Habitat: Cultivated throughout greater parts of India.
English: Smooth Luffa, Sponge- gourd, sponge Cucumber.Ayurvedic: Dhaamaargava, Ma- haakoshtaki, Mahaajaalini, Raa- jakoshataki.Siddha/Tamil: Mozhukupeerankai, Pikku.Action: Plant—used against pharyngitis, rhinitis, mastitis, oedema, swellings and burns. Leaves— used for chronic bronchitis. Leaf juice is given for amenorrhoea. Flowers—used for treating migraine. Seeds—alcoholic extract exhibited 9.80% fungitoxic activity.
German Commission E included Luffa aegyptiaca among unapproved herbs. Preparations of Luffa sponge, used as a preventive for infections or cold, as a remedy for colds, nasal catarrh as well as sinusitis and suppuration of the sinus, have been negatively evaluated.The saponins isolated from aerial parts are effective in controlling obesity, also the side-effects of steroids.The oleanane saponins, lucyoside AH (at least one component) is effective in preventing loss of hair.Spongegourd extracts or saponins (ginsenosides and lucyosides) find application in topical medication for skin disorders and haemorrhoids. Lucyo- sides are also used as antitussive.The roots of the mature plants contain an acidic pentacyclic triterpene, bryonolic acid. Bryonolic acid showed antiallergic and anti-inflammatory activity in experimental animals. An aqueous extract of seeds showed strong fibrinolytic activity. It also showed anticancer activity in transplanted tumours.Dosage: Leaf, flower, fruit—10- 20 ml juice. (CCRAS.)