceae

San:Khadirah;

Hin:Khair, Khaira;

Ben: Kuth;

Mal: Karingali;

Tam: Karunkali;

Tel: Sandra, Khandiramu;

Kan: Kaggali

Importance: Catechu is a medium deciduous tree commonly used as a blood purifier and for leoprosy and leucoderma. Catechu or Cutch tree bark is useful in melancholia, conjunctivitis and haemoptysis. It is useful in vitiated conditions of kapha and pitta, catarrh, cough, pruritus, leprosy, leucoderma, skin diseases, helminthiasis, anorexia, diarrhoea, dysentery, foul ulcers and wounds, haemoptysis, haematemesis, haemorrhages, intermittent fever, inflammations, odontopathy, anaemia, diabetes, splenomegaly and pharyngodyna. The gummy extract of the wood (kath) is useful in laryngopathy, flatulence, anorexia, ulcers, wounds, helminthiasis, leucoderma, leoprosy, skin diseases, urorrhea, colporrhagia, erysipelas and odontopathy. For leprosy, root, leaf, flower, bark and fruits are made into a decoction which is given orally as well as for external dressing. In Unani system it is used in “Marham Kharish Jadid” for skin diseases. “Khadirarisht” is an oral medicine, while “Marham” is for external application.

Distribution:It is widely distributed in tropical countries. In India, it is observed from the Indus eastwards to Assam and throughout Peninsular India.

Botany: The genus Acacia belonging to the family Mimosaceae consists of a number of species. The important ones are listed as below:

A. catechu Willd. A. caesia Willd. A. arabica Willd. A. concinna DC.

A. farnesiana Willd.

A. ferruginea DC.

A. instia W. & A. syn. A. caesia Willd.

A. jacquemontii Benth. A. leucophloea Willd. A. modesta Wall.

A. pinnata (Linn.) Willd.

A. pycnantha Benth.

A. senegal Willd.

A. suma Buch-Ham. syn. A. suma Kurz.

A. catechu is a moderate sized deciduous tree, 9-12m in height with dark greyish or brown rough bark and hooked short spines. Leaves are bipinnately compound, leaflets 30-50 pairs, main rachis pubescent with a large conspicuous gland near the middle of the rachis. Flowers are pale yellow, sessile in peduncled axiallary spikes. Fruits are flat brown pods, shiny and with a triangular beak at the apex and narrowed at the base. Seeds are 3-10 per pod.

The gummy extract of the wood is commercially known as ‘ Kath’ or ‘Cutch’. The cutch available in the market is brittle, of different shapes and dark brown in colour. On breaking, it is found to be shiny and form crystal like pieces (Warrier et al, 1993).

Agrotechnology: Catechu is suited to hilly areas and rocky places. The plant is propagated by seeds.

Seeds are soaked in water for 6 hours and sown in seedbeds. Seeds germinate within a month. At four-leaf stage, seedlings are planted in polybags. Two months old seedlings from the polybags are used for transplanting. Pits of size 50cm cube are taken at a distance of 4-5m between plants and filled with topsoil, sand and dried cowdung in 1:1:1 ratio. Seedlings are planted in these pits. Application of organic manure every year during the rainy season is beneficial. Regular weeding is to be carried out. Pruning of branches and tender shoots developing from the base of the plant can be done from second year onwards. Tree is to be grown as single stemmed one. Flowering and fruiting commences from fourth year onwards. At the end of tenth year, the tree can be cut and heartwood collected (Prasad et al, 1997).

Properties and Activity: Heartwood contains kaempferol, dihydro kaempferol, taxifolin, iso rhamnetin(+)- afzelchin, a dimeric procyanidin, quercetin, (-)epi-catechin, (-)catechin, fisetin, quercetagetin and (+)-cyanidanol. The main constituent of heartwood is catechin and catechu tannic acid. Catechin is a mixture of at least four isomers and L(-)epicatechin has been isolated and characterised (Rao et al,1948; Husain et al,1992).

The bark is anthelmintic, antipyretic, antiinflammatory and antileprotic. The flowers are antigonorrhoeic. The cutch from wood is anthelmintic, tonic and aphrodisiac. Bark and cutch are antidiarrhoeal, astringent and stomachic. Cyanidanol is hepatoprotective. The wood is hypoglycaemic, antiinflammatory and hypotensive. The stem is spasmolytic and antiviral (Husain et al, 1992).... catechu

Cucurbitaceae

The family Cucurbitaceae includes a large group of plants which are medicinally valuable. The important genera belonging to the family are Trichosanthes, Lagenaria, Luffa, Benincasa, Momordica, Cucumis, Citrullus, Cucurbita, Bryonopsis and Corallocarpus. The medicinally valuable species of these genera are discussed below.

1. Trichosanthes dioica Roxb.

Eng: Wild Snake-gourd; San: Meki,Pargavi, Parvara, Patola;

Hin: Palval, Parvar

Ben: Potol;

Mal: Kattupatavalam, Patolam;

Tam: Kombuppudalai;

Tel: Kommupotta

Wild snake-gourd is a slender-stemmed, extensively climbing, more or less scabrous and woolly herb found throughout the plains of N. India, extending to Assam and W. Bengal. Tendrils are 2-4 fid. Leaves are 7.5x5cm in size, ovate-oblong, cordate, acute, sinuate- dentate, not lobed, rigid, rough on both surface and with a petiole of 2cm. Flowers are unisexual. Male flowers are not racemed but woolly outside. Calyx tube is 4.5cm long, narrow, teeth linear and erect. Anthers are free. Fruit is 5.9cm long, oblong or nearly spherical, acute, smooth and orange-red when ripe. Seeds are half-ellipsoid, compressed and corrugated on the margin (Kirtikar and Basu, 1988). The unripe fruit of this is generally used as a culinary vegetable and is considered very wholesome and specially suited for the convalescent. The tender shoots are given in decoction with sugar to assist digestion. The seeds are useful for disorders of the stomach. The leaf juice is rubbed over the chest in liver congestion and over the whole body in intermittent fevers (Nadkarni, 1998). The fruit is used as a remedy for spermatorrhoea. The fresh juice of the unripe fruit is often used as a cooling and laxative adjunct to some alterative medicines. In bilious fever, a decoction of patola leaves and coriander in equal parts is given. The fruit in combination with other drugs is prescribed in snakebite and scorpion sting (Kirtikar and Basu, 1988).

Fruits contain free amino acids and 5-hydroxy tryptamine. Fatty acids from seeds comprise elaeostearic, linoelic, oleic and saturated acids. The aerial part is hypoglycaemic. Leaf and root is febrifuge. Root is hydragogue, cathartic and tonic. Unripe leaf and fruit is laxative (Husain et al, 1992). The plant is alterative and tonic. Leaves are anthelmintic. Flower is tonic and aphrodisiac. The ripe fruit is sour to sweet, tonic, aphrodisiac, expectorant and removes blood impurities.

The other important species belonging to the genus Trichosanthes are as follows.

T. palmata Roxb. T. cordata Roxb. T. nervifolia Linn.

T. cucumerina Linn.

T. anguina Linn.

T. wallichiana Wight. syn. T. multiloba Clarke

2. Lagenaria vulgaris Ser. syn. Cucurbita Lagenaria Linn. ; Roxb.

Eng: Bottle gourd San: Alabu Hin: Lauki, Jangli-khaddu

Ben: Lau, Kodu

Mal: Katuchuram, Churakka

Tam: Soriai-kay

Tel: Surakkaya

Bottle gourd is a large softly pubescent climbing or trailing herb which is said to be indigenous in India, the Molucas and in Abyssinia. It has stout 5-angled stems with bifid tendrils. Leaves are ovate or orbiculate, cordate, dentate, 5-angular or 5-lobed, hairy on both surfaces. Flowers are large, white, solitary, unisexual or bisexual, the males long and females short peduncled. Ovary is oblong, softly pubescent with short style and many ovules. Fruits are large, usually bottle or dumb-bell-shaped, indehiscent and polymorphous. Seeds are many, white, horizontal, compressed, with a marginal groove and smooth. There are sweet fruited and bitter-fruited varieties (Kirtikar and Basu, 1988). The fruit contains a thick white pulp which, in the cultivated variety (kodu) is sweet and edible, while in the smaller wild variety (tamri) it is bitter and a powerful purgative. The seeds yield clear limpid oil which is cooling and is applied to relieve headache. The pulp of the cultivated forms is employed as and adjunct to purgatives and considered cool, diuretic and antibilious, useful in cough, and as an antidote to certain poisons. Externally it is applied as a poultice. The leaves are purgative and recommended to be taken in the form of decoction for jaundice (Nadkarni, 1998). In the case of sweet-fruited variety, the stem is laxative and sweet. The fruit is sweet oleagenous, cardiotonic, general tonic, aphrodisiac, laxative and cooling. In the case of bitter-fruited variety, the leaves are diuretic, antibilious; useful in leucorrhoea, vaginal and uterine complaints and earache. The fruit is bitter, hot, pungent, emetic, cooling, cardiotonic, antibilious; cures asthma, vata, bronchitis, inflammations ulcers and pains.

3. Luffa acutangula (Linn.) Roxb.

Eng: Ridged gourd; San: Dharmargavah, Svadukosataki;

Hin: Tori, Katitori;

Ben: Ghosha

Mal: Peechil, Peechinga;

Tam: Pikangai, Prikkangai;

Tel: Birakaya;

Kan: Kadupadagila

Ridged gourd or ribbed gourd is a large monoecious climber cultivated throughout India. It is with 5-angled glabrous stems and trifid tendrils. Leaves are orbicular-cordate, palmately 5-7 lobed, scabrous on both sides with prominent veins and veinlets. Flowers are yellow, males arranged in 12-20 flowered axillary racemes. Female flowers are solitary, arranged in the axils of the males. Ovary is strongly ribbed. Fruits are oblong-clavate with 10-sharp angles 15-30cm long, tapering towards the base. Seeds are black, ovoid-oblong, much compressed and not winged (Warrier et al, 1995). The leaves are used in haemorrhoids, leprosy, granular-conjunctivitis and ringworm. The seeds are useful in dermatopathy. The juice of the fresh leaves is dropped into the eyes of children in granular conjunctivitis, also to prevent the lids from adhering at night on account of excessive meihomian secretion (Nadkarni, 1998). Fruits are demulcent, diuretic, tonic, expectorant, laxative and nutritive. The seeds are bitter, emetic, cathartic, expectorant and purgative.

