Kashmir Health Dictionary

Kashmir: From 1 Different Sources


(Sanskrit) From the state in India Kashmira, Kasha, Kashmeer, Kazmir, Kazmira, Kazmeer, Kazhmir
Health Source: Medical Dictionary
Author: Health Dictionary

Nagadanti

Baliospermum montanum

Euphorbiaceae

San: Danti;

Hin: Danti;

Mal: Danti, Nagadanti;

Tam: Nakatanti;

Tel: Nelajidi

Importance: Danti or Nagadanti is a stout undershrub with numerous flowers. Root, which is the officinal part, is used in abdominal pain, constipation, calculus, general anasarca, piles, helminthic manifestations, scabies, skin disorders, suppurative ulcers and diseases caused by the morbidity of kapha and pitta. Root paste is applied to painful swellings and piles. Leaves cure asthma and seeds are used in snakebite (Kurup et al, 1979; Sharma, 1983). The drug forms an important constituent of preparations like Dantyarishta, Dantiharitakileham, Kaisoraguggulu gulika, etc.(Sivarajan et al, 1994).

Distribution: The plant is found throughout the sub-Himalayan tracts from Kashmir to Khasi Hills. It is common in West Bengal, Bihar and Central and Peninsular India.

Botany: Baliospermum montanum (Willd.) Muell-Arg. syn. B. axillare Bl., B. polyandrum Wt. belongs to the family Euphrobiaceae. It is a stout under-shrub 0.9-1.8m in height with herbaceous branches from the roots. Leaves are simple, sinuate-toothed, upper ones small, lower ones large and sometimes palmately 3-5 lobed. Flowers are numerous, arranged in axillary racemes with male flowers above and a few females below. Fruits are capsules, 8-13mm long and obovoid. Seeds are ellipsoid smooth and mottled (Warrier et al,1993).

Agrotechnology: The tropical plant is suited to almost all soils. It can be cultivated either as pure crop or intercrop. It is propagated vegetatively by cuttings. About 15-20cm long rooted cuttings are used for planting. Pits of size 50cm cube are to be taken at 3m spacing and filled with dried cowdung, sand and top soil and formed into a mound. On these mounds, rooted cuttings are to be planted at 2 cuttings/mound. Cuttings establish within one month. Weeding is to be carried out at this time. Application of organic manure after every 6 months is beneficial. Irrigation during summer months is preferable. The plant is not attacked by any serious pests or diseases. Roots can be collected at the end of second year. The roots are to be cut and dried in sun before marketing. The yield is about one tonne root/ha (Prasad et al,1997).

Properties and activity: Roots contain diterpenes, baliospermin, montanin, phorbol-12-deoxy-13-O-palmitate, phorbol-12-deoxy-16-hydroxy-13-O-palmitate and phorbol-12-deoxy-5 -hydroxy-13 – myristate (Ogura et al, 1978). Alcoholic extract of plant showed hypotensive activity in experimental animals (Bhakuni et al, 1971). Antilukaemic and cytotoxic activities have been demonstrated in the esters of both 12-deoxyphorbol and 12-deoxy-16-hydroxyphorbol, isolated from B. montanum (King-horn, 1979). The roots are acrid, thermogenic, purgative, antiinflammatory, anodyne, digestive, anthelmintic, diuretic, diaphoretic, rubefacient, febrifuge and tonic. Seed is purgative, stimulant, rubefacient and antidote for snakebite. Seed oil is antirheumatic. Leaf is antiasthmatic and wound healing. Root and seed oil is cathartic and antidropsical. Stem is anti-dontalgic.... nagadanti

Abies Pindrow

Royle.

Synonym: A. pindrow Spach. A. webbiana Lindl. var. pindrow Brandis. Pinus pindrow Royle.

Family: Pinaceae.

Habitat: Kashmir, Himachal Pradesh, Tehri-Garhwal and other areas of northern India, at altitudes of 2,100-3,600 m.

English: Pindrow-Fir, Silver-Fir, The West-Himalayan Low-Level Fir.

Ayurvedic: Taalisha (related sp.).

Folk: Badar, Morinda, Raisalla, Ransla.

Action: Uses similar to those of A. webbiana.

Terpenoids, flavonoids, glycosides and steroids of the leaf were found to have mast cell stabilizing action in rats. Terpenoids and flavonoids offered bronchoprotection against his- tamine challenge in guinea pigs. The ulcer protective action of petroleum ether, benzene and chloroform fraction has been attributed to steroidal contents. Terephthalic acid demethyl ester (TADE), isolated from the leaf, exhibited protection against inflammation and bronchospasm in guinea pigs. Ethanolic extract of leaves showed significant anxiolytic effects on all the paradigms of anxiety, barbiturate hypnosis potentiation.

Pindrolactone, a lanostane-based triterpene lactone, isolated from the leaves, showed mild activity against Gram-positive bacteria but exhibited potent antibacterial activity against Gram-negative bacteria E. coli.... abies pindrow

Abies Webbiana

Lindl.

Synonym: A. spectabilis (D. Don) Spach.

Pinus webbiana Wall.

Family: Pinaceae.

Habitat: The Himalayas from Kashmir to Assam at altitudes of 1,600-4,000 m.

English: Indian Silver Fir, The West-Himalayan High-Level Fir, The East-Himalayan Fir.

Ayurvedic: Taalisa, Taalisapatra, Taalisha, Patraadhya, Dhaatriparni, Dhaatripatra.

Unani: Taalisapattar.

Siddha/Tamil: Taalispatri.

Folk: Badar, Chilrow, Morinda, Raisalla, Taalispatra. (Tallispatra, Taalispatri and Talespattre are also equated with the leaves of Cinnamomum tamala Nees.)

Action: Expectorant, bronchial sedative, decongestant, anticatarrhal, antiseptic, carminative.

Key application: Fir (Abies alba Miller) needle oil—in catarrhal illness of upper and lower respiratory tract (internally and externally); externally in rheumatic and neuralgic pains. Contraindicated in bronchial asthma and whooping cough. (German Commission E.)

A biflavonoid, abiesin, n-triaconta- nol, beta-sitosterol and betuloside are present in the leaves.

The essential oil from leaves contains alpha-pinene, l-limonene, delta- carene, dipentene, l-bornyl acetate and l-cardinene as major constituents.

Dosage: Needles—2-6 g powder. (API Vol. IV.)... abies webbiana

Achillea Millefolium

Linn.

Synonym: A. lanulosa Nutt.

Family: Compositae; Asteraceae.

Habitat: The western Himalayas from Kashmir to Kumaon.

English: Milfoil, Yarrow, Thousand Leaf.

Unani: Biranjaasif. National Formulary of Unani Medicine also equates Leonurus cardica Linn. (Labiatae) with Biranjaasif.

Folk: Gandana, Rojmari.

Action: Anti-inflammatory, anti- spasmodic (used in cold, flatulent colic, heartburn), emmenagogue, cicatrizant, antidysenteric, anti- haemorrhagic, antipyretic, diaphoretic, diuretic, urinary antiseptic.

Key application: In dyspeptic ailments, such as mild, spastic discomforts of the gastrointestinal tract. As astringent, antispasmodic, choleretic, antibacterial. (German Commission E.) As diaphoretic. (The British Herbal Pharmacopoeia.) Internally for feverish conditions, common cold and digestive complaints; topically for slow-healing wounds and skin inflammations. (The British Herbal Compendium.)

The plant contains flavonoids, alkaloids (achilleine), polyacetylenes, triterpenes, coumarins, tannins, salicylic acid, a volatile oil containing linalool, camphor, sabinene, chamazu- lene and other azulenes.

Sesquiterpene lactones are bitter and tonic. Achilleine helps arrest internal and external bleeding. Flavonoids contribute to the antispasmodic action.

The flavonoid apigenin is anti-inflammatory, antiplatelet and spasmolytic. Alkaloids and bases are anti- inflammatory. Alkaloid betoncine is haemostatic. Salicylic acid is anti- inflammatory. Chamazulene is anti- inflammatory and antiallergenic. (Natural Medicines Comprehensive Database, 2007.)

An extract of the plant was found to be rich in luteolin or luteolin 7- glucoside and can be used for the treatment of hyperpigmentation of skin.... achillea millefolium

Ainsliaea Aptera

DC.

Family: Compositae; Asteraceae.

Habitat: The Himalayas from Kashmir to Bhutan at altitudes of 2,400 m, extending to Khasi hills of Meghalaya.

Folk: Karui Buuti (Garhwal).

Action: Powdered roots—used for quick relief from acute stomach ache; diuretic.

A related sp., A. latifolia Sch-Bip., is used as an adulterant to Podophyllum emodi.... ainsliaea aptera

Amphicome Emodi

Lindl.

Family: Bignoniaceae.

Habitat: Temperate Himalaya from Kashmir to Kumaon at 600-2700 m.

Folk: Kaur (Kashmir).

Action: Plant—febrifuge; used as a substitute for Swertia chirayita.

An iridoid glycoside named amph- icoside is reported from the plant.... amphicome emodi

Aconitum Chasmanthum

Stapf ex Holmes.

Family: Ranunculaceae.

Habitat: The western Himalayas from Hazara to Kashmir and Chamba in Himachal Pradesh, between altitudes of 2,100 m and 3,600 m.

English: Indian Napellus.

Ayurvedic: Visha, Shringika-Visha, Vatsanaabha (related sp.).

Folk: Mohri, Meethaa Zahar.

Action: Sedative, antirheumatic, analgesic, antitussive, antidiar- rhoeal. Ayurvedic Formulary of India, Part I and Part II, equated A. chasmanthum with Vatsanaabha. (See A.ferox.) It has the same uses as A. ferox. The alkaloid content of the root ranges from 2.98 to 3.11%; includes chasmaconitine and chasmanthinine.

Napellus, equated with Aconitum napellus Linn., is indigenous to Central Europe (named after the Black sea port Aconis and known as Wolfsbane, Monkshood). Aconitum of homoeopathic medicine is an alkaloid obtained from the roots and stems of A. nepellus. Used as an analgesic and sedative. It contains terpenoids up to 1.2%, including aconitine and aconine.

Toxic constituents of A. napellus are aconitine, mesaconitine, hypaconi- tine, 3-acetylacoitine, lappaconitine (diterpenoid-ester alkaloids), benza- conine, benzoylaconine.

Aconitine, mesaconitine and hyp- aconitine exert widespread effects on cardiac, neural and muscle tissue by activitating sodium channels. (Natural Medicines Comprehensive Database, 2007.)

Aconitine is absorbed through mucus membranes and the skin. (Francis Brinker.) It is a cardiotoxin and interacts with antiarrhythmics, antihypertensives, Digoxin/cardiac glycosides. (Sharon M. Herr.)

Dosage: Root—10-15 mg powder. (CCRAS.)... aconitum chasmanthum

Aconitum Deinorrhizum

Stapf.

Family: Ranunculaceae.

Habitat: Alpine regions of Chat- tadhar and Bhalesh ranges of Bhadarwah district in Jammu and Kashmir.

Ayurvedic: Vatsanaabha (related sp.).

Folk: Bashahr-Mohra, Dudhiyaa Bish, Safed Bikh.

Action: Roots and leaves are used in rheumatism, rheumatic fever and acute headache.

The roots contain 0.9% total alkaloids, of which 0.51% is pseudoaconi- tine.... aconitum deinorrhizum

Adiantum Capillus-veneris

Linn.

Family: Adiantaceae.

Habitat: All along the Himalayas from Kashmir to Sikkim between altitudes of 1,800 and 2,700 m.

English: American Maidenhair Fern, Venus Hair, Rock Fern.

Ayurvedic: Hansaraaja, Hansapadi (related sp.).

Unani: Parsiaavashaan.

Siddha/Tamil: Seruppadai.

Folk: Mubaaraka.

Action: Astringent, demulcent, expectorant, antitussive, stimulant, emmenagogue. Fonds used in chronic catarrh (as an ingredient of cough and bronchial medicines); also in cold imposthumes of uterus, hard swellings and hard tumours of spleen, liver and other viscera.

The fern contains flavonoid gluco- sides, including rutin, isoquercetin, as- tragalin, kaempferol; hydroxycinnam- ic acid esters; terpenoids, including adiantone.... adiantum capillus-veneris

Aesculus Indica

Hook.

Family: Sapindaceae; Hippocastana- ceae.

Habitat: The Himalayas from Kashmir to western Nepal, Kulu and Chamba in Himachal Pradesh, Tehri-Garhwal and Kumaon in Uttar Pradesh at 900-3,600 m.

English: Indian Horse Chestnut, Himalayan Chestnut.

Folk: Bankhor.

Action: Antirheumatic, galacto- genic, antileucorrhocic.

The leaves contain aescin, quercetin and beta-sitosterol. Stems also contain rutin, astragalin, aesculin. Seeds contain aescin, aesculuside A and B, also aliphatic esters. Seeds possess anti- inflammatory activity.

The extract of seeds is considered to be active against P-388 lymphocy- tic leukaemia and human epidermoid carcinoma of nasopharynx.... aesculus indica

Astragalus Strobiliferus

Royle.

Family: Fabaceae; Papilionaceae.

Habitat: The western Himalayas at 2,400-3,900 m, and Kashmir.

English: Indian Gum tragacanth.

Action: Gum—an Indian substitute for tragacanth (A. gummifer gum).... astragalus strobiliferus

Balanophora Involucrata

Hook. f.

Family: Balanophoraceae.

Habitat: The Himalayas from Kashmir to Sikkim and Darjeeling at altitudes of 1,800-3,400 m

Ayurvedic: Chavya (tentative synonym).

