Leukoplakia Health Dictionary

See LEUKOPLAKIA.... leucoplakia

The mucous membrane of the mouth can indicate the health of the individual and internal organs. For example, pallor or pigmentation may indicate ANAEMIA, JAUNDICE or ADDISON’S DISEASE.

Thrush is characterised by the presence of white patches on the mucous membrane which bleeds if the patch is gently removed. It is caused by the growth of a parasitic mould known as Candida albicans. Antifungal agents usually suppress the growth of candida. Candidal in?ltration of the mucosa is often found in cancerous lesions.

Leukoplakia literally means a white patch. In the mouth it is often due to an area of thickened cells from the horny layer of the epithelium. It appears as a white patch of varying density and is often grooved by dense ?ssures. There are many causes, most of them of minor importance. It may be associated with smoking, SYPHILIS, chronic SEPSIS or trauma from a sharp tooth. Cancer must be excluded.

Stomatitis (in?ammation of the mouth) arises from the same causes as in?ammation elsewhere, but among the main causes are the cutting of teeth in children, sharp or broken teeth, excess alcohol, tobacco smoking and general ill-health. The mucous membrane becomes red, swollen and tender and ulcers may appear. Treatment consists mainly of preventing secondary infection supervening before the stomatitis has resolved. Antiseptic mouthwashes are usually su?cient.

Gingivitis (see TEETH, DISEASES OF) is in?ammation of the gum where it touches the tooth. It is caused by poor oral hygiene and is often associated with the production of calculus or tartar on the teeth. If it is neglected it will proceed to periodontal disease.

Ulcers of the mouth These are usually small and arise from a variety of causes. Aphthous ulcers are the most common; they last about ten days and usually heal without scarring. They may be associated with STRESS or DYSPEPSIA. There is no ideal treatment.

Herpetic ulcers (see HERPES SIMPLEX) are similar but usually there are many ulcers and the patient appears feverish and unwell. This condition is more common in children.

Calculus (a) Salivary: a calculus (stone) may develop in one of the major salivary-gland ducts. This may result in a blockage which will cause the gland to swell and be painful. It usually swells before a meal and then slowly subsides. The stone may be passed but often has to be removed in a minor operation. If the gland behind the calculus becomes infected, then an ABSCESS forms and, if this persists, the removal of the gland may be indicated. (b) Dental, also called TARTAR: this is a calci?ed material which adheres to the teeth; it often starts as the soft debris found on teeth which have not been well cleaned and is called plaque. If not removed, it will gradually destroy the periodontal membrane and result in the loss of the tooth. (See TEETH, DISORDERS OF.)

Ranula This is a cyst-like swelling found in the ?oor of the mouth. It is often caused by mild trauma to the salivary glands with the result that saliva collects in the cyst instead of discharging into the mouth. Surgery may be required.

Mumps is an acute infective disorder of the major salivary glands. It causes painful enlargement of the glands which lasts for about two weeks. (See also main entry for MUMPS.)

Tumours may occur in all parts of the mouth, and may be BENIGN or MALIGNANT. Benign tumours are common and may follow mild trauma or be an exaggerated response to irritation. Polyps are found in the cheeks and on the tongue and become a nuisance as they may be bitten frequently. They are easily excised.

A MUCOCOELE is found mainly in the lower lip.

An exostosis or bone outgrowth is often found in the mid line of the palate and on the inside of the mandible (bone of the lower jaw). This only requires removal if it becomes unduly large or pointed and easily ulcerated.

Malignant tumours within the mouth are often large before they are noticed, whereas those on the lips are usually seen early and are more easily treated. The cancer may arise from any of the tissues found in the mouth including epithelium, bone, salivary tissue and tooth-forming tissue remnants. Oral cancers represent about 5 per cent of all reported malignancies, and in England and Wales around 3,300 people are diagnosed annually as having cancer of the mouth and PHARYNX.