The other important species of the genus Luffa are:

L. aegyptiaca Mill.

L. acutangula var. amara Clarke

L. echinata Roxb.

4. Benincasa hispida (Thumb.) Cogn. syn. B. cerifera Savi.

Eng: Ash gourd, White gourd melon; San: Kusmandah;

Hin: Petha, Raksa;

Ben: Kumra

Mal: Kumpalam;

Tam: Pusanikkai;

Kan: Bile Kumbala;

Tel: Bodigummadi

Ash gourd or White gourd melon is a large trailing gourd climbing by means of tendrils which is widely cultivated in tropical Asia. Leaves are large and hispid beneath. Flowers are yellow, unisexual with male peduncle 7.5-10cm long and female peduncle shorter. Fruits are broadly cylindric, 30-45cm long, hairy throughout and ultimately covered with a waxy bloom. The fruits are useful in asthma, cough, diabetes, haemoptysis, hemorrhages from internal organs, epilepsy, fever and vitiated conditions of pitta. The seeds are useful in dry cough, fever, urethrorrhea, syphilis, hyperdipsia and vitiated conditions of pitta (Warrier et al,1993). It is a rejuvenative drug capable of improving intellect and physical strength. In Ayurveda, the fresh juice of the fruit is administered as a specific in haemoptysis and other haemorrhages from internal organs. The fruit is useful in insanity, epilepsy and other nervous diseases, burning sensation, diabetes, piles and dyspepsia. It is a good antidote for many kinds of vegetable, mercurial and alcoholic poisoning. It is also administered in cough, asthma or respiratory diseases, heart diseases and catarrah. Seeds are useful in expelling tapeworms and curing difficult urination and bladder stones. The important formulations using the drug are Kusmandarasayana, Himasagarataila, Dhatryadighrita, Vastyamantakaghrita, Mahaukusmandakaghrita, etc. (Sivarajan et al, 1994).

Fruits contain lupeol, -sitosterol, n-triacontanol, vitamin B, mannitol and amino acids. The fruit is alterative, laxative, diuretic, tonic, aphrodisiac and antiperiodic. Seed and oil from seed is anthelmintic (Husain et al, 1992).

5. Momordica charantia Linn.

Eng: Bitter gourd, Carilla fruit San: Karavellam

Hin: Karela, Kareli

Mal: Kaypa, Paval

Tam: Pavakkai, Paval, Pakar

Tel: Kakara

Bitter gourd or Carilla fruit is a branched climbing annual which is cultivated throughout India. It is a monoecious plant with angled and grooved stems and hairy or villous young parts. Tendrils are simple, slender and elongate. Leaves are simple, orbicular, cordate and deeply divided into 5-7 lobes. Flowers are unisexual, yellow and arranged on 5-10cm long peduncles. Fruits are 5-15cm long with 3-valved capsules, pendulous, fusiform, ribbed and beaked bearing numerous triangular tubercles. Seeds are many or few with shining sculptured surface. The roots are useful in coloptosis and ophthalmopathy. The leaves are useful in vitiated conditions of pita, helminthiasis, constipation, intermittent fever, burning sensation of the sole and nyctalopia. The fruits are useful in skin diseases, leprosy, ulcers, wounds, burning sensation, constipation, anorexia, flatulence, colic, helminthiasis, rheumatalgia, gout, diabetes, asthma, cough, dysmenorrhoea, impurity of breast milk, fever and debility. Seeds are useful in the treatment of ulcers, pharyngodynia, and obstructions of the liver and spleen. The leaves and fruits are used for external application in lumbago, ulceration and bone fractures and internally in leprosy, haemorrhoids and jaundice (Warrier et al, 1995). The drug improves digestion, calms down sexual urge, quells diseases due to pitta and kapha and cures anaemia, anorexia, leprosy, ulcers, jaundice, flatulence and piles. Fruit is useful in gout, rheumatism and complaints of liver and spleen (Nadkarni, 1954; Aiyer and Kolammal, 1966; Mooss, 1976; Kurup et al, 1979). Kaccoradi taila is an important preparation using the drug (Sivarajan et al, 1994).

The seeds give triterpene glycosides, named momordicosides A, B, C, D and E, which are glycosides of cucurbit-5-en-triol, tetraol or pentaol. Leaves and vines give tetracyclic triterpenes-momordicines I, II and III (bitter principles). Immature fruits give several non-bitter and 2 bitter cucurbitacin glycosides. Four of the non-bitter glycosides, momordicosides F1, F2, G and I and the bitter momordicosides; K and L have also been characterized. Fruits, seeds and tissue culture give a polypeptide which contained 17 types of amino acids and showed hypoglycaemic activity. Fruits also give 5-hydroxy tryptamine and a neutral compound charantin (a steroidal glucoside), diosgenin, cholesterol, lanosterol and -sitosterol. Leaf is emetic, purgative and antibilious. Fruit is stomachic, tonic, carminative, febrifuge, antirheumatic and hypoglycaemic. Root is astringent. Fruit and leaf is anti-leprotic. Fruit, leaf and root are abortifacient and anti-diabetic. Leaf and seed is anthelmintic. Seed oil possesses antifeeding and insecticidal properties. Unsaponifiable matter from seed oil exhibited pronounced inhibitory activity against gram negative bacteria. Seed and fruit are hypoglycaemic, cytotoxic and anti-feedant (Husain et al, 1992).

Other important species belonging to the genus Momordica are as follows.

M. dioica Roxb.

M. cochinchinensis Spreng.

M. tuberosa Cogn.

M. balsamina Linn.

6. Cucumis melo Linn. syn. C. melo Linn. var. cultis Kurz., C. pubescens

Willd., C. callosus (Rottl.) Cogn.

Eng: Sweet melon San,

Hin: Kharbuja

Ben: Kharmul

Mal: Mulam

Tam: Chukkari-kai, Thumatti-kai, Mulampazham

Tel: Kharbuja-doshavSweet melon is a creeping annual extensively cultivated throughout India, found wild in India, Baluchistan and tropical Africa. The stem is creeping, angular and scabrous. Leaves are orbicular-reniform in outline, 5-angled or lobed, scabrous on both surfaces and often with soft hairs. Lobes of leaves are not very deep nor acute and with 5cm long petiole. Female peduncle is 5cm. Fruit is spherical, ovoid, elongate or contorted, glabrous or somewhat hairy, not spinous nor tuberculate.

Cucumis melo includes two varieties, namely,

C. melo var. momordica syn. C. momordica Roxb.

C. melo var. utilissimus Duthie & Fuller. syn. C. utilissimus Roxb.

The fruit is eaten raw and cooked. Its pulp forms a nutritive, demulcent, diuretic and cooling drink. It is beneficial as a lotion in chronic and acute eczema as well as tan and freckles and internally in cases of dyspepsia. Pulp mixed with cumin seeds and sugar candy is a cool diet in hot season. Seeds yield sweet edible oil which is nutritive and diuretic, useful in painful discharge and suppression of urine. The whole fruit is useful in chronic eczema (Kirtikar & Basu, 1988).

Seeds contain fatty acids-myristic, palmitic, oleic, linoleic; asparagine, glutamine, citrulline, lysine, histidine, arginine, phenylalanine, valine, tyrosine, leucine, iso-leucine, methionine, proline, threonine, tryptophan and crystine. Seed is tonic, lachrymatory, diuretic and urease inhibitor. Fruit pulp is eczemic. Fruit is tonic, laxative, galactagogue, diuretic and diaphoretic. The rind is vulnerary (Husain et al, 1992).

7. Cucumic sativus Linn.

Eng: Cucumber, Common cucumber; San: Trapusah;

Hin,

Ben: Khira;

Mal: Vellari

Tam: Vellarikkai, Pippinkai;

Kan: Mullusavte;

Tel: Dosekaya

Cucumber is a climbing annual which is cultivated throughout India, found wild in the Himalayas from Kumaon to Sikkim. It is a hispidly hairy trailing or climbing annual. Leaves are simple, alternate, deeply cordate, 3-5 lobed with both surfaces hairy and denticulate margins. Flowers are yellow, males clustered, bearing cohering anthers, connective crusted or elevated above the cells. Females are solitary and thickly covered with very bulbous based hairs. Fruits are cylindrical pepo of varying sizes and forms. Seeds are cream or white with hard and smooth testa. The fruits are useful in vitiated conditions of pitta, hyperdipsia, burning sensation, thermoplegia, fever, insomnia, cephalgia, bronchitis, jaundice, haemorrhages, strangury and general debility. The seeds are useful in burning sensation, pitta, constipation, intermittent fevers, strangury, renal calculus, urodynia and general debility (Warrier et al, 1994). The leaves boiled and mixed with cumin seeds, roasted, powdered and administered in throat affections. Powdered and mixed with sugar, they are powerful diuretic (Nadkarni, 1998). The fruits and seeds are sweet, refrigerant, haemostatic, diuretic and tonic. Other important species belonging to the genus are:

C. trigonus Roxb. syn. C. pseudo-colocynthis

C. prophetarum Linn.

8. Citrullus colocynthis (Linn.) Schrader. syn. Cucumis colocynthis Linn.

Eng: Colocynth, Bitter apple; San: Visala, Mahendravaruni;

Hin: Badi indrayan, Makkal

Ben: Makhal;

Mal: Kattuvellari (Valutu), Valiya pekkummatti;

Tel: Etti-puchcha

Tam: Paitummatti, Petummatti;