Action: Astringent. Used in piles, also in rheumatism.

A related species, B.polyandra Griff., found in Nagaland, Manipur, West Bengal, Bihar, Orissa and Andhra Pradesh at 2,000 m, gave a phenolic gly- coside, coniferin. The plant is used as an antiasthmatic.... balanophora involucrata

Delphinium Cashmirianum

Royle.

Family: Ranunculaceae.

Habitat: Kashmir (Himalayan species).

English: Kashmir Larkspur.

Ayurvedic: Used as a substitute for Tagara (valerian).

Action: See D. brunonianum.... delphinium cashmirianum

Agrimonia Eupatoria

auct non L.

Synonym: A. pilosa Hook.f. non Ledeb.

A. pilosa Ledeb. var. nepalensis (D. Don) Nakai

Family: Rosacae.

Habitat: The Himalayas from Kashmir to West Bengal at 9003,000 m, and in Arunachal Pradesh, Nagaland and Meghalaya.

English: Agrimony, Stickle Wort.

Unani: Ghaafis.

Folk: Belu.

Action: Astringent, anti- inflammatory, hepatic, cholagogue, diuretic, mild haemostatic, antibacterial. Used for irritations and infections of the intestinal tract, gallbladder diseases, hyperacidity, colic, urinary disorders (bed- wetting, incontinence), sluggish liver, mucus membrane inflammations; externally for ulcerated and discharging skin, psoriasis and seborrhoic eczemas.

Key application: In mild, nonspecific, acute diarrhoea and in inflammation of oral and pharyngeal mucosa; as astringent. (German Commission E, The British Herbal Pharmacopoeia.)

The herb contains condensed tannins up to 8%, coumarins, flavonoids (glucosides of luteolin, apigenin and quercetin), polysaccharides, volatile oil. Luteolin 7-glucoside shows a chole- gogic action. Aqueous extracts inhibited Mycobacterium tuberculosis, also strains resistant to streptomycin and p-aminosalicylate. Essential oil is antibacterial, active against Bacillus sub- tilis.

The ethanolic extracts of the herb are used for their antiviral properties. (Natural Medicines Comprehensive Database, 2007.)

Coumarins interact with anticoagulants, and drugs that increase the risk of bleeding Furanocoumarin content increase photosensitivity. (Sharon M. Herr.)... agrimonia eupatoria

Agropyron Repens

Beauv.

Synonym: Triticum repens L.

Family: Gramineae; Poaceae.

Habitat: The western Himalayas and Kashmir at altitudes between 2,700 and 3,600 m.

English: Couch grass, dog grass, wheat grass.

Action: Demulcent (used in cystitis, nephritis), aperient, diuretic and urinary antiseptic, anticholesterolaemic.

Key application: In irrigation therapy for inflammatory diseases of the urinary tract and for the prevention of kidney gravel. (German Commission E, The British Herbal Pharmacopoeia.) It is contraindicated in oedema due to cardiac or renal insufficiency.

The juice of rhizomes is used for cystitis, nephritis, scirrhous liver; decoction for tonsils and as an adjuvant for cancer; also used for gout and rheumatism, and chronic skin disorders.

The rhizome contains triticin, a carbohydrate allied to starch, a fruc- tosan polysaccharide, inositol, manni- tol; volatile oil up to about 0.05%, consisting mainly of agropyrene; vanillin glucoside; mucilage, gum, large quantities of silica; iron, minerals, vitamins, K salt. Agropyrene is reported to have broad antibiotic properties. Extracts show uric acid solvent properties. Agropyrene is antifungal.... agropyron repens

Alkanna Tinctoria

(L.) Tausch.

Family: Boraginaceae.

Habitat: Cultivated in Central and southern Europe.

English: Alkanet, Dyers' or Spanish Bugloss.

Unani: Ratanjot. National Formulary of Unani Medicine equated Ratanjot with Onosma echioides Linn., found in Kashmir and Kumaon.

Siddha/Tamil: Ratthapaalai, Surul- pattai, Dineshavalli.

Action: Astringent, antimicrobial (used for indolent ulcers, wounds, erysipelas).

The root contains up to 5% alkan- nins, which are lipophilic isohexenyl- naphthazarin red pigments; tannins and wax. A pyrrolizidine (hepatotox- ic) alkaloid has also been isolated from the herb. The alkannins have antimicrobial and wound-healing properties and are non-toxic in mice. They have been used clinically for indolent ulcers.... alkanna tinctoria

Dianthus Carophyllus

Linn.

Family: Caryophyllaceae.

Habitat: Kashmir; commonly grown in gardens, especially on the hills.

English: Carnation, Clove Pink.

Action: Flowers—diaphoretic, alexiteric, cardiac tonic. whole plant—vermifuge. Juice of plant antiviral.

Leaves contain glucoproteins.

A related species, Dicentra anatoli- cus Boiss, found in the Western Himalayas, is used as an antiperiodic in intermittent fevers.... dianthus carophyllus

Doronicum Roylei

DC.

Family: Compositae; Asteraceae.

Habitat: The Western Himalayas from Kashmir to Garhwal.

Unani: Daarunaj Aqrabi Hindi.

Action: The root is reported to prevent giddiness caused during high attitude ascents.

The root yields a gum-resin, used in gargle water as stimulant, astringent and in toothpaste. Root—used in rheumatism. Leaves—carminative.... doronicum roylei

Eryngium Caeruleum

Bieb.

Family: Umbelliferae; Apiaceae.

Habitat: Kashmir and Western Himalayas.

Folk: Pahaari Gaajar, Dudhali (Punjab), Saleli-misri.

Action: Root—nervine, stimulant, haematinic, diuretic, diaphoretic, expectorant. Ash of the plant— antiseptic, anti-inflammatory (used in haemorrhoids).

Leaves and flowers contain d-man- nitol. Underground parts yield saponins.... eryngium caeruleum

Euphorbia Pilosa

Linn.

Family: Euphorbiaceae.

Habitat: Western Himalayas from Garhwal, westwards to Kashmir.

Ayurvedic: Saatala, Saptalaa. (Substitute).

Action: Purgative, emetic. Root— used in fistulous sores.

Prostratin, isolated from the roots of var. cornigeria Hook. f., was found to be pro-inflammatory.... euphorbia pilosa

Allium Porrum

Linn.

Synonym: A. ameloprasum Hook. f. non Linn.

Family: Liliaceae, Alliaceae.

Habitat: Native to the Mediterranean region; cultivated in India.

English: Leek.

Folk: Vilaayati Piyaaz. Praan (Kashmir). Seemevangayam (Tamil Nadu).

Action: Expectorant; used as a substitute for garlic.

Leek is poor in volatile oil content in comparison with garlic, but it contains sufficient amounts of non-toxic sapo- nins, which perhaps give it expectorant properties.

The bulbs contain several thiosul- phinates, and also potentially anticar- cinogenic flavonoids, quercetin and kaempferol.... allium porrum

Allium Schoenoprasum

Linn.

Family: Liliaceae, Alliaceae.

Habitat: Native to temperate northern Europe and the U.S.; distributed in the western Himalayas from Kashmir to Kumaon at altitudes of 2,400-3,000 m.

English: Chives.

Action: Used in place of young onions.

An alcoholic extract of the bulbs exhibited hypotensive and cardiac depressant activity.

The aerial parts (chives) gave alliins (alkylcysteine sulfoxides), particularly methyl alliin and pentylalliin.

Allium tuberosum Rottl. ex Spreng, found in eastern India and western Himalayas, is equated with Chinese Chives. It is available in Meghalaya.... allium schoenoprasum

Althaea Officinalis

Linn.

Family: Malvaceae.

Habitat: Native to eastern Europe; found in Kashmir and Himachal Pradesh.

English: Marshmallow, Hollyhock.

Unani: Khatmi, Gul-Khairu (also equated with Althaea rosea Linn.).

Siddha/Tamil: Shemai-tutti.

Action: Demulcent, emollient, antitussive (used for cough, bronchitis, gastritis, enteritis and cystitis), antilithic, diuretic.

Key application: (leaf and root) In irritation ofthe oral and pharyngeal mucosa and associated dry cough; in mild inflammation of the gastric mucosa. (German Commission E, ESCOP.) As demulcent. (The British Herbal Pharmacopoeia.) In gastroenteritis, peptic and duodenal ulceration, common and ulcerative colitis. (The British Herbal Compendium.) Topically for varicose veins, skin ulcers, abscesses, cuts, burns.

Althaea rosea (L.) Cav., synonym Al- cea rosea L., Hollyhock flower, is used as mucilage for prophylaxis and therapy of diseases and discomforts of the respiratory and gastrointestinal tract and for urinary complaints. (It is included among unapproved herbs by German Commission E.)

The root contains starch, mucilage, pectin, flavonoids, phenolic acids, sucrose, tannins and asparagines. Mucilage (18-35%) consists of a number of polysaccharides. Flavonoids include kaempferol, quercetin and diosmetin glucosides. Polyphenolic acids include syringic, caffeic, salcyclic, vanillic and p-coumaric acids.

The mucilages have proven biological activity including stimulation of phagocytosis in vitro.

The root counters excess stomach acid, peptic ulceration and gastritis.... althaea officinalis

Amygdalus Communis

Linn.

Synonym: Prunus amygdalus Baill. A. communis var. dulcis (sweet almond).

A. communis var. amara (bitter almond).

Family: Rosaceae.

Habitat: Native to Asia Minor and Persia; cultivated in India in cooler parts of Punjab and Kashmir.

English: Almond

Ayurvedic: Vaataama, Vaataada.

Unani: Badaam, Loz.

Siddha/Tamil: Vaadumai.

Action: Sweet almonds—nutrient, nervine tonic, demulcent. Oil— externally for skin. Bitter almonds— not used medicinally.

Almond flour and almond butter are free from starch and used in foods for diabetics and for patients with peptic ulcers. Chief protein in kernels is globulin.... amygdalus communis

Euphorbia Thomsoniana

Boiss.

Family: Euphorbiaceae.

Habitat: Kashmir, above 2,350 m.

Ayurvedic: Hiyaavali, Svarnakshiri (also equated with Argemone mexicana L., Papaveraceae.), Kanchanakshiri, Pitadugdhaa, Katuparni.

Folk: Hiravi (Kashmir). Titari (Himachal Pradesh).

Action: Root—purgative. Latex— used in eruptions and other skin diseases.... euphorbia thomsoniana

Fritillaria Imperialis

L.

Family: Liliaceae.

Habitat: Kashmir at 1,700-3,000 m.

English: Crown Imperial, Imperial Fritillary.

Action: Bulbs—emollient, diuretic, resolvent, spasmolytic, hypotensive, cardiotonic.... fritillaria imperialis

Laminum Amplexicaule

Linn.

Family: Labiatae; Lamiaceae.

Habitat: The temperate Himalayas from Kashmir to Kumaon, Sikkim and Assam.

Folk: Titpaati (Garhwal), Jipachi (Tibbet).

Action: Plant—stimulant, laxative, diaphoretic, cephalic, antirheum- atic.... laminum amplexicaule

Limnanthemum Nymphaeoides

Hoffm. & Link.

Synonym: Nymphoides peltata (Gmel.) O. Kuntze.

Family: Menyanthaceae.

Habitat: Kashmir.

English: Fringed Water-Lily.

Folk: Kuru, Khairposh (Punjab).

Action: Leaf—used in periodic headache.... limnanthemum nymphaeoides

Anagallis Arvensis

Linn.

Family: Primulaceae.

Habitat: Northwestern Himalayas from Kashmir eastwards to Nepal, hills of West Bengal; Central and southern India.

English: Bird's Eye, Bird's Tongue, Blue Pimpernel, Scarlet Pimpernel.

Unani: Anaaghaalis.

Folk: Jonkmaari (Maharashtra), Dhabbar (Punjab), Jighanaa, Jenghani.

Action: Plant—anti-inflammatory, astringent, deobstructant, an- tifungal, nematocidal; toxic to leeches.

The plant yields anagalligenone B. The presence of quaternary alkaloids, gluco-fructoside and tannin have been reported. The root yields glycosidic saponins, including cyclamin. An acetyl saponin, isolated from the plant, was found to possess marked taenici- dal activity but had no effect on round- worms.

A methanolic extract of the aerial parts showed activity against herpes simplex I, adenovirus type II and polio type II. Triterepene saponins have oestrogenic activity.... anagallis arvensis

Angelica Archangelica

Linn. var. himalaica (C. B. Clarke) Krishna and Badhwar

Family: Umbelliferae; Apiaceae.

Habitat: Native to Syria; now grown in Kashmir at 1,000-3,900 m.

Ayurvedic: Chandaa, Chandaam- shuka, Kathachoraa.

Action: Expectorant, carminative, digestant, cholagogue, antispas- modic, diaphoretic, diuretic, anti-inflammatory, smooth muscle relaxant, antifungal, antibacterial.

Key application: In flatulence and peptic discomforts. The root is a component in numerous gastrointestinal, cholagogue and biliary remedies in Germany. (Angelica root is an approved herb, whereas the seed and above-ground parts have been included among unapproved herbs by German Commission E.)

Chinese angelica root, Dong Quai, is equated with Angelica sinensis. It is prescribed internally for menstrual irregularity, lack of menstruation and painful menstruation.

The roots from Kashmir yield furo- coumarins, phenol compounds and flavonoids.

Xanthotoxol exhibited antihista- mintic and antinicotinic activities on guinea-pig ileum. The dry extract has been shown to have anti-inflammatory activity

The root is reported to inhibit bacterial and fungal growth.