Cancer of the mouth is less common below the age of 40 years and is more common in men. It is often associated with chronic irritation from a broken tooth or ill-?tting denture. It is also more common in those who smoke and those who chew betel leaves. Leukoplakia (see above) may be a precursor of cancer. Spread of the cancer is by way of the lymph nodes in the neck. Early treatment by surgery, radiotherapy or chemotherapy will often be e?ective, except for the posterior of the tongue where the prognosis is very poor. Although surgery may be extensive and potentially mutilating, recent advances in repairing defects and grafting tissues from elsewhere have made treatment more acceptable to the patient.... mouth, diseases of

Acquired Immune Deficiency Syndrome. Infection by HIV virus may lead to AIDS, but is believed to be not the sole cause of the disease. It strikes by ravaging the body’s defence system, destroying natural immunity by invading the white blood cells and producing an excess of ‘suppressant’ cells. It savages the very cells that under normal circumstances would defend the body against the virus. Notifiable disease. Hospitalisation. AIDS does not kill. By lacking an effective body defence system a person usually dies from another infection such as a rare kind of pneumonia. There are long-term patients, more than ten years after infection with HIV who have not developed AIDS. There are some people on whom the virus appears to be ineffective. The HIV virus is transmitted by infected body fluids, e.g. semen, blood or by transfusion.

A number of co-factors are necessary for AIDS to develop: diet, environment, immoral lifestyle, drugs, etc also dispose to the disease which, when eliminated, suggest that AIDS needs not be fatal. However, there is no known cure. Smoking hastens onset. Causes include needle-sharing and sexual contacts. Also known as the ‘Gay Plague’ it can be transmitted from one member of the family to another non-sexual contact.

The virus kills off cells in the brain by inflammation, thus disposing to dementia.

Symptoms. Onset: brief fever with swollen glands. “Feeling mildly unwell”. This may pass off without incident until recurrence with persistent diarrhoea, night sweats, tender swollen lymph nodes, cough and shortness of breath. There follows weight loss, oral candida. Diagnosis is confirmed by appearance of ugly skin lesions known as Kaposi’s sarcoma – a malignant disease. First indication is the appearance of dark purple spots on the body followed by fungoid growths on mouth and throat.

While some cases of STDs have been effectively treated with phytotherapy, there is evidence to suggest it may be beneficial for a number of reasons. Whatever the treatment, frequent blood counts to monitor T-4 cells (an important part of the immune system) are necessary. While a phytotherapeutic regime may not cure, it is possible for patients to report feeling better emotionally and physically and to avoid some accompanying infections (candida etc).

Treatment. Without a blood test many HIV positives may remain ignorant of their condition for many years. STD clinics offer free testing and confidential counselling.

Modern phytotherapeutic treatment:–

1. Anti-virals. See entry.

2. Enhance immune function.

3. Nutrition: diet, food supplements.

4. Psychological counselling.

To strengthen body defences: Garlic, Echinacea, Lapacho, Sage, Chlorella, Reisha Mushroom, Shiitake Mushroom. Of primary importance is Liquorice: 2-4 grams daily.

Upper respiratory infection: Pleurisy root, Elecampane.

Liver breakdown: Blue Flag root, Milk Thistle, Goldenseal.

Diarrhoea: Bayberry, Mountain Grape, American Cranesbill, Slippery Elm, lactobacillus acidophilus.

Prostatitis: Saw Palmetto, Goldenrod, Echinacea.

Skin lesions: External:– Comfrey, Calendula or Aloe Vera cream.

To help prevent dementia: a common destructive symptom of the disease: agents rich in minerals – Alfalfa, Irish Moss, Ginkgo, St John’s Wort, Calcium supplements.

Nervous collapse: Gotu Kola, Siberian Ginseng, Oats, Damiana.

Ear Inflammation: Echinacea. External – Mullein ear drops.

With candida: Lapacho tea. Garlic inhibits candida.

Anal fissure: Comfrey cream or Aloe Vera gel (external).

Practitioner: Formula. Liquid extract Echinacea 30ml (viral infection) . . . Liquid extract Poke root 10ml (lymphatic system) . . . Liquid extract Blue Flag root 10ml (liver stimulant) . . . Tincture Goldenseal 2ml (inflamed mucous membranes) . . . Liquid extract Guaiacum 1ml (blood enricher) . . . Decoction of Sarsaparilla to 100ml. Sig: 5ml (3i) aq cal pc.

Gargle for sore throat: 5-10 drops Liquid extract or Tincture Echinacea to glass water, as freely as desired.

Abdominal Castor oil packs: claimed to enhance immune system.

Chinese medicine: Huang Qi (astragalus root).

Urethral and vaginal irrigation: 2 drops Tea Tree oil in strong decoction Marshmallow root: 2oz to 2 pints water. Inject warm.

