Interstitial Pneumonia: From 1 Different Sources
(interstitial pneumonitis) an alternative name for *idiopathic pulmonary fibrosis used by lung pathologists to classify the different cellular types of the disease. The most common cellular pattern is usual interstitial pneumonia (UIP). A differing cellular pattern is seen in patients with nonspecific interstitial pneumonia (NSIP), who have a better prognosis than those with UIP. There are two variants of NSIP: cellular and fibrosing. The former has chronic inflammatory cells with minimal collagen deposition, while the latter consists of diffuse interstitial fibrosis with fewer inflammatory cells. It is believed that corticosteroid therapy can slow the progression of cellular to fibrosing NSIP.
Inflammation of lung tissue... pneumonia
Interstitial is a term applied to indi?erent tissue set among the proper active tissue of an organ. It is generally of a supporting character and formed of ?brous tissue. The term is also applied to the ?uid always present in this in a small amount, and to diseases which specially affect this tissue, such as interstitial keratitis.... interstitial
Also called Leydig cells, these cells are scattered between the SEMINIFEROUS TUBULES of the testis (see TESTICLE). LUTEINISING HORMONE from the anterior PITUITARY GLAND stimulates the interstitial cells to produce androgens, or male hormones.... interstitial cells
PNEUMONIA caused by a species of the genus of PROTOZOA, a parasitic micro-organism. Pneumocystis carinii causes an opportunistic infection in the lung which is dangerous to people whose immune system is impaired (see IMMUNITY), thus reducing their resistance to infections. People with AIDS/HIV or LEUKAEMIA have impaired immune systems and P. carinii is a major cause of death in the former. Fever, dry cough and breathlessness are among the symptoms; treatment is with high doses of antibiotic drugs such as CO-TRIMOXAZOLE or PENTAMIDINE.... pneumocystis pneumonia
Infection of the lung tissue by a VIRUS. Causes of this type of pneumonia include ADENOVIRUSES, COXSACKIE VIRUSES and in?uenza virus. Viral infections do not respond to ANTIBIOTICS and treatment is symptomatic, with antibiotics used only if the patient develops secondary bacterial infection. In a previously healthy individual the viral infection is usually self-limiting, but in vulnerable patients – the elderly or those with pre-existing disease – it can be fatal.... viral pneumonia
See PNEUMONIA.... broncho-pneumonia
The hydrogel that surrounds cells in soft tissues. It is a mucopolysaccaride starch gel, and the serum that leaves the blood capillaries flows through this gel, some to return to the exiting venous blood, some to enter the lymph system. There is an old medical axiom: the blood feeds the lymph, and the lymph feeds the cells. Interstitial fluid that flows through the starch colloid is this lymph.... interstitial fluid
Scarring of lung tissue mainly involving the alveoli. There are a number of causes, including occupational exposure to dusts and fibrosing alveolitis, which is an autoimmune disorder.... interstitial pulmonary fibrosis
any one of a group of community-acquired *pneumonias that do not respond to penicillin but do respond to such antibiotics as tetracycline and erythromycin. They include infection with Mycoplasma pneumoniae, Chlamydia psittaci (see psittacosis), and Coxiella burnetii (see Q fever).... atypical pneumonia
(BOOP) a disease entity characterized clinically by a flulike illness with cough, fever, shortness of breath, and late inspiratory crackles; there are specific histological features and patchy infiltrates on X-ray. It is sometimes the result of a viral infection, but may follow medication with certain drugs or be associated with connective-tissue disease, such as rheumatoid arthritis. The condition usually responds to oral corticosteroids; however, if a drug is implicated, it must be withdrawn.... bronchiolitis obliterans organizing pneumonia
(CAP) see pneumonia.... community-acquired pneumonia
see luteinizing hormone.... interstitial-cell-stimulating hormone
a chronic nonbacterial inflammation of the bladder accompanied by an urgent desire to pass urine frequently and bladder pain; it is sometimes associated with an ulcer in the bladder wall (Hunner’s ulcer). The cause is unknown and *contracture of the bladder eventually occurs. Treatment is by distension of the bladder under spinal or epidural anaesthetic, instillation of anti-inflammatory solutions into the bladder, and administration of steroids or *NSAIDs. Bladder enhancement or augmentation (see cystoplasty) may be required for a contracted bladder.... interstitial cystitis
(NSIP) see interstitial pneumonia.... nonspecific interstitial pneumonia
(UIP) see interstitial pneumonia; idiopathic pulmonary fibrosis.... usual interstitial pneumonia
disease of the *tubulointerstitium of the kidney. Acute interstitial nephritis (AIN) represents in many cases an allergic reaction to drugs (especially ampicillin, cephalexin, NSAIDs, allopurinol, and frusemide). AIN can also be associated with acute infections and autoimmune disease. Thirst and polyuria may be prominent, and renal function severely affected. In allergic cases, the use of steroids hastens recovery after the allergen has been removed. Chronic interstitial nephritis (CIN) is associated with progressive scarring of the tubulointerstitium, often with lymphocyte infiltration. Primary causes of CIN include gout, radiation nephropathy, sarcoidosis, *analgesic nephropathy, reflux nephropathy, chronic hypokalaemia and hypercalcaemia, and *Aristolochia-associated nephropathies. Management of CIN involves removal of the precipitating cause, where identified, and control of hypertension.... interstitial nephritis
Health Encyclopedia