Furocoumarins, especially psoralen and 8-methoxypsoralen, are used in the photochemotherapy of psoriasis and vitiligo. The biological activity is due to covalent linkage formed with DNA by irradiation with long- wavelength UV light.

Most of the coumarins have shown significant calcium antagonistic activity in vitro.

Angelicin, a resin, is stimulating to the lungs and skin. contraindicated in bleeding disorders, peptic ulcers and pregnancy. (Sharon M. Herr.)

Dosage: Root—1-3 g powder. (CCRAS.)... angelica archangelica

Angelica Glauca

Edgew.

Family: Umbelliferae; Apiaceae.

Habitat: Kashmir and Chamba in Himachal Pradesh, between 1,8003,700 m.

English: Angelica.

Ayurvedic: Choraka, Chorakaa, Kopanaa, Chorakaakhya, Nishaachara, Dhanhar, Taskara, Kshemaka.

Action: Root—cordial and stimulant, carminative (used in constipation), expectorant, diaphoretic.

The root contains furocoumarins, also dimeric, lingusticum lactone.

Dosage: Root—3-5 g powder. (CCRAS.)... angelica glauca

Arctium Lappa

Linn.

Family: Compositae; Asteraceae.

Habitat: Native to northern Europe; now found in western Himalayas, Kashmir and Simla.

English: Common or Great Burdock.

Folk: Phaggarmuul (Kashmir).

Action: Hypoglycaemic (plant extract caused reduction of blood sugar with an increase in carbohydrate tolerance). Roots—inhibitory of tumour growth, cardiac stimulant, diuretic, spasmolytic. Leaves and seeds—anticutaneous (used in psoriasis, seborrhoic eczema).

Key application: As dermatolog- ical agent. (The British Herbal Pharmacopoeia.)

Important constituents of Burdock roots are fatty acids, organic acids, phenolic acids, lignans, sesquiterpenes, tannin, inulin and mucilage.

Extracts of the fruit are reported to have hypoglycaemic activity in rats. Arctigenin (lignan) is a weak inhibitor of experimental tumour growth. The antimicrobial properties are due to polyacetylenes (of the root). The root exhibits antibiotic activity against Staphylococcus, and is used for fungal and bacterial infections. A flavonoid, arctiin, shows smooth muscle relaxant properties.... arctium lappa

Medicinal Yams

Dioscorea spp.

Dioscoreaceae

The growing need for steroidal drugs and the high cost of obtaining them from animal sources led to a widespread search for plant sources of steroidal sapogenins, which ultimately led to the most promising one. It is the largest genus of the family constituted by 600 species of predominantly twining herbs. Among the twining species, some species twine clockwise while others anti-clockwise (Miege, 1958). All the species are dioceous and rhizomatous. According to Coursey (1967), this genus is named in honour of the Greek physician Pedenios Dioscorides, the author of the classical Materia Medica Libri Quinque. Some of the species like D. alata and D. esculenta have been under cultivation for a long time for their edible tubers. There are about 15 species of this genus containing diosgenin. Some of them are the following (Chopra et al, 1980).

D. floribunda Mart. & Gal.

D. composita Hemsl; syn. D. macrostachya Benth.

D. deltoidea Wall. ex Griseb; syn. D. nepalensis Sweet ex Bernardi.

D. aculeata Linn. syn. D. esculenta

D. alata Linn. syn. D. atropurpurea Roxb.

D. Globosa Roxb; D. purpurea Roxb; D. rubella Roxb.

D. bulbifera Linn. syn. D. crispata Roxb.

D. pulchella Roxb.; D. sativa Thunb. Non Linn.

D. versicolor Buch. Ham. Ex Wall.

D. daemona Roxb. syn. D. hispida Dennst.

D. oppositifolia Linn.

D. pentaphylla Linn. syn. D. jacquemontii Hook. f.

D. triphylla Linn.

D. prazeri Prain & Burkil syn. D. clarkei Prain & Burkill

D. deltoidea Wall. var. sikkimensis Prain

D. sikkimensis Prain & Burkill

Among the above said species, D. floribunda, D. composita and D. deltoidea are widely grown for diosgenin production.

1. D. floribunda Mart. & Gal D. floribunda Mart. & Gal. is an introduction from central America and had wide adaptation as it is successfully grown in Karnataka, Assam, Meghalaya, Andaman and Goa. The vines are glabrous and left twining. The alternate leaves are borne on slender stems and have broadly ovate or triangular ovate, shallowly cordate, coriaceous lamina with 9 nerves. The petioles are 5-7cm long, thick and firm. Variegation in leaves occurs in varying degrees. The male flowers are solitary and rarely in pairs. Female flowers have divericate stigma which is bifid at apex. The capsule is obovate and seed is winged all round. The tubers are thick with yellow coloured flesh, branched and growing upto a depth of 30cm (Chadha et al, 1995).

2. D. composita Hemsl.

D. composita Hemsl. according to Knuth (1965) has the valid botanical name as D. macrostachya Benth. However, D. composita is widely used in published literature. It is a Central American introduction into Goa, Jammu, Bangalore, Anaimalai Hills of Tami Nadu and Darjeeling in W. Bengal. The vines are right twinning and nearly glabrous. The alternate leaves have long petioles, membraneous or coriaceous lamina measuring upto 20x18cm, abruptly acute or cuspidate-acuminate, shallowly or deeply cordate, 7-9 nerved. The fasciculate-glomerate inflorescence is single or branched with 2 or 3 sessile male flowers having fertile stamens. Male fascicle is 15-30cm long. The female flowers have bifid stigma. Tubers are large, white and deep-rooted (upto 45cm) (Chadha et al, 1995).

3. D. deltoidea Wall. ex. Griseb.

D. deltoidea Wall. ex. Griseb. is distributed throughout the Himalayas at altitudes of 1000-3000m extending over the states of Jammu-Kashmir, H. P, U. P, Sikkim and further into parts of W. Bengal. The glabrous and left twining stem bears alternate petiolate leaves. The petioles are 5-12 cm long. The lamina is 5-15cm long and 4-12cm wide widely cordate. The flowers are borne on axillary spikes, male spikes 8-40cm long and stamens 6. Female spikes are 15cm long, 3. 5cm broad and 4-6 seeded. Seeds are winged all round. Rhizomes are lodged in soil, superficial, horizontal, tuberous, digitate and chestnut brown in colour (Chadha et al, 1995). D. deltoidea tuber grows parallel to ground covered by small scale leaves and is described as rhizome. The tubers are morphologically cauline in structure with a ring of vascular bundles in young tubers which appear scattered in mature tubers (Purnima and Srivastava, 1988). Visible buds are present unlike in D. floribunda and D. composita where the buds are confined to the crown position (Selvaraj et al, 1972).

Importance of Diosgenin: Diosgenin is the most important sapogenin used as a starting material for synthesis of a number of steroidal drugs. For commercial purposes, its -isomer, yamogenin is also taken as diosgenin while analysing the sample for processing. Various steroidal drugs derived from diosgenin by artificial synthesis include corticosteroids, sex hormones, anabolic steroids and oral contraceptives. Corticosteroids are the most important group of steroidal drugs synthesized from diosgenin. First group of corticosteroids regulates carbohydrate and protein metabolism. The second group consists of aldosterone, which controls balance of potassium, sodium and water in the human body. The glucocorticoids in the form of cortisone and hydrocortisone are used orally, intramuscularly or topically for treatment of rheumatoid arthritis, rheumatic fever, other collegen diseases, ulcerative colitis, certain cases of asthma and a number of allergic diseases affecting skin, eye and the ear. These are also used for treatment of gout and a variety of inflammations of skin, eye and ear and as replacement therapy in Addison’s diseases. The minerato corticoides, desoxycorticosterone or desoxycortone are used in restoring kidney functions in cases of cortical deficiency and Addison’s disease.

Both male and female sex hormones are also synthesized from disosgenin. The main male sex hormone (androgen) which is produced from disogenin is testosterone. The main female sex hormones produced are oestrogen and progesterone. Recently oestrogen has also been used in cosmetic lotions and creams to improve the tone and colour of skin. One of the main uses of progesterone during recent years has been as antifertility agent for oral contraceptives. These artificial steroids have increased oral activity and fewer side effects, as they can be used in reduced doses. Oral contraceptives are also used for animals like pigs, cows and sheep to control fertility and to give birth at a prescribed period in a group of animals at the same time. These compounds are also used to reduce the interval between the lactation periods to have more milk and meat production. Anti-fertility compounds are also used as a pest-control measure for decreasing the multiplication of pests like rodents, pigeons and sea gulls (Husain et al, 1979).

Although yam tubers contain a variety of chemical substances including carbohydrates, proteins, alkaloids and tannins, the most important constituents of these yams are a group of saponins which yield sapogenins on hydrolysis. The most imp ortant sapogenin found in Dioscorea are diosgenin, yamogenin and pannogenin. Diosgenin is a steroid drug precursor. The diogenin content varies from 2-7% depending on the age of the tubers. Saponins including 5 spirastanol glucoside and 2 furostanol glucoside, 4 new steroid saponins, floribunda saponins C, D, E and F. Strain of A and B are obtained from D. floribunda (Husain et al, 1979). Rhizomes of D. deltoidea are a rich source of diosgenin and its glycoside. Epismilagenin and smilagenone have been isolated from D. deltoidea and D. prazeri (Chakravarti et al, 1960; 1962). An alkaloid dioscorine has been known to occur in D. hispida (Bhide et al,1978). Saponin of D. prazeri produced a fall of blood pressure when given intravenously and saponin of D. deltoidea has no effect on blood pressure (Chakravarti et al,1963). Deltonin, a steroidal glycoside, isolated from rhizomes of D. deltoidea showed contraceptive activity (Biokova et al, 1990).

Agrotechnology: Dioscorea species prefer a tropical climate without extremity in temperature. It is adapted to moderate to heavy rainfall area. Dioscorea plants can be grown in a variety of soils, but light soil is good, as harvesting of tubers is easier in such soils. The ideal soil pH is 5.5-6.5 but tolerates fairly wide variation in soil pH. Dioscorea can be propagated by tuber pieces, single node stem cuttings or seed. Commercial planting is normally established by tuber pieces only. Propagation through seed progeny is variable and it may take longer time to obtain tuber yields. IIHR, Bangalore has released two improved varieties, FB(c) -1, a vigorously growing strain relatively free from diseases and Arka Upkar, a high yielding clone. Three types of tuber pieces can be distinguished for propagation purpose, viz. (1) crown (2) median and (3) tip, of which crowns produce new shoots within 30 days and are therefore preferred. Dipping of tuber pieces for 5 minutes in 0.3% solution of Benlate followed by dusting the cut ends with 0.3% Benlate in talcum powder in mo ist sand beds effectively checks the tuber rot. The treatment is very essential for obtaining uniform stand of the crop. The best time of planting is the end of April so that new sprouts will grow vigorously during the rainy season commencing in June in India. Land is to be prepared thoroughly until a fine tilth is obtained. Deep furrows are made at 60cm distance with the help of a plough. The stored tuber pieces which are ready for planting is to be planted in furrows with 30cm between the plants for one year crop and 45cm between the plants for 2 year crop at about 0.5 cm below soil level. The new sprouts are to be staked immediately. After sprouting is complete, the plants are to be earthed up. Soil from the ridges may be used for earthing up so that the original furrows will become ridges and vice versa. Dioscorea requires high organic matter for good tuber formation. Besides a basal doze of 18-20t of FYM/ha, a complete fertilizer dose of 300kg N, 150kg P2O5 and K2O each are to be applied per hectare. P and K are to be applied in two equal doses one after the establishment of the crop during May-June and the other during vigorous growth period of the crop (August- September). Irrigation may be given at weekly intervals in the initial stage and afterwards at about 10 days interval. Dioscorea vines need support for their optimum growth and hence the vines are to be trailed over pandal system or trellis. Periodic hand weeding is essential for the first few months. Intercropping with legumes has been found to smother weeds and provide extra income. The major pests of Dioscorea are the aphids and red spider mites. Aphids occur more commonly on young seedlings and vines. Young leaves and vine tips eventually die if aphids are not controlled. Red spider mites attack the underside of the leaves at the base near the petiole. Severe infestations result in necrotic areas, which are often attacked by fungi. Both aphids and spider mites can be very easily controlled by Kelthane. No serious disease is reported to infect this crop. The tubers grow to about 25-30 cm depth and hence harvesting is to be done by manual labour. The best season for harvesting is Feb-March, coinciding with the dry period. On an average 50-60t/ha of fresh tubers can be obtained in 2 years duration. Diosgenin content tends to increase with age, 2.5% in first year and 3-3.5% in the second year. Hence, 2 year crop is economical (Kumar et al, 1997).... medicinal yams

Oxyria Digyna

(L.) Hill.

Family: Polygonaceae.

Habitat: The Himalayas from Kashmir to Sikkim, in the alpine region at altitudes of3,000-6,000 m.

Folk: Chohahak, Amlu (Punjab). Kailaashi (Kashmir).

Action: Refrigerant, antiscorbutic.... oxyria digyna

Physochlaina Praealta

Miers.

Family: Solanaceae.

Habitat: Lahul valley (Punjab), Ladakh, North Kashmir. Western Tibbet at altitudes of3,300-4,600 m.

Folk: Daturaa (Ladakh), Laangtaan; Sholar, Bajarbang (Punjab).

Action: Leaves—poisonous and narcotic.

The roots of the plant contain 0.64% alkaloids (calculated as hyoscyamine). The plant constitutes an excellent source of atropine.... physochlaina praealta

Arnebia Benthamii

(Wall. ex G. Don) Johnston.

