Impotence Health Dictionary

Finasteride is a drug which inhibits the ENZYME that metabolises TESTOSTERONE into the more potent ANDROGEN, dihydrotestosterone. This action results in a reduction of prostate tissue. The drug is used to treat an enlarged PROSTATE GLAND, thus improving urinary ?ow. Its side-effects include reduced LIBIDO, and IMPOTENCE. Finasteride o?ers an alternative to PROSTATECTOMY for some men but a signi?cant minority do not improve. Women of childbearing age should not handle broken or crushed tablets.... finasteride

A colourless liquid, also called ethanol or ethyl-alcohol, produced by the fermentation of carbohydrates by yeast. Medically, alcohol is used as a solvent and an antiseptic; recreationally it is a widely used drug, taken in alcoholic drinks to give a pleasant taste as well as to relax, reduce inhibitions, and increase sociability. Taken to excess, alcohol causes much mental and physical harm – not just to the individual imbibing it, but often to their family, friends, community and work colleagues.

Alcohol depresses the central nervous system and disturbs both mental and physical functioning. Even small doses of alcohol will slow a person’s re?exes and concentration; potentially dangerous effects when, for example, driving or operating machinery. Drunkenness causes slurred speech, muddled thinking, amnesia (memory loss), drowsiness, erectile IMPOTENCE, poor coordination and dulled reactions – thereby making driving or operating machinery especially dangerous. Disinhibition may lead to extreme euphoria, irritability, misery or aggression, depending on the underlying mood at the start of drinking. Severe intoxication may lead to COMA and respiratory failure.

Persistent alcohol misuse leads to physical, mental, social and occupational problems, as well as to a risk of DEPENDENCE (see also ALCOHOL DEPENDENCE). Misuse may follow several patterns: regular but controlled heavy intake, ‘binge’ drinking, and dependence (alcoholism). The ?rst pattern usually leads to mainly physical problems such as gastritis, peptic ulcer, liver disease, heart disease and impotence. The second is most common among young men and usually leads to mainly social and occupational problems – getting into ?ghts, jeopardising personal relationships, overspending on alcohol at weekends, and missing days o? work because of hangovers. The third pattern – alcohol dependence – is the most serious, and can severely disrupt health and social stability.

Many researchers consider alcohol dependence to be an illness that runs in families, with a genetic component which is probably passed on as a vulnerable personality. But it is hard to disentangle genetic, environmental and social factors in such families. In the UK there are estimated to be around a million people suffering from alcohol dependence and a similar number who have di?culty controlling their consumption (together about 1:30 of the population).

Alcohol causes tolerance and both physical and psychological dependence (see DEPENDENCE for de?nitions). Dependent drinkers classically drink early in the morning to relieve overnight withdrawal symptoms. These symptoms include anxiety, restlessness, nausea and vomiting, and tremor. Sudden withdrawal from regular heavy drinking can lead to life-threatening delirium tremens (DTs), with severe tremor, hallucinations (often visual – seeing spiders and monsters, rather than the pink elephants of romantic myth), and CONVULSIONS. This must be treated urgently with sedative drugs, preferably by intravenous drip. Similar symptoms, plus severe INCOORDINATION and double-vision, can occur in WERNICKE’S ENCEPHALOPATHY, a serious neurological condition due to lack of the B vitamin thiamine (whose absorption from the stomach is markedly reduced by alcohol). If not treated urgently with injections of thiamine and other vitamins, this can lead to an irreversible form of brain damage called Korsako?’s psychosis, with severe amnesia. Finally, prolonged alcohol misuse can cause a form of dementia.

In addition to these severe neurological disorders, the wide range of life-threatening problems caused by heavy drinking includes HEPATITIS, liver CIRRHOSIS, pancreatitis (see PANCREAS, DISEASES OF), gastrointestinal haemorrhage, suicide and FETAL ALCOHOL SYNDROME; pregnant women should not drink alcohol as this syndrome may occur with more than a glass of wine or half-pint of beer a day. The social effects of alcohol misuse – such as marital breakdown, family violence and severe debt – can be equally devastating.

Treatment of alcohol-related problems is only moderately successful. First, many of the physical problems are treated in the short term by doctors who fail to spot, or never ask about, heavy drinking. Second, attempts at treating alcohol dependence by detoxi?cation or ‘drying out’ (substituting a tranquillising drug for alcohol and withdrawing it gradually over about a week) are not always followed-up by adequate support at home, so that drinking starts again. Home support by community alcohol teams comprising doctors, nurses, social workers and, when appropriate, probation o?cers is a recent development that may have better results. Many drinkers ?nd the voluntary organisation Alcoholics Anonymous (AA) and its related groups for relatives (Al-Anon) and teenagers (Alateen) helpful because total abstinence from alcohol is encouraged by intensive psychological and social support from fellow ex-drinkers.

Useful contacts are: Alcoholics Anonymous; Al-Anon Family Groups UK and Eire (including Alateen); Alcohol Concern; Alcohol Focus Scotland; and Alcohol and Substance Misuse.

1 standard drink =1 unit

=••• pint of beer

=1 measure of spirits

=1 glass of sherry or vermouth

=1 glass of wine

Limits within which alcohol is believed not to cause long-term health risks:... alcohol

The counselling and treatment of individuals with psychosexual dysfunction (see SEXUAL DYSFUNCTION). Around half of couples experience some type of sexual problem during their relationships, and for most of them the diffculties are psychological. Sexual therapy is usually given to both partners, but sometimes individual counselling is necessary. Couples may sometimes ?nd that group therapy is helpful. Therapy has proved e?ective especially for women with VAGINISMUS (spasm of vaginal muscles), men with PREMATURE EJACULATION or IMPOTENCE, and men and women who fail to achieve ORGASM.... sex therapy

A noncancerous tumour of the pituitary gland that causes overproduction of prolactin. In women, this may result in galactorrhoea, amenorrhoea, or infertility. In men, it may cause impotence and gynaecomastia. In either sex, it may cause headaches, diabetes insipidus, and, if the tumour presses on the optic nerves, loss of the outer visual field. Diagnosis is made from blood tests and CT scanning or MRI of the brain. Treatment may involve removal of the tumour, radiotherapy, or giving the drug bromocriptine.... prolactinoma

A potassium-sparing diuretic drug, which is given to treat heart failure.

Spironolactone may cause numbness, weakness, and nausea.

Less common side effects include diarrhoea, lethargy, impotence, rash, and irregular menstruation.

High doses may cause abnormal breast enlargement in men.... spironolactone

(Ale)

Nutritional Profile Energy value (calories per serving): Low Protein: Moderate Fat: None Saturated fat: None Cholesterol: None Carbohydrates: High Fiber: None Sodium: Low Major vitamin contribution: B vitamins Major mineral contribution: Phosphorus

About the Nutrients in This Food Beer and ale are fermented beverages created by yeasts that convert the sugars in malted barley and grain to ethyl alcohol (a.k.a. “alcohol,” “drink- ing alcohol”).* The USDA /Health and Human Services Dietary Guidelines for Americans defines one drink as 12 ounces of beer, five ounces of wine, or 1.25 ounces of distilled spirits. One 12-ounce glass of beer has 140 calo- ries, 86 of them (61 percent) from alcohol. But the beverage—sometimes nicknamed “liquid bread”—is more than empty calories. Like wine, beer retains small amounts of some nutrients present in the food from which it was made. * Because yeasts cannot digest t he starches in grains, t he grains to be used in mak ing beer and ale are allowed to germinate ( “malt” ). When it is t ime to make t he beer or ale, t he malted grain is soaked in water, forming a mash in which t he starches are split into simple sugars t hat can be digested (fermented) by t he yeasts. If undisturbed, t he fermentat ion will cont inue unt il all t he sugars have been digested, but it can be halted at any t ime simply by raising or lowering t he temperature of t he liquid. Beer sold in bott les or cans is pasteurized to k ill t he yeasts and stop t he fermentat ion. Draft beer is not pasteurized and must be refrigerated unt il tapped so t hat it will not cont inue to ferment in t he container. The longer t he shipping t ime, t he more likely it is t hat draft beer will be exposed to temperature variat ions t hat may affect its qualit y—which is why draft beer almost always tastes best when consumed near t he place where it was brewed. The Nutrients in Beer (12-ounce glass)

Nutrients	Beer	%R DA
Calcium	17 mg	1.7
Magnesium	28.51 mg	7–9*
Phosphorus	41.1 mg	6
Potassium	85.7 mg	(na)
Zinc	0.06 mg	0.5– 0.8*
Thiamin	0.02 mg	1.6 –1.8*
R iboflavin	0.09 mg	7– 8*
Niacin	1.55 mg	10
Vitamin B6	0.17 mg	13
Folate	20.57 mcg	5

  * t he first figure is t he %R DA for a man; t he second, for a woman Source: USDA Nut rient Database: w w w.nal.usda.gov/fnic/cgi-bin /nut _search.pl.

Diets That May Restrict or Exclude This Food Bland diet Gluten-free diet Low-purine (antigout) diet

Buying This Food Look for: A popular brand that sells steadily and will be fresh when you buy it. Avoid: Dusty or warm bottles and cans.

Storing This Food Store beer in a cool place. Beer tastes best when consumed within two months of the day it is made. Since you cannot be certain how long it took to ship the beer to the store or how long it has been sitting on the grocery shelves, buy only as much beer as you plan to use within a week or two. Protect bottled beer and open bottles or cans of beer from direct sunlight, which can change sulfur compounds in beer into isopentyl mercaptan, the smelly chemical that gives stale beer its characteristic unpleasant odor.

When You Are Ready to Serve This Food Serve beer only in absolutely clean glasses or mugs. Even the slightest bit of grease on the side of the glass will kill the foam immediately. Wash beer glasses with detergent, not soap, and let them drain dry rather than drying them with a towel that might carry grease from your hands to the glass. If you like a long-lasting head on your beer, serve the brew in tall, tapering glasses to let the foam spread out and stabilize. For full flavor, serve beer and ales cool but not ice-cold. Very low temperatures immo- bilize the molecules that give beer and ale their flavor and aroma.

What Happens When You Cook This Food When beer is heated (in a stew or as a basting liquid), the alcohol evaporates but the flavor- ing agents remain intact. Alcohol, an acid, reacts with metal ions from an aluminum or iron pot to form dark compounds that discolor the pot or the dish you are cooking in. To prevent this, prepare dishes made with beer in glass or enameled pots.

Medical Uses and/or Benefits Reduced risk of heart attack. Data from the American Cancer Society’s Cancer Prevention Study 1, a 12-year survey of more than 1 million Americans in 25 states, shows that men who take one drink a day have a 21 percent lower risk of heart attack and a 22 percent lower risk of stroke than men who do not drink at all. Women who have up to one drink a day also reduce their risk of heart attack. Numerous later studies have confirmed these findings. Lower risk of stroke. In January 1999, the results of a 677-person study published by researchers at New York Presbyterian Hospital-Columbia University showed that moder- ate alcohol consumption reduces the risk of stroke due to a blood clot in the brain among older people (average age: 70). How the alcohol prevents stroke is still unknown, but it is clear that moderate use of alcohol is a key. Heavy drinkers (those who consume more than seven drinks a day) have a higher risk of stroke. People who once drank heavily, but cut their consumption to moderate levels, can also reduce their risk of stroke. Numerous later studies have confirmed these findings. Lower cholesterol levels. Beverage alcohol decreases the body’s production and storage of low-density lipoproteins (LDLs), the protein and fat particles that carr y cholesterol into your arteries. As a result, people who drink moderately tend to have lower cholesterol levels and higher levels of high density lipoproteins (HDLs), the fat and protein particles that carr y cholesterol out of the body. The USDA /Health and Human Services Dietar y Guidelines for Americans defines moderation as two drinks a day for a man, one drink a day for a woman. Stimulating the appetite. Alcoholic beverages stimulate the production of saliva and the gastric acids that cause the stomach contractions we call hunger pangs. Moderate amounts of alcoholic beverages, which may help stimulate appetite, are often prescribed for geriatric patients, convalescents, and people who do not have ulcers or other chronic gastric problems that might be exacerbated by the alcohol. Dilation of blood vessels. Alcohol dilates the capillaries (the tiny blood vessels just under the skin), and moderate amounts of alcoholic beverages produce a pleasant flush that temporar- ily warms the drinker. But drinking is not an effective way to warm up in cold weather since the warm blood that flows up to the capillaries will cool down on the surface of your skin and make you even colder when it circulates back into the center of your body. Then an alco- hol flush will make you perspire, so that you lose more heat. Excessive amounts of beverage alcohol may depress the mechanism that regulates body temperature.

Adverse Effects Associated with This Food Increased risk of breast cancer. In 2008, scientists at the National Cancer Institute released data from a seven-year survey of more than 100,000 postmenopausal women showing that even moderate drinking (one to two drinks a day) may increase by 32 percent a woman’s risk of developing estrogen-receptor positive (ER+) and progesterone-receptor positive (PR+) breast cancer, tumors whose growth is stimulated by hormones. No such link was found between consuming alcohol and the risk of developing ER-/PR- tumors (not fueled by hor- mones). The finding applies to all types of alcohol: beer, wine, and spirits. Increased risk of oral cancer (cancer of the mouth and throat). Numerous studies confirm the American Cancer Society’s warning that men and women who consume more than two drinks a day are at higher risk of oral cancer than are nondrinkers or people who drink less. Note: The Dietary Guidelines for Americans describes one drink as 12 ounces of beer, five ounces of wine, or 1.5 ounces of distilled spirits. Increased risk of cancer of the colon and rectum. In the mid-1990s, studies at the University of Oklahoma suggested that men who drink more than five beers a day are at increased risk of rectal cancer. Later studies suggested that men and women who are heavy beer or spirits drinkers (but not those who are heavy wine drinkers) have a higher risk of colorectal cancers. Further studies are required to confirm these findings. Fetal alcohol syndrome. Fetal alcohol syndrome is a specific pattern of birth defects—low birth weight, heart defects, facial malformations, and mental retardation—first recognized in a study of babies born to alcoholic women who consumed more than six drinks a day while pregnant. Subsequent research has found a consistent pattern of milder defects in babies born to women who consume three to four drinks a day or five drinks on any one occasion while pregnant. To date, there is no evidence of a consistent pattern of birth defects in babies born to women who consume less than one drink a day while pregnant, but two studies at Columbia University have suggested that as few as two drinks a week while preg- nant may raise a woman’s risk of miscarriage. (“One drink” means 12 ounces of beer, five ounces of wine, or 1.25 ounces of distilled spirits.) Alcoholism. Alcoholism is an addiction disease, the inability to control one’s alcohol consumption. It is a potentially life-threatening condition, with a higher risk of death by accident, suicide, malnutrition, or acute alcohol poisoning, a toxic reaction that kills by para- lyzing body organs, including the heart. Malnutrition. While moderate alcohol consumption stimulates appetite, alcohol abuse depresses it. In addition, an alcoholic may drink instead of eating. When an alcoholic does eat, excess alcohol in his/her body prevents absorption of nutrients and reduces the ability to synthesize new tissue. Hangover. Alcohol is absorbed from the stomach and small intestine and carried by the bloodstream to the liver, where it is oxidized to acetaldehyde by alcohol dehydrogenase (ADH), the enzyme our bodies use to metabolize the alcohol we produce when we digest carbohydrates. The acetaldehyde is converted to acetyl coenzyme A and either eliminated from the body or used in the synthesis of cholesterol, fatty acids, and body tissues. Although individuals vary widely in their capacity to metabolize alcohol, on average, normal healthy adults can metabolize the alcohol in one quart of beer in approximately five to six hours. If they drink more than that, they will have more alcohol than the body’s natural supply of ADH can handle. The unmetabolized alcohol will pile up in the bloodstream, interfering with the liver’s metabolic functions. Since alcohol decreases the reabsorption of water from the kidneys and may inhibit the secretion of an antidiuretic hormone, they will begin to urinate copiously, losing magnesium, calcium, and zinc but retaining more irritating uric acid. The level of lactic acid in the body will increase, making them feel tired and out of sorts; their acid-base balance will be out of kilter; the blood vessels in their heads will swell and throb; and their stomachs, with linings irritated by the alcohol, will ache. The ultimate result is a “hangover” whose symptoms will disappear only when enough time has passed to allow their bodies to marshal the ADH needed to metabolize the extra alcohol in their blood. Changes in body temperature. Alcohol dilates capillaries, tiny blood vessels just under the skin, producing a “flush” that temporarily warms the drinker. But drinking is not an effective way to stay warm in cold weather. Warm blood flowing up from the body core to the surface capillaries is quickly chilled, making you even colder when it circulates back into your organs. In addition, an alcohol flush triggers perspiration, further cooling your skin. Finally, very large amounts of alcohol may actually depress the mechanism that regulates body temperature. Impotence. Excessive drinking decreases libido (sexual desire) and interferes with the ability to achieve or sustain an erection. “Beer belly.” Data from a 1995, 12,000 person study at the University of North Carolina in Chapel Hill show that people who consume at least six beers a week have more rounded abdomens than people who do not drink beer. The question left to be answered is which came first: the tummy or the drinking.

