Habitat: Native to tropical America. Now cultivated along with Cromandel Coast and in Travancore.
English: Physic Nut, Purging Nut.Ayurvedic: Vyaaghrairanda (var.), Sthula-eranda, Kaanan-eranda.Siddha/Tamil: Kattu Amanaku.Folk: Bagharenda (var.).Action: Seed—highly toxic. Nut— purgative. Plant—used for scabies, ringworm, eczema, whitlow, warts, syphilis. Stem bark—applied to wounds of animal bites; root bark to sores.
The protein of the seed contains the toxic albumin curcin (protein 18.0%, curcin 0.005%).Seed and seed oil—more drastic purgative than castor seed oil and milder than Croton tiglium oil.An aqueous (10%) infusion of leaves increased cardiac contraction is small doses. EtOH (50%) extract of aerial parts—diuretic and CNS depressant.The seed contain phorbol derivatives. The plant also contains cur- cosones and lathyrane diterpenes.