Synonym: Macrotomia benthamii A. DC.

Family: Boraginaceae.

Habitat: The alpine Himalayas from Kashmir to Kumaon, at altitude of 3,000-3,900 m, and in Nepal.

Folk: Kashmiri Gaozabaan, Kashmiri Kahzabaan.

Action: Stimulant, cardiac tonic, expectorant, diuretic (syrup and jam, used in diseases of the mouth and throat, also in the treatment of fevers and debility.) The roots possess antiseptic and antibiotic properties.... arnebia benthamii

Artemisia Absinthium

Linn.

Synonym: Absinthium vulgare Gaertn.

A. officinale Lam.

Family: Compositae; Asteraceae.

Habitat: Kashmir at altitudes of 1500-2100 m.

English: Wormwood, Maderwood.

Unani: Afsanteen, Vilaayati Afsan- teen.

Siddha/Tamil: Machipatri.

Folk: Mastiyaaraa (Punjab), Titween (Kashmir).

Action: Choleretic (bile and gastric juice stimulant), anthelmintic, stomachic, carminative, antispasmodic, anti-inflammatory, emme- nagogue, mild antidepressant; used in chronic fevers.

Key application: In loss of appetite, dyspepsia, biliary dyskinesia. (German Commission E.) In anorexia, for example, after illness, and dyspeptic complaints. (ESCOP.) It is contraindicated in gastric and duodenal ulcers. Excessive doses may cause vomiting, severe diarrhoea, retention of urine or dazed feeling and central nervous system disturbances. (ESCOP.)

The herb contains a volatile oil of variable composition, with alpha- and beta-thujone as the major component, up to about 35%; sesquiterpene lactones (artabasin, absinthin, anab- sinthin); azulenes; flavonoids; phenolic acids; lignans.

Thujone is a toxic constituent which shows hallucinogenic and addictive activity found in Indian hemp. It stimulates the brain; safe in small doses, toxic in excess. The azulenes are anti- inflammatory. The sesquiterpene lac- tones exhibit an antitumour effect and are insecticidal and anthelmintic.

Essential oil from leaves—antibacterial, antifungal. The oil is toxic at 10 ml.... artemisia absinthium

Artemisia Maritima

Linn.

Family: Compositae; Asteraceae.

Habitat: The western Himalayas from Kashmir to Kumaon.

English: Wormseed, Santonica.

Ayurvedic: Chauhaara, Kirmaani Yavaani, Chuhaari Ajawaayin; not related to Ajawaayin.

Unani: Dirmanah, Kirmaalaa, Afsanteen-ul-bahar. (Dirmanah Turki is equated with A. stechmani- ana Besser.)

Folk: Kirmaani Ajawaayin, Kirmaani-owaa, Kirmaani-ajmo.

Action: Deobstructant, stomachic, anthelmintic (effective against roundworms), antifungal.

A decoction of the fresh plant is given in cases of intermittent and remittent fever.

A. maritima var. thomsoniana C. B. Clarke is a santonin-yielding var.; A. maritima var. fragrans (Willd.) Ledeb. is a non-santonin var.

Immature flowerheads and leaves contain santonin. Roots, stems and twigs are devoid of santonin. Santonin, a sesquiterpene lactone, is used for the treatment of ascaris and oxyuris infections. Large doses (0.3 g is adults and 0.06 in children) are toxic.

Beta-santonin is less anthelmintic in action than santonin; pseudosantonin is devoid of anthelmintic property.

Studies is albino mice revealed that santonin had no androgenic, estro- genic, antiestrogenic, progestational and antiprogestational effects.

Santonin is toxic at 60 mg in children; 200 mg in adults. (Francis Brinker.)

Dosage: Whole plant—3-6 g powder. (CCRAS.)... artemisia maritima

Polygonum Affine

D. Don.

Synonym: Bistorta affinis (D. Don) Green.

Family: Polygonaceae.

Habitat: Himalayas from Kashmir to Nepal at altitudes of 2,4004,800 m.

Folk: Khukhudi.

Action: Flowers—stimulant.

The inflorescence gave flavonoids, including quercetin, isorhamnetin, lu- teolin and apigenin derivatives. The leaves contain the flavonoids, 8-C- glucosyltricin and isorhamnetin.... polygonum affine

Prangos Pabularia

Lindl.

Family: Umbelliferae; Apiaceae.

Habitat: Kashmir and Himachal Pradesh at altitudes of 1,8004,000 m.... prangos pabularia

Pulicaria Dysenterica

Bernh.

Family: Asteraceae.

Habitat: Kashmir at 1,500-1,800 m.

Action: Plant—astringent, diuretic. Root—antidiarrhoeal. Leaf— antiasthmatic.... pulicaria dysenterica

Rosa Webbiana

Wall.

Family: Rosaceae.

Habitat: Dry and inner Himalayas from Kashmir to Kumaon at altitudes of 900-4,000 m.

Ayurvedic: Laddaakhi-Sevati. (Flowers— pink or deep red, fruit— red.)... rosa webbiana

Salix Viminalis

Linn. (The Himalayas from Kashmir to Sikkim) is known as Basket Willow and the Osier.

The bark contains 8.2%-8.8% tannin and phenol glycosides, fragilin, picein, salicin (0.13%), salicortin, salireposide, triandrin and vimalin. Salicase, and calcium and potassium nitrates are also reported from the bark.

Dosage: Bark—59-100 ml decoction. (CCRAS.)... salix viminalis

Arundo Donax

Linn.

Family: Gramineae; Poaceae.

Habitat: Native to Mediterranean region; found in Kashmir, Assam and the Nilgiris, also grown in hedges.

English: Great Reed, Spanish- Bamboo-Reed, Giant-Bamboo- Reed.

Ayurvedic: Nala, Potgala, Shuunya- madhya, Dhamana.

Siddha/Tamil: Korukkai.

Action: Rhizome—sudorific, emollient, diuretic, antilactant, antidropsical; uterine stimulant (stimulates menstrual discharge), hypotensive.

The rhizome yields indole-3-alkyl- amine bases, including bufotenidine and dehydro-bufontenine. The leaves yield sterols and triterpenoids.

Bufotenidine possesses antiacetyl- choline properties, histamine release activity and is a uterine stimulant. Alkaloids from the flowers produced cu- rarimetic effect of the non-polarizing type.

Dosage: Root—50-100 ml decoction. (CCRAS.) 4.5%) with methyl eugenol (an important constituent of A. europaeum), and also aristolochic acid. (Aristolochic acid is carcinogenic and nephrotoxic.) Asarum sp. are not used as a substitute for ginger.... arundo donax

Asclepias Curassavica

Linn.

Family: Aristolochiaceae.

Habitat: Indigenous to the northern parts of southern Europe, Central and East-Central Europe; cultivated in the United States. A related sp., Asarum himalaicum, synonym A. canadense, is reported from the eastern Himalayas.

English: Asarbacca, Hazelwort, Wild Nard.

Unani: Asaaroon, Subul-e-Barri, Naardeen-Barri.

Folk: Tagar Ganthodaa.

Action: Brain and nervine tonic, diuretic, deobstructant and anti- inflammatory; used in bronchial spasm and in preparations of cephalic snuffs.

The volatile oil (0.7-4%) consists of asarone up to 50%, asaraldehyde 2-3%, methyleugenol 15-20%, with bornyl acetate, terpenes and sesquiterpenes. Asarone and its beta-isomer is found to be carcinogenic in animals. The rhizome, in addition, contains caffeic acid derivatives and flavonoids.

A related sp., Asarum canadense L., indigenous to North America and China, contains a volatile oil (3.5-

Family: Asclepiadaceae.

Habitat: Naturalized in many parts of India as an ornamental.

English: Curassavian Swallow- Wort, West Indian Ipecacuanha, Blood-Flower.

Ayurvedic: Kaakanaasikaa (substitute).

Folk: Kaakatundi (Kashmir).

Action: Spasmogenic, cardiotonic, cytotoxic, antihaemorrhagic, styptic, antibacterial. Various plant parts, as also plant latex, are used against warts and cancer. Root—used as an astringent in piles. Leaves—juice, antidysenteric, also used against haemorrhages. Flowers—juice, styptic. Alcoholic extract of the plant—cardiotonic.

An alcoholic extract of the Indian plant has been reported to contain a number of cardenolides, including calactin, calotropin, calotropagenin, coroglaucigenin, uzarigenin, asclepin, its glucosides and uzarin. Asclepin, the chief active principle, is spasmogenic and a cardiac tonic, having longer duration of action than digoxin (96 h in cat, as opposed to the 72 h of digoxin). Calotropin exhibits cytotoxic activity.

Pleurisy root of the U.S. is equated with Asclepias tuberosa. It is used for cold, flu and bronchitis in Western herbal medicine.

Toxic principles of the herb include galitoxin and similar resins, and glu- cofrugoside (cardenolide). Toxicity is reduced by drying.... asclepias curassavica

Asplenium Adiantum-nigrum

Linn.

Family: Aspleniaceae.

Habitat: Kashmir at 1500-2000 m and extending to Dalhousie and Chamba in Himachal Pradesh.

English: Black Spleenwort.

Folk: Krishna fern.

Action: Fond—expectorant, pectoral, emmenagogue. Rhizome— anthelmintic. Plant—bitter, diuretic, laxative, anti-inflammatory. It is used for diseases of spleen and in jaundice; produces sterility in women.

The fonds contain aliphatic hydrocarbons, the chief one being hentri- acontane, non-acosane and triterpe- noid hydrocarbons, mainly of 22 (29)- hopene.

Alcohols, sterols and fatty acids are also reported.

Related sp. include: A. laciniatum D. Don (vitamin K3 and phthiocol have been isolated for the first time from the plant); A. adiantoides (L.) C. Chr., synonym A. falcatum Lam. (used in the treatment of enlarged spleen, in in- contenence of urine, in calculus, jaundice and malaria); A. nidus Linn. synonym Thamnopteris nidus (L.) C. Presl., known as Bird's Nest Fern (used as a depurative and sedative).... asplenium adiantum-nigrum

Salvia Lanata

Roxb.

Family: Labiatae; Lamiaceae.

Habitat: The temperate Himalayas from Kashmir to Nepal

Action: Roots—an adulterant of Saussurea lappa. Used as a substitute for Saliva moorcroftiana.... salvia lanata

Salvia Moorcroftiana

Wall. ex Benth.

Family: Labiatae; Lamiaceae.

Habitat: Northwestern Himalayas from Kashmir to Kumaon at 2,0003,000 m.

Folk: Kaali-jarri (Punjab).

Action: Root—bechic. Leaves— antitussive; applied as poultice to boils and chronic skin affections. Seeds—antispasmodic, emetic. Used for colic, dysentery, also for haemorrhoids; applied to boils.

The root gave a diterpene quinone.... salvia moorcroftiana

Saussurea Obvallata

Wall. ex C. B. Clarke.

Family: Compositae; Asteraceae.

Habitat: The Himalayas from Kashmir to Sikkim at 4,2005,000 m.

Folk: Brahma-kamal (Kumaon); Birm-kanwal (Punjab).

Action: Roots—antiseptic, styptic, anti-inflammatory. Applied to wounds and cuts.

Plant—hypothermic. Flower—CNS active, antiviral. The flowers, after frying, are used in rheumatism.... saussurea obvallata

Atropa Acuminata Royle Ex

Lindl.

Synonym: A. belladonna auct. non L.

Family: Solanaceae.

Habitat: Kashmir and Himachal Pradesh up to 2,500 m.

English: Indian Belladonna, Indian Atropa.

Ayurvedic: Suuchi.

Unani: Luffaah, Luffaah-Barri, Yabaruj, Shaabiraj.

Action: Highly poisonous; sedative, narcotic, anodyne, nervine, antispasmodic (used in paralysis); parkinsonism; encephalitis; carcinoma; spastic dysmenorrhoea; whooping cough, spasmodic asthma; colic of intestines, gall bladder or kidney, spasm of bladder and ureters; contraindicated in enlarged prostate.

Key application: In spasm and colic-like pain in the areas of the gastrointestinal tract and bile ducts. (German Commission E, The British Herbal Pharmacopoeia.) It is contraindicated in tachycardiac arrhythmias, prostate adenoma, glaucoma, acute oedema of lungs.

A. belladonna L. (European sp. Belladonna, Deadly Nightshade) is cultivated in Kashmir and Himachal Pradesh.

The herb contains tropane (tropine) or solanaceous alkaloids (up to 0.6%), including hyoscamine and atropine; flavonoids; coumarins; volatile bases (nicotine).

Tropane alkaloids inhibit the para- sympathetic nervous system, which controls involuntary bodily activities; reduces saliva, gastric, intestinal and bronchial secretions, and also the activity of urinary tubules. Tropane alkaloids also increase the heart rate and dilate the pupils. These alkaloids are used as an additive to compound formulations for bronchitis, asthma, whooping cough, gastrointestinal hy- permotility, dysmenorrhoea, nocturnal enuresis and fatigue syndrome.

Atropine provides relief in parkin- sonism and neurovegetative dystonia.

The root is the most poisonous, the leaves and flowers less, and the berries the least. (Francis Brinker.)

Dosage: Leaf, root—30-60 mg powder. (CCRAS.)... atropa acuminata royle ex

Berberis Chitria

Lindl.

Synonym: B. aristata auct. Hook. f & Thoms.

Family: Berberidaceae.

Habitat: The Himalayas from Kashmir to Nepal, at altitudes of 1,500-2,400 m.

Ayurvedic: Daaruharidraa (var.).

