Loop diuretics Health Dictionary

Loop Diuretics: From 1 Different Sources


Drugs used in pulmonary oedema (excess ?uid in the lungs) caused by failure of the left VENTRICLE of the HEART. DIURETICS cause an increase in excretion of URINE, thus reducing the amount of ?uid in the body. Intravenous administration of loop diuretics relieves patients’ breathlessness. They work by inhibiting resorption of ?uid in the renal tubule loops of the KIDNEYS. Frusemide and bumetanide are commonly used loop diuretic drugs that act quickly and last for six hours so that they can be given twice in 24 hours without disturbing the patient’s sleep.
Health Source: Medical Dictionary
Author: Health Dictionary

Blind Loop Syndrome

A disorder in which abnormal FAECES occur as a result of a redundant loop in the small INTESTINE. The loop obstructs the normal ?ow of the contents of the bowel, causing stagnation. The syndrome is characterised by light-yellow, smelly, fatty, bulky faeces. The patient suffers from tiredness, malaise and loss of weight. Previous abdominal surgery is sometimes the cause, but the condition can be inherited. Blockage of intestinal contents upsets the bowel’s normal bacterial balance and hinders the normal absorption of nutrients. Treatment is either with antibiotics or, if that fails, surgery.... blind loop syndrome

Diuretics

Substances which increase urine and solute production by the KIDNEYS. They are used in the treatment of heart failure, HYPERTENSION, and sometimes for ASCITES secondary to liver failure. They may work by extra-renal or renal mechanisms.

The potential side-effects of diuretics are HYPOKALAEMIA, DEHYDRATION, and GOUT (in susceptible individuals).

Extra-renal mechanisms (a) Inhibiting release of antidiuretic hormone (e.g. water, alcohol); (b) increased renal blood ?ow (e.g. dopamine in renal doses).

Renal mechanisms (a) Osmotic diuretics act by ‘holding’ water in the renal tubules and preventing its reabsorption (e.g. mannitol); (b) loop diuretics prevent sodium, and therefore water, reabsorption (e.g. FRUSEMIDE); (c) drugs acting on the cortical segment of the Loop of Henle prevent sodium reabsorption, but are ‘weaker’ than loop diuretics (e.g. THIAZIDES); (d) drugs acting on the distal tubule prevent sodium reabsorption by retaining potassium

(e.g. spironalactone).... diuretics

Henle, Loop Of

That part of the nephron (see KIDNEYS) between the proximal and distal convoluted tubules. It extends into the renal medulla as a hairpin-shaped loop. The ascending link of the loop actively transports sodium from the lumen of the tube to the interstitium, and this, combined with the ‘counter-current’ ?ow of ?uid through the two limbs of the loop, plays a part in concentrating the urine.... henle, loop of

Henle’s Loop

the part of a kidney tubule that forms a loop extending towards the centre of the kidney. It is surrounded by blood capillaries, which absorb water and selected soluble substances back into the bloodstream. [F. G. J. Henle (1809–85), German anatomist]... henle’s loop

Implantable Loop Recorder

(ILR) a device, inserted beneath the skin of the chest, to record the heart rhythm for up to two years. It is usually used for the investigation of patients presenting with infrequent syncope (fainting) in whom arrhythmia is the suspected cause. When syncope occurs, the device can be examined using wireless technology to reveal the heart rhythm at the time of the episode.... implantable loop recorder

Induction Loop System

(loop system) a device for helping people with some types of *hearing aid or *cochlear implant to hear more effectively in certain situations. Electrical signals from a television, sound system, or microphone are passed through an amplifier to a wire that is positioned in a loop encompassing the desired listening area. This creates an electromagnetic field that can be picked up by a coil within the hearing aid or cochlear implant. Induction loops are installed in such places as public buildings, lecture theatres, classrooms, and churches. See also assistive listening device.... induction loop system

Loop

n. 1. a bend in a tubular organ, e.g. *Henle’s loop in a kidney tubule. 2. one of the patterns of dermal ridges in *fingerprints.... loop

Loop System

see induction loop system.... loop system

Negative Feedback Loop

a physiological loop for the control of hormone production by a gland. High levels of a circulating hormone act to reduce production of the releasing factors triggering its own production, i.e. they have a negative *feedback on these trigger factors. As circulating levels of the hormone fall, the negative feedback is reduced and the releasing factor starts to be produced again, allowing the hormone level to rise again.... negative feedback loop

Stagnant Loop Syndrome

see blind loop syndrome.... stagnant loop syndrome



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