Interstitial Radiotherapy: From 1 Different Sources
Treatment of a cancerous tumour by inserting radioactive material into the growth or into neighbouring tissue. Using this method, also called brachytherapy, radiation can be targeted at the diseased area.
Radioactive material (usually artificial radioisotopes) contained in wires, small tubes, or seeds is then implanted into or near the diseased tissue under general anaesthesia. The material is left in place for variable amounts of time depending on the radioactive substance and the tumour being treated. (See also intracavitary therapy; radiotherapy.)
A treatment which uses atomic particles and high energy rays to destroy cancerous cells.... radiotherapy
Interstitial is a term applied to indi?erent tissue set among the proper active tissue of an organ. It is generally of a supporting character and formed of ?brous tissue. The term is also applied to the ?uid always present in this in a small amount, and to diseases which specially affect this tissue, such as interstitial keratitis.... interstitial
Also called Leydig cells, these cells are scattered between the SEMINIFEROUS TUBULES of the testis (see TESTICLE). LUTEINISING HORMONE from the anterior PITUITARY GLAND stimulates the interstitial cells to produce androgens, or male hormones.... interstitial cells
The hydrogel that surrounds cells in soft tissues. It is a mucopolysaccaride starch gel, and the serum that leaves the blood capillaries flows through this gel, some to return to the exiting venous blood, some to enter the lymph system. There is an old medical axiom: the blood feeds the lymph, and the lymph feeds the cells. Interstitial fluid that flows through the starch colloid is this lymph.... interstitial fluid
Scarring of lung tissue mainly involving the alveoli. There are a number of causes, including occupational exposure to dusts and fibrosing alveolitis, which is an autoimmune disorder.... interstitial pulmonary fibrosis
see teletherapy.... external beam radiotherapy
(IGRT) the process of imaging during a course of radiation treatment to verify the internal position of the target in comparison to the initial planning scan. This enables adjustment of *treatment fields to improve coverage and allows the use of smaller treatment volumes. The possible methods for IGRT include cone beam CT, *tomotherapy, *cyberknife, and ultrasound and kilovoltage X-rays of implanted fiducial markers.... image-guided radiotherapy
(IMRT) radiotherapy using multiple beams with variable intensity across each field, resulting in dose distributions that can fit to concave shapes and thus reduce dose to surrounding healthy tissues and organs. It can be used to treat a wide range of cancers and can enable safe delivery of higher doses to tumours.... intensity-modulated radiotherapy
see luteinizing hormone.... interstitial-cell-stimulating hormone
a chronic nonbacterial inflammation of the bladder accompanied by an urgent desire to pass urine frequently and bladder pain; it is sometimes associated with an ulcer in the bladder wall (Hunner’s ulcer). The cause is unknown and *contracture of the bladder eventually occurs. Treatment is by distension of the bladder under spinal or epidural anaesthetic, instillation of anti-inflammatory solutions into the bladder, and administration of steroids or *NSAIDs. Bladder enhancement or augmentation (see cystoplasty) may be required for a contracted bladder.... interstitial cystitis
disease of the *tubulointerstitium of the kidney. Acute interstitial nephritis (AIN) represents in many cases an allergic reaction to drugs (especially ampicillin, cephalexin, NSAIDs, allopurinol, and frusemide). AIN can also be associated with acute infections and autoimmune disease. Thirst and polyuria may be prominent, and renal function severely affected. In allergic cases, the use of steroids hastens recovery after the allergen has been removed. Chronic interstitial nephritis (CIN) is associated with progressive scarring of the tubulointerstitium, often with lymphocyte infiltration. Primary causes of CIN include gout, radiation nephropathy, sarcoidosis, *analgesic nephropathy, reflux nephropathy, chronic hypokalaemia and hypercalcaemia, and *Aristolochia-associated nephropathies. Management of CIN involves removal of the precipitating cause, where identified, and control of hypertension.... interstitial nephritis
(NSIP) see interstitial pneumonia.... nonspecific interstitial pneumonia
(UIP) see interstitial pneumonia; idiopathic pulmonary fibrosis.... usual interstitial pneumonia
(interstitial pneumonitis) an alternative name for *idiopathic pulmonary fibrosis used by lung pathologists to classify the different cellular types of the disease. The most common cellular pattern is usual interstitial pneumonia (UIP). A differing cellular pattern is seen in patients with nonspecific interstitial pneumonia (NSIP), who have a better prognosis than those with UIP. There are two variants of NSIP: cellular and fibrosing. The former has chronic inflammatory cells with minimal collagen deposition, while the latter consists of diffuse interstitial fibrosis with fewer inflammatory cells. It is believed that corticosteroid therapy can slow the progression of cellular to fibrosing NSIP.... interstitial pneumonia
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