Colocynth or Bitter apple is found, cultivated and wild, throughout India in warmer areas. It is an extensively trailing annual herb with bifid tendrils angular branching stems and wooly tender shoots. Leaves are deeply divided, lobes narrow thick, glabrous or somewhat hairy. Flowers are unisexual, yellow, both males and females solitary and with pale-yellow corolla. Fruit is a globose or oblong fleshy indehiscent berry, 5-7.5cm in diameter and variegated with green and white. Seeds are pale brown. The fruits are useful in tumours, ascites, leucoderma, ulcers, asthma, bronchitis, urethrorrhea, jaundice, dyspepsia, constipations, elephantiasis, tubercular glands of the neck and splenomegaly (Warrier et al, 1994). It is useful in abnormal presentations of the foetus and in atrophy of the foetus. In addition to the above properties, the root has a beneficial action in inflammation of the breasts, pain in the joints; externally it is used in ophthalmia and in uterine pains. The fruit and root, with or without is rubbed into a paste with water and applied to boils and pimples. In rheumatism, equal parts of the root and long pepper are given in pill. A paste of the root is applied to the enlarged abdomen of children (Kirtikar and Basu, 1988). The fruit is useful in ascites, biliousness, jaundice, cerebral congestion, colic, constipation dropsy, fever, worms and sciatica. Root is given in cases of abdominal enlargement, cough, asthma, inflammation of the breast, ulcers, urinary diseases and rheumatism. Oil from seeds is used for poisonous bites, bowel complaints, epilepsy and also for blackening the hair (Nadkarni, 1954; Dey, 1980). The important formulations using the root and fruit are Abhayarista, Mahatiktakam kasaya, Manasamitravatakam, Cavikasava, Madhuyastyadi taila, etc. (Sivarajan et al, 1994). The powder is often used as an insecticide. The extract should never be given without some aromatic to correct its griping tendency (Nadkarni, 1998).

Fruit contains a glycoside- colocynthin, its aglycone- -elaterin, citrulluin, citrullene and citrullic acid. Unripe fruit contains p-hydroxy benzyl methyl ester. Roots contain - elaterin and hentriacontane (Husain et al, 1992). Colocynth is, in moderate doses, drastic, hydrogogue, cathartic and diuretic. In large doses, it is emetic and gastro-intestinal irritant and in small doses, it is expectorant and alterative. Colocynthin is a cathartic and intensely bitter principle. It has a purgative action. All parts of the plant are very bitter. The fruit has been described as cathartic (Nadkarni, 1982).

9. Citrullus vulgaris Schrad. syn. C. lanatus (Thunb.) Mats. & Nakai.

Eng: Water melon; San: Tarambuja;

Hin: Tarbuj;

Ben: Tarbuz

Mal: Thannimathan;

Tam: Pitcha, Dharbusini

Watermelon is an extensively climbing annual which is largely cultivated throughout India and in all warm countries. It has thick angular branching stems. Tendrils are bifid, stout and pubescent. Leaves are long, deeply divided or moderately lobed, glabrous or somewhat hairy and hardly scabrous. Petiole is a little shorter than the limb and villous. Calyx-lobes are narrowly lanceolate, equalling the tube. Corolla is yellow within, greenish outside and villous. Lobes are ovate-oblong, obtuse and prominently 5-nerved. Fruit is sub-globose or ellipsoid, smooth, greenish or clouded, often with a glaucous waxy coating. Flesh is juicy, red or yellowish white. Seeds are usually margined. C. vulgaris var. fistulosus Duthie & Fuller. syn. C. fistulosus has its fruit about the size of small turnip, the seeds of which are used medicinally. The fruit is tasteless when unripe and sweet when ripe. The unripe fruit is used to cure jaundice. Ripe fruit cures kapha and vata and causes biliousness. It is good for sore eyes, scabies and itching. The seeds are tonic to the brain and used as a cooling medicine. An emulsion of the seeds is made into a poultice with the pounded leaves and applied hot in cases of intestinal inflammations (Kirtikar and Basu, 1988). Fruit juice is good in quenching thirst and it is used as an antiseptic in typhus fever with cumin and sugar. It is used as a cooling drink in strangury and affections of urinary organs such as gonorrhoea; in hepatic congestion and intestinal catarrh. The bitter watermelon of Sind is known as “Kirbut” and is used as a purgative.

Seeds yield a fixed oil and proteids; citrullin. Seeds are cooling, demulcent, diuretic, vermifuge and nutritive. Pulp is cooling and diuretic. Fruit-juice is cooling and refreshing (Nadkarni, 1982).

10. Curcurbita pepo Linn. syn. Pepo vulgaris et P. verrucosus Moench

Meth.

Eng: Pompion, Pumpkin, Vegetable Marrow; San: Karkaru, Kurkaru, Kushmandi

Hin,

Ben: Kadimah, Konda, Kumra, Safedkkadu;

Mal: Mathan, Matha

Tel: Budadegummadi, Pottigummadi

Pompion or Pumpkin is a climbing herb which is considered to be a native of America and cultivated in many parts of India. The stem and leaves are with a harsh prickly armature. Foliage is stiff, more or less rigid and erect. Leaves are with a broad triangular pointed outline and often with deep lobes. Corolla is mostly with erect or spreading (not drooping) pointed lobes, the tube narrowing towards the base. Peduncle is strongly 5-angled and little or much expanding near the fruit. The fruit is cooling and astringent to the bowels, increases appetite, cures leprosy, ‘kapha and vata’, thirst, fatigue and purifies the blood. The leaves are used to remove biliousness. Fruit is good for teeth, throat and eyes and allays thirst. Seeds cure sore chests, haemoptysis, bronchitis and fever. It is good for the kidney and brain. The leaves are used as an external application for burns. The seeds are considered anthelmintic. The seeds are largely used for flavouring certain preparations of Indian hemp, and the root for a nefarious purpose, viz., to make the preparation more potent. The seeds are taeniacide, diuretic and demulcent. The fruit is cooling, laxative and astringent. The leaves are digestible, haematinic and analgesic.

The other important species belonging to the genus Cucurbita is C. maxima Duchena, the seeds of which are a popular remedy for tape-worm and oil as a nervine tonic (Kirtikar & Basu, 1988).

11. Corallocarpus epigaeus Benth. ex Hook. f. syn. Bryonia epigaea Wight.

San: Katunahi;

Hin: Akasgaddah;

Mal: Kadamba, Kollankova

Tam: Akashagarudan, Gollankovai;

Tel: Murudonda, Nagadonda

Corallocarpus is a prostrate or climbing herb distributed in Punjab, Sind, Gujarat, Deccan, Karnataka and Sri Lanka. It is monoecious with large root which is turnip-shaped and slender stem which is grooved, zigzag and glabrous. Tendrils are simple, slender and glabrous. Leaves are sub-orbicular in outline, light green above and pale beneath, deeply cordate at the base, angled or more or less deeply 3-5 lobed. Petiole is long and glabrous. Male flowers are small and arranged at the tip of a straight stiff glabrous peduncle. Calyx is slightly hairy, long and rounded at the base. Corolla is long and greenish yellow. Female flowers are usually solitary with short, stout and glabrous peduncles. Fruit is stalked, long, ellipsoid or ovoid. Seeds are pyriform, turgid, brown and with a whitish corded margin. It is prescribed in later stages of dysentery and old veneral complaints. For external use in chronic rheumatism, it is made into a liniment with cumin seed, onion and castor oil. It is used in case of snakebite where it is administered internally and applied to the bitten part. The root is given in syphilitic rheumatism and later stages of dysentery. The plant is bitter, sweet, alexipharmic and emetic. The root is said to possess alterative and laxative properties (Kirtikar and Basu, 1988). Root contains a bitter principle like Breyonin (Chopra et al, 1980).

Agrotechnology: Cucurbits can be successfully grown during January-March and September- December. For the rainfed crop, sowing can also be started after the receipt of the first few showers.

Pits of 60cm diameter and 30-45cm depth are to be taken at the desired spacing. Well rotten FYM or vegetable mixture is to be mixed with topsoil in the pit and seeds are to be sown at 4-5/pit. Unhealthy plants are to be removed after 2 weeks and retained 2-3 plants/pit. FYM is to be applied at 20-25t/ha as basal dose along with half dose of N (35kg/ha) and full dose of P (25kg) and K (25kg). The remaining dose of N (35kg) can be applied in 2 equal split doses at fortnightly intervals. During the initial stages of growth, irrigation is to be given at an interval of 3-4 days and at alternate days during flowering and fruiting periods. For trailing cucumber, pumpkin and melon, dried twigs are to be spread on the ground. Bitter gourd, bottle gourd, snake gourd and ash gourd are to be trailed on Pandals. Weeding and raking of the soil are to be conducted at the time of fertilizer application. Earthing up may be done during rainy season. The most dreaded pest of cucurbits is fruit flies which can be controlled by using fruit traps, covering the fruits with polythene, cloth or paper bags, removal and destruction of affected fruits and lastly spraying with Carbaryl or Malathion 0. 2% suspension containing sugar or jaggery at 10g/l at fortnightly intervals after fruit set initiation. During rainy season, downy mildew and mosaic diseases are severe in cucurbits. The former can be checked by spraying Mancozeb 0.2%. The spread of mosaic can be checked by controlling the vectors using Dimethoate or Phosphamidon 0.05% and destruction of affected plants and collateral hosts. Harvesting to be done at least 10 days after insecticide or fungicide application (KAU,1996).... cucurbits

Solanum spp.

Solanaceae

Solanums comprise a very important group of medicinal plants having multifarious uses.

These plants belong to the family Solanaceae and genus Solanum. A number of species are reported to be medicinal which are briefly described below.

