Juvenile polyp Health Dictionary

The immature life-cycle form of a jellyfish (or other cnidarian) which is attached to a substrate. Tumour projecting from mucosal surface.... polyp

1 The administration of many drugs at the same time. 2 The administration of an excessive number of drugs.... polypharmacy

A molecule in which several AMINO ACIDS are joined together by peptide bonds. PROTEIN molecules are polypeptides.... polypeptide

The presence of a crop, or large number, of polypi (see POLYPUS). The most important form of polyposis is that known as familial polyposis coli. This is a hereditary disease characterised by the presence of large numbers of polypoid tumours in the large bowel. Every child born to an affected parent stands a ?fty-?fty chance of developing the disease. Its importance is that sooner or later one or more of these tumours undergoes cancerous change. If the affected gut is removed surgically before this occurs, and preferably before the age of 20, the results are excellent.... polyposis

or polyp (plural: polypi). A general name applied to tumours which are attached by a stalk to the surface from which they spring. The term refers only to the shape of the growth and has nothing to do with its structure or nature. Most polypi are of a simple nature, although malignant polypi are also found. The usual structure of a polypus is that of a ?ne ?brous core covered with epithelium resembling that of the surrounding surface. The sites in which polypi are most usually found are the interior of the nose, the outer meatus of the ear, and the interior of the womb, bladder, or bowels (see POLYPOSIS).

Their removal is generally easy, as they are simply twisted o?, or cut o?, by some form of snare or ligature. (The tissue removed should be checked for malignant cells.) Those which are situated in the interior of the bladder or bowels, and whose presence is usually recognised because blood appears in the urine or stools, require a more serious operation – usually an endoscopic examination (see ENDOSCOPE).... polypus

Linn.

Family: Liliaceae.

Habitat: Native to East Africa and Saudi Arabia.

English: Dragon's Blood.

Ayurvedic: Khoonkharaabaa, Heeraadokhi.

Unani: Dammul-Akhwain.

Family: Araceae.

Habitat: Maharashtra and Karnata- ka; cultivated in the South.

Siddha/Tamil: Kattu Karunayikki- langu.

Folk: Jangali Suuran.

Action: Root—antidiarrhoeal, anti-inflammatory (prescribed for haemorrhoids), antispasmodic (used in asthma), emmenagogue, abortifacient.... dracontium polyphyllum

Previously called juvenile rheumatoid arthritis and juvenile chronic arthritis, this is a set of related conditions of unknown cause affecting children. Characteristically, the synovial membrane of a joint or joints becomes in?amed and swollen for at leat six weeks (and often very much longer – even years). About 1 in 10,000 children develop it each year, many of whom have certain HLA genetic markers, thought to be important in determining who gets the illness. In?ammatory CYTOKINES play a big part.

Clinical features There are various types. The oligoarthritic type involves 1–4 joints (usually knee or ankle) which become hot, swollen and painful. One complication is an in?ammation of the eyes – UVEITIS. The condition often ‘burns out’, but may reappear at any time, even years later.

The polyarthritic type is more like RHEUMATOID ARTHRITIS in adults, and the child may have persistent symptoms leading to major joint deformity and crippling.

The systemic type, previously called Still’s disease, presents with a high fever and rash, enlarged liver, spleen and lymph nodes, and arthritis – although the latter may be mild. In some children the illness becomes recurrent; in others it dies down only to return as polyarthritis.

Complications These include uveitis, which can lead to loss of vision; a failure to thrive; osteoporosis (see under BONE, DISORDERS OF); joint deformity; and psychosocial diffculties.

Treatment This includes ANTIPYRETICS and ANALGESICS, including NON-STEROIDAL ANTIINFLAMMATORY DRUGS (NSAIDS), intra-articular steroid injections, anti-tumour necrosis factor drugs and steroids.

Physiotherapy is vital, and children may need to wear splints or other orthotic devices to alleviate deformity and pain. Orthopaedic operative procedures may be necessary.... juvenile idiopathic arthritis (jia)

D. Don.

Family: Liliaceae.

Habitat: Uttaranchal, Himachal Pradesh.

Ayurvedic: Kaakoli, Madhuraa, Kshira, Vayhasthaa, Karnikaa, Vaayasoli.

Action: Tuberous root—used as a tonic in emaciation and as a source of energy, after dry roasting.

Dosage: Tuberous root—3-6 g. (API, Vol. III.)... lilium polyphyllum

Sm.

Family: Liliaceae.