Food/Drug Interactions Acetaminophen (Tylenol, etc.). The FDA recommends that people who regularly have three or more drinks a day consult a doctor before using acetaminophen. The alcohol/acetamino- phen combination may cause liver failure. Disulfiram (Antabuse). Taken with alcohol, disulfiram causes flushing, nausea, low blood pressure, faintness, respiratory problems, and confusion. The severity of the reaction gener- ally depends on how much alcohol you drink, how much disulfiram is in your body, and how long ago you took it. Disulfiram is used to help recovering alcoholics avoid alcohol. (If taken with alcohol, metronidazole [Flagyl], procarbazine [Matulane], quinacrine [Atabrine], chlorpropamide (Diabinase), and some species of mushrooms may produce a mild disulfi- ramlike reaction.) Anticoagulants. Alcohol slows the body’s metabolism of anticoagulants (blood thinners) such as warfarin (Coumadin), intensif ying the effect of the drugs and increasing the risk of side effects such as spontaneous nosebleeds. Antidepressants. Alcohol may increase the sedative effects of antidepressants. Drinking alcohol while you are taking a monoamine oxidase (M AO) inhibitor is especially hazard- ous. M AO inhibitors inactivate naturally occurring enzymes in your body that metabolize tyramine, a substance found in many fermented or aged foods. Tyramine constricts blood vessels and increases blood pressure. If you eat a food containing tyramine while you are taking an M AO inhibitor, you cannot effectively eliminate the tyramine from your body. The result may be a hypertensive crisis. Ordinarily, fermentation of beer and ale does not produce tyramine, but some patients have reported tyramine reactions after drinking some imported beers. Beer and ale are usually prohibited to those using M AO inhibitors. Aspirin, ibuprofen, ketoprofen, naproxen, and nonsteroidal anti-inflammatory drugs. Like alcohol, these analgesics irritate the lining of the stomach and may cause gastric bleeding. Combining the two intensifies the effect. Insulin and oral hypoglycemics. Alcohol lowers blood sugar and interferes with the metabo- lism of oral antidiabetics; the combination may cause severe hypoglycemia. Sedatives and other central nervous system depressants (tranquilizers, sleeping pills, antidepres- sants, sinus and cold remedies, analgesics, and medication for motion sickness). Alcohol inten- sifies sedation and, depending on the dose, may cause drowsiness, respiratory depression, coma, or death.... beer

Diabetes mellitus is a condition characterised by a raised concentration of glucose in the blood due to a de?ciency in the production and/or action of INSULIN, a pancreatic hormone made in special cells called the islet cells of Langerhans.

Insulin-dependent and non-insulindependent diabetes have a varied pathological pattern and are caused by the interaction of several genetic and environmental factors.

Insulin-dependent diabetes mellitus (IDDM) (juvenile-onset diabetes, type 1 diabetes) describes subjects with a severe de?ciency or absence of insulin production. Insulin therapy is essential to prevent KETOSIS – a disturbance of the body’s acid/base balance and an accumulation of ketones in the tissues. The onset is most commonly during childhood, but can occur at any age. Symptoms are acute and weight loss is common.

Non-insulin-dependent diabetes mellitus (NIDDM) (maturity-onset diabetes, type 2 diabetes) may be further sub-divided into obese and non-obese groups. This type usually occurs after the age of 40 years with an insidious onset. Subjects are often overweight and weight loss is uncommon. Ketosis rarely develops. Insulin production is reduced but not absent.

A new hormone has been identi?ed linking obesity to type 2 diabetes. Called resistin – because of its resistance to insulin – it was ?rst found in mice but has since been identi?ed in humans. Researchers in the United States believe that the hormone may, in part, explain how obesity predisposes people to diabetes. Their hypothesis is that a protein in the body’s fat cells triggers insulin resistance around the body. Other research suggests that type 2 diabetes may now be occurring in obese children; this could indicate that children should be eating a more-balanced diet and taking more exercise.

Diabetes associated with other conditions (a) Due to pancreatic disease – for example, chronic pancreatitis (see PANCREAS, DISORDERS OF); (b) secondary to drugs – for example, GLUCOCORTICOIDS (see PANCREAS, DISORDERS OF); (c) excess hormone production

– for example, growth hormone (ACROMEGALY); (d) insulin receptor abnormalities; (e) genetic syndromes (see GENETIC DISORDERS).

Gestational diabetes Diabetes occurring in pregnancy and resolving afterwards.

Aetiology Insulin-dependent diabetes occurs as a result of autoimmune destruction of beta cells within the PANCREAS. Genetic in?uences are important and individuals with certain HLA tissue types (HLA DR3 and HLA DR4) are more at risk; however, the risks associated with the HLA genes are small. If one parent has IDDM, the risk of a child developing IDDM by the age of 25 years is 1·5–2·5 per cent, and the risk of a sibling of an IDDM subject developing diabetes is about 3 per cent.

Non-insulin-dependent diabetes has no HLA association, but the genetic in?uences are much stronger. The risks of developing diabetes vary with di?erent races. Obesity, decreased exercise and ageing increase the risks of disease development. The risk of a sibling of a NIDDM subject developing NIDDM up to the age of 80 years is 30–40 per cent.

Diet Many NIDDM diabetics may be treated with diet alone. For those subjects who are overweight, weight loss is important, although often unsuccessful. A diet high in complex carbohydrate, high in ?bre, low in fat and aiming towards ideal body weight is prescribed. Subjects taking insulin need to eat at regular intervals in relation to their insulin regime and missing meals may result in hypoglycaemia, a lowering of the amount of glucose in the blood, which if untreated can be fatal (see below).

Oral hypoglycaemics are used in the treatment of non-insulin-dependent diabetes in addition to diet, when diet alone fails to control blood-sugar levels. (a) SULPHONYLUREAS act mainly by increasing the production of insulin;

(b) BIGUANIDES, of which only metformin is available, may be used alone or in addition to sulphonylureas. Metformin’s main actions are to lower the production of glucose by the liver and improve its uptake in the peripheral tissues.

Complications The risks of complications increase with duration of disease.

Diabetic hypoglycaemia occurs when amounts of glucose in the blood become low. This may occur in subjects taking sulphonylureas or insulin. Symptoms usually develop when the glucose concentration falls below 2·5 mmol/l. They may, however, occur at higher concentrations in subjects with persistent hyperglycaemia – an excess of glucose – and at lower levels in subjects with persistent hypo-glycaemia. Symptoms include confusion, hunger and sweating, with coma developing if blood-sugar concentrations remain low. Re?ned sugar followed by complex carbohydrate will return the glucose concentration to normal. If the subject is unable to swallow, glucagon may be given intramuscularly or glucose intravenously, followed by oral carbohydrate, once the subject is able to swallow.

Although it has been shown that careful control of the patient’s metabolism prevents late complications in the small blood vessels, the risk of hypoglycaemia is increased and patients need to be well motivated to keep to their dietary and treatment regime. This regime is also very expensive. All risk factors for the patient’s cardiovascular system – not simply controlling hyperglycaemia – may need to be reduced if late complications to the cardiovascular system are to be avoided.

Diabetes is one of the world’s most serious health problems. Recent projections suggest that the disorder will affect nearly 240 million individuals worldwide by 2010 – double its prevalence in 1994. The incidence of insulin-dependent diabetes is rising in young children; they will be liable to develop late complications.

Although there are complications associated with diabetes, many subjects live normal lives and survive to an old age. People with diabetes or their relatives can obtain advice from Diabetes UK (www.diabetes.org.uk).

Increased risks are present of (a) heart disease, (b) peripheral vascular disease, and (c) cerebrovascular disease.

Diabetic eye disease (a) retinopathy, (b) cataract. Regular examination of the fundus enables any abnormalities developing to be detected and treatment given when appropriate to preserve eyesight.

Nephropathy Subjects with diabetes may develop kidney damage which can result in renal failure.

Neuropathy (a) Symmetrical sensory polyneuropathy; damage to the sensory nerves that commonly presents with tingling, numbness of pain in the feet or hands. (b) Asymmetrical motor diabetic neuropathy, presenting as progressive weakness and wasting of the proximal muscles of legs. (c) Mononeuropathy; individual motor or sensory nerves may be affected. (d) Autonomic neuropathy, which affects the autonomic nervous system, has many presentations including IMPOTENCE, diarrhoea or constipation and postural HYPOTENSION.

Skin lesions There are several skin disorders associated with diabetes, including: (a) necrobiosis lipoidica diabeticorum, characterised by one or more yellow atrophic lesions on the legs;

(b) ulcers, which most commonly occur on the feet due to peripheral vascular disease, neuropathy and infection. Foot care is very important.

Diabetic ketoacidosis occurs when there is insu?cient insulin present to prevent KETONE production. This may occur before the diagnosis of IDDM or when insu?cient insulin is being given. The presence of large amounts of ketones in the urine indicates excess ketone production and treatment should be sought immediately. Coma and death may result if the condition is left untreated.

Symptoms Thirst, POLYURIA, GLYCOSURIA, weight loss despite eating, and recurrent infections (e.g. BALANITIS and infections of the VULVA) are the main symptoms.

However, subjects with non-insulindependent diabetes may have the disease for several years without symptoms, and diagnosis is often made incidentally or when presenting with a complication of the disease.

Treatment of diabetes aims to prevent symptoms, restore carbohydrate metabolism to as near normal as possible, and to minimise complications. Concentration of glucose, fructosamine and glycated haemoglobin in the blood are used to give an indication of blood-glucose control.

Insulin-dependent diabetes requires insulin for treatment. Non-insulin-dependent diabetes may be treated with diet, oral HYPOGLYCAEMIC AGENTS or insulin.

Insulin All insulin is injected – mainly by syringe but sometimes by insulin pump – because it is inactivated by gastrointestinal enzymes. There are three main types of insulin preparation: (a) short action (approximately six hours), with rapid onset; (b) intermediate action (approximately 12 hours); (c) long action, with slow onset and lasting for up to 36 hours. Human, porcine and bovine preparations are available. Much of the insulin now used is prepared by genetic engineering techniques from micro-organisms. There are many regimens of insulin treatment involving di?erent combinations of insulin; regimens vary depending on the requirements of the patients, most of whom administer the insulin themselves. Carbohydrate intake, energy expenditure and the presence of infection are important determinants of insulin requirements on a day-to-day basis.

A new treatment for diabetes, pioneered in Canada and entering its preliminary clinical trials in the UK, is the transplantation of islet cells of Langerhans from a healthy person into a patient with the disorder. If the transplantation is successful, the transplanted cells start producing insulin, thus reducing or eliminating the requirement for regular insulin injections. If successful the trials would be a signi?cant advance in the treatment of diabetes.

Scientists in Israel have developed a drug, Dia Pep 277, which stops the body’s immune system from destroying pancratic ? cells as happens in insulin-dependent diabetes. The drug, given by injection, o?ers the possibility of preventing type 1 diabetes in healthy people at genetic risk of developing the disorder, and of checking its progression in affected individuals whose ? cells are already perishing. Trials of the drug are in progress.... diabetes mellitus

(Brandy, gin, rum, tequila, whiskey, vodka)

Nutritional Profile Energy value (calories per serving): Moderate to high Protein: None Fat: None Saturated fat: None Cholesterol: None Carbohydrates: None (except for cordials which contain added sugar) Fiber: None Sodium: Low Major vitamin contribution: None Major mineral contribution: Phosphorus

About the Nutrients in This Food Spirits are the clear liquids produced by distilling the fermented sugars of grains, fruit, or vegetables. The yeasts that metabolize these sugars and convert them into alcohol stop growing when the concentration of alcohol rises above 12–15 percent. In the United States, the proof of an alcoholic beverage is defined as twice its alcohol content by volume: a beverage with 20 percent alcohol by volume is 40 proof. This is high enough for most wines, but not high enough for most whiskies, gins, vodkas, rums, brandies, and tequilas. To reach the concentra- tion of alcohol required in these beverages, the fermented sugars are heated and distilled. Ethyl alcohol (the alcohol in beer, wine, and spirits) boils at a lower temperature than water. When the fermented sugars are heated, the ethyl alcohol escapes from the distillation vat and condenses in tubes leading from the vat to a collection vessel. The clear liquid that collects in this vessel is called distilled spirits or, more technically, grain neutral spirits. Gins, whiskies, cordials, and many vodkas are made with spirits American whiskeys (which include bourbon, rye, and distilled from grains. blended whiskeys) and Canadian, Irish, and Scotch whiskies are all made from spirits aged in wood barrels. They get their flavor from the grains and their color from the barrels. (Some whiskies are also colored with caramel.) Vodka is made from spirits distilled and filtered to remove all flavor. By law, vodkas made in America must be made with spirits distilled from grains. Imported vodkas may be made with spirits distilled either from grains or potatoes and may contain additional flavoring agents such as citric acid or pepper. Aquavit, for example, is essentially vodka flavored with caraway seeds. Gin is a clear spirit flavored with an infusion of juniper berries and other herbs (botanicals). Cordials (also called liqueurs) and schnapps are flavored spirits; most are sweetened with added sugar. Some cordials contain cream. Rum is made with spirits distilled from sugar cane (molasses). Tequila is made with spirits distilled from the blue agave plant. Brandies are made with spirits distilled from fruit. (Arma- gnac and cognac are distilled from fermented grapes, calvados and applejack from fermented apples, kirsch from fermented cherries, slivovitz from fermented plums.) Unless they contain added sugar or cream, spirits have no nutrients other than alcohol. Unlike food, which has to be metabolized before your body can use it for energy, alcohol can be absorbed into the blood-stream directly from the gastrointestinal tract. Ethyl alcohol provides 7 calories per gram.

The Most Nutritious Way to Serve This Food The USDA /Health and Human Services Dietary Guidelines for Americans defines one drink as 12 ounces of beer, five ounces of wine, or 1.25 ounces of distilled spirits, and “moderate drinking” as two drinks a day for a man, one drink a day for a woman.

Diets That May Restrict or Exclude This Food Bland diet Lactose-free diet (cream cordials made with cream or milk) Low-purine (antigout) diet

Buying This Food Look for: Tightly sealed bottles stored out of direct sunlight, whose energy might disrupt the structure of molecules in the beverage and alter its flavor. Choose spirits sold only by licensed dealers. Products sold in these stores are manufac- tured under the strict supervision of the federal government.

Storing This Food Store sealed or opened bottles of spirits in a cool, dark cabinet.

Preparing This Food All spirits except unflavored vodkas contain volatile molecules that give the beverage its characteristic taste and smell. Warming the liquid excites these molecules and intensifies the flavor and aroma, which is the reason we serve brandy in a round glass with a narrower top that captures the aromatic molecules as they rise toward the air when we warm the glass by holding it in our hands. Whiskies, too, though traditionally served with ice in America, will have a more intense flavor and aroma if served at room temperature.

What Happens When You Cook This Food The heat of cooking evaporates the alcohol in spirits but leaves the flavoring intact. Like other alcoholic beverages, spirits should be added to a recipe near the end of the cooking time to preserve the flavor while cooking away any alcohol bite. Alcohol is an acid. If you cook it in an aluminum or iron pot, it will combine with metal ions to form dark compounds that discolor the pot and the food you are cooking. Any recipe made with spirits should be prepared in an enameled, glass, or stainless-steel pot.

Medical Uses and/or Benefits Reduced risk of heart attack. Data from the American Cancer Society’s Cancer Prevention Study 1, a 12-year survey of more than 1 million Americans in 25 states, shows that men who take one drink a day have a 21 percent lower risk of heart attack and a 22 percent lower risk of stroke than men who do not drink at all. Women who have up to one drink a day also reduce their risk of heart attack. Numerous later studies have confirmed these findings. Lower cholesterol levels. Beverage alcohol decreases the body’s production and storage of low density lipoproteins (LDLs), the protein and fat particles that carry cholesterol into your arteries. As a result, people who drink moderately tend to have lower cholesterol levels and higher levels of high density lipoproteins (HDLs), the fat and protein particles that carry cholesterol out of the body. Numerous later studies have confirmed these findings. Lower risk of stroke. In January 1999, the results of a 677-person study published by researchers at New York Presbyterian Hospital-Columbia University showed that moderate alcohol consumption reduces the risk of stroke due to a blood clot in the brain among older people (average age: 70). How alcohol prevents stroke is still unknown, but it is clear that moderate use is a key. Heavy drinkers (those who consume more than seven drinks a day) have a higher risk of stroke. People who once drank heavily, but cut their consumption to moderate levels, reduce their risk of stroke. Stimulating the appetite. Alcoholic beverages stimulate the production of saliva and the gastric acids that cause the stomach contractions we call hunger pangs. Moderate amounts of alcoholic beverages, which may help stimulate appetite, are often prescribed for geriatric patients, convalescents, and people who do not have ulcers or other chronic gastric problems that might be exacerbated by the alcohol. Dilation of blood vessels. Alcoholic beverages dilate the tiny blood vessels just under the skin, bringing blood up to the surface. That’s why moderate amounts of alcoholic beverages (0.2–1 gram per kilogram of body weight, or two ounces of whiskey for a 150-pound adult) temporarily warm the drinker. But the warm blood that flows up to the surface of the skin will cool down there, making you even colder when it circulates back into the center of your body. Then an alcohol flush will make you perspire, so you lose more heat. Excessive amounts of beverage alcohol may depress the mechanism that regulates body temperature.