1. S. anguivi Lam. syn. S. indicum auct. non Linn.

Eng: Poison berry; San: Brhati, Simhi;

Hin: Barhauta, Birhatta;

Mal: Puthirichunda, Cheruchunda;

Tam: Karimulli, Puthirichundai;

Kan: Ramagulla;

Tel: Cittimulaga, Tellamulaka It is found throughout the tropics, in plains and at low elevations. It is much branched, very prickly undershrub, 0.3-1.5m in height. Leaves are simple, large, ovate, subentire, sinuate or lobed. Flowers are blue in extra-axillary cymes having stellately hairy and prickly peduncles. Fruits are globose berries, reddish or dark yellow with smooth or minutely pitted seeds. Its roots are useful in vitiated conditions of vata and kapha, odontalgia, dyspepsia, flatulence, colic, verminosis, diarrhoea, pruritus, leprosy, skin diseases, strangury, cough, asthma, bronchitis, amenorrhoea, dysmenorrhoea, fever, cardiac disorders and vomiting. Roots bitter, acrid, astringent, thermogenic, anodyne, digestive, carminative, anthelmintic, stomachic, constipating, resolvent, demulcent, depurative, diuretic, expectorant, aphrodisiac, emmenagogue, febrifuge and cardiotonic.

2. S. dulcamara Linn.

Eng: Bittersweet, Bitter night shade; San: Kakmachi; Pun: Rubabarik It is found in tropical situations in India and Sikkim. The plant is rich in alkaloidal glycosides like solamarine, tomatidenol, solasodine and soladulcine. The berry and twig are alterative, antisyphilitic, diaphoretic, resolvent, narcotic, diuretic, antirheumatic and used in liver disorders and psoriasis.

3. S. erianthum D. Don, syn. S. verbascifolium auct. non Linn.

San: Vidari;

Hin: Asheta;

Mal: Malachunda;

Tam: Malaichundai, Anaisundaikkai

Pun: Kalamena;

Tel: Rasagadi

The plant is distributed over the tropical and subtropical zones of India. The plant contains alkaloids and steroidal sapogenins. Leaves and fruits contain solasodine, solasodiene, solafloridine, diosgenin, vespertilin and pregnenolone. The plant is CNS depressant, antiinflammatory and useful in burns.

4. S. melongena Linn.

Eng: Brinjal, Egg plant; San: Varttaki;

Hin: Bengan, Badanjan;

Mal: Vazhuthina

Tam: Kattirikkai;

Kan: Badanekaya, Doddabadane;

Tel: Vankaya, Niruvanga

It is mainly cultivated as a vegetable throughout the tropics and subtropics. It is an erect or suffrutescent, herbaceous, armed or unarmed perennial shrub. Leaves are simple, large, entire and lobed. Flowers are blue, in clusters of 2-5. Fruits are large, white, yellow or dark purple berries of different shapes capped with thick persistent calyx. Seeds are many, yellow or cream and discoid. The roots, leaves and unripe fruits are useful in cholera, bronchitis, asthma, odontalgia and fever. The roots are laxative, analgesic and cardiotonic. Leaves are sialagogue, narcotic and antiherpetic. The unripe fruits are bitter, acrid, sweet, aphrodisiac, cardiotonic and haematinic.

5. S. melongena var. incanum (Linn.) Prain syn. S. incanum Linn., S. coagulens Forsk.

San: Brihati;

Hin: Baigan;

Mal: Cheruvazhuthina

It is a herbaceous prickly plant found in warm humid tropics. It is grown almost throughout the year in the plains and during summer on the hills. It grows 0.6-2m in height. Leaves are simple, alternate lobed. Flowers are blue or white, 5 lobed, calyx with spines. Fruits are ellipsoid berries. The plant is a constituent of the dasamoola which helps to overcome vitiated tridoshas and cures dyspepsia, fever, respiratory and cardiac disorders, skin ailments, vomiting, ulcers and poisonous affections. In Ayurveda the formulations like Brihatyadi Kashaya, dashamoolarishta, Indukantaghritam, Dasamoolaharithaki, etc are the important preparations with the roots. It is also used in the treatment of toothache and sore throat. The fruit is reported to stimulate the intrahepatic metabolism of cholesterol. Roots are antiasthmatic and stimulant. Leaves are used in cholera, bronchitis and asthma. Fruits are useful in liver complaints.

6. S. nigrum Linn. syn. S. rubrum Mill.

Eng: Black night shade; San: Kakamachi;

Hin: Makoy, Gurkkamai;

Mal: Karimthakkali;

Tam: Manathakkali, Milagutakkali;

Kan: Kakarndi;

Tel: Kamachi, Kachi

It is seen wild throughout India. It is an erect, divaricately branched, unarmed, suffrutescent annual herb. Leaves are ovate or oblong, sinuate-toothed or lobed and glabrous. Flowers are 3-8 in extra-axillary drooping subumbellate cymes. Fruits are purplish black or reddish berries. Seeds are many, discoid, yellow, minutely pitted. The whole plant is useful in vitiated conditions of tridosha, rheumatalgia, swellings, cough, asthma, bronchitis, wounds, ulcers, flatulence, dyspepsia, strangury, hepatomegaly, otalgia, hiccough, opthalmopathy, vomiting, cardiopathy, leprosy, skin diseases, fever, splenomegaly, haemarrhoids, nephropathy, dropsy and general debility. The plant is bitter, acrid, emollient, antiseptic, antiinflammatory, expectorant, anodyne, vulnerary, digestive, laxative, diuretic, cardiotonic, depurative, diaphoretic, febrifuge, rejuvenating, sedative, alterant and tonic.

7. S. spirale Roxb.

Hin: Munguskajur

It is seen wild in Assam and Khasi hills in India. Its root is diuretic and narcotic.

8. S. stramoniifolium Jacq., syn. S. ferox auct. non Linn.

San: Garbhada;

Hin: Rambaigan;

Mal: Anachunda;

Tam: Anaichundai;

Tel: Mulaka

It is observed in India in the states of Assam, Maharashtra, Karnataka and Tamil Nadu. Its berries contain glycoalkaloids such as solasonine and solasodine. Its roots and berries are bechic, antiasthmatic, antirheumatic, antiviral, anticancerous and spermicidal.

9. S. surattense Burm. F. syn. S. xanthocarpum schrad. & Wendl., S. jacquinii Willd.

Eng: Yellow-berried nightshade; San: Kantakari, Nidigdhika;

Hin: Remgani,Kateli;

Mal: Kantakarichunda;

Tam: Kantankattiri;

Kan: Nelagulli;

Tel: Callamulaga

It is found throughout India and Pakistan in dry situations as weed on roadsides and wastelands. It is prickly, diffuse, bright green, suffrutescent, perennial undershrub, with zigzag branches. Leaves are ovate-oblong, hairy on both sides and armed on the midrib and the nerves. Flowers are bluish purple, in extra-axillary cymes. Fruits are glabrous, globular drooping berry, yellow or white with green veins, surrounded by the calyx. Seeds are many, small, reniform, smooth and yellowish brown.

The whole plant is useful in vitiated conditions of vata and kapha, helminthiasis, dental caries, inflammations, flatulence, constipation, dyspepsia, anorexia, leprosy, skin diseases, hypertension, fever, cough, asthma, bronchitis, hiccough, lumbago, haemorrhoids and epilepsy. The plant is bitter, acrid, thermogenic, anthelmintic, antiinflammatory, anodyne, digestive, carminative, appetiser, stomachic, depurative, sudorific, febrifuge, expectorant, laxative, stimulant, diuretic, rejuvenating, emmenagogue and aphrodisac. Fruits contain solasonine, solamargine and solasodine.

10. S. torvum Sw.

Eng: West Indian Turkey Berry;

Hin,

Ben: Titbaigan;

Mal: Kattuchunda;

Kan: Kadu Sunde;

Tam: Sundaikai, Amarakai;

Tel: Kundavustic, Kotuvestu; Ass: Hathibhekuri

It is seen throughout tropical India, particularly in Orissa, Bihar and Manipur. The plant is CVS active and used in splenomegaly. Fruits and leaves contain solasonine, solasodine, jurubine, jurubidine, torvonin, torvogenin, chlorogenin, paniculogenin, sisalogenone, neosolaspigenin and solaspigenin.

11. S. trilobatum Linn.

Eng: Climbing Brinjal; San: Alarka;

Mal: Tutavalam;

Tam: Tuduvalai;

Kan: Mullumusta;

Tel: Telavuste

It is mostly seen in South and Western India. The plant contains alkamine and solamarine. The berry and flowers are bechic and used in bronchitis. The alkaloid solamarine is antibiotic and possesses antitumour activity.

12. S. viarum Dunal, syn. S. Khasianum C. B. Clarke

Hin: Kantakari

It is widely distributed in Khasi, Jaintia and Naga hills of Assam and Manipur upto 2000m and in Sikkim, West Bengal, Orissa and in the Niligiris. The plant and berries contain solasonine (which on hydrolysis yields solasodine), solamargine, khasianine, nantigenin, solasodine, diosgenin and saponin-solakhasianin. The plant is spasmolytic and CNS active. The berry is a source of solasodine used in the synthesis of corticosteroidal hormones.

Agrotechnology: The agrotechnology for the solanaceous group of plants are almost similar. They come up very well in tropical and subtropical climate upto 2000m altitude. They can be raised on a variety of soils good in organic matter. Propagation is by seeds. The seedlings are first raised in the nursery and transplanted to the main field 30-45 days after sowing when the plants attain 8-10cm height. During rainy season, planting is done on ridges while during summer in furrows, at a spacing ranging from 30-90cm depending upon the stature and spreading habit of the plant. The transplanted seedlings should be given temporary shade for 2-4 days during summer. FYM or compost at 20-25t/ha is applied at the time of land preparation. A moderate fertiliser dose of 75:40:40 N, P2O5, K2O/ha may be given. P is given as basal dose, N and K are applied in 2-3 split doses. One or two intercultural operations are needed to control weeds. The plants need earthing up after weeding and topdressing. Irrigation is needed at 3-4 days interval during summer and on alternate days during fruiting period. Plants need staking to avoid lodging due to heavy bearing. Shoot borers, mealy bugs, leaf webbers and miners are noted on the crop, which can be controlled by spraying mild insecticides. Root knot nematode, wilting and mosaic diseases are also noted on the crop. Field sanitation, crop rotation and burning of crop residues are recommended.... solanums

Betel nut. Areca catechu L. German: Areka palme. French: Noisette d’inde. Italian: Palma arec. Chinese: Ping-lang. Part used: seed. Chewing nut of the Far East.