Folk: Totaro, Kintodaa (Garhwal).

Action: Same as that of Berberis aristata.

The root and stem bark contain alkaloids (5 and 4.2% respectively, calculated as berberine.)

The alcoholic extract of the roots was found to be better antimicrobial agent than the aqueous extract. The alkaloid palmitine hydroxide possesses an- tispermatogenic properties. See B. aristata and B. vulgaris. Berberis ulicina Hook, known as Khicharmaa in Tibet, is also equated with Daaruharidraa.... berberis chitria

Bergenia Ligulata

(Wall.) Engl.

Synonym: B. ciliata Sternb. Saxífraga ligulata Wall.

Family: Saxifragaceae.

Habitat: Temperate Himalaya from Kashmir to Bhutan, between altitudes of 900 and 3,000 m.

Ayurvedic: Paashaanabheda, Ashmaribhedikaa, Ashmaribhit, Ashmghna, Shilaabhit, Shilaabheda. (These synonyms are also equated with Aerva lanata Juss.)

Siddha/Tamil: Padanbethi.

Action: Leaf and root—antiscorbutic, astringent, spasmolytic, antidiarrhoeal. Used in dysuria, spleen enlargement, pulmonary affections as a cough remedy, menorrhagia, urinary tract infections. Alcoholic extract of roots— antilithic. Acetone extract of root- bark—cardiotoxic, CNS depressant and anti-inflammatory; in mild doses diuretic but antidiuretic in higher doses. Anti-inflammatory activity decreases with increasing dosage.

Due to its depressant action on the central nervous system, the drug is used against vertigo, dizziness and headache in moderate or low dosage.

Key application: In lithiasis, dysuria, polyuria. (The Ayurvedic Pharmacopoeia of India; Indian Herbal Pharmacopoeia.)

The rhizome contains an active principle bergenin (0.6%), gallic acid, glucose (5.6%), tannins (14.2-016.3%), mucilage and wax; a C-glycoside and beta-sitosterol.

Bergenin prevented stress-induced erosions in rats and lowered gastric outputs.

(Paashaanabheda indicates that the plant grows between rocks appearing to break them; it does not necessarily mean that it possesses lithotriptic property.)

Dosage: Rhizome—20-30 g for decoction. (API Vol. I)... bergenia ligulata

Saussurea Sacra

Edgew.

Habitat: Near snow line at elevations of 4,000 m and above in the Himalayas.

English: Yogiraj Plant, Sacred Saussurea.

Folk: Jogi-paadshaah (Kashmir), Ghuggi (Garhwal).

Action: Plant—used for nervous debility. Root—used for gynaecological disorders.... saussurea sacra

Smilax Aspera

Linn.

Family: Liliaceae.

Habitat: The tropical and temperate regions, from Kashmir, Sikkim and Assam to South India.

English: Italian Sarsaparilla.

Action: Roots used as a substitute for Hemidesmus indicus. Rutin has been isolated as a major flavonoid from the plant.... smilax aspera

Typha Laxmanni

Lepech.

Family: Typhaceae.

Habitat: Kashmir (Gilgit), at 2,700 m. English: Scented Flag. Ayurvedic: Airakaa. Folk: Pizh (Kashmir).

Action: Stamens—astringent and styptic. Used externally.... typha laxmanni

Betula Utilis

D. Don.

Synonym: B. bhojpattra Wall.

Family: Betulaceae.

Habitat: Temperate Himalaya from Kashmir to Bhutan.

English: Himalayan Silver Birch, Indian Paper tree.

Ayurvedic: Bhuurja, Bahulvalkala, Bahuputa, Lekhyapatraka, Charmi, Chitrapatra, Bhutahaa.

Folk: Bhojapatra.

Siddha/Tamil: Boorjapattram (leaves).

Action: Resin—laxative. Leaves— diuretic; used in the form of infusion in gout, rheumatism, dropsy, and as a solvent of stones in the kidneys; used in skin affections, especially eczema. Bark—used in convulsions. Oil—astringent, antiseptic.

Key application: (B. pendula) In irrigation therapy for bacterial and inflammatory diseases of the urinary tract and for kidney gravel; supportive therapy for rheumatic ailment. (German Commission E, ESCOP.)

European Silver Birch is equated with Betula alba L., synonym B. pendula Roth. Astringent, diuretic, anti- inflammatory, bitter, cholagogue; contains salicylates. Used for kidney and bladder complaints, sluggish kidney functions, rheumatism and gout. Methyl salicylate is obtained by distillation of the twigs. In an Indian sp., B. acuminata, methyl salicylate (92.8%) has been reported in the essential oil of the bark. B. utilis is also a close relative of B. pendula.

Dosage: Bark—3-5 g powder; decoction—50-100 ml (CCRAS.)... betula utilis

Bridelia Montana

Willd.

Family: Euphorbiaceae.

Habitat: The sub-Himalayan tract from Kashmir eastwards to Assam, and in Bihar, Orissa and Andhra Pradesh.

Ayurvedic: Ekaviraa.

Siddha/Tamil: Venge-maram.

Folk: Gondni, Asaanaa (Maharashtra).

Action: Bark and Root—astringent, anthelmintic. Used in the treatment of bone fracture.

The root contains 5.7% tannins.

The leaves contain beta-sitosterol, its beta-D-glucoside and a triterpe- noid. Fructose, glucose and sucrose were identified as the components of the glycoside.... bridelia montana

Brunella Vulgaris

Linn.

Synonym: Prunella vulgaris Linn.

Family: Labiatae; Lamiaceae.

Habitat: The Himalayas from Kashmir to Bhutan at altitudes of 1,400-4,000 m, in Khasi Hills and hills of South India.

English: Self-heal.

Unani: Substitute for Ustukhudduus. (Lavandula stoechas Linn.)

Folk: Dhaaru.

Action: Wound healing, expectorant, antiseptic, astringent, haemostatic, antispasmodic. Leaf- used in piles; and as a cooling herb for fevers.

The herb contains vitamins A, B, C and K; flavonoids; rutin. Flower spikes are liver-restorative, hypotensive, an- tioxidant.

Lupeol, stigmasterol and beta-sitos- terol are obtained from the unsapo- nifiable fraction from the leaves, the saponifiable fraction gave lauric,... brunella vulgaris

Bupleurum Flacutum

Linn.

Family: Umbelliferae; Apiaceae.

Habitat: The Himalayas from Kashmir to Bhutan and the Khasi Hills, at 1,000-4,000 m.

English: Hare's Ear.

Folk: Shingu (Himachal Pradesh), Sipil (Punjab), Thaanyo (Garhwal).

Action: Roots—anti-inflammatory, haemolytic, antipyretic. Used in inflammations, muscle stiffness, neurosis, pain and pyrexia. Roots resolve inflammations of costal margin and diaphragm.

Key application: Extracts have been used for the treatment of chronic hepatitis, nephrotic syndrome and auto-immune diseases (WHO.).

Therapeutic properties are attributed to saikoside or saikosaponins (yield from roots 2.06-3.02%), a complex mixture of triterpenic saponins. Saponin content varies with age. Saikos- aponins are analgesic, antipyretic as well as antitussive; anti-inflammatory on oral administration. In Japan and China, roots have been used traditionally in auto-immune diseases. Saikos- aponins form an ingredient of anti- tumour pharmaceuticals. A water- soluble crude polysaccharide fraction, prepared from the root, was reported to prevent HCl/ethanol-induced ulcero- genesis in mice significantly. Saiko- saponin-d, at a concentration of more than 5 ^m, inactivated measles virus and herpes simplex virus at room temperature.

Several sterols, possessing metabolic activities and plasma cholesterol- lowering activity, have also been isolated from the root.... bupleurum flacutum

Valeriana Pyrolaefolia

Decne.

Family: Valerianaceae.

Habitat: The temperate Himalayas from Kashmir to Bhutan.

Ayurvedic: Dhyaamaka (including among aromatic drugs of Jatamansi group.)

Folk: Sugandhabaalaa.

Action: Used as V. jatamansi.... valeriana pyrolaefolia

Viburnum Cotinifolium

D. Don.

Family: Caprifoliaceae.

Habitat: The Himalayas from Kashmir to Bhutan at altitudes of 1,200-3,300 m.

Folk: Richh, Richhabi, Khimor (Punjab), Gwiaa, Ghinwaa, Guyaa, Ghenu (Kumaon).

Action: Bark—used in menorrhagia and metrorrhagia.... viburnum cotinifolium

Carissa Opaca

Stapf. Ex Haines.

Synonym: C. spinarum auct. non L.

Family: Apocynaceae.

Habitat: Throughout the country in dry regions, especially in Punjab and Kashmir.

Ayurvedic: Karamardikaa.

Siddha/Tamil: Chirukila Chiru.

Folk: Jangali Karondaa. Garnaa (Punjab).

Action: Plant—cardiotonic. Root— purgative.

The root contains caffeic acid, cardiac glycosides—odorosides B, C, G and H, and evomonoside.

Carissa paucinervia A. DC. is also equated with the wild var. ofKarondaa.... carissa opaca

Carum Carvi

Linn.

Family: Umbelliferae; Apiaceae.

Habitat: Native to Europe and West Asia. Now cultivated in Bihar, Orissa, Punjab, Bengal, Andhra Pradesh, and in the hills of Kumaon, Garhwal, Kashmir and Chamba.

Also found wild in the North Himalayan regions.

English: Caraway.

Ayurvedic: Krishna jiraka, Jiraa, Kaaravi, Asita Jiraka, Kaashmira- jiraka, Prithvikaa, Upakunchikaa, Sugandha Udgaar, Shodhana.

Unani: Zeeraa Siyaah, Kamoon, Kamoon-roomi.

Siddha/Tamil: Shimai-shembu, Semai Seearagam, Karamjiragam.

Action: Carminative, antispas- modic, antimicrobial, expectorant, galactagogue, emmenagogue.

Key application: Seed oil—in dyspeptic problems, such as mild, sapstic conditions of the gastrointestinal tract, bloating and fullness. (German Commission E, ESCOP, The British Herbal Pharmacopoeia.) The Ayurvedic Pharmacopoeia of India recommended the seed in chronic fevers.

The fruit contains a volatile oil consisting of carvone (40-60%) and limoline with other constituents; flavonoids, mainly quercetin derivatives, polysac- charides and a fixed oil; also calcium oxalate.

The antispasmodic and carminative effects have been confirmed experimentally. The caraway has shown to reduce gastrointestinal foam.

Both the seeds and the essential oil are classed as carminative in I.P.

The essential oil shows moderate antibacterial and antifungal activity against several bacteria and fungi. Mixed with alcohol and castor oil, it is used for scabies.

Dosage: Seed—1-3 g powder. (CCRAS.)... carum carvi

Casearia Tomentosa

Roxb.

Synonym: C. elliptica Willd.

Family: Samydaceae; Flacourtiaceae.

Habitat: The Himalayas from Kashmir to Nepal, ascending to 1,000 m; throughout tropical India.

Ayurvedic: Chilhaka.

Siddha/Tamil: Kadichai.

Folk: Chillaa, Saptrangi.

Action: Root—hypoglycaemic. Root bark is used as a tonic in anaemic conditions.

Fruit pulp—diuretic, purgative, Leaves—anti-inflammatory. Fruit pulp —diuretic.

Ethanolic (80%) extract of the leaves showed significant anti-inflammatory activity in rats. Oil extracted from the seeds in rubbed on sprains. Various plant parts are used in neuralgia. and bladder. Chaksine has ganglion- blocking property. Chaksine and iso- chaksine possess a local anaesthetic effect intradermally. It produces a sustained fall in blood pressure of anaesthetized animals and produces a weak anti-acetylcholine effect. Roots also contains anthraquinones and aloe- emodin.

Dosage: Seed—3-6 g powder. (CCRAS.)... casearia tomentosa

Cedrus Deodara

(Roxb.) Loud.

Synonym: C. libani Barrel. var. deodara Hook. f.

Family: Pinaceae.

Habitat: North-western Himalayas from Kashmir to Garhwal, from 1,000 to 3,500 m.

English: Himalayan Cedar, Deodar.

Ayurvedic: Devadaaru, Suradru- ma, Suradaaru, Devakaashtha, Devadruma, Saptapatrika, Daaru, Bhadradaaru, Amarataru, Ama- radaaru, Daaruka, Devaahvaa, Surataru, Surabhuruha.

Unani: Deodaar.

Siddha/Tamil: Thevathaaram.

Action: Bark—decoction is used internally as astringent, antidiarrhoeal and febrifuge. Essential oil—antiseptic (used in skin diseases).

The Ayurvedic Pharmacopoeia of India indicated the use of the heart- wood in puerperal diseases.

The wood contains sesquiterpeno- ids; exhibits sapasmolytic activity. Alcoholic extract of the wood showed marked anti-inflammatory activity in mice; alcoholic extract showed antibacterial activity.

The wood possesses diaphoretic, diuretic and carminative properties, and is used in fevers and in pulmonary and urinary disorders.

Himalayan Cedarwood Oil contains two major sesquiterpenoids—alpha- and beta-himchalenes. Presence ofbu- tyric and caproic acids is also reported. The oil shows in vitro antibacterial and antifungal activity. It increases vascular permeability. Needles, on steam distillation, yield a volatile oil, rich in borneol and its esters. An alcoholic extract of the needles shows significant antibacterial activity against diptheria bacteria. The juice shows antiviral activity against tobacco mosaic virus and potato virus.