Adverse Effects Associated with This Food Alcoholism. Alcoholism is an addiction disease, the inability to control one’s alcohol consumption. It is a potentially life-threatening condition, with a higher risk of death by accident, suicide, malnutrition, or acute alcohol poisoning, a toxic reaction that kills by para- lyzing body organs, including the heart. Fetal alcohol syndrome. Fetal alcohol syndrome is a specific pattern of birth defects—low birth weight, heart defects, facial malformations, learning disabilities, and mental retarda- tion—first recognized in a study of babies born to alcoholic women who consumed more than six drinks a day while pregnant. Subsequent research has found a consistent pattern of milder defects in babies born to women who drink three to four drinks a day or five drinks on any one occasion while pregnant. To date there is no evidence of a consistent pattern of birth defects in babies born to women who consume less than one drink a day while preg- nant, but two studies at Columbia University have suggested that as few as two drinks a week while pregnant may raise a woman’s risk of miscarriage. (One drink is 12 ounces of beer, five ounces of wine, or 1.25 ounces of distilled spirits.) Increased risk of breast cancer. In 2008, scientists at the National Cancer Institute released data from a seven-year survey of more than 100,000 postmenopausal women showing that even moderate drinking (one to two drinks a day) may increase by 32 percent a woman’s risk of developing estrogen-receptor positive (ER+) and progesterone-receptor positive (PR+) breast cancer, tumors whose growth is stimulated by hormones. No such link was found between consuming alcohol and the risk of developing ER-/PR- tumors (not fueled by hor- mones). The finding applies to all types of alcohol: beer, wine, and distilled spirits. Increased risk of oral cancer (cancer of the mouth and throat). Numerous studies confirm the A merican Cancer Societ y’s warn ing that men and women who consume more than t wo drinks a day are at higher risk of oral cancer than are nondrinkers or people who drink less. Increased risk of cancer of the colon and rectum. In the mid-1990s, studies at the University of Oklahoma suggested that men who drink more than five beers a day are at increased risk of rectal cancer. Later studies suggested that men and women who are heavy beer or spirits drinkers (but not those who are heavy wine drinkers) have a higher risk of colorectal cancers. Further studies are required to confirm these findings. Malnutrition. While moderate alcohol consumption stimulates appetite, alcohol abuses depresses it. In addition, an alcoholic may drink instead of eating. When an alcoholic does eat, excess alcohol in his/her body prevents absorption of nutrients and reduces the ability to synthesize new tissue. Hangover. Alcohol is absorbed from the stomach and small intestine and carried by the bloodstream to the liver, where it is oxidized to acetaldehyde by alcohol dehydrogenase (ADH), the enzyme our bodies use every day to metabolize the alcohol we produce when we digest carbohydrates. The acetaldehyde is converted to acetyl coenzyme A and either eliminated from the body or used in the synthesis of cholesterol, fatty acids, and body tis- sues. Although individuals vary widely in their capacity to metabolize alcohol, an adult of average size can metabolize the alcohol in four ounces (120 ml) whiskey in approximately five to six hours. If he or she drinks more than that, the amount of alcohol in the body will exceed the available supply of ADH. The surplus, unmetabolized alcohol will pile up in the bloodstream, interfering with the liver’s metabolic functions. Since alcohol decreases the reabsorption of water from the kidneys and may inhibit the secretion of an antidiuretic hormone, the drinker will begin to urinate copiously, losing magnesium, calcium, and zinc but retaining uric acid, which is irritating. The level of lactic acid in the body will increase, making him or her feel tired and out of sorts; the acid-base balance will be out of kilter; the blood vessels in the head will swell and throb; and the stomach, its lining irritated by the alcohol, will ache. The ultimate result is a hangover whose symptoms will disappear only when enough time has passed to allow the body to marshal the ADH needed to metabolize the extra alcohol in the person’s blood. Changes in body temperature. Alcohol dilates capillaries, tiny blood vessels just under the skin, producing a “flush” that temporarily warms the drinker. But drinking is not an effective way to stay warm in cold weather. Warm blood flowing up from the body core to the surface capillaries is quickly chilled, making you even colder when it circulates back into your organs. In addition, an alcohol flush triggers perspiration, further cooling your skin. Finally, very large amounts of alcohol may actually depress the mechanism that regulates body temperature. Impotence. Excessive drinking decreases libido (sexual desire) and interferes with the ability to achieve or sustain an erection. Migraine headache. Some alcoholic beverages contain chemicals that inhibit PST, an enzyme that breaks down certain alcohols in spirits so that they can be eliminated from the body. If they are not broken down by PST, these alcohols will build up in the bloodstream and may trigger a migraine headache. Gin and vodka appear to be the distilled spirits least likely to trigger headaches, brandy the most likely.

Food/Drug Interactions Acetaminophen (Tylenol, etc.). FDA recommends that people who regularly have three or more drinks a day consult a doctor before using acetaminophen. The alcohol/acetaminophen combination may cause liver failure. Anti-alcohol abuse drugs (disulfiram [Antabuse]). Taken concurrently with alcohol, the anti- alcoholism drug disulfiram can cause flushing, nausea, a drop in blood pressure, breathing difficulty, and confusion. The severity of the symptoms, which may var y among individu- als, generally depends on the amount of alcohol consumed and the amount of disulfiram in the body. Anticoagulants. Alcohol slows the body’s metabolism of anticoagulants (blood thinners), intensif ying the effect of the drugs and increasing the risk of side effects such as spontane- ous nosebleeds. Antidepressants. Alcohol may strengthen the sedative effects of antidepressants. Aspirin, ibuprofen, ketoprofen, naproxen and nonsteroidal anti-inflammatory drugs. Like alco- hol, these analgesics irritate the lining of the stomach and may cause gastric bleeding. Com- bining the two intensifies the effect. Insulin and oral hypoglycemics. Alcohol lowers blood sugar and interferes with the metabo- lism of oral antidiabetics; the combination may cause severe hypoglycemia. Sedatives and other central nervous system depressants (tranquilizers, sleeping pills, antide- pressants, sinus and cold remedies, analgesics, and medication for motion sickness). Alcohol intensifies the sedative effects of these medications and, depending on the dose, may cause drowsiness, sedation, respiratory depression, coma, or death. MAO inhibitors. Monoamine oxidase (M AO) inhibitors are drugs used as antidepressants or antihypertensives. They inhibit the action of natural enzymes that break down tyramine, a substance formed naturally when proteins are metabolized. Tyramine is a pressor amine, a chemical that constricts blood vessel and raises blood pressure. If you eat a food that contains tyramine while you are taking an M AO inhibitor, the pressor amine cannot be eliminated from your body and the result may be a hypertensive crisis (sustained elevated blood pressure). Brandy, a distilled spirit made from wine (which is fermented) contains tyramine. All other distilled spirits may be excluded from your diet when you are taking an M AO inhibitor because the spirits and the drug, which are both sedatives, may be hazard- ous in combination.... distilled spirits

Use of the SEMEN of an anonymous donor to produce fertilisation in cases of INFERTILITY where the male partner has OLIGOSPERMIA or IMPOTENCE. The donor is chosen for ethnic and physiognomic similarity to the male partner and is screened for transmissible diseases

(e.g. HIV, syphilis, hepatitis, gonorrhoea, and genetic disorders). Insemination is performed at the time of ovulation by introducing the semen into the upper vagina. Semen may be fresh or have been stored frozen in liquid nitrogen. (See ARTIFICIAL INSEMINATION.)... donor insemination

The rigid state of the PENIS when it responds to sexual stimulus. An erection is necessary for e?ective penetration of the VAGINA. As a result of sexual arousal, the three cylinders of erectile tissue in the penis become engorged with blood, lengthening, raising and hardening the penis. Muscles surrounding the blood vessels contract and retain the blood in the penis. Erections also occur during sleep and in young boys. Inability to have or maintain an erection is one cause of IMPOTENCE (see also SILDENAFIL CITRATE).... erection

These widely used drugs include a range of different preparations which relieve DEPRESSION. All the antidepressants available at the time of writing are more or less equally e?ective. In studies where patients agree to take either antidepressants or identical dummy PLACEBO pills (without knowing which), at least two-thirds of those who receive antidepressants feel much better within three months, while fewer than one-third of those on placebos recover naturally in the same period. In general these drugs are useful for severe and moderate depression including postnatal illness; they are not e?ective in milder forms of depression although they may be tried for a short time if other therapies have failed.

The most widely prescribed type of antidepressants are the tricyclics, so-called because their molecular structure includes three rings. The other commonly used types are named after the actions they have on chemicals in the brain: the SELECTIVE SEROTONIN-REUPTAKE INHIBITORS (SSRIS) and the MONOAMINE OXIDASE INHIBITORS (MAOIS) – see also below. All types of antidepressant work in similar ways. Tricyclic antidepressants have cured depression in millions of people, but they can cause unpleasant side-effects, particularly in the ?rst couple of weeks. These include SEDATION, dry mouth, excessive sweating, CONSTIPATION, urinary problems, and impotence (inability to get an erection). Up to half of all people prescribed tricyclic drugs cannot tolerate the side-effects and stop treatment before their depression is properly treated. More seriously, tricyclics can upset the rhythm of the heart in susceptible people and should never be given in the presence of heart disease.

The SSRIs are newer, coming into wide use in the late 1980s. They increase the levels in the brain of the chemical messenger SEROTONIN, which is thought to be depleted in depression. Indeed, the SSRIs are as e?ective as tricyclics and, although they can cause nausea and excessive sweating at ?rst, they generally have fewer side-effects. Their main disadvantage, however, is that they cost much more than the most commonly used tricyclic, amitriptyline. On the other hand, they are more acceptable to many patients and they cause fewer drop-outs from treatment – up to a quarter rather than a half. The money saved by completed, successful treatment may outweigh the prescribing costs. SSRIs have been reported as associated with an increased risk of suicide.

Another group of antidepressants, the MAOIs, have been in use since the late 1950s.

They are stimulants, rather than sedatives, and are particularly helpful for people who are physically and mentally slowed by depression. They work well but have one big disadvantage – a dangerous interaction with certain foods and other drugs, causing a sudden and very dangerous increase in blood pressure. People taking them must carry an information card explaining the risk and listing the things that they should avoid. Because of this risk, MAOIs are not used much now, except when other treatments have failed. A new MAOI, moclobemide, which is less likely to interact and so cause high blood pressure, is now available.

LITHIUM CARBONATE is a powerful antidepressant used for intractable depression. It should be used under specialist supervision as the gap between an e?ective dose and a toxic one is narrow.

St John’s Wort is a popular herbal remedy which may be e?ective, but which is handicapped by di?erences of strength between di?erent preparations or batches. It can interact with a number of conventional drugs and so needs to be used cautiously and with advice.

In general, antidepressants work by restoring the balance of chemicals in the brain. Improved sleep and reduced anxiety are usually the ?rst signs of improvement, particularly among people taking the more sedative tricyclic drugs. Improvement in other symptoms follow, with the mood starting to lift after about two weeks of treatment. Most people feel well by three months, although a few residual symptoms, such as slowness in the mornings, may take longer to clear up. People taking antidepressants usually want to stop them as soon as they feel better; however, the risk of relapse is high for up to a year and most doctors recommend continuing the drugs for around 4–6 months after recovery, with gradual reduction of the dose after that.

Withdrawal reactions may occur including nausea, vomiting, headache, giddiness, panic or anxiety and restlessness. The drugs should be withdrawn gradually over about a month or longer (up to six months in those who have been on maintenance treatment).

A wide range of antidepressant drugs is described in the British National Formulary. Examples include:

Tricyclics: amitryptyline, imipramine, doxepin.

MAOIs: phenelzine, isocarboxazid.

SSRIs: citalopram, ?uoxetine, paraxtene. (Antidepressant drugs not in these three

groups include ?upenthixol, mertazapine and venlafaxine.)... antidepressant drugs

Goat weed helps enhance both blood testosterone and sperm production in animals. In human men, this herb is known to promote both sperm production and the male sex drive. It also helps in some cases of impotence. In women, this herb helps ease fatigue and postmenopausal hypertension.... goat weed

(Ugli fruit)

Nutritional Profile Energy value (calories per serving): Low Protein: Low Fat: Low Saturated fat: Low Cholesterol: None Carbohydrates: High Fiber: Moderate Sodium: Low Major vitamin contribution: Vitamin A, vitamin C Major mineral contribution: Potassium

About the Nutrients in This Food Grapefruit and ugli fruit (a cross between the grapefruit and the tangerine) have moderate amounts of dietary fiber and, like all citrus fruits, are most prized for their vitamin C. Pink or red grapefruits have moderate amounts of vitamin A. One-half medium (four-inch diameter) pink grapefruit has 1.4 g dietary fiber, 1,187 IU vitamin A (51 percent of the R DA for a woman, 40 percent of the R DA for a man), and 44 mg vitamin C (59 percent of the R DA for a woman, 49 percent of the R DA for a man). One half medium (3.75-inch diameter) white grapefruit has 1.3 g dietary fiber, 39 IU vitamin A (2 percent of the R DA for a woman, 1 percent of the R DA for a man), and 39 mg vitamin C (52 percent of the R DA for a woman, 43 percent of the R DA for a man). Pink and red grapefruits also contain lycopene, a red carotenoid (plant pigment), a strong antioxidant that appears to lower the risk of cancer of the prostate. The richest source of lycopene is cooked tom atoes.

The Most Nutritious Way to Serve This Food Fresh fruit or fresh-squeezed juice.

Buying This Food Look for: Firm fruit that is heavy for its size, which means that it will be juicy. The skin should be thin, smooth, and fine-grained. Most grapefruit have yellow skin that, depending on the variety, may be tinged with red or green. In fact, a slight greenish tint may mean that the grapefruit is high in sugar. Ugli fruit, which looks like misshapen, splotched grapefruit, is yellow with green patches and bumpy skin. Avoid: Grapefruit or ugli fruit with puff y skin or those that feel light for their size; the flesh inside is probably dry and juiceless.

Storing This Food Store grapefruit either at room temperature (for a few days) or in the refrigerator. Refrigerate grapefruit juice in a tightly closed glass bottle with very little air space at the top. As you use up the juice, transfer it to a smaller bottle, again with very little air space at the top. The aim is to prevent the juice from coming into contact with oxygen, which destroys vitamin C. (Most plastic juice bottles are oxygen-permeable.) Properly stored and protected from oxygen, fresh grapefruit juice can hold its vitamin C for several weeks.

Preparing This Food Grapefruit are most flavorful at room temperature, which liberates the aromatic molecules that give them their characteristic scent and taste. Before cutting into the grapefruit, rinse it under cool running water to flush debris off the peel. To section grapefruit, cut a slice from the top, then cut off the peel in strips—starting at the top and going down—or peel it in a spiral fashion. You can remove the bitter white membrane, but some of the vitamin C will go with it. Finally, slice the sections apart. Or you can simply cut the grapefruit in half and scoop out the sections with a curved, serrated grapefruit knife.

What Happens When You Cook This Food Broiling a half grapefruit or poaching grapefruit sections reduces the fruit’s supply of vitamin C, which is heat-sensitive.

How Other Kinds of Processing Affect This Food Commercially prepared juices. How well a commercially prepared juice retains its vitamin C depends on how it is prepared, stored, and packaged. Commercial flash-freezing preserves as much as 95 percent of the vitamin C in fresh grapefruit juices. Canned juice stored in the refrigerator may lose only 2 percent of its vitamin C in three months. Prepared, pasteurized “fresh” juices lose vitamin C because they are sold in plastic bottles or waxed-paper cartons that let oxygen in. Commercially prepared juices are pasteurized to stop the natural enzyme action that would otherwise turn sugars to alcohols. Pasteurization also protects juices from potentially harmful bacterial and mold contamination. Following several deaths attributed to unpas- teurized apple juices containing E. coli O157:H7, the FDA ruled that all fruit and vegetable juices must carry a warning label telling you whether the juice has been pasteurized. Around the year 2000, all juices must be processed to remove or inactivate harmful bacteria.

Medical Uses and/or Benefits Antiscorbutic. All citrus fruits are superb sources of vitamin C, the vitamin that prevents or cures scurvy, the vitamin C-deficiency disease. Increased absorption of supplemental or dietary iron. If you eat foods rich in vitamin C along with iron supplements or foods rich in iron, the vitamin C will enhance your body’s ability to absorb the iron. Wound healing. Your body needs vitamin C in order to convert the amino acid proline into hydroxyproline, an essential ingredient in collagen, the protein needed to form skin, ten- dons, and bones. As a result people with scurvy do not heal quickly, a condition that can be remedied with vitamin C, which cures the scurvy and speeds healing. Whether taking extra vitamin C speeds healing in healthy people remains to be proved. Possible inhibition of virus that causes chronic hepatitis C infection. In Januar y 2008, research- ers at Massachusetts General Hospital Center for Engineering in Medicine (Boston) published a report in the medical journal Hepatology detailing the effect of naringenin, a compound in grapefruit, on the behavior of hepatitis viruses in liver cells. In laborator y studies, naringenin appeared to inhibit the ability of the virus to multiply and/or pass out from the liver cells. To date, there are no studies detailing the effect of naringenin in human beings with hepatitis C.

