Hyperplasia: From 3 Different Sources
Enlargement of an organ or tissue due to an increase in the number of its cells. The new cells are normal, unlike those of a tumour. Hyperplasia is usually the result of hormonal stimulation. It may occur normally (such as in the enlargement of breast tissue in pregnancy) or it may indicate a disorder. (See also hypertrophy.)
Hyperplasia means an abnormal increase in the number of cells in a tissue.
n. the increased production and growth of normal cells in a tissue or organ without an increase in the size of the cells. The affected part becomes larger but retains its normal form. Hyperplasia can be physiological, as in the breasts during pregnancy, or pathological, as in benign prostatic hyperplasia (see prostate gland). See also endometrial hyperplasia. Compare hypertrophy; neoplasia.
See ADRENOGENITAL SYNDROME and GENETIC DISORDERS.... congenital adrenal hyperplasia
(BPH) A medical term for enlargement of the prostate gland (see prostate, enlarged).... benign prostatic hyperplasia
(BPH) The benign buildup in the prostate of “warts” or epithelial neoplasias that can block or interrupt urination, and which are usually concurrent with moderate prostate enlargement. They cause a dull ache on urination, ejaculation, and/or defecation. The diagnosis is medical, since the same subjective conditions can result from cancer of the prostate. BPH is common in men over fifty and can be the result either of diminished production of complete testosterone or poor pelvic circulation. Alcohol, coffee, speed, and antihistamines can all aggravate the problem.... benign prostatic hypertrophy, or hyperplasia
See hyperplasia, gingival.... gingival hyperplasia
an increase in the thickness of the cells of the *endometrium, usually due to prolonged exposure to unopposed oestrogen, which can be endogenous, as in anovular menstrual cycles; or exogenous, deriving, for example, from *hormone replacement therapy or an oestrogen-secreting tumour. It is classified as simple, complex, or atypical. Endometrial hyperplasia most commonly presents with abnormal uterine bleeding and accounts for 15% cases of postmenopausal bleeding. It may also be asymptomatic, and in some cases regresses spontaneously without ever being detected. The presence of atypical cells may lead to *endometrial cancer. Treatment can include progestogen therapy or surgery (see endometrial ablation); hysterectomy is advised when atypical changes are present.... endometrial hyperplasia
a pathological process involved in *atherosclerosis of arteries and vein grafts, and in *restenosis, that may be in response to angioplasty and stent placement. Damage to the endothelium of the artery exposes the underlying smooth muscle cells in the *media to cytokines, growth factors, and other plasma components in the circulation, which results in loss of their contractile characteristics. These abnormal muscle cells migrate to the *intima, where they proliferate and eventually form a thick layer of tissue (neointima), which occludes the artery.... neointimal hyperplasia
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