Action: taenicide, astringent, stimulant. In absence of other remedies may be used for tape-worm. Use confined to veterinary medicine. Hardens soft gums. Treatment: for helminthiasis in dogs. To expel tape worms.

Preparations: Areca powder: dose, 1-4g. Liquid Extract; dose, 1-4ml. Thrice daily. ... areca nut

Allium sativum

Liliaceae

San: Lasunah, Rasonah;

Hin:Lasun, Lahasun;

Ben: Lashan;

Mal: Vellulli;

Kan: Belluli;

Tam: Vellaipuntu; Mar: Lasunas; Ass: Naharu; Tel:Vellulli, Tella-gadda;

Guj: Lasan

Importance: Garlic is one of the important bulb crops used as a spice or condiment with medicinal value throughout the world. It possesses high nutritive value. Its preparations are useful in vitiated conditions of kapha and vata, cough, whooping cough, bronchitis, asthma, fever, facial paralysis, flatulence, colic, constipation, atonic dyspepsia, helminthiasis, duodenal ulcers, pulmonary and laryngeal tuberculosis, opthalmopathy, cardiopathy, fatigue, leucoderma, leprosy, hysteria, haemorrhoids, sciatica, otalgia, lumbago, swellings, splenopathy, hepatopathy, pneumonopathy, anthralgia, sore eyes, ear ache and dental caries (Kumar et al, 1997).

Distribution: Garlic is a native of Southern Europe and it is cultivated all over the world.. It is grown throughout India; Gujarat and Orissa being the leading states.

Botany: The genus Allium of Liliaceae family comprises a number of species. The important ones are the following:

A. sativum Linn. syn. A. porrum Linn.

A. cepa Linn.

A. ampeloprasum Linn.

A. ascalonicum Linn. A. leptophyllum Wall. A. macleanii Baker.

A. schoenoprasum Linn.

A. tuberosum Roxb.

Allium sativum is a scapigerous foetid perennial medicinal herb with underground compound bulbs covered over by outer white thin scales and with simple smooth, round stem, surrounded at the bottom by tubular leaf sheath. The leaves are simple, long, flat and linear. The flowers are small and white arranged in rounded umbels mixed with small bulbils. The entire umbel is enclosed in a tear-drop-shaped membranous spathe. Flowers are usually sterile (Warrier et al, 1993).

Agrotechnology: Garlic can be grown under a wide range of climatic conditions. It prefers moderate temperature in summer as well as in winter. Short days are very favourable for the formation of bulbs. Garlic requires well drained loamy soils rich in humus, with fairly good content of potash. Garlic is propagated by cloves or bulblets. In the hills, sowing is done in April and May. Types with bold and compact cloves and thick white covering sheath are preferred for planting. Ootty-1 garlic is an improved variety by clonal selection released from TNAU, Coimbatore. Garlic may be broadcast, planted in furrows or dibbled at the rate of 150-200kg cloves/ha. In furrow planting, cloves are dropped 7.5-10cm apart in furrows 15cm deep and covered lightly with loose soil. Cloves may be dibbled 5 to 7.5cm deep and 7.5cm apart in rows which are 15cm apart with their growing end upwards and then covered with loose soil. A basal dose of 60kg N and 50kg each of P2O5 and K2O are applied along with 25t/ha of FYM. 60kg N is given as topdressing 45 days after planting. First irrigation is given immediately after sowing and subsequent irrigations are given at 10-15 days interval depending upon the soil moisture availability. The last irrigation should be given 2-3 days before harvesting to facilitate easy harvest and minimum damage to bulbs. First weeding and hoeing is to be done at one mo nth after sowing followed by a second weeding one month after first interculture. Hoeing at about two and a half months from sowing loosens the soil and helps in setting of bigger and well-filled bulbs. Garlic is attacked by Thrips tabacii which causes withering of leaves. Application of methyl demeton 25EC or dimethoate 30EC at 1ml/l will check the pest incidence. Leaf spot caused by Alternaria solanii can be controlled by spraying Dithane M.45 at fortnightly intervals at 2.5g/l of water. Garlic is harvested when the tops turn yellowish or brownish and show signs of drying up. The plants are uprooted, tied into small bundles and kept in shade for 2-3 days for curing. Average yield of garlic is 6-8t/ha. (Kumar et al, 1997.)

Properties and activity: Garlic bulb is reported to contain volatile oil, alliin (S-allyl-L-cysteine sulfoxide), S-methyl-L-cysteine sulfoxide and allinase. It is rich in vitamins like thiamine, riboflavine and niacin. Volatile oil contains allicin (diallyl thiosulphinate), an active odour principle of garlic. Other major compounds present are diallyl disulphide, diallyl trisulphide, allyl methyl trisulphide and allyl methyl disulphide (Husain et al., 1992).

Garlic bulb is antirheumatic, stimulant, diaphoretic, expectorant, diuretic, antispasmodic, astringent, antiparalytic, antileprotic, aperient, febrifuge, carminative, stomachic, alterative and emmenagogue. The essential oil is hypocholestrolemic, hypotensive, antitumour and antidiabetic. Diallyl disulphide and diallyl trisulphide from essential oil have larvicidal action. Bulbs also have anti-bacterial, and anti-fungal activity.... garlic

Gloriosa superba

Liliaceae

San: Langali, Visalya, Agnishika,Shakrapushpi, Garbhaghatini

Hin: Kalihari

Mal: Menthonni

Tam: Akkinichilam

Pan: Kariari

Guj: Dudhiya vachnag

Kan: Nangulika Mar: Nagakaria

Ben: Bishalanguli Ori: Dangogahana

Tel: Adavinabhi

Importance: Glory lily is a glabrous herbaceous climber which yields different types of troplone alkaloids of medicinal importance. The major alkaloids are colchicine , 3-demethyl colchicine and colchicoside. There is another alkaloid gloriosine which promises to be even more effective than colchicine in plant breeding for inducing polyploidy. The genus has importance in the ornamental horticulture due to its bright flowers and wiry climbing stem.

The roots and rhizomes are used in traditional system of medicine. Its abortifacient and antipyretic properties have been mentioned in ancient classics “Charaka”. The name Garbhaghatini is due to this abortifacient activity. They are useful in the treatment of inflammations, ulcers, scrofula, hemorrhoids, pruritus, dyspepsia, helminthiasis, flatulence, intermittent fevers and debility. The root is given internally as an effective antidote against cobra poison. A paste of the root is also used as an anodyne; applications in bites of poisonous insects, snake bites, scorpion sting, parasitic skin diseases and leprosy (Nadkarni,1954; Chaudhuri and Thakur; 1994).

Distribution: The plant is distributed throughout tropical India upto an altitude of 2500m and in Andaman islands. It is also cultivated in tropical and South Africa, Madagaskar, Indonesia and Malasia. It is reported to be cultivated in some parts of Europe. In India it was cultivated in RRL, Jammu in 1960s. Recently it was taken up by Indian Council of Agricultural Research(ICAR). Cultivation of the plant is mostly confined to the Southern states of India besides its collection from wild sources.

Botany: Gloriosa superba Linn. belongs to Liliaceae family. It is a glabrous climbing herb with tuberous root stock grows over hedges and small trees. Stem is 6m long which grows to a height of 1.2-1.5m before the stem branches. Leaves are simple, alternate or whorled, sessile, ovate-lanceolate, 17x4.5cm, tip elongating into a spirally coiled tendril, base cordate and margin entire. Flowers are large in terminal racemes; perianth segments 6, linear, flexuosus and deflexed, basal half bright yellow, upper half red; stamens 6; ovary glabrous, 3-celled. Fruits are capsules, linear-oblong, upto 6.8cm long, 3 equal lobes, one or two lobes shorter in malformed fruits; green dried to pale and then black colour, dehisced into three sections. Seeds are oval in shape, testa spongy, embryo cylindric, 30-150 seeds per capsule, pale orange attached to the sutures. Tubers are cylindric, large, simple, ‘V’ shaped with the two limps equal or unequal in lenth pointed towards end brownish externally and yellowish internally. (Narain, 1977)

Agrotechnology: This is a rainy season plant and sprouts well in warm, humid and tropical conditions. It should be grown in sun as the plants in shade become weedy and thin and move towards light. G. superba is a shallow rooted plant and grows well in a variety of soils either clay or sand through out India. It grows well in a light porous soil with good drainage. For vigorous growth, greater blooms and strong tuber, a mixture of soil, sand and compost manure is recommended. The propagation is mainly by tubers, by division of rhizomes. Seeds remain dormant for 6-9 months and due to hard seed coat, about 20-30 days are required for germination and seeds may take 3-4 years before it matures to flower. Treatment of seeds by gibberellin(1-3 ppm) resulted in higher yield of colchicine in the plant and higher production of tubers. In tissue culture, young sprouts are cultured on Murashige and Skoog’s medium (Msb) supplemented with kinetin (1-4 mg/l). Direct regeneration of the explants are obtained.

The seeds and rhizomes are sown usually in the last week of June to mid July. The rhizomes are planted by splitting carefully into two from their ‘V’ shaped joints (two buds being at the extreme end of each rhizome) in lines 20cm apart at a distance of 20cm (while seeds are sown in lines at a distance of 4-6cm apart). They are watered regularly when the plants are growing. After green shoots appear 2-3 showers are weekly. The irradiation of the plant at 42% natural sunlight intensity increased the production of tuber and colchicine. They usually takes 6-10 weeks to flower after sprouting and then set on fruits. The fruits ripen at the end of October and after that aerial shoot eventually dies, leaving the fleshy tubers underground. The tubers are dug out with great care. An individual plant produces 50g tubers on an average. The average yield is approximately 4000-5000kg of rhizomes and 1000 kg of seed per hectare. The content of colchicine is usually 0.358% and 1.013% in tubers and seeds, respectively.