The bark contains 8-C methyltaxi- foline, dihydroquercetin, 8-C methyl- quercetin, quercetin, sitosterol, and tannins 8.25%, non-tannins 6.95% (varies with the age of the tree). An alcoholic extract of the bark shows significant activity against diptheria bacteria; aqueous extract of the dried bark showed anti-inflammatory activ ity against acute and chronic inflammations. Aqueous extract of the bark is found effective in reducing sugar content of diabetic patient's urine and blood to normal levels.

Dosage: Heartwood—3-6 g powder. (API Vol. IV.)... cedrus deodara

Chenopodium Ambrosioides

Linn.

Family: Chenopodiaceae.

Habitat: Native to West Indies and South America. Now distributed in South India, Bengal, Kashmir and Maharashtra in wet places with cultivated lands.

English: Indian Wormseed, Sweet Pigweed, Mexican Tea.

Ayurvedic: Sugandh-vaastuuka, Kshetra-vaastuuka.

Siddha/Tamil: Kattasambadam.

Folk: Khatuaa.

Action: Antispasmodic, pectoral, haemostatic, emmenagogue. Employed in treating nervous affections, particularly chorea. Dried herb—anthelmintic against round and hookworms.

Ascaridole, an active constituent of the oil, is highly active against round- worms, hookworms and small, but not large, tapeworms. It is highly toxic and can cause serious side effects.

The oil has been found useful in amoebic dysentery and intestinal infections (should be used with caution).

Leaves contain kaempferol-7-rham- noside and ambroside.

A decoction of the herb is given as an internal haemostatic and the infusion as an enema for intestinal ulceration. The infusion is sudorific and diuretic.

The oil exhibits antimicrobial and strong antifungal activity against human pathogenic fungi.... chenopodium ambrosioides

Chenopodium Botrys

Linn.

Family: Chenopodiaceae.

Habitat: The Himalaya, from Kashmir to Sikkim.

English: Feather Geramium, Jerusalem-Oak.

Folk: Jangaddi (Tibbet). Sahanik, Vaastuuka (Ladakh).

Action: Stimulant, diuretic, carminative, antispasmodic, emme- nagogue, pectoral. Used in asthma, catarrh; diseases of the stomach and liver. Seeds are considered toxic.

The herb contains flavonoids (including chrysoeriol and quercetin), also several sesquiterpenoids. Betaine is found in all parts of the plant.

Fresh herb yields an essential oil; Indian oil is reported to be devoid of as- caridole, the anthelmintic principle.... chenopodium botrys

Chrozophora Plicata

Hook. f.

Synonym: C. rottleri Klotzsh.

Family: Euphorbiaceae.

Habitat: Throughout India except Jammu & Kashmir and northeastern India as a weed.

Ayurvedic: Suuryaavart.

Folk: Nilakanthi.

Action: Ash of root—bechic. Leaf— depurative. Seed—cathartic.

Roots contain xanthone glycosides and a chromone glycoside. Seeds gave oil rich in linoleate. The plant contains 9.0% tannin.... chrozophora plicata

Chrysanthemum Indicum

Linn.

Synonym: Pyrethrum indicum L.

Family: Compositae; Asteraceae.

Habitat: Native to China and Japan. Cultivated as an ornamental.

English: Chrysanthemum.

Ayurvedic: Shatapatri.

Unani: Guldaaudi.

Siddha/Tamil: Samanthipoo, Akkarakkaram.

Action: Flowers—stomachic, aperient, anti-inflammatory. Leaves— prescribed in migraine (as circulatory stimulant). Uses same as those of chamomile.

The flowers contain daucosterol, cumambrin-A, glyceryl-l-monobehe- nate and palmitic acid. The flowers also contain chrysanthemol which showed strong anti-inflammatory activity in mice. The flavones, apigenin and lu- teolin, are reported to exhibit marked antitumour activity.

Flowers yield an essential oil containing camphor (16.0%), trans-cara- ne-trans-2-ol (15.0%), bornyl acetate (12.0%) and sabinene (7%).

A related species C. parthenium (Linn.) Berhh., Feverfew, synonym Tanacetum parthenium, used for the management of migraine in Western herbal, is found in Jammu and Kashmir. The plant extracts have a powerful and prostaglandin-independent inhibitory effect on the secretion of granule content by leucocytes and platelets. The inhibition of the agonist-induced serotonins release by platelets could be accounted for the benefit in migraine. The compound responsible for the anti-secretory activity has been identified as sesquiterpene alpha-methylene- gamma-lactone derivatives; partheno- lide being the main constituent of the lactones. (Two fresh or frozen leaves a day are chewed or capsules or pills containing 86 mg of the leaf material is taken for migraine. Fresh leaves may cause mouth sores.)... chrysanthemum indicum

Viburnum Nervosum

Hook. f. & Thoms.

Synonym: V. grandiflorum Wall. ex DC.

Family: Caprifoliaceae.

Habitat: The Himalayas from Kashmir to Sikkim at altitudes of 3,000-4,000 m.

Ayurvedic: Tilvaka.

Folk: Telam, Timoi (Kumaon), Tilen, Thelkaa (Garhwal).

Action: Bark—astringent; contain 13.1% tannin on dry basis.... viburnum nervosum

Viola Biflora

Linn.

Family: Violaceae.

Habitat: The temperate Himalayas from Kashmir to Sikkim at altitudes of 1,800-3,000 m.

Unani: Banafashaa (related species).

Action: Leaves—laxative, emollient. Flowers—antiseptic, pectoral, diaphoretic. Root—emetic.

The herb is used as a substitute for Banafashaa obtained from V. odorata.

The leaves are used for treating skin eruptions and the flowers for skin irritation.... viola biflora

Cimicifuga Racemosa

(Linn.) Nutt.

Family: Ranunculaceae.

Habitat: Temperate Himalayas from Kashmir to Bhutan up to at 3,000-4,000 m.

English: Black Cohosh Root, Black Snake Root.

Folk: Cohosh, Jiuenti (Punjab).

Action: Sedative, anti-inflammatory, antitussive, diuretic, emmenagogue. Used in homoeopathy for rheumatic diseases of nervous, hysterical women, suffering from uterine affections; also for locomotor ataxia.

Key application: In climacteric (menopausal), neurovegetative ailments, premenstrual discomfort and dysmenorrhoea. (German Commission E, ESCOP.)

The rhizome contains triterpene gly- cosides (including actein, cimigoside, cimifugine and racemoside; isofla- ones (including formononetin; isofer- ulic acid; volatile oil, tannin.

Pharmacological studies have shown that the menthol extract binds to oestrogen receptors in vitro and in rat uteri; this activity is thought to be due to the presence of formononetin. Racemoside exhibited antiulcer activity in mice. Isoferulic acid lowered body temperature in rats.

The rhizome is hypotensive in animals; a central nervous system depressant and antispasmodic in mice; causes peripheral vasodilation in human. Also exhibits anti-inflammatory (The British Herbal Pharmacopoeia) and hy- poglycaemic activity.

Actein has been studied for use in treating peripheral arterial disease. (Expanded Commission E Monographs.)

Clinically, the rhizome and root constituents of Black Cohosh does not seem to affect hormonal levels, such as estradiol, LH, FSH and pro- lactin. (Natural Medicines Comprehensive Database, 2007.)

Cimicifuga foetida L. root is used in bronchial and rheumatic diseases. Aqueous EtOH extract is used in cosmetic preparations for protecting skin; also used for preventing oral diseases and bad breath.

White Cohosh, used for urinogen- ital disorders, is equated with Actea pachypoda, synonym A. alba, A. rubra. Blue Cohosh has been identified as Caulophyllum thalictroides. It is toxic and abortifacient.... cimicifuga racemosa

Colchicum Luteum

Baker.

Family: Liliaceae.

Habitat: The temperate Himalayas from Kashmir to Chamba. Major supplies of the drug are received from Kashmir.

English: Hermodactyls, Colchicum, Meadow Saffron, Golden Collyrium (Indian substitute). (C. luteum is a good substitute for C. autumnale L. which is official in the B.P.)

Ayurvedic: Hiranyatuttha.

Unani: Suranjaan Talkh.

Action: Non-steroidal antiinflammatory, anti-gout (relieves inflammation and pain of acute gout but does not increase expulsion of uric acid, is used with an alkaline diuretic), emetic, cathartic. Anti-chemotactic, antiphlogistic, inhibitor of mitosis. Highly toxic. Used for external application to lessen inflammation and pain.

Key application: In acute gout attack. (German Commission E.)

The fresh corms and aerial parts of a sample from Jammu yielded 0.94% and 070% of total alkaloids, the major being colchicine 0.40% and 0.20% respectively. Colchicine analogs— decteyl thiocolchicine (DTC), decetyl- methylcolchicine (DMC) and tri- methylcolchicinic acid (TMCA) were effective in the treatment of gout; DTC may elicit agranulocytosis.

Colchicine binds to tubulin, the protein subunit of microtubules. Its most important biological effect is the inhibition of processes that depend upon microtubule function by blocking polymerization. In preventing micro- tubule formation, colchicine has been shown to inhibit catecholamine secretion from adrenal medulla, iodine secretion from thyroid gland and pro- lactin secretion from pituitary tumour cells. It inhibits stimulated insulin secretion from isolated perfused pancreas and islets in vitro.

The use of Colchicum for long periods is not recommended owing to its toxicity in larger doses (even 7 mg of colchicine has caused death) and its depressant action upon central nervous system.

Prolonged use of Colchicum autum- nale may cause agranulocytosis, aplas- tic anaemia and peripheral nerve inflammation. (Sharon M. Herr.)... colchicum luteum

Viola Odorata

Linn.

Family: Violaceae.

Habitat: Native to Europe; cultivated in Kashmir.

English: Sweet Violet.

Unani: Banafashaa, Banafsaj, Kakosh, Fareer.... viola odorata

Viola Pilosa

Blume.

Family: Violaceae.

Habitat: Kashmir to Sikkim and Nilgiri hills at 1,500-2,100 m.

Unani: Banafashaa (related species)

Folk: Thungtu (Kumaon).

Action: Uses same as those of V odorata. A medicinal oil of Unani medicine, Roghan-e-Banafashaa, is prepared from the plant. Flowers, as tea, are used for treating headache.

Active principle of the herb is an alkaloid, violine.... viola pilosa

Corydalis Govaniana

Wall.

Family: Papaveraceae.

Habitat: The West Himalayas, from Kashmir to Kumaon.

Ayurvedic: Bhootakeshi (a doubtful substitute for Bhootajataa, Nardostachys jatamansi DC.) Species of Selinum are also used as Bhootakeshi.

Action: Sedative, spasmolytic, hypotensive, nervine, antiseptic. Used in cutaneous and scrofulous affections, chronic fever and liver complaints.

The roots contain phthalide iso- quinoline alkaloids. In addition, stems and leaves contain tetrahydroproto- berberines.

A related species, C. solida, indigenous to Siberia, northern China and Japan, contains alkaloids including corydalmine, tetrahydropalmatine, protoberberine-type alkaloid lenticin. The alkaloids are analgesic and sedative and have been shown to work, at least in part, by blocking the dopamine receptors in the central nervous system.

The powdered rhizome of Corydalis possesses one-hundredth of the analgesic potency of morphine.... corydalis govaniana

Corylus Colurna

Linn.

Family: Betulaceae.

Habitat: Western temperate Himalayas from Kashmir to Kumaon; common in Kashmir forests.

English: Turkish Hazel.

Folk: Virin (Kashmir). Thangi, Urni (Punjab). Kapaasi, Bhotiaa Badaam (Kumaon).

Action: A mixture of flavonoids, isolated from the leaves, has shown potent antiperoxidative and oxygen radical scavenging properties. It exhibits very low toxicity and can be used as an alternative to the toxic synthetic antioxidants used for the treatment of free radical-mediated injuries. See also C. avellana.

Himalayan Hazel, occurring in central and eastern Himalayas, locally known as Curri and Langura, is equated with Corylus ferox Wall.... corylus colurna

Crataegeus Oxyacantha

Linn.

Family: Rosaceae.

Habitat: British and European hedge plant, met with in the temperate Himalayas of Kashmir and Himachal Pradesh at an altitude of 1,800-3,000 m. (The plant does not thrive in the plains of India.)

English: English Hawthorn.

Folk: Ring, Ringo, Pingyat, Phindak, Ban Sanjli (Punjab hills).

Action: Coronary vasodilator (strengthens heart muscle without increasing the beat in coronary arteries), antispasmodic, antihypertensive, sedative to nervous system, diuretic.

Key application: In cases of cardiac insufficiency Stage II as defined by NYHA (New York Heart Association). An improvement of subjective findings as well as an increase in cardiac work tolerance, a decrease in pressure/heart rate product, an increase in the ejection fraction and a rise in the anaerobic threshold have been established in human pharmacological studies. (German Commission E, WHO.)

The active principles include oligo- meric procyanidins and flavonoids.

The drug is official in Homoeopathic Pharmacopoeia of India.

Contraindicated in low blood pressure, chest pain, bleeding disorders. The herb may interfere with therapeutic effect of cardiac drugs. (Sharon M. Herr.) Preparations based on hydroal- coholic extracts of Crataegus monogy- na or C. laevigata are used as Hawthorn in the Western herbal.... crataegeus oxyacantha

Crocus Sativus

Linn.

Family: Iridaceae.

Habitat: Cultivated in Kashmir up to 2,000 m and in Chaubattia in Uttar Pradesh.

English: Saffron, Crocus.

Ayurvedic: Kumkuma, Rudhira, Vadrika, Kaashmira, Kaashmiraka, Vaalhika, Agnishikhaa, Ghrusrrn, Rakta, Kshataja. Keshara (usually Keshara indicates Naagakeshara, Mesuaferrea Linn.)

