Persistent dryness of the cornea and conjunctiva caused by deficiency in tear production. The condition is associated with autoimmune disorders such as rheumatoid arthritis, Sjögren’s syndrome, and systemic lupus erythematosus. Prolonged dryness may lead to blurred vision, itching, grittiness, and, in severe cases, the formation of a corneal ulcer. The most effective treatment is frequent use of artificial tears (see tears, artificial).