Post harvest technology: Lixivation of the material is done with 70% ethyl alcohol. Concentrated under vacuum to one third of its volume and extracted with chloroform for colchicine and related substances-concentration of the aqueous phase to syrup which is extracted 6-8 times with a mixture of CHCl3 - alcohol (4:1) to yield colchicoside.

Properties and activity: The flowers, leaves and tubers contain colchicine, superbin, N-formyl deacetyl colchicine, demethyl colochicine and lumicolchicine. Tubers also contain gloriosine. Leaves in addition, contain chelidonic acid, 2-hydroxy 6-methoxy benzoic acid and -sitosterol glucoside. Colchicine, demethyl colchicine and colchicoside have been reported from seeds. Rhizome is oxytocic, anticancerous, antimalarial, stomachic, purgative, cholagogue, anthelmintic, alterative, febrifuge and antileprotic. Leaf is antiasthmatic and antiinflammatory. Root shows antigonorrhoeic and antibiotic activity. This plant has poisonous effect to enviroment and livestock. The toxic properties are due to presence of alkaloids chiefly colchicine (Clewer et al, 1915).... glory lily

Gymnema sylvestre

Asclepiadaceae

San: Mesasrngi, Madhunasini;

Hin: Gudmar, Merasimgi;

Ben: Merasingi;

Mal: Chakkarakolli, Madhunasini;

Tam: Sirukurumkay, Sakkaraikkolli;

Kan: Kadhasige;

Tel: Podapatra; Mar: Kavali

Importance: Gymnema, Australian Cowplant, Small Indian Ipecacuanha or Periploca of the woods is a woody climber. It is reported to cure cough, dyspnoea, ulcers, pitta, kapha and pain in the eyes. The plant is useful in inflammations, hepatosplenomegaly, dyspepsia, constipation, jaundice, haemorrhoids, strangury, renal and vesical calculi, helminthiasis, cardiopathy, cough, asthma, bronchitis, intermittent fever, amenorrhoea, conjuctivitis and leucoderma. The fresh leaves when chewed have the remarkable property of paralysing the sense of taste for sweet and bitter substance for some time (Warrier et al, 1995). The drug is described as a destroyer of madhumeha (glycosuria) and other urinary disorders. Root has long been reputed as a remedy for snakebite. Leaves triturated and mixed with castor oil are applied to swollen glands and enlargement of internal viscera as the liver and spleen (Nadkarni, 1954). The drug is used to strengthen the function of heart, cure jaundice, piles, urinary calculi, difficult micturition and intermittent fevers (Sharma,1983). The drug enters into the composition of preparations like Ayaskrti, Varunadi kasaya, Varunadighrtam, Mahakalyanakaghrtam, etc. They suppress the activity of taste of tongue for sweet taste and for this reason it was considered that it destroys sugar, hence the name Madhunashini or Gurmar and has been prescribed as an anti-diabetic. The crude drug as well as its dried aqueous extract is mainly used in bronchial troubles.

Distribution: It is a tropical climber. It mainly grows in Western Ghats, Konkan, Tamil Nadu and some parts of Bihar. The plant is cultivated in plains of India but the drug is mainly important from Afghanistan and Iran.

Botany: Gymnema sylvestre (Retz.)R. Br. syn. Asclepias germinata Roxb. belonging to the family Asclepiadaceae is a large, woody much branched climber with pubescent young parts. Leaves are simple, opposite, elliptic or ovate, more or less pubescent on both sides, base rounded or cordate. Flowers are small, yellow and arranged in umbellate cymes. Fruits are slender and follicles are upto 7.5cm long (Warrier et al, 1995).

Two allied species, G. hirsutum found in Bundelkh and Bihar and Western Ghats and G. montanum growing wild in Eastern Ghats and Konkan are also used for the same purpose and are also called “Gurmar” (Thakur et al, 1989).

Agrotechnology: The plant can be propagated both by seeds and stem cuttings. Seedlings are to be raised in polybags. Pits of size 50cm cube are to be taken, filled with 10kg dried cowdung or FYM and covered with topsoil. On these pits about 3-4 months old seedlings are to be transplanted from polybags. Trailing can be facilitated by erecting poles and tying the plants to the poles. The plant will attain good spread within one year. Regular weeding, irrigation and organic manure application are beneficial. The plant is not attacked by any serious pests or diseases. Leaves can be collected from the first year onwards at an internal of one week. This can be continued for 10-12 years. Fresh or dried leaves can be marketed (Prasad et al, 1997).

Properties and activity: Nonacosane and hentriacontane were isolated from the hexane extract of leaves. An attempt to isolate nitrogenous compounds led to the isolation of amino acids such as leucine, iso-leucine, valine, allanine and - amynobutyric acid. Isolation of trimethyl amine oxide was of particular interest. An alkaloid gynamine which is a trace constituent was isolated and identified (Sinsheimer et al, 1967). Antisweet constituent of the leaves has been found to be a mixture of triterpene saponins. These have been designated as gymnemic acids A,B,C and D which have the gymnemagenin and gymnestrogenins as the aglycones of gymnemic acid A and B and gymnemic acid C and D respectively. These are hexahydroxy triterpenes the latter being partially acylated. The sugar residues are glucuronic acid and galacturonic acid while ferulic and angelic acids have been attached as the carboxylic acid.

Chewing of leaves reduces sensitivity to sweet substances. Effects of gymnema extracts had been variable. While verifying the effect of G. sylvestre leaves on detoxification of snake venom, it has been reported that a toxic component of venom ATP and gymnemate bind at the same site inhibiting venom ATP-ase. The active principles which have been identified as glycosides (7 gymnemic acids) suggest that the topical and selective anaesthetic effect of the plant might result from the competition of the receptor sites between glycosides and the sweet substances (Warren et al, 1969). The leaves are antidiabetic and insulinotropic. Gymnemic acid is antiviral. The plant is bitter, astringent, acrid, thermogenic, antiinflammatory, anodyne, digestive, liver tonic, emetic, diuretic, stomachic, stimulant, anthelmintic, alexipharmic, laxative, cardiotonic, expectorant, antipyretic and uterine tonic.... gymnema

Hemidesmus indicus

Asclepiadaceae

San: Anantamulah, Sariba;

Hin: Anantamul, Magrabu;

Ben: Anantamul;

Mal: Nannari, Naruninti, Narunanti;

Tam: Nannari, Saribam;

Tel: Sugandipala;

Kan: Namadaballi

Importance: Indian Sarasaparilla or Country Sarasaparilla is a climbing slender plant with twining woody stems and a rust-coloured bark. The roots are useful in vitiated conditions of pitta, burning sensation, leucoderma, leprosy, skin diseases, pruritus, asthma, bronchitis, hyperdipsia, opthalmopathy, hemicrania, epileptic fits, dyspepsia, helminthiasis, diarrhoea, dysentery, haemorrhoids, strangury, leucorrhoea, syphilis, abcess, arthralgia, fever and general debility. The leaves are useful in vomiting, wounds and leucoderma. The stems are bitter, diaphoretic and laxative and are useful in inflammations, cerebropathy, hepatopathy, nephropathy, syphilis, metropathy, leucoderma, odontalgia, cough and asthma. The latex is good for conjunctivitis (Warrier et al, 1995). The important formulations using the drug are Saribadyasava, Pindataila, Vidaryadi lehya, Draksadi kasaya, Jatyadi ghrita, etc. (Sivarajan et al, 1994). The Hemidesmus root powdered and mixed with cow’s milk is given with much benefit in the case of strangury. In the form of syrup, it has demulcent and diuretic proportions. The root, roasted in plantain leaves, then beaten into a mass with cumin and sugar and mixed with ghee is a household remedy in genito-urinary diseases. The hot infusion of the root-bark with milk and sugar is a good alterative tonic especially for children in cases of chronic cough and diarrhoea (Nadkarni, 1998). It has been successfully used in the cure of venereal diseases where American Sarasaparilla (Aralia nudicaulis Linn.) has failed. Native doctors utilize it in nephritic complaints and for sore mouths of children (Grieve and Leyel, 1992).

Distribution: Hemidesmus is distributed throughout India, the Moluccas and Sri Lanka.

Botany: Hemidesmus indicus (Linn.) R. Br. syn. Periploca indica Linn. belongs to the family Asclepiadaceae. It is a perennial, slender, laticiferous, twining or prostrate, wiry shrub with woody rootstock and numerous slender, terete stems having thickened nodes. Leaves are simple, opposite, very variable from elliptic-oblong to linear-lanceolate, variegated with white above and silvery white and pubescent beneath. Flowers are greenish purple crowded in sub-sessile cymes in the opposite leaf-axils. Fruits are slender follicles, cylindrical, 10cm long, tapering to a point at the apex. Seeds are flattened, black, ovate-oblong and coma silvery white. The tuberous root is dark-brown, coma silvery white, tortuous with transversely cracked and longitudinally fissured bark. It has a strong central vasculature and a pleasant smell and taste (Warrier et al, 1995).

The Ayurvedic texts mention two varieties, viz. a krsna or black variety and a sveta or white variety (Aiyer, 1951) which together constitute the pair, Saribadvayam. The drug is known as Sariba. Svetasariba is H. indicus. Two plants, namely, Ichnocarpus fructescens (Apocynaceae) known as pal-valli in vernacular and Cryptolepis buchanani (Asclepidaceae) known as Katupalvalli (Rheeds, 1689) are equated with black variety or Krsnasariba (Chunekar, 1982; Sharma, 1983).