Adverse Effects Associated with This Food Contact dermatitis. The essential oils in the peel of citrus fruits may cause skin irritation in sensitive people.

Food/Drug Interactions Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, naproxen and others. Taking aspirin or NSAIDs with acidic foods such as grapefruit may intensif y the drug’s ability to irritate your stomach and cause gastric bleeding. Antihistamines, anticoagulants, benzodiazepines (tranquilizers or sleep medications), calcium channel blockers (blood pressure medication), cyclosporine (immunosuppressant drug used in organ transplants), theophylline (asthma drug). Drinking grapefruit juice with a wide variety of drugs ranging from antihistamines to blood pressure medication appears to reduce the amount of the drug your body metabolizes and eliminates. The “grapefruit effect” was first identified among people taking the antihypertensive drugs felodipine (Plendil) and nifedip- ine (Adalat, Procardia). It is not yet known for certain exactly what the active substance in the juice is. One possibility, however, is bergamottin, a naturally occurring chemical in grapefruit juice known to inactivate cytochrome P450 3A4, a digestive enzyme needed to convert many drugs to water-soluble substances you can flush out of your body. Without an effective supply of cytochrome P450 3A4, the amount of a drug circulating in your body may rise to dangerous levels. Reported side effects include lower blood pressure, increased heart rate, headache, flushing, and lightheadedness. Some Drugs Known to Interact with Grapefruit Juice* Drug Class  Generic (Brand name) Antianxiety drug  Diazepam ( Valium) Antiarrhythmics  Amiodarone (Cordarone) Blood-pressure drugs  Felodipine (Plendil), nicardipine (Cardene), nimodipine (Nimotop), nisoldipine (Sular), verapamil ( Verelan) Cholesterol-lowering drugs  Atorvastatin (Lipitor), lovastatin (Mevacor), simvastatin (Zocor), simvastatin/ezetimibe ( Vytorin) Immune Suppressants  Cyclosporine (Neoral), tacrolimus (Prograf ) Impotence Drug  Sildenafil ( Viagra) Pain Medication Methadone (Dolophine, Methadose) * This list may grow as new research appears.... grapefruit

Holostemma ada-kodien

Asclepiadaceae

San: Jivanti;

Hin: Chirvel, Charivel;

Mal: Atapathiyan, Atapotiyan, Atakotiyan;

Tam: Palaikkirai;

Tel: Palagurugu; Mar: Dudurli, Shidodi;

Guj: Kharner, Khiravel

Importance: Holostemma is a twining shrub with large flowers. The roots of Holostemma are useful in ophthalmopathy, orchitis, cough, burning sensation, stomachalgia, constipation, fever and tridoshas. The leaves, flowers and fruits are eaten as vegetable. The root is also used in spermatorrhoea. It is used in preparations of Vidaryadiganam, Dhanwandharam thaila, Manasamithravatakam, Balarishta and Anuthaila. It is also useful in eye diseases and it imparts resistance to diseases.

Distribution: The plant occurs in tropical countries. In India, it is found in Himalayas, Dehradun, Konkan, Bombay, Deccan, Karnataka, Kerala and Tamilnadu. It grows over hedges and in open forests especially on the lower slopes of the hills. It is also distributed in Sri Lanka, Burma and W. China.

Botany: Holostemma ada-kodien Schult. syn. Holostemma annulare (Roxb.) K. Schum.

Holostemma rheedii Wall. belongs to the family Asclepiadaceae. It is a laticiferous twining shrub with large conspicuous flowers. Leaves are simple, opposite and cordate. Flowers are purple, arranged in axillary umbellate cymes. Fruits are thick follicles, 9 cm long, cylindrical and bluntly pointed. The roots are long upto 1 m or more, irregularly twisted, thick and cylindrical. When dry it is yellowish brown to brown black in colour with nearly smooth surface bearing white scars and small depressions. A mature root is about 1-2 cm thick when extracted for use (Warrier et al, 1995).

Agrotechnology: Holostemma prefers a tropical climate. The plant is propagated vegetatively by stem cuttings, but mainly by seeds. The seeds are collected from the plant in November-December before being dispersed. Seeds are cleaned, dried and stored for sowing. The stored seeds after soaking in water for 4-5 hours are sown in the seedbeds. About one month old seedlings are then planted in polybags of size 14x10cm which are filled with soil, sand and dried cowdung in 1:1:1 ratio, respectively. Polybags should be kept in shade and irrigated. About 1-1.5 month old seedlings are ready for transplanting. Pits of 30cm cube size are taken at 1-1.2m distance and filled with 10kg dried cowdung and sand. This is covered with surface soil and formed into a mound. Seedlings are transplanted on to the mounds from the polybags carefully. Regular irrigation is to be given till flowering. To aid in trailing, staking is given one month after planting. Flowering and fruiting occurs in November-December. Harvesting can be done at the end of second year when the vines start drying up. Harvesting is done by digging up the tubers. The tubers are cut into pieces of 10cm length and dried in sun before sale (Prasad et al, 1997).

Properties and activity: Holostemma tubers give -amyrin, lupeol and -sitosterol. Alanine, aspartic acid, glycine, serine, threonine and valine were detected chromatographically (Hussain et al, 1992). The root is antidiabetic, antigonorrhoeic, bechic, alterative, tonic, lactative, ophthalmic, emollient, stimulant, aphrodisiac, expectorant and galactagogue.

BLACH MUSALE Curculigo orchioides Amaryllidaceae

San: Musali;

Hin: Kalimusali, Mushali;

Ben: Talamuli;

Mal: Nilappana;

Guj: Musalikand

Tam: Nilapanai;

Tel: Nelatadi Kelangu;

Kan: Neladali

Importance: Musali is a small, geophilous herb, the tuberous rootstock of which is used as a rejuvenating and aphrodisiac drug. It cures morbid vata and pitta, improves complexion and is useful in general debility, deafness, cough, asthma, piles, skin diseases, impotence, jaundice, urinary disorders, leucorrhoea and menorrhagia (Nadkarni, 1954; Aiyer and Kolammal, 1963; Mooss, 1978). Rootstock is the officinal part and it enters into the Ayurvedic formulations like Vidaryadighrta, Vidaryadi lehya, Marmagulika, Musalyadi churna etc. The Pharmacognosy of C. orchioides has been discussed by Aiyer, Kolamma l (1963), Raghunathan, and Mitra (1982). A bibliographical study on C. orchioides has been done by Pandey et al (1983).

Distribution: The plant is found in all districts of India from near sea level to 2300m altitude, especially in rock crevices and laterite soil. It has been recorded to occur in the sub tropical Himalayas from Kumaon eastwards ascending to 1800m, the Khasia hills, Bengal, Asssam, Konkan, Kanara, the western peninsula and Madras extending south as far as a Cape Comerin. It is also distributed in Sri Lanka, Japan, Malaysia and Australia.

Botany: Curculigo orchioides Gaertn. syn. C. malabarica Wight, C. brevifolia Dryand, Hypoxis dulcis Stand belongs to the family Amaryllidaceae. Musali is a small herbaceous plant with cylindrical rootstock. Leaves are simple, sessile, crowded on the short stem with sheathing leaf bases. Flowers are bright yellow. Seeds are black, deeply grooved in wavy lines.

A detailed description of the plant is as follows (Victoria, 1998). Rootstock is straight, cylindrical, tuberous, 5-22cm long, 0.5-0.8 cm thick, brownish surfaces marked with closely spaced prominent transverse wrinkles in the upper or basal half. It bears a few stout lateral roots of 5 or more cm long. Lateral roots are dull white in colour and spongy externally. The fresh cut surfaces of the rootstock has a starch white colour and mucilaginous. A few fibrous roots also occur. Leaves are sessile or short petiolate with sheathing bases, 15-45x1.2-2.5 cm size, linear or linear lanceolate, membranous, glabrouus or sparsely sofly hairy and plicate in bud. The leaf tips when contacts the soil, develops roots and produce adventitious buds. Inflorescence is axillary, scapose racemose, the scape very short and hidden among the bases of leaves underground, clavte, flattened with the pedicels, bracts and the ovary concealed in the leaf sheaths. The lower big flowers on the scape are mostly bisexual and the upper small ones staminate. Flowers are epigynous bright yellow, bisexual or unisxual with lanceolate, memb ranous bract.. Perianth gamophyllous, rotate & six lobed, locate at the top of a slender sterile long extension of the ovary by means of which the perianth is exposed above the ground. Perianth lobes similar, elliptic oblong 1.2-1.6 cm long, 0.2-0.3 cm broad, outer lobes hairy on the back, inner ones sparsely hairy along nerves. Stamens 6 in number, filamentous filiform, short 2mm long, adnate to the base of the perianth lobes, Anthers linear or linear lanceolate, basifixed and sagittate,.Ovary inferior, hidden among the leaves usually below the ground, tricarpellary syncarpous, lanceolate and trilocular with a fairly long slender beak or extension -the stipe. Ovules many in each cell attached by a distinct long funicle. Style short columnar, 2mm with a 3 lobed stigma. Lobes elongate, erect and appressed. Fruit is a capsule about 1.5-2cm long, 8mm broad, oblong, glabrescent with a slender beak and spongy septa. Seeds 1-many, oblong, black, shiny with crustaceous testa grooved deeply in wavy lines.

Properties and activity: Rao and Beri (1951) have identified glucose, mannose, xylose and glucuronic acid from the rootstock of C. orchioides. The rootstock is also reported to contain glycoside, polysaccharides (hemicellulose and other polysaccharides), starch, resin, tannin, mucilage, fat and calcium oxalate. The hexane extract contains an alkaloid-lycorine, sterols including -sitosterols and sapogenin identified as yuccagenin (Rao et al, 1978). The flavone glycoside from the rootstock has been identified as 5,7- dimethoxy glucopyranoside (Yadav et al, 1974; Sharma et al 1975). Mehta et al (1980) have isolated a number of fatty acids from C. orchioides root oil by GLC techniques. They are palmitic, oleic, linolenic linoleic, arachidic and behenic acid. Kubo et al (1983) isolated a new phenolic glycoside namely, curculigoside from the rhizomes and its structure has been elucidated as 5- hydroxy-2-0- -d-glucopyranosyl benzl 1,2,6-dimethoxy benzoate. Yamasaki et al (1994) developed HPLC method for estimating the curculigoside content in curculigo rhizome.

Two new aliphatic hydroxy ketone 27-hydroxy tricontan-6-one (M. P. 84-85o C) and 23- hydroxy tricontan-2-one (M. P. 109-110 o C) were isolated from the rhizome by Misra et al (1984). They also isolated 21-hydroxy tetracontan-20-one and 4-methyl heptade canoic acid from the root stock. Porwal et al (1988) have isolated and identified three new compounds from the rhizome as N- acetyl-N-hydroxy-2-carbamic acid methyl ester, 3-acetyl-5-carbomethoxy-2H-3,4,5,6-tetrahydro-1,2,3,5,6-oxatetrazine and N, N, N’, N’-tetra methyl succinamide. The rhizomes of C. orchioides yielded a new phenolic glycoside corchioside a, characterised as orcinol-3- -D-xylopyranosyl- (1 6)- -D-glucopyranoside and hentriacontanol (Garg et al, 1989).

A new aliphatic compound has been isolated from the rhizomes and characterised as 25- dihydroxy-33-methyl pentatricontan-one (Mehta et al, 1990). Misra et al (1990) isolated a new natural triterpene alcohol-Curculigol charactrised as 24-methy cycloart-7-en-3-beta-20-diol. A novel pentacyclic triterpene has been isolated from the rhizomes of C.orchioides and characterised as 31- methyl-3-oxo-20-ursen-28-oic acid (Metha and Gawarikar,1991). Xu and Xu (1992) and Xu et al (1992 a, b) have isolated 13 cycloartane type. Triterpene glycosides from C. orchioides rhizome and characterised them as curculigo saponin A-M.

The root stock are mucilaginous, sweet, cooling, bitter, emollient, diuretic, aphrodisiac, depurative, alternative, appetiser, carminative, viriligenic, antipyretic and tonic (Sivarajan and Indira, 1994; Warrier et al, 1994).

The uterine stimulant activity of the flavone glycoside extracted from C. orchioides has been studied by Dhawan and Saxena (1958), Sharma et al (1975) and Dhar et al (1979).

The plant extract of C. orchioides showed hypoglycaemic, spasmolytic and anticancer properties (Dhar et al,1968). Phagocytic activity (Kubo et al, 1983) and immunoadjuvant activity (Oru et al, 1982) of phenolic glycosides, curculigoside isolated from the rhizome of the plant have been reported. Porwal and Mehta (1985) discussed the medicinal importance of the plant and its use in indigenous system of medicine as a tonic. Sharma et al (1991) reported the influence of MAK an ayurvedic food supplement constituting C. orchioides against Dimethyl benz anthracene induced mammary tumours in rats. Samanta (1992) reported the modulation of male infertility by Ayurvedic drug, which constitutes C. orchioides. Immunostimulant activity of C. orchioides has been demonstrated by Saxena (1992). Immunological activites of curculigo saponin G were assayed in mice and the results showed that it promoted proliferation of spleen lymphocyctes very significantly and increased the weight of the thymus in vivo in mice (Xu et al,1992).

Pharmacological studies in China, on the alcoholic extract obtained from the plant showed several active effects such as adaptogenic, anti-inflammatory, anticonvulsant, sedative, androgenic and immunopromoting activities (Xu et al, 1992).

Curculigo orchioides is distributed widely throughout the country. The demand of the raw materials and derivatives of the plant for the indigenous drug industries are satisfied mainly from the wild source, depleting the natural population and thus the species have become extinct or endangered. Ansari (1993) have reported C. orchioides as a threatened plant from Madhulia forest of Garakhpur. Augustin and Souza (1995) also considered the plant as an endangered species. As the information on the cultivation of C.orchioides is scanty, it is very necessary to develop suitable agrotechniques for the domestication and large-scale cultivation of the plant.... holostemma

A condition characterised by underactivity of the testes (see TESTICLE) or OVARIES – the gonads. The condition may be caused by a genetically based disorder resulting in an abnormally functioning gonad (primary hypogonadism) or by a malfunctioning PITUITARY GLAND that fails to produce an adequate amount of gonadotrophin hormone (see GONADOTROPHINS) – secondary hypogonadism. Those affected may fail to develop adequately the secondary characteristics of their sex: males will have delayed puberty, erectile impotence and infertility and also develop GYNAECOMASTIA; females also have delayed puberty, infertility, and sometimes HIRSUTISM.... hypogonadism

Underactivity of the PITUITARY GLAND. It can cause dwar?sm, delayed puberty, impotence, infertility, AMENORRHOEA, hypothyroidism (see THYROID GLAND, DISEASES OF), and hypoadrenalism. Causes include tumours, irradiation of the gland, SARCOIDOSIS, and necrosis associated with post-partum haemorrhage (Sheehan’s syndrome).... hypopituitarism

An imidazole (see IMIDAZOLES) antifungal drug available for both oral and topical use. Better absorbed orally than other imidazoles, it also has an anti-androgen e?ect which may give rise to GYNAECOMASTIA and IMPOTENCE in men. In view of its potential hepatotoxicity it should not be given orally for trivial infections, but reserved instead for SYSTEMIC fungal infections (see FUNGAL AND YEAST INFECTIONS).... ketoconazole

A foreign body found in living tissue viewed under a microscope. It is usually caused by faulty preparation of a specimen, with the result that disease or abnormality seems to be present.

Arti?cial Insemination

In this method of fertilisation, SEMEN is collected either by the husband (AIH) or by a donor (AID) through masturbation and introduced into the cervix (neck of the womb) by means of an instrument around the time of OVULATION.

AIH is thought to be particularly useful for men with retrograde ejaculation or erectile IMPOTENCE. AID may be considered when the partner’s sperm count is either very low or zero.

Insemination can be made with fresh or frozen semen. Donors should be tested for sexually transmitted diseases and their identity remain unknown to the infertile couple. The pregnancy rate over six months is 50–60 per cent. Arti?cial insemination is usually done at specially sta?ed centres with facilities to store semen and provide the individuals involved with appropriate counselling. Success rates are up to 70 per cent with fresh semen (used over a six-month period) and over 50 per cent with frozen semen.... artifact (artefact)

Astragalus tea is a good choice to improve the immune system and it also renders a pleasant beverage to consumers. Astragalus Tea description Astragalus is one of the most frequently used herbs in food supplements and remedies in China, well known as an immunity booster. It has been proved it enables the body to maintain its normal balance of health. Astragalus contains antioxidants, compounds that protect the body from free radicals, which can damage the human metabolism. This plant has anti-inflammatory properties and it is a natural antibiotic that destroys bacteria and viruses. Astragalus tea is made by brewing the roots of the abovementioned plant. Astragalus Tea may be intaken internally or applied topically to accelerate wounds to heal. Astragalus Tea brewing Astragalus tea can be served both hot and cold. To prepare the hot tea, steep one tea bag in hot water for 3 - 5 minutes. To prepare the iced tea, steep one tea bag in hot water for 3 - 5 minutes and refrigerate. 2 to 4 tea bags of Astragalus tea can be used daily. Astragalus Tea benefits Astragalus Tea can be successfully used to:

• improve the functions of the lungs, thereby it helps treating ailments as bronchitis, pneumonia and whooping cough
• help in the overall efforts to treat ulcers and tumors in the stomach
• reduce fatigue
• promote the healing of wounds
• strengthen the immune system
• remove fluid from the body
• relieve impotence and frigidity

Astragalus Tea is an adjuvant in treating heart problems. Astragalus Tea side effects Astragalus tea side effects are generally related to high doses consumption. Astragalus tea is a healthy beverage that can treat cancer, due to its high content of antioxidants which fight the free radicals, responsible for tumors growth and cancer cells spreading.... astragalus tea

Allspice, bay rum tree (Pimenta dioica).

