Histoplasmosis Health Dictionary

Histoplasmosis: From 4 Different Sources


An infection caused by inhaling the spores of the fungus HISTOPLASMA CAPSULATUM, which is found in soil contaminated with bird or bat droppings.

It occurs in parts of the Americas, the Far East, and Africa.

Health Source: BMA Medical Dictionary
Author: The British Medical Association
A mycotic disease caused by the dimorphic fungi Histoplasma capsulatum and H. duboisei. The former primarily affects the lungs and is acquired by inhalation of spores in bat droppings (often in caves) and the latter affects the skin and is restricted to West Africa.
Health Source: Dictionary of Tropical Medicine
Author: Health Dictionary
A disease due to a yeast-like fungus known as Histoplasma capsulatum. Most cases have been reported from the USA. In infants it is characterised by fever, ANAEMIA, enlargement of the liver and spleen, and involvement of the lungs and gastrointestinal tract. In older children it may resemble pulmonary tuberculosis, whilst in adults it may be con?ned to involvement of the skin.
Health Source: Medical Dictionary
Author: Health Dictionary
n. an infection caused by inhaling spores of the fungus Histoplasma capsulatum. The primary pulmonary form usually produces no symptoms or harmful effects and is recognized retrospectively by X-rays and positive *histoplasmin skin testing. Occasionally, progressive histoplasmosis, which resembles tuberculosis, develops. The fungus may spread via the bloodstream to attack other organs, such as the liver, spleen, lymph nodes, or intestine. Symptomatic disease is treated with intravenous amphotericin. The spores are found in soil contaminated by faeces, especially from chickens and bats. The disease is endemic in the northern and central USA, Argentina, Brazil, Venezuela, and parts of Africa.
Health Source: Oxford | Concise Colour Medical Dictionary
Author: Jonathan Law, Elizabeth Martin

Mycosis

The general term applied to diseases due to the growth of fungi in the body. Among some of the simplest and commonest mycoses are RINGWORM, FAVUS, and thrush (CANDIDA). The MADURA FOOT of India, ACTINOMYCOSIS, and occasional cases of PNEUMONIA and suppurative ear disease are also due to the growth of moulds in the bodily tissues. Other forms of mycosis include ASPERGILLOSIS, candidiasis (see CANDIDA), CRYPTOCOCCOSIS and HISTOPLASMOSIS.... mycosis

Amphotericin B

A drug used to treat fungal infections.

Lozenges are used for candidiasis of the mouth.

Life-threatening infections, such as cryptococcosis and histoplasmosis, are treated by injection.

Adverse effects may occur with injection and include vomiting, fever, headache, and, rarely, seizures.... amphotericin b

Chorionic Villus Sampling

A method of diagnosing genetic abnormalities in a fetus using a small sample of tissue taken from the chorionic villi at edge of the placenta. Because the cells have the same chromosome makeup as those in the fetus, they can be used to detect genetic abnormalities. Chorionic villus sampling (CVS) is usually performed in the first 3 months of pregnancy in women who are at a higher-than-normal risk of having a child with a chromosomal disorder, such as Down’s syndrome, or a genetic disease, such as thalassaemia. Chromosome analysis of the villi cells takes place in the laboratory. CVS slightly increases the risk of miscarriage. choroid A layer of tissue at the back of the eye, behind the retina. The choroid contains many blood vessels that supply nutrients and oxygen to the retinal cells and to surrounding tissues in the eye. choroiditis Inflammation of the choroid. It is often caused by infections such as toxocariasis or toxoplasmosis, more rarely by sarcoidosis, syphilis, and histoplasmosis. It sometimes has no obvious cause. Treatment includes corticosteroid drugs for the inflammation, and antibiotic drugs for any causative infection.... chorionic villus sampling

Choroiditis

Inflammation of the choroid. It is often caused by infections such as toxocariasis or toxoplasmosis, more rarely by sarcoidosis, syphilis, and histoplasmosis. It sometimes has no obvious cause. Treatment includes corticosteroid drugs for the inflammation, and antibiotic drugs for any causative infection.... choroiditis

Fungal Infections

Diseases that are caused by the multiplication and spread of fungi. Some fungi are harmlessly present all the time in areas of the body such as the mouth, skin, intestines, and vagina. However, they are prevented from multiplying by competition from bacteria. Other fungi are dealt with by the body’s immune system.

Fungal infections are therefore more common and serious in people taking long-term antibiotic drugs (which destroy the bacterial competition) and in those whose immune systems are suppressed by immunosuppressant drugs, corticosteroid drugs, or by a disorder such as AIDS. Such serious fungal infections are described as opportunistic infections. Some fungal infections are more common in people with diabetes mellitus.

Fungal infections can be classified into superficial (affecting skin, hair, nails, inside of the mouth, and genital organs); subcutaneous (beneath the skin); and deep (affecting internal organs).

The main superficial infections are tinea (including ringworm and athlete’s foot) and candidiasis (thrush), both of which are common. Subcutaneous infections, which are rare, include sporotrichosis and mycetoma. Deep infections are uncommon but can be serious and include aspergillosis, histoplasmosis, cryptococcosis, and blastomycosis. The fungal spores enter the body by inhalation.

Treatment of fungal infections is with antifungal drugs, either used topically on the infected area or given by mouth for generalized infections.... fungal infections

Histoplasma

n. a genus of parasitic yeastlike fungi. The species H. capsulatum causes the respiratory infection *histoplasmosis.... histoplasma

Histoplasmin

n. a preparation of antigenic material from a culture of the fungus Histoplasma capsulatum, used to test for the presence of the disease *histoplasmosis by subcutaneous injection.... histoplasmin



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