Diet. Vitamin C-rich foods, Lecithin, Egg Yolk, Slippery Elm gruel, Red Beet root, Artichokes. Garlic is particularly indicated as an anti-infective.

Nutrition. Vitamin A is known to increase resistance by strengthening the cell membrane; preferably taken as beta carotene 300,000iu daily as massive doses of Vitamin A can be toxic. Amino acid – Glutathione: Garlic’s L-cysteine relates.

Vitamin C. “The virus is inactivated by this vitamin. Saturating cells infected with the HIV virus with the vitamin results in 99 per cent inactivation of the virus. The vitamin is an anti-viral and immune system modulator without unwanted side-effects. The ascorbate, when added to HIV cells, substantially reduced the virus’s activity without harming the cells at specific concentrations. Patients taking large doses report marked improvement in their condition. Minimum daily oral dose: 10 grams.” (Linus Pauling Institute, Science and Medicine, Palo Alto, California, USA)

Periwinkle. An anti-AIDS compound has been detected in the Madagascan Periwinkle (Catharanthus roseus), at the Chelsea Physic Garden.

Mulberry. The black Mulberry appears to inhibit the AIDS virus.

Hyssop. An AIDS patient improved to a point where ulcers were healed, blood infection eliminated, and Kaposi’s sarcoma started to clear when her mother gave her a traditional Jamaican tea made from Hyssop, Blessed Thistle and Senna. From test-tube research doctors found that Hyssopus officinalis could be effective in treatment of HIV/AIDS. (Medical Journal Antiviral Research, 1990, 14, 323-37) Circumcision. Studies have shown that uncircumcised African men were more than five to eight times more likely to contract AIDS than were circumcised men; life of the virus being short-lived in a dry environment. (Epidemiologist Thomas Quinn, in Science Magazine)

Study. A group of 13 HIV and AIDS patients received 200mg capsules daily of a combination of Chelidonium (Greater Celandine) 175mg; Sanguinaria (Blood root) 5mg; and Slippery Elm (Ulmus fulva) 20mg. More than half the patients enjoyed increased energy and improved immune function with reduction in both size and tenderness of lymph nodes. (D’Adamo P. ‘Chelidonium and Sanguinaria alkaloids as anti-HIV therapy. Journal of Naturopathic Medicine (USA) 3.31-34 1992)

Bastyr College of Naturopathy, Seattle, MA, USA. During 1991 the College carried out a study which claimed that a combination of natural therapies including nutrition, supplements, herbal medicine, hydrotherapy and counselling had successfully inhibited HIV and other viral activity in all patients in controlled trials lasting a year.

Patients chosen for the trial were HIV positive, not on anti-viral drugs and showing symptoms of a compromised immune system, but without frank AIDS (generally taken to be indicated by Karposi’s sarcoma and/or PCP-pneumocystitis carinii pneumonia).

Symptoms included: Lymphadenopathy in at least two sites, oral thrush, chronic diarrhoea, chronic sinusitis, leukoplakia, herpes, night sweats and fatigue.

Assessment was subjective and objective (including T-cell ratio tests). The patients did better than comparable groups in published trials using AZT.

Treatment was naturopathic and herbal. Patients receiving homoeopathy and acupuncture did not do as well as those receiving herbs.

Best results with herbs were: Liquorice (1g powder thrice daily); St John’s Wort (Yerba prima tablets, 3, on two days a week only). Patients reported a great increase in the sense of well-being on St John’s Wort. An equivalent dose of fresh plant tincture would be 10ml. The tincture should be of a good red colour. The College did not use Echinacea, which would stimulate the central immune system and which would therefore be contra-indicated.

Supplements given daily. Calcium ascorbate 3g+ (to bowel tolerance). Beta-carotene 300,000iu. Thymus gland extract tablets 6. Zinc 60mg (with some Copper). B-vitamins and EFAs.

To control specific symptoms: most useful herbs were: Tea Tree oil for fungal infections; Goldenseal and Gentian as bitters. Ephedra and Eyebright for sinusitis. Carob drinks for non-specific enteritis. Vitamin B12 and topical Liquorice for shingles.

Counselling and regular massage were used to maintain a positive spirit. Studies show all long term HIV positive survivors have a positive attitude and constantly work at empowering themselves.