Agrotechnology: Hemidesmus is propagated through root cuttings. The root cuttings of length 3-5cm can be planted in polybags or in the field. They can be planted in flat beds or on ridges. Planting is done usually at a spacing of 50x20cm. Heavy application of organic manure is essential for good growth and root yield. Inorganic fertilizers are not usually applied. Frequent weeding and earthing up are required, as the plant is only slow growing. Provision of standards for twining will further improve the growth and yield of the plant.

Properties and activity: The twigs of the plant give a pregnane ester diglycoside named desinine. Roots give -sitosterol, 2-hydroxy-4-methoxy benzaldehyde, -amyrin, -amyrin and its acetate, hexatriacontane, lupeol octacosonate, lupeol and its acetate. Leaves, stem and root cultures give cholesterol, campesterol, -sitosterol and 16-dehydro-pregnenolone. Leaves and flowers also give flavonoid glycosides rutin, hyperoside and iso-quercitin (Husain et al,1992). “Hemidesmine”- a crystallizible principle is found in the volatile oil extracted from roots. Some suggest that it is only a stearoptene. It also contains some starch, saponin and in the suberous layer, tannic acid (Grieve and Leyel, 1992). The root is alterative, febrifuge, antileucorrhoeic, antisyphilitic, demulcent, diaphoretic, diuretic, tonic, galactogenic, antidote for scorpion-sting and snake-bite, antidiarrhoeal, blood purifier, antirheumatic and aperitive. Essential oil from root is anti-bacterial and the plant is antiviral (Husain et al, 1992).... indian sarasaparilla

Cassia senna

Caesalpiniaceae

San: Svarnapatri;

Hin: Sanay, Sana Ka Patt;

Ben: Sonamukhi;

Mal: Sunnamukki, Chonnamukki, Nilavaka;

Tam: Nilavirai, Nilavakai;

Tel: Netatangedu

Importance: Indian Senna or Tinnevelly senna is a shrub very highly esteemed in India for its medicinal value. The leaves are useful in constipation, abdominal disorders, leprosy, skin diseases, leucoderma, splenomegaly, hepatopathy, jaundice, helminthiasis, dyspepsia, cough, bronchitis, typhoid fever, anaemia, tumours and vitiated conditions of pitta and vata (Warrier et al,1994). It is used in Ayurvedic preparations; “Pancha Sakara Churna”, “Shat Sakara Churna” and “Madhu Yastyadi Churna” used for constipation. Its use is widespread in Unani system and some of the important products of this system containing senna are “Itrifal Mulayyin”, “Jawarish Ood Mulayyin”, “Hab Shabyar”, “Sufuf Mulliyin”, “Sharbat Ahmad Shahi”, etc. used as a mild laxative (Thakur et al, 1989).

Distribution: The plant is of Mediterranean origin. It is found in Somalia, Saudi Arabia, parts of Pakistan and Kutch area of Gujarat. It is largely cultivated in Tirunelveli, Ramanathapuram, Madurai and Salem districts of Tamil Nadu.

Botany: The genus Cassia, belonging to the family Caesalpiniaceae, comprises of a number of species, namely,

C. senna Linn. syn. C. angustifolia Vahl.

C. absus Linn.

C. alata Linn.

C. auriculata Linn.

C. burmanni Wight. syn. C. obovata (Linn.) Collad.

C. glauca Lam.

C. javanica Linn.

C. mimosoides Linn.

C. obtusifolia Linn. syn. C. tora Linn.

C. occidentalis Linn.

C. pumila Lam.

C. slamea Lam.

C. acutifolia Delile.

C. sophera Linn.

C. senna is a shrub or undershrub, 60-75cm in height with pale subterete or obtusely angled erect or spreading branches. Leaves are paripinnate. Leaflets are 5-8 in number, ovate-lanceolate and glabrous. Flowers are yellowish, many and arranged in axillary racemes. Fruits are flat legumes, greenish brown to dark brown and nearly smooth (Chopra et al,1980, Warrier et al,1994).

In commerce, the leaves and pods obtained from C. senna are known as “ Tinnevelly Senna” and those from C. acutifolia Delile. as “Alexandrian Senna”. The leaves of C. acutifolia are narrower than C. senna, otherwise both resemble to a large extent (Thakur et al, 1989). All the true Sennas have the portions of their leaves unequally divided. In some kinds the lower part of one side is reduced to little more than a line in breadth, while the other is from a quarter to half an inch in breadth. The drug known under the name of East Indian Senna is nearly free from adulteration; and as its properties appear identical with those of the Alexandrian and the price being less, it probably will supersede it in general practice. Its size and shape readily identify it (Graves, 1996).

Agrotechnology: The plant requires a mild subtropical climate with warm winters which are free from frost for its growth. Semiarid areas with adequate irrigation facilities are ideal for cultivation. Areas having high rainfall, humidity and poor drainage are not suitable. Light or medium loamy soils with adequate drainage and pH varying from 7.0-8.2 are preferable. In South India both summer and winter crops are possible. The plant is propagated by seeds. The seed rate required is 15-20kg/ha. Seeds are sown in October-November (winter rainfed crop) or in February-March (irrigated crop). Higher seed rate is required for unirrigated crop. Seeds are sown in lines 30cm apart. Application of 5-10t of FYM/ha before planting or raising a green manure crop is beneficial. About 40kg N and 25-50kg P2O5/ha applied as basal dressing and 40kg N/ha applied in 2 split dozes as top dressing gave better yield. While the rainfed crop is grown without irrigation, the irrigated crop requires 5-8 light irrigations during the entire growing season. The crop requires 2-3 weedings and hoeings in order to keep it free from weeds. Alternaria alternata causes leaf spot and dieback but the disease is not serious. In North India, the plant is attacked by the larvae of butterfly Catopsilia pyranthe which can be controlled by planting the crop in March-April instead of June-July. Under irrigated conditions, the first crop is obtained after 90 days of planting. The leaves are stripped by hand when they are fully green, thick and bluish-green in colour. The second crop is taken 4 weeks after the first harvest and the third 4-6 weeks after the second one. The last harvest of leaves is done when the entire crop is harvested along with the pods. Yield under irrigated conditions is nearly1.4t of leaves and 150kg pods/ha and under unirrigated conditions is 500-600kg leaves and 80-100kg pods/ha. The leaves are dried in thin layers under shade so as to retain the green colour and the pods are hung for 10-12 days to get dried. The leaves and pods are cleaned, graded and marketed (Husain et al, 1993).

Properties and Activity: Leaves contain glucose, fructose, sucrose and pinnitol. Mucilage consists of galactose, arabinose, rhamnose and galacturonic acid. Leaves also contain sennoside-C(8,8’- diglucoside of rhein-aloe-emodin-dianthrone). Pods contain sennosides A and B, glycoside of anthraquinones rhein and chrysophanic acid. Seeds contain -sitosterol (Husain et al, 1992). Leaves and pods also contain 0.33% -sterol and flavonols-kaempferol, kaempferin, and iso-rhamnetin. Sennoside content of C. acutifolia is higher ranging from 2.5% to 4.5% as compared to C. angustifolia ranging from 1.5 % to 2.5%.

The purgative activity of Senna is attributed to its sennosides. The pods cause lesser griping than the leaves. Leaf and pod is laxative. The leaves are astringent, bitter, sweet, acrid, thermogenic, cathartic, depurative, liver tonic, anthelmintic, cholagogue, expectorant and febrifuge.... indian senna

Linn.

Family: Euphorbiaceae.

Habitat: Cultivated chiefly in Andhra Pradesh, Maharashtra, Karnataka, and Orissa.

English: Castor seed.

Ayurvedic: Eranda, Chitra- bija, Triputi; Tribija, Vaataari, Chanchu, Manda, Uruvaka, Gandharva-hastaa, Panchaan- gula, Vardhamaana, Uttaanpatraka, Vyaaghrapuchha, Chitraa.

Unani: Bedanjeer, Arand.

Siddha/Tamil: Ammanakku.

Action: Oil from seeds and young leaf—purgative. Oil is used in dermatosis and eczema. Leaves— used as poultice to extract the worm.

Root—a decoction is administered for lumbago and allied complaints.

Bark—purgative.

The Ayurvedic Pharmacopoeia ofIn- dia recommends the decoction of the dried, mature root in rheumatism, pain in the urinary bladder, lumbago, diseases of the abdomen and inflammations; fresh leaf in helminthiasis, dysu- ria, arthritis, pain in the urinary bladder, dysuria, abscesses; dried seed powder in constipation, rheumatism, diseases of the liver and spleen, piles, lumbago, sciatica.

The root extract exhibited significant anti-inflammatory activity against carrageenan-, bradykinin-, 5-HT-and dextran-induced rat hind paw oedema. N-Demethylricinine showed dose-dependent anticholestatic and hepato- protective activities in rats.

Castor oil, derived from the seeds, is a well-known purgative (dose 520 ml).

Castor seed contains toxic components (2.8-3.0% on whole seed; about 10% in the flour) which are highly poisonous to human beings and animals. The principal toxic substance is the albumin, ricin. Allergens and a feebly toxic alkaloid ricinine is also present. An ulcerative factor in the seed is reported. Like other toxalbumins, ricin agglutinizes the mammalian red bleed corpuscles. (Ricin loses its toxicity and antigenic action on treatment with potassium permanganate.)

Castor oil consists principally of ri- cinoleic acid. Stearic, oleic, linoleic and dihydroxystearic acids are present in small amounts. The strong laxative property of castor oil is reported due to the local irritant action caused in the intestines by ricinoleic acid formed by hydrolysis under the influence of lipolytic enzymes. (The oil should not be used with fat-soluble vermifuge, it may increase its absorption and toxic- ity.)

Dosage: Root—20-30 g for decoction. (API, Vol. I.) Leaf—10- 20 ml juice; 2-5 g powder; seed— 0.5-3 g powder. (API, Vol. III.)... ricinus communis

Linn.

Family: Taxaceae.

Habitat: Temperate Himalayas, Khasi Hills and Manipur.