Plant Part Used: Leaf, berry, essential oil.

Dominican Medicinal Uses: Leaves: tea for common cold, flu; externally: mashed and applied topically for arthritis, joint pain; multi-herb tincture: taken internally for impotence, infertility, sexually transmitted infections. Berries, essential oil: externally for joint pain.

Safety: Potential hypersensitivity to essential oil. Leaf extract: low to moderate toxicity when taken orally.

Contraindications: Lack of information on use in pregnancy, lactation or young children.

Laboratory & Preclinical Data: In vitro: antibacterial, antifungal (essential oil). In vivo: anti-inflammatory, anti-nociceptive (leaf extract).

* See entry for Canelilla in “Part 3: Dominican Medicinal Plant Profiles” of this book for more information, including references.... canelilla

Mostly used as a spice in Thai cuisine, few people know that Galangal herb can also be used for a tasty tea due to its properties. Learn more about its interesting impact on your health. About Galangal tea Galangal (also known as galanga, blue ginger, laos) is an East Asian tropical shrub with lance-like leaves, iris-like flowers, and reddish brown, woody rhizomes, belonging to the ginger family. Widely used in the Asian cuisine, few people know that there are two main types, both called lengkuas or laos : Lesser galangal and Greater galangal also called Galanga or Temulawak. In its raw form, galangals have a stronger taste than common ginger. It can be found as fresh root, dried root or dried, ground powder, tea or tincture. Galangal rhizomes are rich in a complex of compounds such as resins, eugenol, volatile oil, galangol, as well as kaempferid, galangal, alpinin, and carbohydrates. Rhizomes are aromatic and pungent with a ginger-sour-lemon flavor. You can drink galangal tea at any time, during the day. How to brew Galagal tea In order to prepare a tasty tea, it is recommended to use the galangal root, dried or powdered. Infuse 1/2 teaspoon of powdered rhizome in one cup of boiling water, steep 10-15 minutess and drink up to 3 cups a day.  If you choose the root in the first brew, you can reuse it several times afterwards. Galangal tea has an amazing flavor, either sweetened or not. Benefits of Galangal tea Galangal tea is famous for easing digestive problems and in some Asian countries it is considered perfect for physical, mental and spiritual health and it is even believed to have aphrodisiac properties. Although galangal root is a little bitter, galangal tea relieves bloating, constipation, sluggish digestion, and gas. This tea can induce a deeply meditative state as well as powerful vivid dreams. It is even perfectly easy to fall asleep after drinking a cup of galangal tea. Galangal tea has been used for centuries for its tonic properties as it can instantly reduce fever and indigestion or ease stomach cramps, nausea and vomiting. It has been used for sea sickness, headaches, spleen enlargement, catarrh, bronchitis, rheumatism, foot pains, liver and gall bladder disorders, sore gums, as well as a respiratory and heart stimulant, and as a treatment for impotence. It is also used as a body deodorizer and breath cleanser. Side effects of Galangal tea Galangal tea inhibits the release and action of pancreatic lipase, so do not associate it with digestive enzymes. Like most teas, it has precautions when it comes to children and pregnant or breastfeeding women. Galangal tea is basically good for your health but do not exceed 3 cups a day if you want to benefit from its healthy properties.... galangal tea

For a sweet tea, try the muira puama tea. As an herbal tea, it has many health benefits, especially for men. Read the article and find out more about the muira puama tea! About Muira Puama Tea The main ingredient of the muira puama tea is, of course, the muira puama herbal plant. It is a flowering plant with two species (Benth and Anselmino). Its origin can be found in the Amazonian rainforests, although at present it is grown in Europe, as well. The trees grow up to 4 meters, sometimes even taller. They have short-petioled leaves which are light green on upper surface and dark brown on lower surface. It has small, white flowers that have a similar scent to those of jasmine. How to prepare Muira Puama Tea In order to drink a cup of muira puama tea, pour boiling water in a cup that contains one teabag or a teaspoon of dried herbs. Cover the cup and let it steep for 2-4 minutes. Next, remove the teabag or tea herbs. If you want, you can add milk and honey to your cup of tea, to sweeten the taste. Muira Puama Iced Tea You can also enjoy muira puama tea during summertime, by preparing it as an iced tea. For 1 liter, you mainly need 5 teabags, 2 cups of boiling water, and a similar amount of cold water. Place the teabags into a teapot or a heat resistant pitcher, then pour the boiling water. Let it steep for about 5 minutes, while you fill a serving pitcher with cold water. Remove the tea bags and pour the tea into the serving pitcher. Add ice and more cold water to the serving pitcher. Sweeten it with honey, sugar or anything else that comes to your mind. Components of Muira Puama Tea Muira Puama tea’s components come from the herb with the same name. There are two medically active ones: long-chain fatty acids and alkaloid chemicals. Also, the bark and roots of the plant (which are used to make the tea) contain some of the following constituentsg: alpha-pinene, alpha-terpinene, beta-sitosterol, camphor, eugenol, imonene, linalool, stigmasterols, and various acids and essential oils. Muira Puama Tea Benefits The most important benefit of the muira puama tea is for men. After all, the muira puama herb is also known as the “Viagra of the Amazon”. That is because it helps with sexual impotence, by increasing the blood flow to the genital areas. It also helps in the treatment of male pattern baldness. Muira puama tea can be used as a tonic for nervous conditions and depressions. It is useful when it comes to improving one’s memory, especially among elders. The tea also increases your energy level, and improves mental focus and clarity. It is often used in the treatment for rheumatism and indigestion. It also helps women with treating the discomforts of menopause, as well as lessening the pain that comes with menstrual cramps. Muira Puama Tea side effects It is considered best to avoid drinking muira puama tea during pregnancy or when you are breast feeding. In both cases, it can affect the baby.The teaalsoincludes some enzymes which are harmful if you’re suffering from peptic ulcers. In this case, it is recommended that you not consume this type of tea. Consumption of muira puama tea can also lead to an increase in the blood pressure levels. For most people, it is only temporary, but it can be harmful for people with existing complications of blood pressure levels. If this is your case, it’s best that you consult your doctor first before you start drinking this tea. As muira puama acts as a stimulant, drinking too much muira puama tea may lead to anxiety and insomnia. It is generally advised that you not drink more than six cups of tea a day, no matter the type of tea. Other symptoms that you might get are headaches, loss of appetite, vomiting, diarrhea, dizziness, and irregular heartbeats.   Muira puama tea is clearly full of health benefits, especially for men. It is good for women, as well, as long as it is not consumed during pregnancy or breast feeding periods. Be careful not to get any side effects and you can enjoy this type of tea with no worries.... benefits of muira puama tea

Goat’s Rue Tea is a popular tea known for being an aphrodisiac, helping with male impotence. It is a perennial shrub that grows in parts of Europe, Eastern Russia, Iran and Asia. Goat’s rue (galega officinalis) has green leaves that are made up of lance-shaped leaflets and has pink flowers that grow in spikes. The constituents of goat’s rue are galegine, saponins, tannins, bitters, grlycosides, alkaloids and chromium. How To Make Goat’s Rue Tea To brew goat`s rue tea, place 1 teaspoon of the dried goat’s rue leaves and stems in 1 cup of boiled water. Let the mix steep for about 15 minutes and after that, strain it into your cup. You can drink Goat’s Rue Tea twice a day. Goat’s Rue Tea Benefits

• It is considered safe for breastfeeding women to drink Goat`s RueTea since it is said that it facilitates the proper flow of breast milk. However, consult your doctor before drinking this tea.
• Helps treat several bladder problems.
• Helpful in the treatment of diabetes since it can lower blood sugar.
• Regulates menstruation.
• Helpful in treating snakebites and intestinal parasites.
• Alleviates fever.
• Helps treating rheumatism.

Goat’s Rue Tea Side Effects

• Stop drinking Goat’s Rue Tea if you are experiencing nausea, vomiting or sweating.
• It may interfere with the effects of some medications.
• Avoid over-consumption!

Goat’s Rue Tea is an excellent tea, with many health benefits, being used especially as an aphrodisiac!... goat`s rue tea

The natural desire for sexual intercourse. Lack of desire or diminished libido may occur in any general medical illness as well as in endocrine diseases when there is a lack of production of the sex hormones. The strength or weakness of the sexual drive may be associated with psychiatric diseases; it may also be the result of certain drugs. It must be distinguished from IMPOTENCE, where the desire for intercourse is normal but the performance is defective due to the inability to achieve or maintain an erection.... libido

A smooth-muscle (see MUSCLE) relaxant once used to treat IMPOTENCE (erectile dysfunction). The drug is injected directly into the corpora caverosa (spongy, blood-?lled erectile tissue) of the PENIS. Men with psychogenic or neurological impotence may respond to this treatment. Its use is less common since SILDENAFIL (Viagra®) was introduced for the treatment of erectile dysfunction.... papaverine

Alpinia galanga

Zingiberaceae

San:Sugandhamula, Rasna;

Hin:Kulainjan; Mal:Aratta, Chittaratha;

Tam:Arattai;

Guj: Kolinjan;

Kan: Dumba-rasmi; Mar: Kosht-Kulinjan;

Tel: Pedda-dumparash-tram

Importance: The greater galangal, Java galangal or Siamese ginger is a perennial aromatic rhizomatous herb. This plant is cultivated for its rhizome in tropical areas of south and East India. Because of the presence of essential oil, the rhizomes are used in bronchial troubles and as a carminative. They are also useful in vitiated conditions of vata and kapha, rheumatoid arthritis, inflammations, stomatopathy, pharyngopathy, cough, asthma, hiccough, dyspepsia, stomachalgia, obesity, diabetes, cephalagia, tubercular glands and intermittent fevers. It is one of the ingredients of medicated “Pan” used for removing the foul smell of the mouth and getting relief in throat inflammation. In Ayurveda, “Rasna-saptak-kwath” and “Rasna-adikamath” are used as antiinflammatory decoctions. In Unani, it is an ingredient of aphrodisiac preparations, “Majun Mugawivi ma Mumsik”, “Majun Samagh”, and antispasmodic nervine tonic “Majun Chobchine” and “Lubab Motadil”. It is also used in “Arq Pan” as a cardiac stimulant and carminative.

Distribution: The Java galangal is mainly distributed in Eastern Himalayas and South-West India. This is very common in West Bengal, Bihar, Assam, Kerala, Karnataka and throughout the Western Ghats. It is cultivated also in these places. They are also found in countries like Sri Lanka and Malaya.

Botany: Alpinia galanga (Linn.) Willd. belongs to the family Zingiberaceae. It is a perennial herb, about 2m high with lower portion covered with smooth leaf sheaths. The leaves are broadly lanceolate, 30-60cm long and 10-15cm broad. The flowers are arranged in erect, terminal panicles. composed of numerous spreading dichotomous branches each with two to six, pale greenish-white faintly fragrant flowers. Fruits 1.25 cm long, oblong, constricted in the middle or even pear shaped, three sided and deep orange red in colour. Seeds are ash coloured, three angled, finely striated towards the hilum. Both the seeds and rhizomes have pungent aroma.

Apinia calcarata (Linn.) Willd is another species of the genus with much medicinal importance. It is shorter in stature but stronger in aroma than Alpinia galanga.

Agrotechnology: Siamese Ginger comes up well in tropical climate. It grows on a wide range of climates and soils. Well drained hilly areas and places of 1400m high altitude are good for its cultivation. This is commercially propagated vegetatively by rhizomes. The field should be ploughed to a good tilth. All the stones and pebbles should be removed. Organic manures at 10t/ha are applied during land preparation. Seedbeds are prepared with 1m breadth, 2m length and 15cm height. Small pits are made at 25cm spacing above the seedbeds and 5cm long rhizomes are planted. Seedbeds are covered with dried leaves. It is irrigated immediately after planting. Regular weeding is needed during the initial stages of crop growth. This is cultivated also as an intercrop in coconut or rubber plantations. Rhizomes are dug out after cutting the top portions when the crop reaches 1.5-2 years of maturity. The average yield is 10-15 tonnes of fresh rhizomes/ha and the driage is 25-30%. The collected rhizomes are washed and cut into pieces of 5cm long and dried in sun for 4 days before sale.

Properties and activity: The rhizome contains tannins and flavonoids, some of which have been identified as kaempferide, galangin and alpinin. Seeds contain 1’-acetoxychavicol acetate and 1’-acetoxy eugenol acetate, antiulcer principles caryophyllenols I and II, n-pentadecane, 7-heptadecane and fatty acid methyl esters. Rhizomes yield essential oil containing methyl cinnamate, cineole and d-pinene and sesquiterpenoids. Fresh rhizome yielded 18 monoterpenoids of which -pinene, -pinene and limonene as major compounds and 17 oxygen containing monoterpenoids with cineol, terpinen-4-o1, and -terpineol as minor compounds.

The rhizomes are bitter, acrid, thermogenic, aromatic, nervine tonic, stimulant, revulsive, carminative, stomachic, disinfectant, aphrodisiac, expectorant, broncho-dilator, antifungal, febrifuge, antiinflammatory and tonic. Rhizome is CVS and CNS active, diuretic, hypothermic. Seed is antiulcerative. Rhizome spray in ether, over a space showed high knock down values against houseflies. Alcohol (50%) extract of rhizome is anti-amphetaminic. Unani physicians consider it good for impotence.... greater galangal

Hook.

Synonym: M. pruriens Baker non DC.

Family: Papilionaceae; Fabaceae.

Habitat: Throughotu India, including Andaman and Nicobar Islands.

English: Cowhage, Horse-eye Bean.

Ayurvedic: Aatmaguptaa, Kapikac- chuu, Rshabhi, Adhigandhaa, Ajadaaa, Kacchuraa, Laan- guli, Rshyaproktaa, Svaguptaa, Shyaamguptaa, Markati, Kanduraa, Kevaanch, Shuukashimbi.

Unani: Konchh.

Siddha/Tamil: Poonaikkaali.

Action: Seed—astringent, nervine tonic, local stimulant, used in impotence, spermatorrhoea, urinary troubles, leucorrhoea, traditionally used for male virility. Also used in depressive neurosis. Hair on fruit— vermifuge, mild vesicant; used for diseases of liver and gallbladder. Leaf—applied to ulcers. Pod— anthelmintic. Root and fruit—spasmolytic, hypoglycaemic. Root— CNS active.

The Ayurvedic Pharmacopoeia ofIn- dia recommends the seed in impotence and paralysis agitans; the root in vaginal laxity.

The seeds contain the alkaloids, mu- cunine, mucunadine, mucunadinine, prurieninine, pruriendine and nicotine, besides beta-sitosterol, gluthione, lecithin, vernolic and gallic acids. They contain a number of bioactive substances including tryptamine, alky- lamines, steroids, flavonoids, cou- marins and cardenolides. L-DOPA is present in the seed as well as in the stem, leaves and roots.

Major constituents of the hairs on the pod are amines such as 5-hydroxy- tryptamine (serotonin), and a proteolytic enzyme mucuanain. (Serotonin was present only in pods.)

Prurieninine slowed down heart rate, lowered blood pressure and stimulated intestinal peristalsis in experiments carried out on frogs. The spas- molysis of smooth muscles was caused by indole bases.

Seed diet produced hypoglycaemic effect in normal rats, however, such diet had insignificant effect on alloxan- treated rats.

There is some evidence that Cow- hage might be useful for chlorproma- zine-induced hyperprolactinemia in men. (Natural Medicines Comprehensive Database, 2007.) (Males with hy- perprolactinemia frequently face im- potency.) (Cured seeds are used in Indian medicine for male sexual dysfunction.)

Mucuna cochinchinensis Cheval.; synonym M. nivea (Roxb.) DC.; Sti- zolobium niveum Kuntze (cultivated in Bengal and Bihar for edible pods and seeds) is known as Lyon Bean (Khamach in Bengal). The pod yielded L-DOPA (0.06%).

Dosage: Cured seed—3-6 g (API, Vol. III); root—3-6 g powder for decoction (API, Vol. IV.)... mucuna prurita

The male organ through which the tubular URETHRA runs from the neck of the URINARY BLADDER to the exterior at the meatus or opening. URINE and SEMEN are discharged along the urethra, which is surrounded by three cylindrical bodies of erectile tissue, two of which (corpora cavernosa) lie adjacent to each other along the upper length of the penis and one (corpus spongiosum) lies beneath them. Normally the penis hangs down in a ?accid state in front of the SCROTUM. When a man is sexually aroused the erectile tissue, which is of spongy constituency and well supplied with small blood vessels, becomes engorged with blood.

