causing lipolysis, the chemical disintegration or splitting of fats.
Habitat: The sub-tropical Himalayas of Kumaon and Nepal; cultivated in Andhra Pradesh.
Ayurvedic: Gandira (Achyranthes aquatica Br. is also equated with Gandira). (Doubtful synonym.)Folk: Garmar (Gujarat), Gurmal.Action: Root and leaf—spasmolytic, antithrombotic, anti-inflammatory, lipolytic.
In experimental amoebiasis of rats, the root powder and ethanolic extract showed amoebicidal activity against Entamoeba histolytica.An alcoholic extract of the roots and essential oil from it, were found to inhibit passive cutaneous anaphylaxis in the mouse and rat.The plant produces the labdane diterpenoid, forskolin in its tuberous roots.Forskolin was discovered during a screening of medicinal plants by Central Drug Research Institute, Luc- know, India, in 1974. (Planta Medica, 1985, 51, 473-477.) The screening revealed the presence of a hypoten- sive and spasmolytic principle, named coleonol (later the name was changed to forskolin). The basic mechanism of forskolin is the activation of an enzyme, adenylate cyclase, which increases the amount of cyclic adeno- sine monophosphate (cAMP) in cells. Raised intracellular cAMP level exhibits following physiological effects : inhibition of platelet activation and degranulation; inhibition of mast cell degranualation and histamine release; relaxation of the arteries and other smooth muscles; increased insulin secretion; increased thyroid function; increased lipolysis.Forskolin, in clinical studies, reduced intraocular pressure when it was applied to the eyes for treating glaucoma. It has been shown to be a direct cerebral vasodilator. It has also been studied as a possible bron- chodilator (in the treatment of asthma) and has been shown to effectively reverse methacholine-induced broncho constriction in extrinsic asthmatics.Standardized Coleus extracts containing forskolin (18% in 50 mg) find application in weight-loss programmes. (Michael T. Murray.)Studies on forskolin and some 50 derivatives of the compound indicate that the natural product is more active than the analogs prepared from it.The wild var. is known as Kaffir Potato.... coleus barbatusHabitat: Throughout India, as a weed upto 2,000 m.
English: Nut Grass.Ayurvedic: Musta, Mustaa, Mus- taka, Abda, Ambuda, Ambhoda, Ambodhara, Bhadra, Bhadraa, Bhadramusta, Bhadramustaa, Bhadramustaka, Ghana, Jalada, Jaldhara, Meghaahvaa, Nirada, Vaarida, Vaarivaaha, Payoda, Balaahaka. Ganda-Duurvaa (var.).Unani: Naagarmothaa, Saad-e-Kufi.Siddha/Tamil: Koraikkizhangu.Folk: Mothaa.Action: Carminative, astringent, anti-inflammatory, antirheumat- ic, hepatoprotective, diuretic, antipyretic, analgesic, hypoten- sive, emmenagogue and nervine tonic.
Used for intestinal problems, indigestion, sprue, diarrhoea, dysentery, vomiting and fever; also as a hypoc- holesterolaemic drug and in obesity.Along with other therapeutic applications, The Ayurvedic Pharmacopoeia of India indicated the use of the rhizome in rheumatism, inflammations, dysuria, puerperal diseases and obesity.The tuber is rich in Cu, Fe, Mg and Ni. Beta-sitosterol, isolated from the tubers, exhibits significant anti- inflammatory activity against carra- geenan- and cotton pellet-induced oedema in rats; the activity is comparable to hydrocortisone and phenylbutazone when administered intraperi- toneally.The alcoholic and aqueous extracts of the tubers possess lipolytic action and reduce obesity by releasing enhanced concentrations of biogenic amines from nerve terminals of the brain which suppress the appetite centre. Presence of eudalne group of ses- quiterpenic compounds of sesquiter- pene alcohol, isocyperol is said to play an important role in lipid metabolism.An alcoholic extract of the plant exhibits liver-protective activity against CCL4-induced liver damage in mice.Methanolic extract of the plant stimulates the production of melanin in cultured melanocytes. (Plant extract is used in preparations used for pigmentation of skin and hair, also in suntan gels.) Aqueous-alcoholic extract of the tuber exhibited hypotensive, diuretic, antipyretic and analgesic activities. These are attributed to a triterpenoid.The essential oil (0.5-0.9%) from the tubers contains mainly sesquiterpenes.C. platystilis Br. is equated with Kaivarta-mustaka.Dosage: Rhizome—3-6 g powder; 20-30 ml decoction. (API Vol. III.)... cyperus rotundusHabitat: Native to South America; cultivated in some Indian gardens. In northern India, grows in Lucknow.
English: Mate Tea, Yerba Mate. Paraguay Tea.Action: Stimulant to brain and nervous system, mild antispasmod- ic, eliminates uric acid. Used for physical exhaustion, rheumatism, gout and nervous headache. (A national drink of Paraguay and Brazil.) Causes purging and even vomiting in large doses.
Key application: In physical and mental fatigue. (German Commission E, WHO.) In fatigue, nervous depression, psychogenic headache especially from fatigue, rheumatic pains. (The British Herbal Pharmacopoeia.) German Commission E reported analeptic, positively inotropic, positively chronotropic, glycogenolytic, lipolytic and diuretic properties.The leaves contain xanthine derivatives, including caffeine (0.2-2%), theobromine (0.3-00.5%), theophylline (absent in some samples), polyphe- nolics, tannins and chlorogenic acid, vanillin, vitamin C, volatile oil. Used in the same way as tea, due to its caffeine and theobromine content.Mate is a world famous tea and is commonly consumed in several South American countries.The flavour constituents exhibited moderate to weak broad-spectrum antimicrobial activity against several Gram-positive bacteria. Some components are bactericidal, particularly against the most carcinogenic bacteria, Streptococcus mutans.... ilex paraguariensisHabitat: Cultivated chiefly in Andhra Pradesh, Maharashtra, Karnataka, and Orissa.
