An alpha-adrenoreceptor-blocking drug used in the treatment of high blood pressure. It has several side-effects including sleepiness, dizziness, depression and failure to ejaculate. (See ALPHA ADRENERGIC BLOCKERS; ADRENERGIC RECEPTORS.)
n. an *alpha blocker drug used to treat high blood pressure and to relieve urinary retention due to benign enlargement of the *prostate gland. Possible side-effects can include drowsiness, nasal congestion, dry mouth, and failure of ejaculation.
Also called adrenoceptor-blocking agents or alpha blockers, these drugs stop the stimulation of alpha-adrenergic receptors at the nerve endings of the SYMPATHETIC NERVOUS SYSTEM by HORMONES with ADRENALINE-like characteristics. The drugs dilate the arteries, causing a fall in blood pressure, so they are used to treat HYPERTENSION and also benign enlargement of the PROSTATE GLAND. Examples of this group of drugs are doxazosin, indoramin, phentolamine and prazosin. The drugs should be used with caution as some may cause a severe drop in blood pressure when ?rst taken.... alpha adrenergic blockers
(alpha-adrenergic blocker) a drug that prevents the stimulation of alpha *adrenoceptors at the nerve endings of the sympathetic nervous system by noradrenaline and adrenaline: it therefore causes relaxation of smooth muscle, including widening of arteries (vasodilatation) and a drop in blood pressure. Alpha blockers include *doxazosin, *phentolamine, *phenoxybenzamine, *indoramin, *prazosin, *alfuzosin, and *tamsulosin.... alpha blocker
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