Lympho Health Dictionary

Lympho: From 1 Different Sources


Lymphoma

A neoplasia of the lymph tissue, such as Hodgkin’s Disease. Although it is frequently useful to stimulate immunity when a person is undergoing chemotherapy for cancer, since the resultant immunosuppression is a major side effect of the treatment, in lymphatic cancer this the POINT of the therapy...let it be.... lymphoma

Lymphoedema

Swelling of a part or organ due to obstruction to the LYMPH vessels draining it.... lymphoedema

Lymphosarcoma

A traditional term for non-Hodgkin’s lymphoma (see LYMPHOMA).... lymphosarcoma

Lymphocyte

A variety of white blood cell produced in the LYMPHOID TISSUE and lymphatic glands (see LYMPHATICS; GLAND) of the body. It contains a simple, rounded nucleus surrounded by protoplasm generally described as non-granular. Two varieties of lymphocyte are described, small and large, and together they form over 20 per cent of the white cells of the blood. They play an important part in the production of ANTIBODIES, and in the rejection of transplanted organs such as the heart (see TRANSPLANTATION). This they do in two di?erent ways: what are known as B-lymphocytes produce antibodies, while T-lymphocytes attack and destroy antigens (see ANTIGEN) directly. The latter are known as T-lymphocytes because they are produced by the THYMUS GLAND. Their numbers are increased in TUBERCULOSIS and certain other diseases. Such an increase is known as LYMPHOCYTOSIS.... lymphocyte

Lymphogranuloma Venereum

(LGV) A tropical sexually transmitted disease caused by Chlamydia trachomatis serotypes L1, L2 and L3.... lymphogranuloma venereum

Burkitt’s Lymphoma

Lymphoid tumour associated with Epstein-Barr (EB) virus. Especially common in malaria endemic areas, such as Africa and Papua New Guinea. May be associated with the immunosuppressive effects of the malaria infection.... burkitt’s lymphoma

Lymphocytosis

An increase in the number of lymphocytes in the blood (see LYMPHOCYTE) – for example, in response to viral infection or in chronic lymphocytic LEUKAEMIA.... lymphocytosis

Lymphoid Tissue

Tissue involved in the formation of LYMPH, lymphocytes (see LYMPHOCYTE), and ANTIBODIES. It consists of the LYMPH NODES, THYMUS GLAND, TONSILS and SPLEEN.... lymphoid tissue

T-lymphocyte

See LYMPHOCYTE.... t-lymphocyte

Burkitt’s Lymphoma

A cancer of lymph tissues that is characterized by tumours within the jaw and/or abdomen. It is confined almost exclusively to children living in low-lying, moist, tropical regions of Africa and New Guinea. Anticancer drugs or radiotherapy give complete or partial cure in about 80 per cent of cases. (See also lymphoma.)... burkitt’s lymphoma

B-lymphocyte (or B-cell)

A type of white blood cell that circulates through the body and is able to detect the presence of the foreign agents. Once exposed to an antigen on the agent, these cells differentiate into plasma cells to produce antibody.... b-lymphocyte (or b-cell)

Lymphogranuloma Inguinale

A venereal disease in which the chief characteristic is enlargement of glands in the groin – the infecting agent being a virus.... lymphogranuloma inguinale

Lymphokines

Lymphokines are polypeptides that are produced by lymphocytes (see LYMPHOCYTE) as part of their immune response to an ANTIGEN; their function is to communicate with other cells of the immune system (see IMMUNITY). Some lymphokines stimulate B-cells to di?erentiate into antibody-producing plasma cells; others stimulate T-lymphocytes to proliferate; other lymphokines become interferons (see INTERFERON).... lymphokines

Malignant Lymphoma

See LYMPHOMA.... malignant lymphoma

Non-hodgkin’s Lymphoma

See LYMPHOMA.... non-hodgkin’s lymphoma

T-cell Lymphoma

See LYMPHOMA.... t-cell lymphoma

T-lymphocytes (or T-cells)

White blood cells that have matured in the thymus gland. There are at least two kinds of T-lymphocytes - helpers and suppressors. In AIDS, the number of helper cells is decreased.... t-lymphocytes (or t-cells)

Lymphogranuloma Venereum (lgv)

Treatment: same as for Gonorrhoea. ... lymphogranuloma venereum (lgv)

Leukaemia, Chronic Lymphocytic

A type of leukaemia caused by proliferation of mature lymphocytes. Although it is incurable, the disease is not always fatal. The cause is unknown.

