Isoagglutinin Health Dictionary

Isoagglutinin: From 1 Different Sources


(isohaemagglutinin) n. one of the antibodies occurring naturally in the plasma that cause *agglutination of red blood cells of a different group.
Health Source: Oxford | Concise Colour Medical Dictionary
Author: Jonathan Law, Elizabeth Martin

Agglutination

(clumping) n. the sticking together, by serum antibodies called agglutinins, of such microscopic antigenic particles as red blood cells or bacteria so that they form visible clumps. Any substance that stimulates the body to produce an agglutinin is called an agglutinogen. Agglutination is a specific reaction; in the laboratory, sera containing different known agglutinins provide an invaluable means of identifying unknown bacteria. When blood of different groups is mixed, agglutination occurs because serum contains natural antibodies (isoagglutinins) that attack red cells of a foreign group, whether previously encountered or not. This is not the same process as occurs in *blood coagulation.... agglutination

Blood Group

any one of the many types into which a person’s blood may be classified, based on the presence or absence of certain inherited antigens on the surface of the red blood cells. Blood of one group contains antibodies in the serum that react against the cells of other groups.

There are more than 30 blood group systems, one of the most important of which is the ABO system. This system is based on the presence or absence of antigens A and B: blood of groups A and B contains antigens A and B, respectively; group AB contains both antigens and group O neither. Blood of group A contains antibodies to antigen B; group B blood contains anti-A antibodies or *isoagglutinins; group AB has neither antibody and group O has both. A person whose blood contains either (or both) of these antibodies cannot receive a transfusion of blood containing the corresponding antigens. The table illustrates which blood groups can be used in transfusion for each of the four groups.

Blood group... blood group

Isoagglutinogen

n. one of the *antigens naturally occurring on the surface of red blood cells that is attacked by an isoagglutinin in blood plasma of a different group, so causing *agglutination.... isoagglutinogen

Isohaemagglutinin

n. see isoagglutinin.... isohaemagglutinin



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