Labile Health Dictionary

Animal bites are best treated as puncture wounds and simply washed and dressed. In some cases ANTIBIOTICS may be given to minimise the risk of infection, together with TETANUS toxoid if appropriate. Should RABIES be a possibility, then further treatment must be considered. Bites and stings of venomous reptiles, amphibians, scorpions, snakes, spiders, insects and ?sh may result in clinical effects characteristic of that particular poisoning. In some cases speci?c ANTIVENOM may be administered to reduce morbidity and mortality.

Many snakes are non-venomous (e.g. pythons, garter snakes, king snakes, boa constrictors) but may still in?ict painful bites and cause local swelling. Most venomous snakes belong to the viper and cobra families and are common in Asia, Africa, Australia and South America. Victims of bites may experience various effects including swelling, PARALYSIS of the bitten area, blood-clotting defects, PALPITATION, respiratory di?culty, CONVULSIONS and other neurotoxic and cardiac effects. Victims should be treated as for SHOCK – that is, kept at rest, kept warm, and given oxygen if required but nothing by mouth. The bite site should be immobilised but a TOURNIQUET must not be used. All victims require prompt transfer to a medical facility. When appropriate and available, antivenoms should be administered as soon as possible.

Similar management is appropriate for bites and stings by spiders, scorpions, sea-snakes, venomous ?sh and other marine animals and insects.

Bites and stings in the UK The adder (Vipera berus) is the only venomous snake native to Britain; it is a timid animal that bites only when provoked. Fatal cases are rare, with only 14 deaths recorded in the UK since 1876, the last of these in 1975. Adder bites may result in marked swelling, weakness, collapse, shock, and in severe cases HYPOTENSION, non-speci?c changes in the electrocardiogram and peripheral leucocytosis. Victims of adder bites should be transferred to hospital even if asymptomatic, with the affected limb being immobilised and the bite site left alone. Local incisions, suction, tourniquets, ice packs or permanganate must not be used. Hospital management may include use of a speci?c antivenom, Zagreb®.

The weever ?sh is found in the coastal waters of the British Isles, Europe, the eastern Atlantic, and the Mediterranean Sea. It possesses venomous spines in its dorsal ?n. Stings and envenomation commonly occur when an individual treads on the ?sh. The victim may experience a localised but increasing pain over two hours. As the venom is heat-labile, immersion of the affected area in water at approximately 40 °C or as hot as can be tolerated for 30 minutes should ease the pain. Cold applications will worsen the discomfort. Simple ANALGESICS and ANTIHISTAMINE DRUGS may be given.

Bees, wasps and hornets are insects of the order Hymenoptera and the females possess stinging apparatus at the end of the abdomen. Stings may cause local pain and swelling but rarely cause severe toxicity. Anaphylactic (see ANAPHYLAXIS) reactions can occur in sensitive individuals; these may be fatal. Deaths caused by upper-airway blockage as a result of stings in the mouth or neck regions are reported. In victims of stings, the stinger should be removed as quickly as possible by ?icking, scraping or pulling. The site should be cleaned. Antihistamines and cold applications may bring relief. For anaphylactic reactions ADRENALINE, by intramuscular injection, may be required.... bites and stings

Low blood sugar. It can be an actual clinical condition (rather rare), but the term is usually applied to LABILE blood sugar, where the highs are socially acceptable, if zappy, but the lows cause headaches, depression...and sugar cravings...which only kick the sugars UP...which forces the sugars DOWN...etc. This is a subclinical condition that usually goes nowhere, at least clinically, but can drive you (or your companion) crazy. Some normal and healthy food have a rapid blood presence and can leave you hanging; fruits, potatoes and carrot juice are LOUSY...legumes, particularly beans, supply slow and extended release of calories...mostly because of high levels of soluble fiber...and laborious digestion. Even adding such dietarily useless items like Psyllium Seed and Chia Seed can do wonders to slow down sugar spiking.... hypoglycemia

Houtt.

Family: Myristicaceae.

Habitat: Native to the Moluccas Islands; grown in the Nilgiris, Kerala, Karnataka and West Bengal.

English: Nutmeg, Mace.

Ayurvedic: Jaatiphala, Jaatishasya, Maalatiphala (seed kernel).

Jaatipatri, Jaatipatra, Jaatipatraka, Jaatikosha (mace).

Unani: Jauzbuwaa (seed), Bisbaasaa (mace).

Siddha/Tamil: Jaathikkai, Saadikai (nutmeg); Saadippatthiri, Jaadip- patiri (mace).

Action: Nutmeg—carminative, spasmolytic, antiemetic, orexi- genic; topically anti-inflammatory. Mace—stimulant carminative. Narcotic in high doses.

Nutmeg is used in flatulency, diarrhoea, nausea and vomiting. Mace is used in rheumatism, chronic bowel complaints and asthma. When roasted, both nutmeg and mace are used for diarrhoea, colic, flatulence and dyspepsia.

Key application: Dried seed and aril—included among unapproved herbs by German Commission E. Following actions have been considered: antispasmodic, MAO inhibition, inhibition of prostaglandin synthesis.

The Ayurvedic Pharmacopoeia of India recommends the kernel of the fruit in spermatorrhoea.

An aqueous extract of nutmeg is reported to show anti-secretory activity against E. coli heat-labile enterotoxin; the hexane soluble fraction of the alcoholic extract inhibited the heat-labile and heat-stable-enterotoxin-induced secretory response in animal studies.

The hexane extract contains myris- ticin, an anti-inflammatory principle, and licarin-B and dehydro di- isoeugenol which exhibited CNS depressant properties. The extracts of nutmeg decreased kidney prostaglan- din levels in rats. They also inhibited platelet aggregation (due to eugenol and isoeugenol). The anti-inflammatory activity observed in carrage- enan-induced oedema in rats and enhanced vascular permeability in mice, are attributed to myristicin present in mace.

Mace also activates hepatic detoxification process. Monomeric and dimer- ic phenyl propanoids (myristicin, de- hydro diisoeugenol) from mace, on p.o. administration in mice, produced suppression of lipid peroxidation in liver.

Seeds contain about 0.24% myris- ticin, whereas volatile oil about 3.12%.

The resorcinols, malabaricones B and C, isolated from the seed coat (mace) exhibited strong antibacterial and antifungal activities. Neoplasm inhibitors, phenylpropyl derivatives, have been isolated from pulverized mace.

Dosage: Endosperm of dried seed (kernel of fruit)—0.5-1.0 g powder. (API, Vol. I.)... myristica fragrans

Also termed tetraiodothyronine, nicknamed is thyroxine. Secreted by the thyroid along with T3 (triiodothyronine...also called thyroxine), this thyroxine is mostly conjugated in the blood by TBG (thyroxine-binding globulin), whereas the more active T3 tends to float free. T4 is broken down to T3 and forms a stable feeder reserve, preventing rapid shifts in its more labile relative... t4