Symptoms develop slowly, often over many years. As well as symptoms and signs common to acute forms of leukaemia (see leukaemia, acute), there may be enlargement of the liver and spleen, persistent raised temperature, and night sweats. Diagnosis is by blood tests and a bone marrow biopsy. In many mild cases, no treatment is needed. To treat severe cases, anticancer drugs are given, sometimes with radiotherapy.... leukaemia, chronic lymphocytic

B Lymphocyte

n. see lymphocyte.... b lymphocyte

Cutaneous T-cell Lymphoma

a group of lymphomas in which abnormal T *lymphocytes are concentrated in the skin. The most common form is *mycosis fungoides.... cutaneous t-cell lymphoma

Lymphoblast

n. an abnormal cell present in the blood and the blood-forming organs in one type of leukaemia (lymphoblastic leukaemia). It has a large nucleus with very scanty cytoplasm and is thought to be the precursor of the lymphocyte. —lymphoblastic adj.... lymphoblast

Lymphoma, Non-hodgkin’s

Any cancer of lymphoid tissue (found mainly in the lymph nodes and spleen) other than Hodgkin’s disease. In most cases there is no known cause. Occasionally, the disease is associated with suppression of the immune system, particularly after an organ transplant. One type of nonHodgkin’s lymphoma, known as Burkitt’s lymphoma, is thought to be caused by the Epstein–Barr virus.

There is usually painless swelling of lymph nodes in the neck or groin. The liver and spleen may enlarge, and lymphoid tissue in the abdomen may be affected. Many other organs may become involved, leading to diverse symptoms ranging from headache to skin ulceration. Unless it is controlled, the disease (often marked by fever) progressively impairs the immune system, leading to death from infections or an uncontrolled spread of cancer. Diagnosis is based on a biopsy, usually taken from a lymph node. Chest X-ray, CT scanning, MRI, bone marrow biopsy, and lymphangiography of the abdomen may be needed to assess the extent of the disease.

If the lymphoma is confined to a single group of lymph nodes, treatment consists of radiotherapy. More often, the disease is more extensive, and in such cases anticancer drugs are given. A bone marrow transplant, together with drug treatment and/or radiotherapy, may be performed on some people.... lymphoma, non-hodgkin’s

Lymphocele

(lymphocoele) n. a collection of lymph in the tissues, which follows injury to, or operations upon, lymph nodes or ducts.... lymphocele

Lymphocytopenia

n. see lymphopenia.... lymphocytopenia

Lymphography

n. see lymphangiography.... lymphography

Lymphokine

n. a substance produced by lymphocytes that has effects on other cells involved in the immune system (see cytokines). An example is *interleukin 2 (IL-2).... lymphokine

Lymphopenia

(lymphocytopenia) n. a decrease in the number of *lymphocytes in the blood, which may occur in a wide variety of diseases.... lymphopenia

Lymphoplasmacytic Lymphoma

see Waldenstrom’s macroglobulinaemia.... lymphoplasmacytic lymphoma

Lymphopoiesis

n. the process of the production of *lymphocytes, which occurs in the *bone marrow as well as in the lymph nodes, spleen, thymus gland, and gut wall. The precursor cell from which lymphocytes are derived has not yet been identified.... lymphopoiesis

Lymphorrhagia

n. the escape of the lymph from lymphatic vessels that have been injured.... lymphorrhagia

Lymphoscintigraphy

n. an imaging scan undertaken to identify the *sentinel lymph nodes, which receive lymph drainage from a tumour and are the first to show evidence of metastasis, and to differentiate these from disease-free nodes; this is in order to plan treatment options, particularly for melanoma and breast cancer management.... lymphoscintigraphy

Lymphotoxin

n. a *lymphokine that lyses various cell types, including tumour cells.... lymphotoxin

Lymphovascular Invasion

the spread of cancer cells into lymphatic or blood vessels noted on histopathological analysis of a specimen taken at biopsy or after surgical resection. It is associated with a higher risk of lymph node involvement and distant metastases.... lymphovascular invasion

Non-hodgkin’s Lymphoma

see lymphoma.... non-hodgkin’s lymphoma

Tumour-infiltrating Lymphocyte

(TIL) a lymphoid cell that can infiltrate solid tumours. Such cells can be cultured in vitro, in the presence of *interleukin 2, and have been used as vehicles for *tumour necrosis factor in gene therapy trials for cancer.... tumour-infiltrating lymphocyte

X-linked Lymphoproliferative Syndrome

(XLP syndrome, Duncan’s disease) a hereditary disorder of the immune system caused by a defective *sex-linked gene carried on an *X chromosome. There is uncontrolled proliferation of B-*lymphocytes in response to infection by the Epstein-Barr virus, which can lead to fulminating hepatitis or lymphoma. This condition is due to a defect in a gene, SAP, which encodes a signalling molecule found in the cytoplasm of cells.... x-linked lymphoproliferative syndrome



Recent Searches