A form of the tropical parasitic disease filariasis, which is caused by an infestation by the worm LOA LOA. The worms travel beneath the skin, producing itchy areas of inflammation known as Calabar swellings, and can sometimes be seen moving across the front of the eye. Loiasis is treated with a course of diethylcarbamazine.
Loiasis is the disease caused by the ?larial worm Loa loa, a thread-like worm which di?ers from
W. bancrofti in that it is shorter and thicker, and is found in the bloodstream during the day, not at night. It is transmitted by the mango ?y, Chrysops dimidiata, but other ?ies of this genus can also transmit it. It is con?ned to West and Central Africa. The characteristic feature of the disease is the appearance of fugitive swellings which may arise anywhere in the body in the course of the worm’s migration through it: these are known as Calabar swellings. The worm is often found in the eye, hence the old name of the worm in Africa – the eye worm. Diethylcarbamazine is the treatment for this form of FILARIASIS.
n. a disease, occurring in West and Central Africa, caused by the eye worm *Loa loa. The adult worms live and migrate within the skin tissues, causing the appearance of transitory calabar swellings. These are probably an allergic reaction to the worms’ waste products, and they sometimes lead to fever and itching. Worms often migrate across the eyeball just beneath the conjunctiva, where they cause irritation and congestion. Loiasis is treated with *diethylcarbamazine, which kills both the adults and larval forms.
n. a genus of bloodsucking flies, commonly called deer flies. Female flies, found in shady wooded areas, bite humans during the day. Certain species in Africa may transmit the tropical disease *loiasis to humans. In the USA C. discalis is a vector of *tularaemia.... chrysops
n. an anthelmintic drug that destroys filariae and is therefore used in the treatment of filariasis and loiasis. Side-effects may include headache, malaise, joint pains, nausea, and vomiting.... diethylcarbamazine