Unani: Zaafraan.

Siddha/Tamil: Kumgumappoo (dried stigma).

Action: Stigma and style—nervine tonic, sedative, antispasmodic expectorant (in dry cough, whooping cough, bronchitis), stomachic, diaphoretic, emmenagogue.

The Ayurvedic Pharmacopoeia of India indicated the use of the stigma and style in migraine, chronic sinusitis, and in urinary obstruction, inflammation of the urinary tract.

The saffron is used in Chinese medicine for melancholia, depression, shock and menstrual disorders.

Saffron contains a volatile oil composed of terpenes, terpene alcohols and esters. The herb also contains crocin, picrocrocin, crocetin, carotenoids and riboflavin and thiamine.

Preliminary evidence suggests that crocetin may improved atherosclerosis by increasing plasma oxygen diffusion and decreasing cholesterol and triglyceride levels. In addition, cro- cetin binds to albumin, potentially increasing oxygen diffusion and improving atherosclerosis. (Natural Medicines Comprehensive Database, 2007.)

The stigma showed remarkable inhibitory effect on blood coagulation due to the presence of platelet aggregation inhibitor containing adenosine. It accelerated in vitro fibrinolytic activity of urokinase and plasmin.

Small amounts of Saffron stimulate gastric secretion; larger amounts stimulate uterine smooth muscle and exhibit emmenagogue and abortifacient effects.

Saffron extract showed cytotoxic and antimutagenic activity and antitu- mour activity against ascites tumours in mice. Chemical analysis indicated that the naturally occurring crocin may be the active principle responsible for the observed anticancer activity.

A xanthone, carotenoid glycosidic conjugate, mangi-crocin, isolated from saffron, showed significant adapto- genic activity. A natural antioxidant, isolated from saffron stem callus, showed better antioxidant activity than vitamin E. Saffron bulbs are toxic, stigmas in overdoses narcotic.

The dose of stigma and styles at 1.55.0 g is toxic. (Recommended dose : 0.5-1.5 g per day).

Dosage: Dried style and stigma—20-50 mg (API Vol. IV.)... crocus sativus

Cydonia Oblonga

Mill.

Synonym: C. vulgaris Pers.

Family: Rosaceae.

Habitat: Cultivated in Punjab, Kashmir and the Nilgiri hills.

English: Quince Fruit.

Ayurvedic: Amritaphala, Paatalaa, Simbitikaa.

Unani: Bihi, Bihidaanaa.

Siddha/Tamil: Shimaimathala.

Action: Fruit pulp and seeds— soothing and demulcent; used in irritable bowel syndrome, diarrhoea, dysentery, constipation, and in irritable conditions of the mucous membrane. Leaf, bud and bark—astringent. Fruit— expectorant. Mucilage—used externally for scalds, ulcers and burns.

The seed kernel contains the gly- coside amygdalin, tannin, mucilage (about 22%), ash (1.3%) and fatty oil (l4-19%).

In Greece, a tea prepared by boiling dry seeds in water is given in cystitis. The major water-soluble polysac- charide in the mucilage of seeds contains a high proportion of glucuronic acid residues.

The fruit contains pectin (yield 0.53% fresh weight) and is similar to that of apple. Ionone glycosides, along with octadienoic acid and its diol, have been isolated from the fruit.

Fruit juice contains thiamine, riboflavin, nicotinic acid, vitamin B6, inositol, pantothenic acid, folic acid and biotin.

The essential oil also gave a number of ionone-related compounds. The buds contain a cyanogenetic glycoside. The bark and shoots yield hydrocyanic acid on distillation.... cydonia oblonga

Cymbopogon Jwarancusa

(Jones) Schult.

Synonym: Andropogon jwarancusa Jones.

Family: Poaceae.

Habitat: Himalayas from Kashmir to Assam, ascending up to more than 300 m and in the north-western plains.

Ayurvedic: Bhuutikaa, Laamajja- ka, Laamajja. (Subs. Vetiveria zizanioides (L.) Nash.)

Unani: Izkhar.

Action: Blood purifier, bechic, anticholerin, emmenagogue, febrifuge, antirheumatic (also used in gout). Flower—styptic. Essential oil—antimicrobial.

Major constituent of the essential oil is piperitone (64.7%) others include borneol, cadinene, camphene, camphor, farnesene, geraniol, alpha-and beta-pinene. The antibacterial activity is attributed to piperitone.... cymbopogon jwarancusa

Daphne Oleoides

Schreb.

Family: Thymelaeaceae.

Habitat: The Western Himalayas and Kashmir at 1,000-3,000 m.

English: Mezereon.

Folk: Kutilal, Kanthan (Punjab).

Action: Active principles are attracting scientific interest. The orthoesters are co-carcinogenic and mezerein antileukaemic in experimental studies. Bark— used as an ointment for inducing discharge from indolent ulcers. Bark, root and root bark—used mainly for obstinate cutaneous diseases, especially for eczema with severe itching and copious exudation (weeping eczema).

As the plant is poisonous, it is used in homoeopathic dilutions internally and topically.

The bark gave diterpenes including mezerein, daphnetoxin (0.02%). Mezerein is anti-inflammatory and anticar- cinogenic. Daphnetoxin is poisonous. Seeds contain daphnane ester (0.1%) and daphnetoxin (0.02%).

EtOH extract showed significant activity against P-388 lymphocytic leukemia and L-1210 leukemia in mice, due to mezerein.... daphne oleoides

Datisca Cannabina

Linn.

Family: Datiscaceae.

Habitat: Temperate and subtropical Himalaya from Kashmir to Nepal at 300-1,800 m.

English: False Hemp.

Folk: Akal-ber. Bhang-jala (Punjab).

Action: Diuretic, purgative, expectorant. Used in fevers, and gastric and scrofulous ailments.

The plant contains flavonoids, datis- cin and datiscanin. EtOH (50%) extract of seeds and flowers exhibited marked sedative, highly anti-inflammatory, mild analgesic, antipyretic and diuretic activity in rats.... datisca cannabina

Datura Stramonium

Linn.

Synonym: D. tatula Linn.

Family: Solanaceae.

Habitat: The Himalaya from Kashmir to Sikkim up to 2,700 m, hilly districts of Central and South India.English: Thornapple, Jimsonweed, Stramonium.Ayurvedic: Krishnadhattuura, Dhuurta (black seed var.), Unmatta, Kitav, Tuuri, Maatul, Madan.

Unani: Dhaturaa.

Action: Spasmolytic, antiasthmatic, anticholinergic, cerebral depressant, nerve-sedative. Controls spasms of bronchioles in asthma. Anticholinergic. Effects of overdose are similar to those of atropine. Temporary relief from Parkinsonian tremor recorded. (Contraindicated with depressant drugs.) Applied locally, stramonium palliates the pain of muscular rheumatism, neuralgia, also pain due to haemorrhoids, fistula, abscesses and similar inflammations. Prevents motion sickness.

Key application: In diseases of the autonomic nervous system. (Included among unapproved herbs by German Commission E.) The British Herbal Pharmacopoeia reported antispasmodic action of the leaf; Indian Herbal Pharmacopoeia accepted it as expectorant and antispasmodic. Whole plant contains 0.26% alkaloids (seeds 0.98% and stem 0.08%); also flavonoids, withanolides, cou- marins and tannins; the major alkaloid is hyoscyamine (44-67%), hyoscine (13.2-25.3%) and atropine (0.01-0.1%). The tropane alkaloids are similar to those found in Atropa belladonna. Hyoscine is five times as active as atropine in producing mydriasis, but its main use is as antimotion sickness drug; and in combination as a sedative.Toxic constituents include anti- cholinergic alkaloids.

Dosage: Leaf—60-185 mg powder; seed—60-120 mg powder (CCRAS.)

... datura stramonium

Delphinium Denudatum

Wall.

Synonym: D. pauciflorum Royle.

Family: Ranunculaceae.

Habitat: The temperate Himalayas from Kashmir to Kumaon at altitudes of 2,400-3,600 m.

English: Larkspur. Ayurvedic: Nirvishaa, Nirvishi. (Kyllinga triceps Rottb. is used as a substitute for Nirvishaa.)

Unani: Jadwaar Khataai, Maatiryaaq.

Folk: Root—astringent, vulnerary, deobstruent, alterative. Used for painful piles, muscular atrophy, gout and as a nervine tonic. Also used as an adulterant for aconite.

Oral administration of the aqueous extract of the plant to rats with CCl4- induced hepatotoxicity revealed hepa- toprotective property of the plant.

The roots contain campesterol, stig- masterol, sitosterol, cholesterol, delta- avenasterol and alkaloids including de- nudatine, denudatidine, condelphine, talatizidine and iso-talatizidine.... delphinium denudatum

Delphinium Vestitium

Wall. ex Royle.

Synonym: Delphinium elatum auct. non Linn.

D. speciosum Janka ex Nym.

Family: Ranunculaceae.

Habitat: The temperate Himalaya from Kashmir to Nepal to 2,7004,700 m.

English: Candle Larkspur, Bee Larkspur.

Ayurvedic: Nirvisha.

Action: Whole plant—cardiac and respiratory depressant, emetic, diuretic, anthelmintic. Seed— insecticidal. Used in skin eruptions. Powdered flowers, mixed with mustard oil, are used for destroying lica.

The plant contains beta-sitosterol and alkaloid delpheline; aerial parts contain an alkaloid, elatine.

Seeds are very poisonous; contain several aconitine-like alkaloids. Del- phinidine, isolated from seeds, causes drastic gastro-enteric irritation.... delphinium vestitium

Descurainia Sophia

(Linn.) Webb ex Prantl.

Synonym: Sisymbrium sophia L.

Family: Brassicaceae.

Habitat: Temperate Himalaya from Kashmir to Kumaon at 2,200-4,100, also in eastern Himalaya.

English: Flix Weed, Flax Weed.

Action: Leaf and flower—astringent, antiscorbutic. Seed—expectorant, anti-inflammatory, febrifuge, antidysenteric. Aerial parts— antiviral, hypoglycaemic.

The plants has been used externally for ulcers, seeds are used as substitute or adulterant of the seeds of Sisymbrium iro Linn. (The source of Khaakasi, Khubb, Tukhm-e-Shahuh, Khuubkalaan of Unani medicine, known as Hedge Mustard or London Rocket.)... descurainia sophia

Desmodium Triflorum

(Linn.) DC.

Synonym: Hedysarum triflorum Linn.

Family: Fabaceae.

Habitat: Throughout India, in the plains ascending to 1,200 m in Kumaon and 1,800 m in Kashmir.

Ayurvedic: Tripaadi, Hamsapaadi (Kerala).

Siddha/Tamil: Seruppadi.

Folk: Jangali Methi, Ran-methi.

Action: Fresh leaves—used internally as galactagogue and for diarrhoea; applied externally to wounds and abscesses. Root— diuretic. Also used for cough, asthma.

The leaf contains alkaloids (0.010.15%), major being beta-phenylethyl- amine; also contains tyramine and hy- paphorine. Hypaphorine is present in roots as well. Root contains 0.010.02% alkaloids.... desmodium triflorum

Dictamnus Albus

Linn.

Family: Rutaceae.

Habitat: Western Himalayas from Kashmir to Kunawar, common in Pangi.

English: Gas Plant, Dittany, Burning Bush.

Action: Root bark—used in nervous diseases, hysteria, intermittent fevers, urinogenital disorders, and amenorrhoea; a decoction for scabies and other skin affections. Toxic.

Dittany stimulates the muscles of the uterus, while its effect on the gastro-intestinal tract is antispasmod- ic, it relaxes the gut. (The plant is used in Greek folk medicine as anti- spasmodic.) The herb contains furo- quinoline alkaloids (including dictam- nine), furococumarins, limonoids, and flavonoids (including rutin).

Volatile oil contains estragol, anet- hole, and a toxic alkaloid dictamnine. Flowers yield 0.05% essential oil containing methylchavicol and anethole. Leaves yield 0.15% essential oil.... dictamnus albus

Digitalis Lanata

Ehrh.

Habitat: Native to Europe. Now cultivated mainly in Kashmir (Yarikhah), also occurs wild.

English: Grecian Foxglove.

Ayurvedic: Hritpatri, Tilapushpi (non-classical). (Yellow var.)

Action: See D. purpurea.

Earlier, the herb was used to treat ulcers, boils, abscesses, headaches and paralysis. William Withering, an 18th century English country doctor, explored the plant's hidden properties. His work led to the production of digoxin, a life-saving medicine.

Safety of the herb cannot be established due to variable amounts of cardiac glycosides. The powder is toxic at 520 mg.... digitalis lanata

Digitalis Purpurea

Linn.

Family: Scrophulariaceae.

Habitat: Native to West Europe. Cultivated in Tangmarg and Kishtawar in Kashmir, Darjeeling and the Nilgiris.

English: Digitalis, Foxglove.

Ayurvedic: Hritpatri, Tilapushpi (non-classical). (Purple var.)

Action: Main source of digoxin for the pharmaceutical industry. Digitalis glycosides increase the force of contraction of heart without increasing the oxygen consumption and slow the heart rate when auricular fibrillation is present. To be used only under strict medical supervision.

Not used as a herbal drug.... digitalis purpurea

Dioscorea Deltoidea

Wall ex Griseb.

Synonym: D. nepalensis Sweet ex Bernardi.

Family: Dioscoreaceae.

Habitat: The Himalaya from Kashmir to Arunachal Pradesh and in Assam at 450-3,100 m.

Ayurvedic: Vaaraahikanda (var.), Grishti.

