A complication of severe HYPERTENSION, this serious but uncommon condition is characterised by neurological symptoms which include transient verbal and visual disturbances, PARAESTHESIA, disorientation, ?ts and sometimes loss of consciousness. It also affects the eyes, causing PAPILLOEDEMA. Haemorrhages may occur in the brain, usually in the area of the BASAL GANGLIA. Neurological symptoms can usually be treated e?ectively by controlling the patient’s hypertension.
A neuropsychiatric syndrome caused by disease of the LIVER, and occurring most often in patients with CIRRHOSIS – see also LIVER, DISEASES OF; it also occurs in acute form in acute failure of liver function. The disorder is believed to be the result of biochemical disturbance of brain function, because the condition is reversible and pathological changes in brain tissue are rarely found. The patient’s intellect, personality, emotions and consciousness are altered but neurological signs may or may not be identi?ed. Apathy, confusion, drowsiness, sometimes CONVULSIONS, speech disturbance and eventually COMA mark the progress of the condition. The principles of treatment are to remove the precipitating causes. These include: URAEMIA; sedative, antidepressant and hypnotic drugs; gastrointestinal bleeding; too much protein in the diet; infection; and trauma (including surgical operations).... hepatic encephalopathy
A disease of the neurological system caused by a PRION. Spongy degeneration of the BRAIN occurs with progressive DEMENTIA. Known examples of the disorder in humans are CREUTZFELDT-JAKOB DISEASE (CJD) and KURU. Among animals, scrapie in sheep and BOVINE SPONGIFORM ENCEPHALOPATHY (BSE) are caused by slow viruses. The latter has occurred as an outbreak in cattle over the past decade or so, probably as a result of cattle being fed processed o?al from infected animals. Some people have developed a form of CJD from eating infected beef.... spongiform encephalopathy
(HIE, birth asphyxia, perinatal asphyxia) brain damage in a newborn infant as a result of the brain receiving inadequate oxygen. HIE may cause seizures and, if severe, death within minutes of oxygen deprivation. If the infant survives there can be significant long-term consequences, such as developmental delay, learning disabilities, or cerebral palsy.... hypoxic-ischaemic encephalopathy