Results showed significant improvements in symptoms suffered by HIV patients despite a slow deterioration in blood status. Methods used in the study had dramatically reduced mortality and morbidity. A conclusion was reached that AIDS may not be curable but it could be manageable. (Reported by Christopher Hedley MNIMH, London NW1 8JD, in Greenfiles Herbal Journal) ... aids

The most serious type of mouth cancer due to its rapid spread. It mainly affects people over 40 and is associated with smoking, heavy alcohol consumption, and poor oral hygiene. The edge of the tongue is most commonly affected. The first sign may be a small ulcer with a raised margin, a leukoplakia, a fissure, or a raised, hard mass.

Diagnosis of tongue cancer is made by a biopsy. Small tumours, especially those occurring at the tip of the tongue, are usually removed surgically. Larger tumours or those that have spread often require radiotherapy.... tongue cancer

n. an abnormal red patch of skin that occurs particularly in the mouth or on the genitalia and is precancerous. Erythroplasia of Queyrat is a nonkeratinizing *carcinoma in situ affecting the glans of the penis or the inner surface of the prepuce. It is ten times more likely to progress to invasive squamous cell carcinoma than is *Bowen’s disease of the penis. Compare leukoplakia.... erythroplasia

(qat, kat) n. the leaves of the shrub Catha edulis, which contain a stimulant. In Yemen these leaves are wrapped around betel nuts and chewed: this habit is associated with the development of oral *leukoplakia. In 2014 khat became a class-C drug in the UK owing to its increasing use. Possession of the drug can result in up to two years in prison and an unlimited fine.... khat

adj. describing a nonmalignant condition that is known to become malignant if left untreated. *Leukoplakia of the vulva is known to be a precancerous condition. See also metaplasia.... precancerous

Huckleberry. Vaccinum myrtillus L. French: Petit Myrte. German: Echte Heidelbeere. Italian: Baceri mirtillo. Fresh berries, rarely leaves.

Action. Anti-inflammatory, anti-diarrhoeal, antemetic, astringent, diuretic, refrigerant, strengthens blood vessels, vein tonic. Inhibits growth of certain bacteria. Contains Vitamins A, C, P. Gather before fruit ripens.

Uses: Dropsy, gravel, violent irritable bowel, diverticulosis, nausea or vomiting, sore throat (gargle), leucorrhoea (douche), scurvy, Vitamin C deficiency. Popular in Russian Folk Medicine for gastro- enteritis and to reduce insulin intake in diabetes. Cleansing wash for old ulcers (decoction). Pharyngitis (gargle). Leukoplakia of the mouth, vagina and urethra – improvement reported. Crohn’s disease. Bacillus Coli infections. By stimulating production of visual purple improves vision, especially night vision. Varicose veins. Piles. Cystitis.

Preparations: Thrice daily.

Decoction: 1oz to 1 pint water, remove vessel when boiling point is reached. Wineglass freely.

Liquid Extract, dose: 2-8ml.

Home tincture. Handful bilberries to 1 pint Vodka. Cork or cap. Shake daily for 1 week. Filter. Wineglass freely.

Formula. Combines well with Meadowsweet and Horsetail (equal parts).

Powder, capsules: 280mg. 2 capsules thrice daily between meals. (Arkocaps)

Diet. Cooked fresh berries are a popular dessert. Equal parts leaves of Wild Strawberry, Thyme and Bilberry substitute for domestic tea.

Fresh berries. Chew 1-3 teaspoons daily. ... bilberry

Forms of cancerous tumour that affect the lips, tongue, and oral cavity. Lip cancer and tongue cancer are the most common types.

Predisposing causes of mouth cancer are poor oral hygiene, drinking alcoholic spirits, tobacco-smoking, chewing tobacco, and inhaling snuff. Irritation from ill-fitting dentures or jagged teeth are other factors. Men are affected twice as often as women; most cases occur in men over the age of 40.

Mouth cancer usually begins with a whitish patch, called leukoplakia, or a small lump. These may cause a burning sensation, but are usually painless. As the tumour grows, it may develop into an ulcer or a deep fissure, which may bleed and erode surrounding tissue.

Diagnosis is based on a biopsy. Treatment consists of surgery, radiotherapy, or both. Extensive surgery may cause facial disfigurement and problems with eating and speaking, which may require reconstructive surgery. Radiotherapy sometimes damages the salivary glands (see mouth, dry).

When mouth cancer is detected and treated early, the outlook is good.... mouth cancer