Folk: Gun, Kris (Punjab).

Action: Tuber—antipthiriac. Leaf— febrifuge. The rhizomes are a rich source of diogenin and its glycoside. Steroidal saponins have also been isolated. Diogenin is used in the preparation of various steroidal drugs.

Synonym: D. hispada Dennst. D. hirsuta Dennst.

Family: Dioscoreaceae.

Habitat: Sikkim, the Himalayas, Khasi Hills.... dioscorea deltoidea

Dracocephalum Moldavica

Linn.

Family: Lamiaceae.

Habitat: The temperate Western Himalaya in Kashmir from 2,1002,400 m.

Ayurvedic: Raam Tulasi.

Unani: Feranjmushk

Action: Seeds—Febrifuge, carminative, astringent, demulcent, vulnerary. Used is cephalalgia, neurological disorders, as a cardiac tonic, brain tonic and deobstruent in Unani medicine.

Citral and geranyl acetate are major constituents of the essential oil. Others include alpha-pinene, nerol, cit- ronellol, linalool, geraniol, limonene and caproic acid. Flavonoids, including moldavoside, have been isolated from the plant.... dracocephalum moldavica

Dryopteris Filix-mas

(Linn.) Schoutt

Synonym: Aspidium filix-mas Linn.

Family: Polypodiaceae.

Habitat: Temperate regions of America, Europe, Asia, near damp and shady terrains.

English: Male Fern, Aspidium.

Unani: Sarakhs, Sarakhs Muzakkar.

Siddha/Tamil: Iruvi.

Action: Taenifuge, vermifuge (normally used in conjunction with a saline purgative, not used with castor oil.) Also, deobstruent, abor- tifacient.Externally for rheumatism, sciatica and neuralgia. No more in use as an anthelmintic as better alternatives are available.

Rhizomes and fonds contain filicin (2%), a mixture of dimeric, trimer- ic and tetrameric butanone chloroglu- cosides, that kills tapeworms. Excessive dose of filicin may cause intestinal cramps and blindness, also liver damage.

Related Himalayan species include: D. odontoloma (Kashmir valley), D. marginata, D. barbigera (Kashmir to Sikkim), D. schimperiana (Mussoorie) and D. blanfordii (Chattri, Cham- ba).The ferns gave filicin 2.3, 2.1, 2.1, 4.4 and 3.5%, respectively.... dryopteris filix-mas

Eleusine Indica

Gaertin.

Family: Gramineae, Poaceae.

Habitat: Australia, North America; throughout the warmer parts of the world. In India, in wet plains and low hills and pasture grounds.

English: Crowfoot Grass, Crab Grass.

Ayurvedic: Nandimukha (var.).

Folk: Nandiaa (Orissa), Mahaar Naachni (Maharashtra), Thippa Ragi (Tamil Nadu).

Action: Used for biliary disorders. In Vietnamese traditional medicine, a decoction of the whole plant is used as stomachic, diuretic, febrifuge, and in sprains.

Aerial parts contain vitexin, 3-O- beta-D-glucopyranosyl-beta-sitosterol and its 6'-O-palmitoyl derivatives. of intoxication. Used for abdominal pains, nausea, bleeding nose. Fresh plants from Uttaranchal gave 0.4% essential oil having dehydroelsholtzia ketone 88.7% as the main constituent, followed by humulene 2.4% and caryophyllene 0.9% (the oil composition of the species which grow in Japan and Kashmir is different.)

Plant contains linarin, apigenin and 7-O-glucosides of apigenin and lute- olin.

The Japanese species, used for hangovers, gave compounds including tri- terpenoids, steroids and flavonoids.

Elsholtzia blenda Benth., synonym Perilla elata D. Don, is also equated with Ban-Tulasi. Major constituent of the essential oil is geranyl acetate. Other constituents are p-cymene, sa- binene, borneol, geraniol, linalyl acetate, fernesol, limonene, linalool, cit- ronellol, thymol and nerolidol.... eleusine indica

Ephedra Gerardiana

Wall. ex Stapf.

Family: Ephedraceae.

Habitat: The drier regions of the temperate and alpine Himalayas from Kashmir to Sikkim from 2,350 to 5,350 m.

English: Ephedra (Ephedra sinica Stapf.)

Ayurvedic: Soma, Soma-valli (substitute).

Folk: Asmaaniyaa, Budaagur (Punjab); Tipat, Traani (Himalayan region).

Action: Circulatory stimulant, bron- chodilator, vasodilator, antiallergic, antiasthmatic (usualy given with expectorants), diaphoretic. Not prescribed with antidepressants.

Key application: Ephedra sinica— in diseases of the respiratory tract and mild bronchospasms. Also in acute coryza, allergic rhinitis and sinusitis. (German Commission E.) In the treatment of nasal congestion due to hay fever, allergic rhinitis, acute coryza, cold, sinusitis and as abronchodilator. (WHO.)

Contraindicated in anxiety, restlessness, high blood pressure, glucoma, impaired circulation of the cerebrum, adenoma of prostate with residual urine accumulation, pheochromocy- toma, thyrotoxicosis. (German Commission E.)

Ephedra is official in the national pharmacopoeias of China, Japan and Germany. The herb is listed in Ayurvedic Pharmacopoeia. Only its isolated derivatives, ephedrine and ephedrine hydrochloride are official in Indian Pharmacopoeia.

Ephedrine is toxic at more than 300 mg in 1 day (Francis Brinker.)

Aerial parts yielded ephedrine and ephedroxane. Pseudoephedrine is the most active anti-inflammatory principle of Ephedra sp., it exhibited inhibitory action on a number of acute inflammations. Ephedroxane possesses a minor anti-inflammatory principle. Among the Indian species, Ephedra major, found in Lahul, contains over 2.56% alkaloids of which nearly three fourths is ephidrine. Ephedra gerardiana contains 1.22% total alkaloids and 0.68% ephedrine.

On 30 December 2003, the FDA banned ephedra products in the US.... ephedra gerardiana

Euphrasia Simplex

D. Don.

Synonym: E. officinalis Linn.

Family: Scrophulariaceae.

Habitat: The Temperate Himalaya from Kashmir to Sikkim, from 1,350 to 4,000 m.

English: Eyebright.

Action: Plant—astringent, antiallergic, bechic, anticatarrhal.

Key application: Externally as lotions, eye-baths, poultices, for eye complaints associated with inflammatory conditions, and as a preventive measure against mucus of the eyes, "glued" and inflammed eyes. (Traditional uses mentioned by German Comission E.)

Orally, Eyebright is used to treat allergies, common cold, bronchial conditions and sinusitis. Ophthalmic application is not recommended. Eye- bright has been used in a British herbal tobacco product, which was smoked for cold and chronic bronchial conditions.

Aerial parts showed presence of phenol, carboxylic acid, flavones and methyl flavone derivatives. Plant gave quercetin glucoside, diosmetin, kaem- pferol, caffeic and ferulic acids, stig- masterol and beta-sitosterol. Iridoid glycosides, including aucubin, are also present. Tannins include both condensed and hydrolysable gallic acid type.... euphrasia simplex

Euryale Ferox

Salisb.

Family: Nymphaeaceae.

Habitat: Kashmir, Bihar, Rajasthan, Assam, Manipur, Tripura, Bengal and Uttar Pradesh, in lakes and ponds.

English: Gorgan Nut, Fox Nut.

Ayurvedic: Makhaann, Paaniyapha- la, Padma-bijaabha, Ankalodya.

Unani: Makhaanaa.

Action: Seed—deobstruent, astringent, nervine tonic. Used in spermatorrhoea and sexual affections (restrains seminal gleet) and debility.

Edible parts of the seeds gave the following values: moisture 12.8, protein 9.7, fat 0.1, mineral matter 0.5, carbohydrates 76.9, calcium 0.02, and phosphorus 0.09%; iron 1.4 mg/100 g.... euryale ferox

Fenugreek

Trigonella foenum-graecum

Fabaceae

San: Methika, Methi, Kalanusari;

Hin: Meti, Mutti; Ben, Mar: Methi;

Mal: Uluva;

Tam: Ventayam;

Kan: Mentya, Menlesoppu;

Tel: Mentulu, Mentikura; Arab: Hulabaha

Importance: Fenugreek or Greek Hayes is cultivated as a leafy vegetable, condiment and as medicinal plant. The leaves are refrigerant and aperient and are given internally for vitiated conditions of pitta. A poultice of the leaves is applied for swellings and burns. Seeds are used for fever, vomiting, anorexia, cough, bronchitis and colonitis. In the famous Malayalam treatises like ‘Padhyam’ ‘Kairali’ and ‘Arunodhayam’, uluva is recommended for use as kalanusari in Dhanvantaram formulations of ‘Astaghradayam’. An infusion of the seeds is a good cool drink for small pox patients. Powdered seeds find application in veterinary medicine. An aqueous extract of the seeds possesses antibacterial property (Kumar et al, 1997; Warrier et al, 1995).

Distribution: Fenugreek is a native of South Eastern Europe and West Asia. In India fenugreek is grown in about 0.30 lakh ha producing annually about 30,000 tonnes of seeds. The major states growing fenugreek are Rajasthan, Madhya Pradesh, Gujarat, Uttar Pradesh, Maharashtra, Punjab and Karnataka. It is grown wild in Kashmir and Punjab.

Botany: Trigonella foenum-graecum Linn. belongs to family, Fabaceae. It is an annual herb, 30-60cm in height, leaves are light green, pinnately trifoliate, leaflets toothed, flowers are white or yellowish white, papilionaceous and axillary. Fruits are legumes, 5-7.5cm long, narrow, curved, tapering with a slender point and containing 10-20 deeply furrowed seeds per pod. There are two species of the genus Trigonella which are of economic importance viz. T. foenum graecum, the common methi and T. corniculata, the Kasuri methi. These two differ in their growth habit and yield. The latter one is a slow growing type and remains in rosette condition during most of the vegetative growth period (Kumar et al, 1997; Warrier et al, 1995).

Agrotechnology: Fenugreek has a wide adaptability and is successfully cultivated both in the tropics as well as temperate regions. It is tolerant to frost and freezing weather. It does well in places receiving moderate or low rainfall areas but not in heavy rainfall area. It can be grown on a wide variety of soils but clayey loam is relatively better. The optimum soil pH should be 6-7 for its better growth and development. Some of the improved cultivars available for cultivation are CO1 (TNAU), Rajendra Kanti (RAU), RMt-1(RAU) and Lam Selection-1 (APAU). Land is prepared by ploughing thrice and beds of uniform size are prepared. Broadcasting the seed on the bed and raking the surface to cover the seeds is normally followed. But to facilitate intercultural operations, line sowing is also advocated in rows at 20-25cm apart. Sowing in the plains is generally in September-November while in the hills it is from March. The seed rate is 20-25kg/ha and the seeds germinate within 6-8 days. Besides 15t of FYM, a fertiliser dose of 25:25:50kg NPK/ha is recommended. Entire P,K and half N are to be applied basally and the remaining half N 30 days after sowing. First irrigation is to be given immediately after sowing and subsequent irrigations at 7-10 days interval. Hoeing and weeding are to be done during the early stages of plant growth and thinning at 25-30 days to have a spacing of 10-15cm between plants and to retain 1-2 plants per hill. Root rot (caused by Rhizoctonia solani) is a serious disease and can be controlled by drenching carbendazim 0.05% first at the onset of the disease and another after one monthof first application. In about 25-30 days, young shoots are nipped off 5cm above ground level and subsequent cuttings of leaves may be taken after 15 days. It is advisable to take 1-2 cuttings before the crop is allowed for flowering and fruiting when pods are dried, the plants are pulled out, dried in the sun and seeds are threshed by beating with stick or by rubbing with hands. Seeds are winnowed, cleaned and dried in the sun. They may be stored in gunny bags lined with paper. An yield of 1200-1500kg of seeds and about 800-1000kg of leaves may be obtained per hectare in crops grown for both the purposes (Kumar et al, 1997).

Properties and activity: Seeds contain sapogenins-diosgenin, its 25-epimer(yamogenin), tigogenin, gitogenin, yuccagenin, 25-2-spirosta-3-5-diene and its -epimer. Seeds also contain a C27-steroidal sapogenin-peptide ester-fenugreekine. Seeds, in addition, contain 4-hydroxyleucine and saponins-fenugrins A-E:two furostanol glycoxides-trigonelloxide C and (255)-22-O-methyl-52-firostan-3 ,22,26,triol-3-O- -rhamnopyrans syl(1-2) C- -D-glucopyranosyl (1-3)- -D- glucopyranoxide-26-O- -D-glucopyranoxide.

Other chemical constituents are sterols- -sitosterol and cholesterol, flavone C- glycosides-vitexin, iso-vitexin, vitexin-2”-O-P-coumarate and vicenin-2. Flavonoids- quercetin and luteolin, flavonoid glycoside-vicenin-I. Invitro seedling callus culture gave flavonoids-luteolin and vitexin-1-glycoside. An essential oil is also reported from seeds. Leaves gave saponins-gracecunins A-G, flavonoids- kaempferol and quercetin; sterols- - sitosterol, sapogenins-diosgenin, gitogenin coumarin-scopoletin is also reported from the plant.

Seeds are bitter, mucilaginous, aromatic, carminative, tonic, diuretic, thermogenic, galactagogue, astringent, emollient, amophrodisiac, antirheumatic, CNS depressant and antiimplantation. Fenugreekine is hypoglycaemic, diuretic, hypotensive, cardiotonic, antiphlogistic. It showed 80% inhibition of vaccina virus.... fenugreek



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