Groups of specialised cells distributed throughout the PANCREAS, that produce three hormones: INSULIN, GLUCAGON, and SOMATOSTATIN.
small groups of endocrine cells scattered through the material of the *pancreas. There are three main histological types: alpha (?) cells, which secrete *glucagon; beta (?) cells, which produce *insulin; and D cells, which release *somatostatin and *pancreatic polypeptide. [P. Langerhans (1847–88), German physician and anatomist]
overgrowth of cells of the *reticuloendothelial system. This includes disorders previously called histiocytosis X, including eosinophilic granuloma, Hand–Schüller–Christian disease, and Letterer–Siwe disease. [P. Langerhans (1847–88), German physician and anatomist]... langerhans cell histiocytosis