An amino acid present in some foods and plants. Prepared synthetically in the laboratory when used as the basic medication for Parkinson’s disease. Has enabled millions of elderly sufferers to lead a useful and less painful life with reduced muscle tension. On entering the brain the substance is known as dopamine.
In old age the concentration of L-dopa in the brain decreases. This substance is available in very high concentrations in the plant Vivia faba (broad bean). Highest concentration is found in type WH 305. Research has shown that regular eating of these golden beans can prolong life expectancy, slow down the ageing process and possibly allow a reduced dosage in medication.
n. see levodopa.
lead1 n. a soft bluish-grey metallic element that forms several poisonous compounds. Acute lead poisoning, which may follow inhalation of lead fumes or dust, causes abdominal pains, vomiting, and diarrhoea, with paralysis and convulsions and sometimes *encephalitis. In chronic poisoning a characteristic bluish marking of the gums (‘lead line’) is seen and the peripheral nerves are affected; there is also anaemia. Treatment is with *edetate. The use of lead in paints is now strictly controlled. Symbol: Pb.
lead2 n. 1. a portion of an electrocardiographic record that is obtained from a single electrode or a combination of electrodes placed on a particular part of the body (see electrocardiogram; electrocardiography). In the conventional ECG, 12 leads are recorded. Each lead represents the electrical activity of the heart as ‘viewed’ from a different position on the body surface and may help to localize myocardial damage. 2. a flexible steerable insulated wire introduced into the heart under X-ray control to allow electrical stimulation of the heart for the purpose of pacing (see pacemaker).
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