Magnesium is a light metallic element; it is one of the essential mineral elements of the body, without which the body cannot function properly. The adult body contains around 25 grams of magnesium, the greater part of which is in the bones. More than two-thirds of our daily supply comes from cereals and vegetables; as most other foods also contain useful amounts, there is seldom any di?culty in maintaining an adequate amount in the body. Magnesium is also an essential constituent of several vital enzymes (see ENZYME). De?ciency leads to muscular weakness and interferes with the e?cient working of the heart. The salts of magnesium used as drugs are the hydroxide of magnesium, the oxide of magnesium – generally known as ‘magnesia’ – and the carbonate of magnesium, all of which have an antacid action; also the sulphate of magnesium known as ‘Epsom salts’, which acts as a purgative.
Uses Compounds of magnesia are used to correct hyperacidity of the stomach and as a laxative (see LAXATIVES).... magnesium
A white powder with mild antacid properties (see ANTACIDS) and a prolonged action, it is used for treating peptic ulceration – commonly combined with quickly acting antacids. It has a mild laxative e?ect (see LAXATIVES).... magnesium trisilicate
A drug widely used in the PROPHYLAXIS treatment of certain forms of MENTAL ILLNESS. The drug should be given only on specialist advice. The major indication for its use is acute MANIA; it induces improvement or remission in over 70 per cent of such patients. In addition, it is e?ective in the treatment of manic-depressive patients (see MANIC DEPRESSION), preventing both the manic and the depressive episodes. There is also evidence that it lessens aggression in prisoners who behave antisocially and in patients with learning diffculties who mutilate themselves and have temper tantrums.
Because of its possible toxic effects – including kidney damage – lithium must only be administered under medical supervision and with monitoring of the blood levels, as the gap between therapeutic and toxic concentrations is narrow. Due to the risk of its damaging the unborn child, it should not be prescribed, unless absolutely necessary, during pregnancy – particularly not in the ?rst three months. Mothers should not take it while breast feeding, as it is excreted in the milk in high concentrations. The drug should not be taken with DIURETICS.... lithium carbonate
a magnesium salt used as an osmotic *laxative to treat constipation. It is also combined with *aluminium hydroxide in antacid preparations.... magnesium hydroxide
Health Encyclopedia