English: Castor seed.Ayurvedic: Eranda, Chitra- bija, Triputi; Tribija, Vaataari, Chanchu, Manda, Uruvaka, Gandharva-hastaa, Panchaan- gula, Vardhamaana, Uttaanpatraka, Vyaaghrapuchha, Chitraa.Unani: Bedanjeer, Arand.Siddha/Tamil: Ammanakku.Action: Oil from seeds and young leaf—purgative. Oil is used in dermatosis and eczema. Leaves— used as poultice to extract the worm.
Root—a decoction is administered for lumbago and allied complaints.Bark—purgative.The Ayurvedic Pharmacopoeia ofIn- dia recommends the decoction of the dried, mature root in rheumatism, pain in the urinary bladder, lumbago, diseases of the abdomen and inflammations; fresh leaf in helminthiasis, dysu- ria, arthritis, pain in the urinary bladder, dysuria, abscesses; dried seed powder in constipation, rheumatism, diseases of the liver and spleen, piles, lumbago, sciatica.The root extract exhibited significant anti-inflammatory activity against carrageenan-, bradykinin-, 5-HT-and dextran-induced rat hind paw oedema. N-Demethylricinine showed dose-dependent anticholestatic and hepato- protective activities in rats.Castor oil, derived from the seeds, is a well-known purgative (dose 520 ml).Castor seed contains toxic components (2.8-3.0% on whole seed; about 10% in the flour) which are highly poisonous to human beings and animals. The principal toxic substance is the albumin, ricin. Allergens and a feebly toxic alkaloid ricinine is also present. An ulcerative factor in the seed is reported. Like other toxalbumins, ricin agglutinizes the mammalian red bleed corpuscles. (Ricin loses its toxicity and antigenic action on treatment with potassium permanganate.)Castor oil consists principally of ri- cinoleic acid. Stearic, oleic, linoleic and dihydroxystearic acids are present in small amounts. The strong laxative property of castor oil is reported due to the local irritant action caused in the intestines by ricinoleic acid formed by hydrolysis under the influence of lipolytic enzymes. (The oil should not be used with fat-soluble vermifuge, it may increase its absorption and toxic- ity.)Dosage: Root—20-30 g for decoction. (API, Vol. I.) Leaf—10- 20 ml juice; 2-5 g powder; seed— 0.5-3 g powder. (API, Vol. III.)... ricinus communisFAMILY: Apiaceae (Umbelliferae)
SYNONYMS: Coriander seed, Chinese parsley.
GENERAL DESCRIPTION: A strongly aromatic annual herb about 1 metre high with bright green delicate leaves, umbels of lacelike white flowers, followed by a mass of green (turning brown) round seeds.
DISTRIBUTION: Native to Europe and western Asia; naturalized in North America. Cultivated throughout the world, the oil is mainly produced in the USSR, Yugoslavia and Romania.
OTHER SPECIES: Various chemotypes of the same species are found according to geographical location.
HERBAL/FOLK TRADITION: A herb with a long history of use the seeds were found in the ancient Egyptian tomb of Rameses 11. The seeds and leaves are widely used as a garnish and domestic spice, especially in curries. It has been used therapeutically, mainly in the form of an infusion for children’s diarrhoea, digestive upsets, griping pains, anorexia and flatulence.
In Chinese medicine the whole herb is used for dysentery, piles, measles, nausea, toothache and for painful hernia.
ACTIONS: Analgesic, aperitif, aphrodisiac, antioxidant, antirheumatic, antispasmodic, bactericidal, depurative, digestive, carminative, cytotoxic, fungicidal, larvicidal, lipolytic, revitalizing, stimulant (cardiac, circulatory, nervous system), stomachic.
EXTRACTION: Essential oil by steam distillation from the crushed ripe seeds. (An essential oil is also produced by steam distillation from the fresh and dried leaves, which contains a high proportion of decylaldehyde.)
CHARACTERISTICS: A colourless to pale yellow liquid with a sweet, woody-spicy, slightly musky fragrance. It blends well with clary sage, bergamot, jasmine, olibanum, neroli, petitgrain, citronella, sandalwood, cypress, pine, ginger, cinnamon and other spice oils.
PRINCIPAL CONSTITUENTS: Mainly linalol (55–75 per cent), decylaldehyde, borneol, geraniol, carvone, anethole, among others; constituents; vary according to source.
SAFETY DATA: Generally non-toxic, non irritant, non-sensitizing. Stupefying in large doses – use in moderation.
AROMATHERAPY/HOME: USE
Circulation, Muscles And Joints:
Accumulation of fluids or toxins, arthritis, gout, muscular aches and pains, poor circulation, rheumatism, stiffness.
Digestive System: Anorexia, colic, diarrhoea, dyspepsia, flatulence, nausea, piles, spasm.
Immune System: Colds, ’flu, infections (general), measles.
Nervous System: Debility, migraine, neuralgia, nervous exhaustion.
OTHER USES: Used as a flavouring agent in pharmaceutical preparations, especially digestive remedies. Used as a fragrance component in soaps, toiletries and perfumes. Employed by the food industry especially in meat products and to flavour liqueurs such as Chartreuse and Benedictine; also used for flavouring tobacco.... coriander
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