This makes the penis erect and ready for insertion into the woman’s vagina in sexual intercourse. The end of the penis, the glans, is covered by a loose fold of skin – the foreskin or PREPUCE – which retracts when the organ is erect. The foreskin is sometimes removed for cultural or medical reasons.

A common congenital disorder of the penis is HYPOSPADIAS, in which the urethra opens somewhere along the under side; it can be repaired surgically. BALANITIS is in?ammation of the glans and foreskin. (See also REPRODUCTIVE SYSTEM; EJACULATION; IMPOTENCE; PRIAPISM.)... penis

Inadequate sexual response may be due to a lack of sexual desire (LIBIDO) or to an inadequate performance; or it may be that there is a lack of satisfaction or ORGASM. Lack of sexual desire may be due to any generalised illness or endocrine disorder, or to the taking of drugs that antagonise endocrine function (see ENDOCRINE GLANDS). Disorders of performance in men can occur during arousal, penetration and EJACULATION. In the female, DYSPAREUNIA and VAGINISMUS are the main disorders of performance. DIABETES MELLITUS can cause a neuropathy which results in loss of erection. IMPOTENCE can follow nerve damage from operations on the PROSTATE GLAND and lower bowel, and can be the result of neurological diseases affecting the autonomic system (see NERVOUS SYSTEM). Disorders of satisfaction include, in men, impotence, emission without forceful ejaculation and pleasureless ejaculation. In women such disorders range from the absence of the congestive genital response to absence of orgasm. Erectile dysfunction in men can sometimes be treated with SILDENAFIL CITRATE (Viagra®), a drug that recent research suggests may also be helpful to women with reduced libido and/or inability to achieve orgasm.

Sexual dysfunction may be due to physical or psychiatric disease, or it may be the result of the administration of drugs. The main group of drugs likely to cause sexual problems are the ANTICONVULSANTS, the ANTIHYPERTENSIVE DRUGS, and drugs such as metoclopramide that induce HYPERPROLACTINAEMIA. The benzodiazepine TRANQUILLISERS can reduce libido and cause failure of erection. Tricyclic ANTIDEPRESSANT DRUGS may cause failure of erection and clomipramine may delay or abolish ejaculation by blockade of alpha-adrenergic receptors. The MONOAMINE OXIDASE INHIBITORS (MAOIS) often inhibit ejaculation. The PHENOTHIAZINES reduce sexual desire and arousal and may cause di?culty in maintaining an erection. The antihypertensive drug, methyldopa, causes impotence in over 20 per cent of patients on large doses. The beta-adrenoceptorblockers and the DIURETICS can also cause impotence. The main psychiatric causes of sexual dysfunction include stress, depression and guilt.... sexual dysfunction

A rare condition in which wasting of the skin and the bones, IMPOTENCE, and loss of hair (ALOPECIA) occur as a result of destruction of the PITUITARY GLAND.... simmonds’ disease

Linn.

Family: Loganiaceae; Strychnaceae.

Habitat: Tropical India up to an altitude of 360 m.

English: Nux vomica.

Ayurvedic: Kapilu, Kaakatin- duka, Kaakendu, Kaakapiluka, Vishamushtikaa, Vishamushti, Vishatinduka, Kuchilaa, Ksuchalaa.

Unani: Azaraaqi, Kuchlaa.

Siddha: Yettikkottai.

Action: Nervine tonic and a potent CNS stimulant.

Seeds—used in emotional disorders, insomnia, hysteria, epilepsy, paralytic and neurological affections, retention or nocturnal incontinence of urine, spermatorrhoea, sexual debility and impotence, general exhaustion; as antidote to alcoholism; GIT disorders. Bark—juice given in acute dysentery, diarrhoea and colic. Root—given in intermittent fevers. In Chinese medicine a paste made of Nux vomica seeds is applied topically for treating facial paralysis.

Included among unapproved herbs by German Commission E.

The Ayurvedic Pharmacopoeia ofIn- dia recommends detoxified seeds in paralysis, facial paralysis, sciatica and impotency.

The seeds contain indole alkaloids, the major one is strychnine (approx. 50% of the alkaloids); others include strychnine N-oxide, brucine and its N-oxide, alpha-and beta-colubrine, condylocarpine, diaboline, geissoschi- zine, icajine, isostrychnine, normacu- sine, novacine, pseudobrucine, pseu- do-alpha-colubrine, pseudo-beta-col- ubrine, pseudostrychnine and vom- icine (3-hydro-beta-colubrine). Loga- nin is also present. Pseudostrychnine is non-toxic. The alkaloidal content of the seeds ranges from 1.8 to 5.3%.

The leaves contain strychnine and brucine (together 1.6%), strychnine 0.025%; vomicine is the major constituent of leaves. The bark contains 9.9% total alkaloids (brucine 8%, strychnine 1.58%); pseudostrychnine, pseudobrucine and beta-colubrine in small amounts. The roots contain 0.99% alkaloids (brucine 0.28%, strychnine 0.71%).

Strychnine, when tested for an- tiulcer activity in shay rat model at a dose of 0.25 mg/kg body weight, complete absence of ulceration was observed which was comparable to cime- tidine. Exhausted Nux-vomica powder at a dose of 20 mg/kg body weight, and brucine at a dose of 0.25 mg/kg body weight gave protection similar to strychnine.

Orally, 30-50 mg Nux-vomica (5 mg strychnine) is toxic.

Dosage: Detoxified seed—60- 125 mg. (API, Vol. IV.)... strychnos nux-vomica

Strychnos nux-vomica

Loganiaceae

San: Karaskara;

Hin: Kajra, Kuchila;

Mal: Kanjiram; ;

Tam: Itti, Kagodi, Kanjirai Mar:Jharkhatchura;

Kan: Hemmushti, Ittangi;

Tel: Mushti, Mushidi; Ori: Kora, Kachila

Importance: It is a large deciduous tree, with simple leaves and white fragrant flowers.

Strychnos is highly toxic to man and animals producing stiffness of muscles and convulsions, ultimately leading to death. However, in small doses it can also serve as efficacious cure forms of paralysis and other nervous disorders. The seeds are used as a remedy in intermittent fever, dyspepsia, chronic dysentery, paralytic and neuralgic affections, worms, epilepsy, chronic rheumatism, insomnia and colic. It is also useful in impotence, neuralgia of face, heart disease, spermatorrhoea, skin diseases, toxins, wounds, emaciation, cough and cholera. Leaves are applied as poultice in the treatment of chronic wounds and ulcers and the leaf decoction is useful in paralytic complaints. Root and root bark used in fever and dysentery (Nadkarni, 1982; Kurup et al, 1979).

Distribution: The plant is distributed throughout India in deciduous forests up to 1200m. It is also found in Sri Lanka, Siam, Indochina and Malaysia.

Botany: Strychnos nux-vomica Linn. is a large tree belonging to the family Loganiaceae. Leaves are simple, opposite, orbicular to ovate, 6-11.5x6-9.5cm, coriaceous, glabrous, 5 nerved, apex obtuse, acute or apiculate, transverse nerves irregular and inconspicuous. Inflorescence is many flowered terminal cymes, 2.5-5cm across. Bracts (5mm) and bracteoles (1.5mm) small. Flowers are white or greenish white and fragrant. Calyx 5 lobed, pubescent and small (2mm). Corolla salver shaped, tube cylindrical slightly hairy near the base within and greenish white, tube much elongate than the lobes. Tube 7mm and lobes 2.5mm long. Lobes 5 and valvate. Stamens 5, filaments short, 0.1mm long. Anthers 1.5mm subexerted, linear oblong. Ovary 1.5 mm, pubescent, 2 celled, ovules one to many. Style 9mm, stigma capitate. Fruit is a berry, 5-6cm diameter, globose, indehiscent, thick shelled, orange red when ripe with fleshy pulp enclosing the seeds. Seeds 1-many, discoid, compressed, coin like, concave on one side and convex on the other, covered with fine grey silky hairs.

The leaf fall is during December (do not shed all the leaves at a time) and new foliage appears in February. Flowering is during March - April and fruiting during May - December. Fruits take about 8-9 months to mature.

Properties and activity: Strychnine and brucine are the most important and toxic alkaloids present in the plant. They occur not only in the seeds but also in roots, wood, bark, fruit pulp and hard fruit shells. The minor alkaloids present in the plant are vomicine, -colubrine, -colubrine, pseudostrychnine and N-methyl-sec-pseudobrucine (novacine). Loganin a glycoside is also present (Warnat, 1932; Martin et al, 1953; Guggisberg et al, 1966; Bisset and Chaudhary, 1974). Chatterji and Basa (1967) reported vomicine as the major constituent alkaloid along with unidentified alkaloid in leaves and identified another alkaloid kajine (N-methyl pseudostrychnine) from the leaves of very young plants.

Root bark of S. nux-vomica yeilded 4-hydroxy-3-methoxy strychnine, 4 hydroxy strychine, nor-macusine, a new alkaloid 12 , 13 dihydro-12 -hydroxy isostrychnine named protostrychnine (Baser et al, 1979) methoxy strychnine, and mavacurine (Guggisberg et al, 1966). Leaves and root bark also yeilded 11 new alkaloids. 10-hydroxy strychnine, 3-12-dihydroxystrychnine, 12-hydroxy–11- methoxy strychnine, 3-12-dihydroxy- 11-methoxy strychnine,12-hydroxy strychnine-N- oxide 12-hydroxy-11-methoxy strychnine- N-oxide-19,20–dihydro isostrychnine, 16 , 17 dihydro-17 -hydroxy isostrychnine, O- methyl-macusine B, 16-epi-o-methyl–macusine B and normelinone B (Baser and Bisset, 1982).

De and Datta (1988) isolated 5 tertiary indole alkaloids viz. strychnine, brucine, vomicine, icajine and novacine from S.nux-vomica flowers. Bisset et al (1989) isolated and identified two phenolic glycosides salidroside and cuchiloside – a compound consisting of salidroside and an attached xylose unit, from the fruit of S.nux-vomica.

Rodriguez et al (1979) isolated an indole alkaloid from the seeds of S. nux- vomica and identified as a 3-methoxy icajine. A new alkaloid 15-hydroxy strychnine has been isolated from the seeds and the structure of the alkaloid established by spectroscopic data (Galeffi et al, 1979). Cai et al (1990a) isolated 4 new alkaloids isobrucine, isobrucine N-oxide, isostrychnine N-oxide and 2 hydroxy–3-methoxy strychnine from the heat treated seeds of S. nuxvomica and the structure of the alkaloids were determined by 13 CNMR (Cai et al, 1994). Cai et al (1990 b) studied the changes in the alkaloid composition of the seeds during drug processing. Saily et al (1994) determined the mineral elements in Strychnos nux-vomica. Corsaro et al (1995) reported polysaccharides from the seeds of Strychnos species.

Seeger and Neumann (1986) reviewed the physico-chemical characteristics, occurrence, identification, utilisation, poisoning, toxicity, kinetics, differential diagnosis and therapeutic uses of strychnine and brucine. Aspergillus niger, A. flavus and Pencillium citrinum showed regular association with Strychnos seeds and effectively deteriorated the alkaloid content of the seeds (Dutta, 1988; Dutta and Roy, 1992). Nicholson (1993) described the history, structure and synthesis of strychnine which occur in the seeds of S. nux-vomica. Rawal and Michoud (1991) developed a general solution for the synthesis of 2- azabicyclo (3.3.1) nonane substructure of Strychnos alkaloids.

Villar et al (1984) and Hayakawa et al (1984) developed HPLC method for the analysis of strychnine and brucine. Graf and Wittliner (1985), Kostennikova (1986) and Gaitonde and Joshi (1986) suggested different methods for the assay of strychnine and brucine. Biala et al, (1996) developed new method for the assay of alkaloids in S. nux- vomica.

The seeds are bitter, acrid, alexeteric, aphrodisiac, appetiser, antiperiodic, anthelmintic, digestive, febrifuge, emmenagogue, purgative, spinal, respiratory and cardiac stimulant and stomachic. The bark is bitter, and tonic and febrifuge (Nadkarni, 1954; Kurup et al, 1979; Warrier et al, 1996).

The quarternery alkaloid from the root bark of the Sri Lankan plant exhibited muscle-relaxant activity (Baser and Bisset, 1982). Antimicrobial activity of indole alkaloid isolated from the Strychnos nux-vomica was studied by Verpoorte et al, 1983. Shukla et al (1985) evaluated the efficacy of Rasnadigugglu compound consisting of S. nux-vomica, on rheumatoid arthritis and found to be effective in reducing inflammatory oedoma and rheumatoid arthritis. It also exhibited analgesic activity. A compound Unani formulation containing S. nux-vomica significantly attenuated withdrawal intensity in morphine dependent rats (Zatar et al, 1991). Shahana et al (1994) studied the effect of Unani drug combination (UDC) having Strychnos nux-vomica on the abstinence syndrome in moderately and severely morphine dependent rats. The UDC strikingly suppressed the abstinence syndrome was seen to possess central depressant and analgesic action.

Melone et al (1992) reported brucine-lethality in mice. Panda and Panda (1993) and Satyanarayanan et al (1994) reported antigastric ulcer activity of nux vomica in Shay rats. Banerjee and Pal (1994) reported the medicinal plants used by the tribals of plain land in India for hair and scalp preparation and S. nux-vomica being used to cure alopecia (baldness) by the tribals. Tripathi and Chaurasia (1996) studied the effect of S. nux-vomica alcohol extract on lipid peroxidation in rat liver.... strychnine tree

While tea generally has plenty of health benefits, some types of tea have a few benefits especially useful to men. They are meant to treat particular problems only men have to deal with. Discover more about tea for men! Why drink tea for men While medication is known to treat various health problems, tea can work as an important treatment, as well. As a natural beverage, it helps with problems from impotence to erectile disorders. Some types of tea can even work as an aphrodisiac. It’s interesting that the health benefits aren’t related only to the sexual organ and its functions. One type of tea also helps with male pattern baldness! Tea for men Pygeum bark tea is known for its health benefits when it comes to men. It helps with impotence, as it can increase the quantity and quality of the sperm. It can work as an aphrodisiac, and it is also added in the treatment for benign prostatic hyperplasia. Muira puama tea also works as an aphrodisiac, along with damiana tea and ginseng tea. Besides enhancing the sexual performance, muira puama tea has another benefit, quite interesting as well: it helps treat male pattern baldness. Catuaba tea and tribulus tea also help with impotence, while saw palmetto tea and red root tea are added to the treatment for benign prostate enlargement. Also, in the case of prostatitis, you can drink catuaba tea and saw palmetto tea. Rhodiola tea and maca tea help with erectile dysfunction, while tribulus tea and shatavari tea can help with other erectile disorders. Side effects of tea for men Despite the various health benefits these types of tea might have, you have to be careful when drinking some of these teas for men. Some can lead to a few side effects, as well. Muira puama tea, for example, shouldn’t be drunk by people with existing complications of blood pressure levels. It might increase the blood pressure and lead to unwanted problems. Also, as it acts as a stimulant, overconsumption can lead to anxiety and insomnia. Overconsumption of pygeum bark tea may also lead to various side effects: stomach discomfort, diarrhea, constipation, nausea, dizziness, headaches, or visual disturbances. It is best to talk with your doctor first, in order to make sure the tea you choose won’t interfere with any medication you might be taking. Also, be careful if you’re scheduled for a surgery: consumption of tea can lead to excessive bleeding during and after the surgery. Make sure you stop drinking tea two weeks before the surgery. Particular types of tea can have many health benefits, even for men. It can help with various health problems, which should encourage men to drink more tea - especially tea for men!... tea for men

Linn.

Family: Verbenaceae.

Habitat: Mediterranean region; South-West Asian countries, up to Pakistan. (Seeds are imported from Iran.)

English: Monk's Pepper-tree, Hemp tree.

Ayurvedic: Renukaa (seed). Renukaa and Harenukaa are synonyms in Indian medicine.

Unani: Sambhaalu.

Action: Dried ripe fruit—acts on the anterior pituitary gland, reducing FSH and increasing LSH; stimulates production of progesterone by reducing oestrogen; used as a substitution therapy in primary and secondary corpus luteum deficiency. Used for premenstrual syndrome, for regulating hormones in amenorrhoea and for bleeding between periods; also as a galactagogue and to assist bust development.

The herb is also used in the treatment of premature old age due to sexual excess, nervous debility and impotence (as a homoeopathic drug). Vitex agnus extract is found to lower prolactin levels in men (the decrease in prolactin levels results in improved sexual performance. Males with hyperprolacti- naemia frequently face impotence).

Key application: In irregularities of menstrual cycle, premenstrual complaints, mastodynia. (German Commission E.) As a hormonal modulator. (The British Herbal Pharmacopoeia.)

The methanolic extract of the flowering stems of Vitex agnus-castus yielded iridoids, angnucastoside-A, B and C, in addition to aucubin, agnuside, mussaenosidic acid and 6'-O-p-hy- droxybenzoylmussaenosidic acid, and phenylbutenone glucoside, myzoden- drone.