English: European Yew. Himalayan Yew is equated with Taxus wal- lichiana Zucc., synonym T. baccata Linn. subspecies wallichiana (Zucc.) Pilgoe, T. baccata Hook. f.

Ayurvedic: Thunera, Sthauneya, Sthauneyaka, Shukapushpa, Dhaatri-patra, Vikarna. (Not a substitute for Taalisapatra.)

Unani: Zarnab.

Siddha/Tamil: Taaleespatri Bhedam.

Folk: Birmi, Thuno.

Action: Herb—CNS depressant; reduces motor activity; analgesic, anticonvulsant. Leaf used in nervousness, epilepsy, hysteria, asthma, chronic bronchitis. Leaf and fruit—antispasmodic, sedative, emmenagogue.

Berry—used in chronic bronchitis. Taxol—antimitotic; also being tried for the treatment of severe drug-resistant human malaria. (Chem Abstr, 1994, 21, 124674 j.) (The taxol content in Himalayan Yew varied with season and location from 0.045-0.130%.)

The needles contain diterpene esters of taxane-type (mixture is known as taxine 0.6-2.0%). Taxine consists of 11 compounds of which only tax- ine A and B have been characterized. Taxol, the diterpene amide, is found active against ovarian cancer in humans. (clinical results showed 24-30% response). The ester alkaloids in higher doses are cardiotoxic.

Dried needles contain biflavonoids, including sotetsuflavone, sequoifla- vone, sciadopitysin, ginkgetin, kayafla- vone, amentoflavone, beta-sitosterol, heptacosanol and surcose.

The needles gave several phenolics. Betuloside (rhododendron) exhibited hepatoprotective activity against hepa- totoxins in rats.

The seeds are poisonous and contain taxine.

The aqueous extract of leaves showed a depressant effect on the central nervous system in rats.

The Ayurvedic Pharmacopoeia ofIn- dia attributed antirheumatic, anticatar- rhal, insecticidal and wound-healing properties to the dried needles of Himalayan Yew and indicated the use of the drug in powder form (1-3 g) in disorders due to vitiated blood, tumours, dermatosis and helminthiasis.

Dosage: Leaf—1-3 g powder. (API, Vol. III.) Leaf, bark—3-5 g powder. (CCRAS.)... taxus baccata

Acorus calamus

Araceae

San: Vaca, Ugragandha, Bhadra;

Hin: Bacc, Gorbacc;

Ben: Bach; Mal:Vayampu;

Tam: Vasampu;

Kan: Bajai;

Tel: Vasa Vadaja

Importance: The sweet flag is an important medhya drug, capable of improving memory power and intellect. It is used in vitiated conditions of vata and kapha, stomatopathy, hoarseness, colic, flatulence, dyspepsia, helminthiasis, amenorrhoea, dismenorrhoea, nephropathy, calculi, strangury, cough, bronchitis, odontalgia, pectoralgia, hepatodynia, otalgia, inflammations, gout, epilepsy, delirium, amentia, convulsions, depression and other mental disorders, tumours, dysentery, hyperdipsia, haemorrhoids, intermittent fevers, skin diseases, numbness and general debility. It is reportedly useful in improving digestion, clearing speech and curing diarrhoea, dysentery, abdominal obstruction and colic. It is also useful in infantile fever, cough bronchitis and asthma. The drug is reported to cure hysteria, insanity and chronic rheumatic complaints. The rhizome is an ingredient of preparations like Vacaditaila, Ayaskrti, Kompancadi gulika, Valiya rasnadi kashaya, etc.

Distribution: The plant is a native of Europe. It is distributed throughout the tropics and subtropics, especially in India and Sri Lanka. It is found in marshes, wild or cultivated, ascending the Himalayas upto 1800m in Sikkim. It is plentiful in marshy tracts of Kashmir and Sirmoor, in Manipur and Naga Hills.

Botany: Acorus calamus Linn. belonging to the family Araceae is a semi -aquatic rhizomatous perennial herb. Rhizome is creeping, much branched, cylindrical or slightly compressed, light brown or pinkish brown externally, white and spongy within. Leaves are bright green, distichous, ensiform, base equitant, thickened in the middle and with wavy margins. Flowers are light brown and densely packed in sessile cylindric spadix. Fruits are oblong, turbinate berries with a pyramidal top. Seeds are few and pendant from the apex of the cells (Warrier et al, 1993).

Another species belonging to the genus Acorus is A. gramineus Soland, the roots of which are used in tonic, antiseptics and insecticidal preparations (Chopra et al, 1956).

Agrotechnology: Acorus is a hardy plant found growing from tropical to subtropical climates. It needs a good and well distributed rainfall throughout the year. It needs ample sunlight during the growth period as well as after harvest for drying the rhizomes. It may be cultivated in any good but fairly moist soil. It is usually grown in areas where paddy can be grown. It comes up well in clayey soils and light alluvial soils of river bank. The field is laid out and prepared exactly as for rice, irrigated sufficiently and after ploughing twice, watered heavily and again ploughed in the puddle. Sprouted rhizome pieces are used for planting and pressed into the mud at a depth of about 5cm at a spacing of 30x30cm. The rhizomes are planted in such a way that the plants in the second row comes in between the plants of the first row and not opposite to them. FYM is to be applied at 25t/ha. Fertilisers are applied at 25:50:60 kg N:P2O5:K2O/ha/yr. Whole of FYM and 1/3 of N, P2O5 and K2O are to be added in the field during March - April as a basal dose. The remaining 2/3 of nutrients is to be given in two equal split doses at 4 months and 8 months after planting. The field is to be regularly irrigated. About 5 cm of standing water is to be maintained in the field in the beginning. Later, it is to be increased to 10 cm as the plant grows. The field is to be regularly weeded. About 8 weedings are to be carried out in all. At each weeding the plants are pressed into the soil. The plant is attacked by mealy bugs. Both shoot and root mealy bugs can be controlled by spraying the shoot and drenching the roots of grown up plants with 10 ml Methyl parathion or 15ml Oxydemeton methyl or 20ml Quinalphos in 10 litres of water. The crop is ready for harvest at the end of first year. The field is to be dried partially so that sufficient moisture is left in the soil to facilitate deep digging. The leaves start turning yellow and dry, indicating maturity. The rhizome will be at a depth of 60cm and having about 30-60cm spread. Therefore, harvesting is to be done carefully. The rhizomes are to be cut into 5-7.5cm long pieces and all the fibrous roots are to be removed. Yield of rhizome is about 10t/ha (Farooqi et al, 1991).

Properties and Activity:Rhizomes, roots and leaves yield essential oil. The important constituents of the Indian oil are asarone and its -isomer. Other constituents are and -pinene, myrcene, camphene, p-cymene, camphor and linalool, sesquiterpenic ketones like asarone, calamone, calacone, acolamone, iso-acolamone, acoragermacrone, epishyobunone, shyobunone and iso- shyobunone. Alcohol present is preisocalamendiol. Sesquiterpene hydrocarbons like elemene, elemane and calarene are also present. Tricyclic sesquiterpenes present are caryophyllene, humulene, guaiene, S-guaizulene, arcurcumene, -cadinene, cadinane, calamenene, calacorene, dihydrocalacorene(calamenene), cadalene and selinene. Roots yield acoric acid as a main constituent in addition to choline. Plant also yields a flavone diglycoside- luteolin 6,8-C-diglucoside.

-asarone is the ma jor constituent of essential oil from rhizome (Dandiya et al, 1958,1959; Raquibuddoula, 1967).

Rhizome is insecticidal, pisicidal, spasmolytic, hypothermic, CNS active and analgesic. Essential oil is anticonvulsant. Rhizome is acrid, bitter, thermogenic, aromatic, intellect promoting, emetic, laxative, carminative, stomachic, anthelmintic, emmenagogue, diuretic, alexeteric, expectorant, anodyne, antispasmodic, aphrodisiac, antiinflammatory, sudorific, antipyretic, sialagogue, insecticidal, tranquillizer, sedative, analgesic, antithermic, antiasthmatic, hypotensive, respiratory depressant, aperitive and tonic.... sweet flag

(Linn.) Sprague.

Synonym: T. copticum Link. Carum copticum Benth. ex Hiern.

Family: Umbelliferae; Apiaceae.

Habitat: Cultivated in Madhya Pradesh, Andhra Pradesh, Gujarat, Maharashtra, Uttar Pradesh, Rajasthan and Bihar.

English: Ammi, Lovage, Carum, Ajowan.

Ayurvedic: Yavaani, Yamaani, Yavaanikaa, Yamaanikaa, Dipyaka.

Unani: Nankhwaah, DesiAjawaayin.

Siddha/Tamil: Omam.

Action: Fruits—carminative, antispasmodic, anticholerin, an- tidiarrhoeal, bechic, stimulant.

The Ayurvedic Pharmacopoeia of India recommends the dried fruits in tympanitis, constipation, colic and helminthiasis. Oil—used as an expectorant in emphysema, bronchial and other respiratory ailments.

Used externally in cases of rheumatism. Leafjuice—anthelmintic. Root— carminative, diuretic, febrifuge.

The aqueous extract of the fruit is a popular remedy for diarrhoea in Indian medicine.

The fruit, in addition to protein (17.1), fat (21.8), carbohydrates (24.6) and mineral matter (7.9%), contains sugars, tannins, flavone and sterol. The seeds contain a phenolic glucoside, 2-methyl-3-glucosyloxy-5-isopropyl phenol.

The principal constituents of the Ajowan oil are the phenols, mainly thymol (35-60%) and some carvacrol. (Crystalized thymol is known in the trade as Ajowan-kaa-phuul, Flower- of-Ajowan.)

Thymol is a powerful antiseptic and antifungal. It is an ingredient in deodorant mouth-washes, toothpastes and gargles. The aqueous portion, left after the separation of essential oil, is known as Omum-water and is prescribed in flatulence and gripe, especially in children.

Dosage: Fruit—3-6 g powder. (API, Vol. I.)... trachyspermum ammi