A skin rash that is made up of macules (discoloration of the skin) and papules (raised abnormalities of the skin).
adj. describing a rash that consists of both *macules and *papules.
n. a condition caused by *mast cell proliferation due to KIT *proto-oncogene mutations. It most commonly manifests in the skin but also affects other organs. Maculopapular variants were formerly known as urticaria pigmentosa. Systemic involvement is common in adult cases, with bone marrow examination essential for accurate diagnosis. It may be associated with haematological abnormalities, including leukaemias. Resolution is common in children with skin involvement only. Treatment includes antihistamines, mast-cell stabilizers (such as sodium *cromoglicate), and *tyrosine kinase inhibitors.... mastocytosis
(roseola infantum, exanthem subitum) n. a condition of young children in which a fever lasting for three or four days is followed by a rose-coloured maculopapular rash that fades after two days. The commonest exanthematous fever in young children, it is caused by human herpesvirus 6.... roseola