A fibrous protein that is the main constituent of the tough outermost layer of the skin, nails, and hair.
The substance of which horn and the surface layer of the skin are composed.
n. one of a family of proteins that are the major constituents of the nails, hair, and the outermost layers of the skin. The cytoplasm of epithelial cells, including *keratinocytes, contains a network of keratin filaments.
(cornification) n. the process by which cells become horny due to the deposition of *keratin within them. It occurs in the *epidermis of the skin and associated structures (hair, nails, etc.), where the cells become flattened, lose their nuclei, and are filled with keratin as they approach the surface.... keratinization