Habitat: Temperate Himalayas from Simla to Bhutan and in Lushai and Aka Hills. Haimavati, Shveta-

Action: Plant—sedative, analgesic, haemostatic, anthelmintic.

The rhizome contains a glucoside, alpha-paristyphnin, which exhibited a depressant action on carotid pressure, myocardium, and respiratory movements experimentally. It produced vasoconstriction in kidney, but vasodilation in the spleen and limbs, and stimulated isolated intestines.... paris polyphylla

A suggestion by two epidemiologists, made in the British Medical Journal in 2003, that many lives could be saved if all persons aged over 55 took a daily combination pill they termed the polypill. Its components would be ASPIRIN, a CHOLESTEROL-lowering agent, FOLIC ACID and two blood-pressure-lowering agents. The suggestion caused a massive correspondence as it implied treating a whole population rather than individuals considered to be at special risk.... polypill

Linn.

Family: Polypodiaceae. English: Polypody Root. Unani: Bisfaayaj.

Action: Expectorant, laxative, stomachic, cholagogue, alterative, antistress. Used in cough, bronchitis, catarrh, loss of appetite, dyspepsia; and in skin diseases.

The rhizome gave saponin glyco- sides, based on polypodosapogenin, including osladin; ecdysteroids; phlo- roglucin derivatives; tannin.... polypodium vulgare

Fries

Family: Polyporaceae.

Habitat: On the old trunks of various coniferous trees.

English: White Agaric.

Unani: Ghaariqoon.

Action: Used in the treatment of sweats in wasting diseases such as phthisis (it checks profuse sweats); also as an expectorant and diuretic.

The drug contains agaric acid (agari- cin). The resinous extract, when burnt, yields not more than 2% of a white ash, rich in phosphates. The drug gives 46% soft resin.

Agaric acid acts as a counter-irritant when applied to abraded surfaces or mucous membrane.... polyporus officinalis

A group of rheumatoid conditions of unknown causation with onset before 16 years. Girls more than boys. Still’s disease being the form presenting with enlargement of spleen and lymph nodes, high temperature with macular rash comes and goes. Children usually ‘grow out of it’ although stiffness may continue. Deformities possible. Tardy bone growth of the mandibles giving the face a birdlike look. May progress to rheumatoid arthritis (girls) or ankylosing spondylitis (boys). So strong is psychosomatic evidence that sociologists believe it to be a sequel to broken families, divorce or bereavement. Few patients appear to come from a balanced environment or happy home.

Treatment. BHP (1983) recommends: Meadowsweet, Balm of Gilead, Poke root, Bogbean, Hart’s Tongue fern, Mountain Grape.

Teas: Singly or in combination (equal parts): Chamomile, Bogbean, Nettles, Yarrow. 1-2 teaspoons to each cup boiling water; infuse 5-10 minutes. 1 cup thrice daily before meals.

Tablets/capsules. Blue Flag root, Dandelion root, Poke root, Prickly Ash bark.

Formula. White Poplar bark 2; Black Cohosh half; Poke root quarter; Valerian quarter; Liquorice quarter. Mix. Dose: Powders: 500mg (two 00 capsules or one-third teaspoon) (children 5-12 years: 250mg – one 00 capsule or one-sixth teaspoon). Liquid extracts: 1 teaspoon: (children 5-12: 3-10 drops). Tinctures: 2 teaspoons: (children 5-12: 5-20 drops).

Evening Primrose oil. Immune enhancer.

Topical. Hot poultice: Slippery Elm, Mullein or Lobelia.

Diet: Lacto vegetarian. Kelp. Comfrey tea. Molasses. Low fat.

General. Adequate rest, good nursing, gentle manipulation but no massage to inflamed joints. Natural lifestyle. Parental emotional support.

Oily fish. See entry. ... arthritis, juvenile, chronic

See juvenile chronic arthritis.... juvenile arthritis

A rare form of arthritis affecting children. Juvenile chronic arthritis occurs more often in girls, and usually develops between 2 and 4 years of age or around puberty. There are 3 main types. Still’s disease (systemic onset juvenile arthritis) starts with fever, rash, enlarged lymph nodes, abdominal pain, and weight loss. These symptoms last for a period of several weeks. Joint pain, swelling, and stiffness may develop after several months. Polyarticular juvenile arthritis causes pain, swelling, and stiffness in many joints. Pauciarticular juvenile arthritis affects 4 joints or fewer.

