Hist Health Dictionary

Hist: From 1 Different Sources


Histamine

The defense substance responsible for most inflammation. It is synthesized from the amino acid histidine and is secreted by mast cells, basophils, and blood platelets. It stimulates vasodilation, capillary permeability, muscle contraction of the bronchioles, secretions of a number of glands, and attracts eosinophils, the white blood cells that are capable of moderating the inflammation. Mast cell histamine release is what usually causes allergies.... histamine

Histoplasmosis

A mycotic disease caused by the dimorphic fungi Histoplasma capsulatum and H. duboisei. The former primarily affects the lungs and is acquired by inhalation of spores in bat droppings (often in caves) and the latter affects the skin and is restricted to West Africa.... histoplasmosis

Histology

The study of the minute structure of the tissues using special staining processes which are combined with electron and light microscopy. The specialty is sta?ed by medically quali?ed pathologists (histologists) and scienti?cally quali?ed technicians.... histology

Histidine

An amino acid from which HISTAMINE is derived.... histidine

Histiocytoma

See DERMATOFIBROMA.... histiocytoma

Histogram

A graphic representation of the frequency distribution of a variable. Rectangles are drawn in such a way that their bases lie on a linear scale, representing different intervals, and their heights are proportional to the frequencies of the values within each of the intervals.... histogram

Natural History Of Di Sease

The progressive development of a disease that runs its course without treatment. 1. Stage of susceptibility2. Stage of presymptomatic 3. Stage of clinical disease 4. Stage of disability/resolution Necator americanus See hookworm.... natural history of di sease

Histamine-receptor Antagonists

See H-receptor antagonists.... histamine-receptor antagonists

Histiocytosis X

A rare childhood disease in which there is an overgrowth of a type of tissue cell called a histiocyte. The cause is unknown, but histiocytosis X probably results from a disturbance of the immune system. In the mildest form, rapid cell growth occurs in 1 bone only, usually the skull, a clavicle, a rib, or a vertebra, causing swelling and pain. In the most severe, and least common, form, there is a rash and enlargement of the liver, spleen, and lymph nodes.... histiocytosis x

Histocompatibility Antigens

A group of proteins that have a role in the immune system. Certain types of histocompatibility antigens are essential for the immunological function of killer T cells (see lymphocytes). The antigens act as a guide for killer T cells to recognize and kill abnormal or foreign cells.

The main group of histocompatibility antigens is the human leukocyte antigen (HLA) system, which consists of several series of antigens. A person’s tissue type (the particular set of HLAs in the body tissues) is unique, except for identical twins, who have the same set.

HLA analysis has some useful applications. Comparison of HLA types may show that 2 people are related, and it has been used in paternity testing. The HLA system is also used in tissue-typing to help match recipient and donor tissues before transplant surgery. Certain HLA types occur more frequently in people with particular diseases, such as multiple sclerosis, coeliac disease, and ankylosing spondylitis. HLA testing can help to confirm the presence of such diseases and identify people at risk of developing them.... histocompatibility antigens

Histopathology

A branch of histology concerned with the effects of disease on the microscopic structure of tissues.... histopathology

History-taking

The process by which a doctor learns from patients the symptoms of their illnesses and any previous disorders. (See also diagnosis.)... history-taking

Histaminase

n. an enzyme, widely distributed in the body, that is responsible for the inactivation of histamine.... histaminase

Histamine Acid Phosphate

a derivative of *histamine that was formerly used to test for acid secretion in the stomach in conditions involving abnormal gastric acid secretion, such as *Zollinger-Ellison syndrome.... histamine acid phosphate

Histiocyte

n. a fixed *macrophage, i.e. one that is stationary within connective tissue.... histiocyte

Histiocytosis

n. any of a group of diseases in which there are abnormalities in certain large phagocytic cells (*histiocytes) due to (1) abnormal storage of fats, as in *Gaucher’s disease; (2) inflammatory disorders, as in *Langerhans cell histiocytosis, which includes disorders previously called histiocytosis X; or (3) malignant proliferation of histiocytes.... histiocytosis

Histochemistry

n. the study of the identification and distribution of chemical compounds within and between cells, by means of stains, indicators, and light and electron microscopy. —histochemical adj.... histochemistry

Histocompatibility

n. the form of *compatibility that depends upon tissue components, mainly specific glycoprotein antigens in cell membranes. A high degree of histocompatibility is necessary for a tissue graft or organ transplant to be successful. —histocompatible adj.... histocompatibility

Histogenesis

n. the formation of tissues.... histogenesis

Histoid

adj. 1. resembling normal tissue. 2. composed of one type of tissue.... histoid

Histone

n. a simple protein that combines with a nucleic acid to form a *nucleoprotein.... histone

Histoplasma

n. a genus of parasitic yeastlike fungi. The species H. capsulatum causes the respiratory infection *histoplasmosis.... histoplasma

Histoplasmin

n. a preparation of antigenic material from a culture of the fungus Histoplasma capsulatum, used to test for the presence of the disease *histoplasmosis by subcutaneous injection.... histoplasmin

Histotoxic

adj. poisonous to tissues: applied to certain substances and conditions.... histotoxic

Histrionic Personality Disorder

a type of *personality disorder characterized by excessive emotionality and attention-seeking, self-dramatization, inappropriately seductive behaviour, and an excessive need for approval. It affects more women than men. Classified as a specific personality disorder in DSM-IV-TR, in DSM-5 it is treated as a subtype of *narcissistic personality disorder.

HIV (human immunodeficiency virus) a *retrovirus responsible for *AIDS. There are two varieties, HIV-1 and HIV-2; the latter is most common in Africa. See also HTLV.... histrionic personality disorder

Langerhans Cell Histiocytosis

overgrowth of cells of the *reticuloendothelial system. This includes disorders previously called histiocytosis X, including eosinophilic granuloma, Hand–Schüller–Christian disease, and Letterer–Siwe disease. [P. Langerhans (1847–88), German physician and anatomist]... langerhans cell histiocytosis

Major Histocompatibility Complex

see MHC.... major histocompatibility complex



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