n. a recently discovered neuropeptide that originates in the hypothalamus. Low levels of hypocretin in the cerebrospinal fluid are found in most patients with *narcolepsy and may also be found in patients who have suffered with stroke, brain tumours, head injuries, and infections of the nervous system.
n. an extreme tendency to fall asleep in quiet surroundings or when engaged in monotonous activities. The patient can be woken easily and is immediately alert. It is often associated with *cataplexy, *sleep paralysis, and hypnagogic *hallucinations. One in 2000 individuals may be affected. Narcolepsy is strongly associated with reduced levels of *hypocretin in the cerebrospinal fluid. —narcoleptic adj., n.... narcolepsy