Possible complications include short stature, anaemia, pleurisy, pericarditis, and enlargement of the liver and spleen. Uveitis may develop, which, if untreated, may damage vision. Rarely, amyloidosis may occur or kidney failure may develop. Diagnosis is based on the symptoms, together with the results of X-rays and blood tests, and is only made if the condition lasts for longer than 3 months.

Treatment may include antirheumatic drugs, corticosteroid drugs, nonsteroidal anti-inflammatory drugs, or aspirin. Splints may be worn to rest inflamed joints and to reduce the risk of deformities. Physiotherapy reduces the risk of muscle wasting and deformities.

The arthritis usually clears up after several years. However, in some children, the condition remains active into adult life.

– kala-azar A form of leishmaniasis that is spread by insects. Kala-azar occurs in parts of Africa, India, the Mediterranean, and South America.... juvenile chronic arthritis

A raised, reddishbrown skin blemish which sometimes appears on the face or legs in early childhood (see naevus). Although they are usually harmless, an unsightly growth,or one suspected of being skin cancer, can be removed surgically.... melanoma, juvenile

A growth in the lining of the nose, usually attached by a small stalk.

Most nasal polyps are noncancerous, but they may need to be removed if they cause nasal obstruction.... nasal polyp

(FAP) see polyposis.... familial adenomatous polyposis

a fibrous overgrowth covered by epithelium, often occurring inside the mouth in response to chronic irritation (usually following accidental biting). It is sometimes called a fibrous *epulis.... fibroepithelial polyp

see juvenile idiopathic arthritis.... juvenile-onset spondylarthropathy

A rare, inherited disorder, also known as polyposis coli, in which many polyps are present throughout the gut, but mainly in the colon. If not treated, cancer of the colon (see colon, cancer of) is almost certain to develop. The polyps may appear from age 10. They may cause bleeding and diarrhoea; however, there are often no symptoms until cancer has developed. The polyps are detected by colonoscopy.

Since there is a 50 per cent chance that children of an affected person will inherit the disease, medical surveillance is necessary from around the age of 12.

Individual polyps may be cauterized (see cauterization).

The high risk of developing cancer often means that a colectomy and an ileostomy are performed.... polyposis, familial

(JIA, Still’s disease) any one of a group of conditions characterized by inflammation of the joints lasting longer than 6 weeks and occurring before the age of 16. The causes are unknown but immunological and infective mechanisms are suspected. JIA can affect either four or fewer joints (pauciarticular JIA) or more than four (polyarticular JIA). There are two recognized types of pauciarticular JIA: type 1, which generally affects girls below the age of four; and type 2 (juvenile-onset spondylarthropathy), which generally affects boys over the age of nine. There are also two types of polyarticular JIA, depending on the presence or absence of a particular antibody in the blood. There is a great range of severity of these diseases. Treatment consists of pain management and prevention of subsequent deformity or limitation of movement (e.g. contractures). Long-term joint damage is prevented by use of medications similar to those used in rheumatoid arthritis.... juvenile idiopathic arthritis

see dermatosis.... juvenile plantar dermatosis

a hormone released from the D cells of the *islets of Langerhans of the pancreas in response to protein in the small intestine. Its actions are to inhibit pancreatic bicarbonate and protein enzyme secretion and to relax the gall bladder. It belongs to a family of similar hormones that have actions on appetite and food metabolism.... pancreatic polypeptide

n. the endoscopic or surgical removal of a *polyp. The technique used depends upon the site and size of the polyp. Endoscopically, polyps can be removed by various methods. A hot biopsy involves coagulation of a small polyp using a diathermy current passed through biopsy forceps, which obtains a sample for analysis at the same time. Cold biopsy involves removal of a polyp using forceps alone, thereby decreasing the perforation risk. Snare polypectomy uses a wire loop (snare) to cut through the base of the polyp. This is performed with or without a diathermy current (hot snare vs. cold snare); the current reduces the risk of bleeding by coagulating local blood vessels as the snare cuts through the polyp. Endoscopic mucosal resection (EMR) involves lifting a flat polyp by injecting a hypertonic solution into the submucosa beneath the polyp followed by snare polypectomy with diathermy. Nasal polyps may be removed using *endoscopic sinus surgery techniques, sometimes utilizing a *microdebrider.... polypectomy

n. excessive eating.... polyphagia

adj. describing a number of individuals, species, etc., that have evolved from more than one ancestral group. Compare monophyletic.... polyphyletic

adj. describing cells, tissues, or individuals in which there are three or more complete sets of chromosomes. Compare diploid; haploid. —polyploidy n.... polyploid

adj. having the appearance of a *polyp.... polypoid