Action: Fruit rind—used in rickets and enlargement of spleen, in skeletal fractures.
The plant contains iso-prenylated polyphenols—cambogin and cambo- ginol. The fruit contains about 30% acid (dry weight basis), which is essentially (-)-hydroxycitric acid (HCA). HCA is a potent inhibitor of ATP citrate lyase, the enzyme that produces acetyl CoA for both fatty acid and cholesterol synthesis.Taking Garcinia fruit rind extract orally does not seem to help decrease weight, satiety, fat oxidation or energy expenditure in obese people. Some researchers are of the view that garcinia inhibits the supply of fatty acids without affecting adipose conversion. (Natural Medicines Comprehensive Database, 2007.)Latex gave benzophenone derivatives, camboginol and cambogin.... garcinia cambogia
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