Dopaminergic compounds, present in the herb, are clinically important compounds which improve premenstrual mastodynia and other symptoms of premenstrual syndrome.

The herb may counteract birth control pills. (Sharon M. Herr.)... vitex agnus-castus

This substance is derived from the bark of Pausinystalia yohimbie, a West African tree. Once widely used as an aphrodisiac – an action for which there is no good evidence, it is now being used in the treatment of certain cases of postural HYPOTENSION and for the treatment of IMPOTENCE.... yohimbine

Popular Brazilian folk remedy. Two species. Juniperus brasiliens.

Keynote: aphrodisiac.

Action: brain and nerve stimulant, aphrodisiac for men and women.

Uses: Sexual weakness, male impotence, nervous debility and exhaustion.

Preparation. Ground bark: half-1 teaspoon to each cup boiling water; infuse 15 minutes. Half-1 cup freely. ... catuaba

Trace element. RDA 0.15 to 0.5mg.

Deficiency. Sexual impotence in aged men. Decayed teeth, allergy, palpitation.

Believed to be linked with cancer of the gullet in China where soil is deficient in this element.

Body effects. Male sexual libido, dental health, iron metabolism, function of some enzymes.

Sources. Most foods. Liver, oats, buckwheat, barley, wholegrains, lima beans, sunflower seeds, pulses, Soya beans and flour.

Note: High levels of uric acid (a cause of gout and gravel) have been linked with a high content of the element in some native soils – especially in Armenia. ... molybdenum

Liriosma ovata, Miers. Root.

Keynote: impotence.

Action: aphrodisiac.

Uses: impotence, infertility, neurasthenia.

Preparations: Average dose, half-2 grams, thrice daily.

Decoction: half-1 teaspoon to each cup water gently simmered 20 minutes; dose one-third-1 cup. Liquid Extract BHP (1983): 1:1 in 60 per cent alcohol. Dose, half-2ml. ... muira-puama

Curzon. Turnera diffusa Willd. Leaves and stems.

Constituents: flavonoids, volatile oil, arbutin.

Action: aphrodisiac, antidepressant, diuretic, stomachic, thymoleptic BHP (1983), stimulating tonic to the central nervous system and reproductive organs.

Uses: To enhance sexual performance, especially in the male. Impotence, frigidity, sterility, prostatitis, physical weakness and nervous exhaustion. Depression, anxiety states.

Combines well with Skullcap and Oats for senile dementia and feeble constitution. Traditional combination: (equal parts), Damiana, Saw Palmetto and Kola.

Preparations: Thrice daily.

Tea. 1 teaspoon to each cup boiling water; infuse 15 minutes. Half-1 cup.

Liquid extract. Half-1 teaspoon.

Tincture. 1-2 teaspoons, in water.

Tablets/capsules. One 300mg capsule or capsules after meals thrice daily. ... damiana

Trigonella foenum-graecum L. German: Griechisches Bockshorn. French: Fenugrec. Italian: Fieno greco. Indian: Methi. Arabian: Halbah. Iranian: Shembalita. Malayan: Halba. Seeds.

Properties similar to Irish Moss.

Constituents: flavonoids, volatile oil, saponins, alkaloids.

Action: leaves a soothing protective coating over irritated surfaces (internal demulcent, external emollient); nutrient, anti-inflammatory, galactagogue, hypoglycaemic. A natural lubricant for the colon. Oxytocic. Febrifuge. “A stimulating effect on bone healing.” (Hamdard Medicus, Oct/Dec 1988, Vol XXXI No 4)

Uses: Soothing and healing to mucosa of stomach, intestines. Gastric and duodenal ulcer. Diverticulosis, dysentery, colitis, diarrhoea, irritable bowel, fistula, Crohn’s disease. Weak digestion, poor appetite and general debility. Convalescence. Reduces level of blood sugar; transient effects in diabetes. For thin people anxious to put on weight. Cancer of the bowel, as a soothing mild analgesic. Sore gums, mouth ulcers, chronic cough, bronchitis. Has been used for kidney complaints in China as early as 1057 AD. Protection against thrombosis, embolism and angina. To increase milk in nursing mothers. Hiatus hernia, impotence.

Arabian medicine: “for alluring roundness of the female breast.”

Topical. Decoction used as a poultice for boils, abscesses, wounds.

Preparations: Freely.

Decoction. 1-2 teaspoons crushed seeds to each cup water gently simmered 15 minutes. Dose: half-1 cup; seeds should be eaten. More efficacious than alcoholic preparations.

Popular combination. (Tablets, powders) Fenugreek 275mg; Rhubarb root 6mg; Slippery Elm 9mg; Bayberry 6mg; Goldenseal 3mg.

Poultice. Powder or crushed seeds – see POULTICE.

Diet. Sprouts. Seeds readily germinate on a moistened surface to provide rich source of natural vitamins, lecithin and iron for addition to green salads. ... fenugreek

Oatstraw. Avena sativa L. Husks of oats. German: Evenhafer. French: Avoine. Spanish: Avena. Italian: Biada.

Constituents: glycosyl flavones, proteins, Vitamin E, oil, proteins.

Action: nerve restorative, antidepressant, tranquilliser, brain tonic. Cardiac tonic BHP (1983). Nutrient with selective action on brain and nerve cells. Source of minerals. Thymoleptic. Improves performance of athletes and stamina.

“Oats have the highest content of iron, zinc and manganese of all grain species.” (Dr A. Vogel)

Uses: Benzodiazepine, Valium or other drug addiction – with Valerian and Skullcap to assist withdrawal. Alcoholism. Nerve and physical weakness with depression and anxiety. Debility following illness; recovery from surgical operation. Neurasthenia. Tension and irritability through overwork. Headache with pain at back of the neck; sleeplessness, shingles, hyperactivity in children. Nerve tremor in the aged not caused by Parkinson’s or other nerve degenerative diseases. May be taken with benefit for general well-being in chronic nerve dyscrasies but with limited improvement in basic condition. Sometimes proves of benefit for schizophrenic tendency. Sexual weakness with night losses and impotence. Combines well with Saw Palmetto for spermatorrhoea. Combines with Valerian and Wood Betony for nerve weakness, to minimise attacks of petit mal, chorea and other convulsive states. Does not combine well with Passion flower or Cypripedium.

Contra-indicated in cases sensitive to gluten.

Preparations: Average dose, 1-2 grams or equivalent. Thrice daily. An older generation of herbalists prepared their tinctures and extracts from the green flowering unripe wild Oats as the effective constituent is unstable. Taken hot, effects are more immediate.

Tea: oatstraw: 1-2 teaspoons to each cup boiling water; infuse 15 minutes. Drink freely.

Tincture BHP (1983) 1 part to 5 parts 45 per cent alcohol. Macerate and shake daily for 8 days; dose, 1- 5ml.

Extracts, groats and oatmeal products are all beneficial but are not of the same efficacy as the fresh green plant.

Oatstraw bath: 2-3 handfuls oatstraw. Simmer in 2-3 litres water for 5 minutes; strain; add to bathwater. Liquid Extract: dose: 1-2ml in water.

Traditional combination: equal parts – Oats, Passion flower, Hops and Valerian. Diet. Porridge, but not to be eaten by the gluten intolerant.

Side-effects: none known. ... oats

A drug that is used in the treatment of glaucoma and, occasionally, to prevent or treat symptoms of mountain sickness. Possible adverse effects include lethargy, nausea, diarrhoea, and impotence.... acetazolamide

A prostaglandin drug used, prior to surgery, to minimize the effects of congenital heart defects in newborn babies. Alprostadil is also used as a treatment for impotence. It is administered by self-injection into the penis or as a gel introduced into the urethra to produce an erection.... alprostadil

An H2-receptor antagonist used as an ulcer-healing drug. Cimetidine promotes the healing of gastric and duodenal ulcers (see peptic ulcer) and reduces the symptoms of oesophagitis. Side effects include dizziness, fatigue, and rashes. More rarely, the drug causes impotence and gynaecomastia.... cimetidine

A thiazide diuretic drug used to reduce oedema associated with heart failure, kidney disorders, cirrhosis of the liver, and premenstrual syndrome, and to treat hypertension.

Side effects include lethargy, loss of appetite, leg cramps, dizziness, rash, and impotence.... cyclopenthiazide

Surgical removal of the bladder, used for treating bladder cancer (see bladder tumours).

It is followed by construction of an alternative channel for urine, usually ending in a stoma in the lower abdomen (see urinary diversion).

In men, the prostate gland and seminal vesicles are also removed, usually resulting in impotence.

In women, the uterus, ovaries, and fallopian tubes are removed.

After cystectomy an external pouch is worn for the collection of urine.... cystectomy

Conditions in which the normal process of erection of the penis is disrupted. They include total or partial failure to attain or maintain erection (see impotence), persistent erection in the absence of sexual desire (see priapism), and curving of the penis during erection (see chordee).... erection, disorders of

Nonmedical use of heroin.

Heroin addiction has many adverse effects on the user, including injection scars, skin abscesses, weight loss, impotence, and the risk of infection with hepatitis B, hepatitis C, and HIV through sharing needles.

Death commonly occurs from accidental overdose.... heroin abuse

A thiazide diuretic drug used to reduce oedema in people with heart failure, nephrotic syndrome, and cirrhosis. It is also given for hypertension. Adverse effects include leg cramps, dizziness, rash, and impotence. The drug may rarely cause gout and may aggravate diabetes mellitus.... hydrochlorothiazide

A beta-blocker drug that is used to treat hypertension and angina pectoris.

Possible adverse effects include indigestion, nausea, and, in rare cases, depression and temporary impotence.... labetalol

(NO) A gas that is produced both outside the body as a pollutant (for example, in car exhaust fumes), and inside the body, where it takes the form of a molecule that acts as a messenger between cells.

Nitric oxide causes blood vessels to dilate, affecting the flow of oxygenated blood and regulating blood pressure.

Overproduction of nitric oxide is associated with various disorders, including toxic shock, rheumatoid arthritis, and diabetes mellitus; underproduction may cause impotence and angina.

The control of nitric oxide is an important element of many drug treatments.... nitric oxide

Inability to achieve orgasm during sexual activity. It may be due to inhibited sexual desire (see sexual desire, inhibited) or inability to become aroused or maintain arousal (see frigidity; impotence). In men, there may be a problem achieving orgasm despite normal arousal (see ejaculation, disorders of). The problem is common in women; some may achieve orgasm through masturbation but not during sexual intercourse. Sometimes it is due to pain during intercourse (see intercourse, painful).

For both sexes, contributory factors include problems with technique or in the relationship, unfamiliarity with sexual responses, psychological problems (such as anxiety, early sexual trauma, or inhibitions), and fear of pregnancy.

Sex therapy, relationship counselling, and psychotherapy are sometimes helpful.... orgasm, lack of

A prosthesis inserted into the penis to help a man suffering from permanent impotence to achieve intercourse.

The various types include a silicone splint inserted in the tissues of the upper surface of the penis, and an inflatable prosthesis that is inflated by squeezing a small bulb in the scrotum.... penile implant

Persistent, painful erection of the penis without sexual arousal. Priapism occurs when blood does not drain from the spongy tissue of the penis, thus keeping the penis erect. This may be caused by clotting in the blood vessels due to a blood disorder or as a result of treatment for impotence. Urgent treatment is needed in order to avoid permanent damage. The treatment may involve withdrawal of blood from the penis with a needle.... priapism

A method taught to couples who are experiencing sexual difficulties caused by psychological rather than physiological factors. The aim of the technique is to make both partners more aware of pleasurable bodily sensations, and to reduce anxiety about performance. It is particularly effective in treating loss of sexual desire (see sexual desire, inhibited), or inability to achieve orgasm (see orgasm, lack of), and in helping men to overcome impotence or premature ejaculation (see ejaculation, disorders of).... sensate-focus technique

A rare degenerative disorder of unknown cause that progressively damages the autonomic nervous system. It begins gradually at age 60–70 and is more common in men. Symptoms include dizziness and fainting due to postural hypotension, urinary incontinence, impotence, reduced ability to sweat, and parkinsonism. The condition eventually leads to disability, and sometimes premature death. There is no cure or means of slowing degeneration, but many symptoms are relieved by drugs.... shy–drager syndrome

Commonly known by its brand name Viagra, a drug used in the treatment of impotence. Because of the risk of potentially serious side effects in certain people, the drug must only be used on medical advice.... sildenafil

n. one of a group of steroid hormones, including *testosterone and *dihydrotestosterone, that stimulate the development of male sex organs and male secondary sexual characteristics (e.g. beard growth, deepening of the voice, and muscle development). The principal source of these hormones is the testis (production being stimulated by *luteinizing hormone) but they are also secreted by the adrenal cortex (see dehydroepiandrosterone) and ovaries in small amounts. In women excessive production of androgens gives rise to *masculinization.

Naturally occurring and synthetic androgens are used in replacement therapy (to treat such conditions as delayed puberty in adolescent boys, *hypogonadism, and impotence due to testicular insufficiency) and as *anabolic agents. Side-effects include salt and water retention, increased bone growth, and masculinization in women. Androgens should not be used in patients with cancer of the prostate gland or in pregnant women. —androgenic adj.... androgen

n. removal of the sex glands (the testes or the ovaries). Castration in childhood causes failure of sexual development but when done in adult life (usually as part of hormonal treatment for cancer) it produces less marked physical changes in both sexes. Castration inevitably causes sterility but it need not cause impotence or loss of sexual desire.... castration

Myristica fragrans

FAMILY: Myristicaceae

SYNONYMS: M. officinalis, M. aromata, Nux moschata, myristica (oil), mace (husk), macis (oil).

GENERAL DESCRIPTION: An evergreen tree up to 20 metres high with a greyish-brown smooth bark, dense foliage and small dull-yellow flowers. ‘Mace’ is the name given to the bright red netlike aril or husk surrounding the nutmeg shell and seed, which is contained within the fleshy fruit.

DISTRIBUTION: Native to the Moluccas and nearby islands; cultivated in Indonesia, Sri Lanka and the West Indies, especially Grenada.

EXTRACTION: Essential oil by steam (or water) distillation from 1. the dried worm eaten nutmeg seed (the worms eat away all the starch and fat content); 2. the dried orangebrown aril or husk – mace; and 3. an oleoresin is also produced in small quantities by solvent extraction from mace. The oil is also distilled in the USA and Europe from the imported nutmegs.

OTHER SPECIES: Indonesia and Sri Lanka produce the so-called ‘East Indian’ nutmeg which is considered superior, while Grenada produces the ‘West Indian’ nutmeg – see also Botanical Classification.

HERBAL/FOLK TRADITION: Nutmeg and mace are widely used as domestic spices in the East and West. They have been used for centuries as a remedy mainly for digestive and kidney problems. In Malaysia they are used during pregnancy to strengthen and tone the uterine muscles. Grated nutmeg with lard is used for piles. A fixed oil of nutmeg is also used in soap and candle making.

Nutmeg is current in the British Herbal Pharmacopoeia indicated for flatulent dyspepsia, nausea, diarrhoea, dysentery, and topically for rheumatism.

ACTIONS: Analgesic, anti-emetic, antioxidant, antirheumatic, antiseptic, antispasmodic, aphrodisiac, carminative, digestive, emmenagogue, gastric secretory stimulant, larvicidal, orexigenic, prostaglandin inhibitor, stimulant, tonic.

CHARACTERISTICS: 1. A water-white or pale yellow mobile liquid with a sweet, warm-spicy odour and a terpeney top-note. 2. A water white or pale yellow mobile liquid with a sweet, warm-spicy scent. 3. An orange-brown viscous liquid with a fresh, spicy-warm, balsamic fragrance. It has good masking power.

They blend well with oakmoss, lavandin, bay leaf, Peru balsam, orange, geranium, clary sage, rosemary, lime, petitgrain, mandarin, coriander and other spice oils.

PRINCIPAL CONSTITUENTS: Mainly monoterpene hydrocarbons (88 per cent approx.): camphene, pinene, dipentene, sabinene, cymene, with lesser amounts of geraniol, borneol, linalol, terpineol, myristicin (4–8 per cent), safrol and elemincin, among others. Mace oil contains similar constituents but contains more myristicin.

SAFETY DATA: Both nutmeg and mace are generally non-toxic, non-irritant and non sensitizing. However, used in large doses they show signs of toxicity such as nausea, stupor and tachycardia, believed to be due to the myristicin content. ‘Large quantities are hallucinogenic and excitant to the motor cortex.’. On this basis nutmeg (especially the West Indian type) is probably safer to use than mace. Use in moderation, and with care in pregnancy.

AROMATHERAPY/HOME: USE

Circulation muscles and joints: Arthritis, gout, muscular aches and pains, poor circulation, rheumatism.

Digestive system: Flatulence, indigestion, nausea, sluggish digestion.

Immune system: Bacterial infection.

Nervous system: Frigidity, impotence, neuralgia, nervous fatigue.

