Infantile paralysis Health Dictionary

Paralysis, or PALSY, is loss of muscular power due to some disorder of the NERVOUS SYSTEM. Weakness – rather than total movement loss – is sometimes described as paresis. Paralysis may be temporary or permanent and may be accompanied by loss of feeling.

Paralysis due to brain disease The most common form is unilateral palsy, or HEMIPLEGIA, generally arising from cerebral HAEMORRHAGE, THROMBOSIS or EMBOLISM affecting the opposite side of the BRAIN. If all four limbs and trunk are affected, the paralysis is called quadraplegia; if both legs and part of the trunk are affected, it is called paraplegia. Paralysis may also be divided into ?accid (?oppy limbs) or spastic (rigid).

In hemiplegia the cause may be an abscess, haemorrhage, thrombosis or TUMOUR in the brain. CEREBRAL PALSY or ENCEPHALITIS are other possible causes. Sometimes damage occurs in the parts of the nervous system responsible for the ?ne control of muscle movements: the cerebellum and basal ganglion are such areas, and lack of DOPAMINE in the latter causes PARKINSONISM.

Damage or injury Damage to or pressure on the SPINAL CORD may paralyse muscles supplied by nerves below the site of damage. A fractured spine or pressure from a tumour may have this e?ect. Disorders affecting the cord which can cause paralysis include osteoarthritis of the cervical vertebrae (see BONE, DISORDERS OF), MULTIPLE SCLEROSIS (MS), MYELITIS, POLIOMYELITIS and MENINGITIS. Vitamin B12 de?ciency (see APPENDIX 5: VITAMINS) may also cause deterioration in the spinal cord (see also SPINE AND SPINAL CORD, DISEASES AND INJURIES OF).

Neuropathies are a group of disorders, some inherited, that damage the peripheral nerves, thus affecting their ability to conduct electrical impulses. This, in turn, causes muscle weakness or paralysis. Among the causes of neuropathies are cancers, DIABETES MELLITUS, liver disease, and the toxic consequences of some drugs or metals – lead being one example.

Disorders of the muscles themselves – for example, muscular dystrophy (see MUSCLES, DISORDERS OF – Myopathy) – can disturb their normal working and so cause partial or complete paralysis of the part(s) affected.

Treatment The aim of treatment should be to remedy the underlying cause – for example, surgical removal of a displaced intervertebral

disc or treating diabetes mellitus. Sometimes the cause cannot be recti?ed but, whether treatable or not, physiotherapy is essential to prevent joints from seizing up and to try to maintain some tone in muscles that may be only partly affected. With temporary paralysis, such as can occur after a STROKE, physiotherapy can retrain the sufferers to use their muscles and joints to ensure mobility during and after recovery. Patients with permanent hemiplegia, paraplegia or quadraplegia need highly skilled nursing care, rehabilitative support and resources, and expert help to allow them, if possible, to live at home.... paralysis

An outdated term for the tertiary stage of SYPHILIS.... general paralysis of the insane

Also known as salaam attacks, these are a rare but serious type of EPILEPSY, usually starting in the ?rst eight months of life. The spasms are short and occur as involuntary ?exing of the neck, arms, trunk and legs. They may occur several times a day. If the baby is sitting, it may collapse into a ‘salaam’ position; more usually there is a simple body jerk, sometimes accompanied by a sudden cry. An electroencephalogram (see ELECTROENCEPHALOGRAPHY (EEG)) shows a picture of totally disorganised electrical activity called hypsarrhythmia. The condition results from any one of many brain injuries, infections or metabolic insults that may have occurred before, during, or in the ?rst few months after birth. Its importance is that in most cases, the baby’s development is seriously affected such that they are likely to be left with a profound learning disability. Consequently, prompt diagnosis is important. Treatment is with CORTICOSTEROIDS or with certain anti-convulsants – the hope being that prompt and aggressive treatment might prevent further brain damage leading to learning disability.... infantile spasms

Paralysis of the lower arm, with wasting of the small muscles in the hand, and numbness of the fingers (excluding the thumb) and of the inside of the forearm.

Klumpke’s paralysis is caused by injury to the 1st thoracic nerve (one of the spinal nerves) in the brachial plexus, which is usually the result of dislocation of the shoulder.... klumpke’s paralysis

The sensation of being unable to move at the moment of going to sleep or when waking up, usually lasting only a few seconds. It may be accompanied by hallucinations. Sleep paralysis most often occurs in people with narcolepsy. (See also cataplexy.)... sleep paralysis

Inability to move a part of the body, accompanied by rigidity of the muscles. Causes of spastic paralysis include stroke, cerebral palsy, and multiple sclerosis. (See also paralysis.)... spastic paralysis

Weakness in part of the body following some types of epileptic seizure (see epilepsy).

The weakness may last for minutes, hours, or even days, but there is no lasting effect.

The cause is thought to be temporary damage to the motor cortex (the area of the brain that controls movement).... todd’s paralysis

See PARALYSIS; MOTOR NEURONE DISEASE (MND).... bulbar paralysis

Erb’s paralysis is a form of paralysis of the arm due to stretching or tearing of the ?bres of the brachial nerve plexus. Such damage to the brachial plexus may occur during birth, especially when the baby is unusually large, and it is found that the arm lies by the side of the body with elbow extended, forearm pronated, and the ?ngers ?exed. The infant is unable to raise the arm.... erb’s paralysis

Injury as a result of the stretching of a baby’s brachial plexus during its birth may cause partial paralysis of the arm with atrophy of the muscles of the forearm and hand.... klumpke’s paralysis

See PARKINSONISM.... paralysis agitans

Episodes of irritability, and excessive crying in otherwise healthy infants, thought to be due to spasm in the intestines.

A baby with an attack of colic cries or screams incessantly, draws up the legs towards the stomach, and may become red in the face and pass wind.

Colic tends to be worse in the evenings.

The condition is distressing but harmless.

Usually, it first appears at 3–4 weeks and clears up without treatment by the age of 12 weeks.... colic, infantile

A rare, inherited condition that affects young people. Periodic paralysis is characterized by episodes of muscle weakness, which vary in frequency from daily to every few years and last from a few minutes to a few hours. In some cases, there is a drop in the potassium levels in the blood; in others, the levels rise. A carbohydraterich meal may trigger an attack. The condition often clears up without treatment by age 40.... paralysis, periodic

paralysis of the facial nerve, causing weakness and loss of function of the muscles it serves. It occurs in *Bell’s palsy. The commonest cause is infection with the herpes simplex virus.... facial paralysis

adj. 1. denoting conditions occurring in adults that are recognizable in childhood, e.g. poliomyelitis (infantile paralysis) and infantile scurvy. 2. of, relating to, or affecting infants.... infantile

a condition in which attacks of sudden weakness and flaccidity occur in patients with *thyrotoxicosis, seen most often in males of Asian descent. The attacks last from hours to days; they can be prevented by potassium supplements and subsequent treatment of the thyrotoxicosis.... thyrotoxic periodic paralysis