OTHER USES: Used as a flavouring agent in pharmaceuticals, especially analgesic and tonic preparations. Nutmeg and mace oil are used in soaps, lotions, detergents, cosmetics and perfumes. Mace oleoresin is used in colognes and perfumes, especially men’s fragrances. Both oils and oleoresin are used in most major food categories, including alcoholic and soft drinks.... nutmeg

Solidago canadensis

FAMILY: Asteraceae

SYNONYMS: S. canadensis var. gilvocanescens, S. altissima, S. canadensis var. salebrosa, Canadian goldenrod, meadow goldenrod, common goldenrod, giant goldenrod, tall goldenrod, rough goldenrod.

GENERAL DESCRIPTION: Solidago canadensis is a herbaceous, perennial plant of the daisy family often found growing as a wildflower, commonly forming colonies. The stem is stiff and erect, growing up to 7 feet high with numerous branches and lance-shaped leaves. The attractive small yellow or golden flowers are held above the foliage in clusters, which bloom late in the season. Goldenrod is often unfairly blamed for causing hay fever in humans although the pollen causing these allergy problems is mainly produced by ragweed, another wild plant which blooms at the same time. Goldenrods have a reputation of being difficult to control due to their aggressive rhizomatous growth, which enables them to rapidly colonize large areas.

DISTRIBUTION: Native to North America, the herb occurs in most US states and Canadian provinces. It is found in a variety of habitats, and it typically is one of the first plants to colonize an area after disturbance (such as fire) but rarely persists once shrubs and trees become established and is found neither in very dry locations nor in waterlogged ones. In many parts of Europe, Japan and China, it is considered an invasive weed, often endangering local fauna.

OTHER SPECIES: The genus Solidago comprises over 140 varieties, many of which are very similar; it can even crossbreed with other plants! Nearly all are known simply as goldenrod, though some have specific folk names such as woundwort, Aaron’s rod and Blue Mountain tea. Most of the goldenrod species are native to North America although a few are native to Europe, Asia, North Africa and South America. The European goldenrod (S. virgaurea), was known as woundwort in England as it was used as an astringent remedy for treating wounds and bleeding. The sweet goldenrod (S. odora), a native of the US and Canada, is the species most frequently seen in herb gardens and is also used to produce an essential oil used by the perfumery industry. Sweet goldenrod also has a long history of medicinal use by Native Americans and was exported for tea in the nineteenth century.

HERBAL/FOLK TRADITION: The genus name Solidago derives from the Latin soldare, which means ‘to make whole’. Goldenrod has a long history of medicinal use especially by the Native Americans who used the plant for a wide range of conditions: infusions and compounds of the flowers and roots were used as emetics, sedatives and to counteract love potions, treat diarrhoea, fevers and the ’flu. The Shuswap used the plant in baths for women giving birth and the Zunis chewed crushed flowers to treat sore throats and drank infusions of the flowers for body pain. People of the Gosiute tribe ate the seeds and the Navajo people ate the roots. The Navajo also smoked the root with other plants and used the plant as a charm for success in gambling. The ground flowers were used on bee stings and a tea made to treat snakebite. During the Boston Tea Party, colonists drank goldenrod tea instead of English tea, which gave it the nick-name ‘Liberty Tea’. The tea is aromatic with a pleasing anise-like flavour as well as being a mildly astringent, carminative, diaphoretic, diuretic, febrifuge and stimulant.

Traditionally the herb has also been used for respiratory conditions and urinary tract infections. In the Swiss Pharmacopoeia, Goldenrod essential oil is indicated for supporting the circulatory system including cardiovascular problems like tachycardia as well as urinary tract and liver function. Goldenrod has also been approved by the German Commission as a natural anti-inflammatory, diuretic and antispasmodic in the treatment of urinary tract conditions. It is also reputed to be a lymphatic system conditioner, a regulator of the autonomic nervous system, with relaxing and calming effects valuable for hypertension.

According to the University of Montreal in Canada, goldenrod shows great potential in dealing with impotence. Although a little-known aromatherapy essential oil, it may have value due to its anti-allergy properties, for conditions like hay fever, allergic reactions, coughs and respiratory infections.

ACTIONS: Analgesic, anti-allergenic, antibacterial, antifungal, anti-infectious, anti-inflammatory, anti-oxidant, antihypertensive, antispasmodic, antiviral, astringent, diuretic, expectorant, febrifuge, immuno-stimulant, liver support/stimulant, mucolytic, sedative.

EXTRACTION: The essential oil is steam distilled from the goldenrod flower.

CHARACTERISTICS: A yellowish liquid with a strong fresh, balsamic-peppery and slightly bitter aroma with a woody undertone. It blends well with ravintsara, peru balsam, rosemary, pine, ginger, spruce and spice oils.

PRINCIPAL CONSTITUENTS: Mainly pinene, bornyl acetate, benzoates, myrcene, methyl chavicol, borneol and limonene. NB: Essential oil from a sample of S. odora contained up to 75 per cent methyl chavicol (estragole), which is known to be moderately toxic

SAFETY DATA: Generally considered non-toxic, non-irritating and non-sensitizing: possible skin sensitivity. Avoid during pregnancy and for children due to high levels of estragole in some chemotypes.

AROMATHERAPY/HOME: USE

Skin Care: Acne, cuts, inflammations of the skin, insect bites, sores, wounds.

Respiratory system: Catarrh, chills, coughs and colds, hay fever, allergies, laryngitis (as a gargle) and respiratory congestion, sinus infection, sore throat, ’flu.

Digestive system: Liver congestion, hepatitis and fatty liver.

Genito-urinary system: Urinary tract and bladder conditions.

Immune system: Boosts vitality.

Nervous system: Anxiety, depression, nervous tension, stress.

OTHER USES: The essential oil is used in pharmaceutical and in perfumery products, especially for scenting soaps. Mustard, orange and brown dyes can be obtained from the whole plant.... goldenrod

Rosa centifolia

FAMILY: Rosaceae

SYNONYMS: Rose maroc, French rose, Provence rose, hundred-leaved rose, Moroccan otto of rose (oil), French otto of rose (oil), rose de mai (absolute or concrete).

GENERAL DESCRIPTION: The rose which is generally used for oil production is strictly a hybrid between R. centifolia, a pink rose, and R. gallica, a dark red rose. This variety, known as rose de mai, grows to a height of 2.5 metres and produces an abundance of flowers with large pink or rosy-purple petals. There are two subspecies – one is more spiny than the other.

DISTRIBUTION: The birthplace of the cultivated rose is believed to be ancient Persia; now cultivated mainly in Morocco, Tunisia, Italy, France, Yugoslavia and China. The concrete, absolute and oil are mainly produced in Morocco; the absolute in France, Italy and China.

OTHER SPECIES: There are over 10,000 types of cultivated rose! There are several subspecies of R. centifolia, depending on the country of origin. Other therapeutic species are the red rose or apothecary rose (R. gallica) of traditional Western medicine, the oriental or tea rose (R. indica), the Chinese or Japanese rose (R. rugosa) and the Turkish or Bulgarian rose (R. damascena) which is also extensively cultivated for its oil. Recently rosehip seed oil from R. rubiginosa has been found to be a very effective skin treatment; it promotes tissue regeneration and is good for scars, burns and wrinkles. The wild rose (Eubatus rubus) is now also being used to produce a rare absolute with a rich, spicy-earthy fragrance. See also entry on damask rose and the Botanical Classification section.

HERBAL/FOLK TRADITION: The healing virtues of the rose have been known since antiquity and although roses are rarely used in herbal practice nowadays, up to the Middle Ages they played an essential part in the materia medica, and still

fulfil an important role in Eastern medicine. They were used for a wide range of disorders, including digestive and menstrual problems, headaches and nervous tension, liver congestion, poor circulation, fever (plague), eye infections and skin complaints. ‘The symbolism connected with the rose is perhaps one of the richest and most complex associated with any plant ... traditionally associated with Venus, the Goddess of love and beauty, and in our materialistic age the Goddess is certainly alive and well in the cosmetics industry for rose oil (mainly synthetic) is found as a component in 46% of men’s perfumes and 98% of women’s fragrances.’.

The French or Moroccan rose possesses narcotic properties and has the reputation for being aphrodisiac (more so than the Bulgarian type), possibly due to the high percentage of phenyl ethanol in the former. For further distinctions between the different properties of rose types, see damask rose.

ACTIONS: Antidepressant, antiphlogistic, antiseptic, antispasmodic, anti-tubercular agent, antiviral, aphrodisiac, astringent, bactericidal, choleretic, cicitrisant, depurative, emmenagogue, haemostatic, hepatic, laxative, regulator of appetite, sedative (nervous), stomachic, tonic (heart, liver, stomach, uterus).

EXTRACTION: 1. Essential oil or otto by water or steam distillation from the fresh petals. (Rose water is produced as a byproduct of this process.) 2. Concrete and absolute by solvent extraction from the fresh petals. (A rose leaf absolute is also produced in small quantities in France.)

CHARACTERISTICS: 1. The oil is a pale yellow liquid with a deep, sweet, rosy-floral, tenacious odour. 2. The absolute is a reddish orange viscous liquid with a deep, rich, sweet, rosy-spicy, honeylike fragrance. It blends well with jasmine, cassie, mimosa, neroli, geranium, bergamot, lavender, clary sage, sandalwood, guaiacwood, patchouli, benzoin, chamomile, Peru balsam, clove and palmarosa.

PRINCIPAL CONSTITUENTS: It has over 300 constituents, some in minute traces. Mainly citronellol (18–22 per cent), phenyl ethanol (63 per cent), geraniol and nerol (10–15 per cent), stearopten (8 per cent), farnesol (0.2–2 per cent), among others.

SAFETY DATA: Non-toxic, non-irritant, non-sensitizing.

AROMATHERAPY/HOME: USE

Skin care: Broken capillaries, conjunctivitis (rose water), dry skin, eczema, herpes, mature and sensitive complexions, wrinkles.

Circulation muscles and joints: Palpitations, poor circulation.

Respiratory system: Asthma, coughs, hay fever.

Digestive system: Cholecystitis, liver congestion, nausea.

Genito-urinary system: Irregular menstruation, leucorrhoea, menorrhagia, uterine disorders.

Nervous system: Depression, impotence, insomnia, frigidity, headache, nervous tension and stress-related complaints – ‘But the rose procures us one thing above all: a feeling of well being, even of happiness, and the individual under its influence will develop an amiable tolerance.’.

OTHER USES: Rose water is used as a household cosmetic and culinary article (especially in Persian cookery). The concrete, absolute and oil are employed extensively in soaps, cosmetics, toiletries and perfumes of all types – floral, oriental, chypres, etc. Some flavouring uses, especially fruit products and tobacco.... rose, cabbage

Salvia sclarea

FAMILY: Lamiaceae (Labiatae)

SYNONYMS: Clary, clary wort, muscatel sage, clear eye, see bright, common clary, clarry, eye bright.

GENERAL DESCRIPTION: Stout biennial or perennial herb up to 1 metre high with large, hairy leaves, green with a hint of purple, and small blue flowers.

DISTRIBUTION: Native to southern Europe; cultivated worldwide especially in the Mediterranean region, Russia, the USA, England, Morocco and central Europe. The French, Moroccan and English clary are considered of superior quality for perfumery work.

OTHER SPECIES: Closely related to the garden sage (S. officinalis) and the Spanish sage (S. lavendulaefolia), which are both used to produce essential oils. Other types of sage include meadow clary (S. pratensis) and vervain sage (S. verbenaca). Clary sage should not be confused with the common wayside herb eyebright (Euphrasia).

HERBAL/FOLK TRADITION: This herb, highly esteemed in the Middle Ages, has now largely fallen out of use. It was used for digestive disorders, kidney disease, uterine and menstrual complaints, for cleansing ulcers and as a general nerve tonic. The mucilage from the seeds was used for treating tumours and for removing dust particles from the eyes.

Like garden sage, it cools inflammation and is especially useful for throat and respiratory infections.

ACTIONS: Anticonvulsive, antidepressant, antiphlogistic, antiseptic, antispasmodic, aphrodisiac, astringent, bactericidal, carminative, cicatrisant, deodorant, digestive, emmenagogue, hypotensive, nervine, regulator (of seborrhoea), sedative, stomachic, tonic, uterine.

EXTRACTION: Essential oil by steam distillation from the flowering tops and leaves. (A concrete and absolute are also produced by solvent extraction in small quantities.)

CHARACTERISTICS: A colourless or pale yellowy-green liquid with a sweet, nutty herbaceous scent. It blends well with juniper, lavender, coriander, cardamon, geranium, sandalwood, cedarwood, pine, labdanum, jasmine, frankincense, bergamot and other citrus oils.

PRINCIPAL CONSTITUENTS: Linalyl acetate (up to 75 per cent), linalol, pinene, myrcene and phellandrene, among others. Constituents vary according to geographical origin – there are several different chemotypes.

SAFETY DATA: Non-toxic, non-irritant, nonsensitizing. Avoid during pregnancy. Do not use clary sage oil while drinking alcohol since it can induce a narcotic effect and exaggerate drunkenness. Clary sage is generally used in preference to the garden sage in aromatherapy due to its lower toxicity level.

AROMATHERAPY/HOME: USE

Skin care: Acne, boils, dandruff, hair loss, inflamed conditions, oily skin and hair, ophthalmia, ulcers, wrinkles.

Circulation muscles and joints: High blood pressure, muscular aches and pains.

Respiratory system: Asthma, throat infections, whooping cough.

Digestive system: Colic, cramp, dyspepsia, flatulence.

Genito-urinary system: Amenorrhoea, labour pain, dysmenorrhoea, leucorrhoea.

Nervous system: Depression, frigidity, impotence, migraine, nervous tension and stress-related disorders.

OTHER USES: The oil and absolute are used as fragrance components and fixatives in soaps, detergents, cosmetics and perfumes. The oil is used extensively by the food and drink industry, especially in the production of wines with a muscatel flavour.... sage, clary

Cananga odorata var. genuina

FAMILY: Annonaceae

SYNONYMS: Unona odorantissimum, flower of flowers.

GENERAL DESCRIPTION: A tall tropical tree up to 20 metres high with large, tender, fragrant flowers, which can be pink, mauve or yellow. The yellow flowers are considered best for the extraction of essential oil.

DISTRIBUTION: Native to tropical Asia, especially Indonesia and the Philippines. Major oil producers are Madagascar, Reunion and the Comoro Islands.

OTHER SPECIES: Very closely related to cananga (C. odoratum var. macrophylla), although the oil produced from the ylang ylang is considered of superior quality for perfumery work, having a more refined quality.

HERBAL/FOLK TRADITION: In Indonesia, the flowers are spread on the beds of newly married couples on their wedding night. In the Molucca Islands, an ointment is made from ylang ylang and cucuma flowers in a coconut oil base for cosmetic and hair care, skin diseases, to prevent fever (including malaria) and fight infections.

In the Victorian age, the oil was used in the popular hair treatment Macassar oil, due to its stimulating effect on the scalp, encouraging hair growth. The oil was also used to soothe insect bites, and is thought to have a regulating effect on cardiac and respiratory rhythm.

ACTIONS: Aphrodisiac, antidepressant, anti infectious, antiseborrhoeic, antiseptic, euphoric, hypotensive, nervine, regulator, sedative (nervous), stimulant (circulatory), tonic.

EXTRACTION: Essential oil by water or steam distillation from the freshly picked flowers. The first distillate (about 40 per cent) is called ylang ylang extra, which is the top grade. There are then three further successive distillates, called Grades 1, 2 and 3. A ‘complete’ oil is also produced which represents the total or ‘unfractionated’ oil, but this is sometimes constructed by blending ylang ylang 1 and 2 together, which are the two least popular grades. (An absolute and concrete are also produced by solvent extraction for their long-lasting floral-balsamic effect.)

CHARACTERISTICS: Ylang ylang extra is a pale yellow, oily liquid with an intensely sweet, soft, floral-balsamic, slightly spicy scent – a good oil has a creamy rich topnote. A very intriguing perfume oil in its own right, it also blends well with rosewood, jasmine, vetiver, opopanax, bergamot, mimosa, cassie, Peru balsam, rose, tuberose, costus and others. It is an excellent fixative. The other grades lack the depth and richness of the ylang ylang extra.

PRINCIPAL CONSTITUENTS: Methyl benzoate, methyl salicylate, methyl paracretol, benzyl acetate, eugenol, geraniol, linalol and terpenes: pinene, cadinene, among others.

SAFETY DATA: Non-toxic, non-irritant, a few cases of sensitization reported. Use in moderation, since its heady scent can cause headaches or nausea.

AROMATHERAPY/HOME: USE

Skin care: Acne, hair growth, hair rinse, insect bites, irritated and oily skin, general skin care.

Circulation muscles and joints: High blood pressure, hyperpnoea (abnormally fast breathing), tachycardia, palpitations.

Nervous system: Depression, frigidity, impotence, insomnia, nervous tension and stress-related disorders – ‘The writer, working with odorous materials for more than twenty years, long ago noticed that ... ylang ylang soothes and inhibits anger born of frustration.’.

OTHER USES: Extensively used as a fragrance component and fixative in soaps, cosmetics and perfumes, especially oriental and floral types; ylang ylang extra tends to be used in high-class perfumes, ylang ylang 3 in soaps, detergents, etc. Used as a flavour ingredient, mainly in alcoholic and soft drinks, fruit flavours and desserts.... ylang ylang