Malignant lymphoma Health Dictionary

A neoplasia of the lymph tissue, such as Hodgkin’s Disease. Although it is frequently useful to stimulate immunity when a person is undergoing chemotherapy for cancer, since the resultant immunosuppression is a major side effect of the treatment, in lymphatic cancer this the POINT of the therapy...let it be.... lymphoma

Threatening life or tending to cause death... malignant

See MELANOMA.... malignant melanoma

Lymphoid tumour associated with Epstein-Barr (EB) virus. Especially common in malaria endemic areas, such as Africa and Papua New Guinea. May be associated with the immunosuppressive effects of the malaria infection.... burkitt’s lymphoma

Malignant hypertension has nothing to do with cancer; it derives its name from the fact that, if untreated, it runs a rapidly fatal course. (See HYPERTENSION.)... malignant hypertension

A cancer of lymph tissues that is characterized by tumours within the jaw and/or abdomen. It is confined almost exclusively to children living in low-lying, moist, tropical regions of Africa and New Guinea. Anticancer drugs or radiotherapy give complete or partial cure in about 80 per cent of cases. (See also lymphoma.)... burkitt’s lymphoma

See MALIGNANT HYPERTHERMIA.... malignant hyperpyrexia

This disorder is a rare complication of general ANAESTHESIA caused, it is believed, by a combination of an inhalation anaesthetic (usually HALOTHANE) and a muscle-relaxant drug (usually succinycholine). A life-endangering rise in temperature occurs, with muscular rigidity the ?rst sign. TACHYCARDIA, ACIDOSIS and SHOCK usually ensue. About 1:20,000 patients having general anaesthesia suffer from this disorder, which progresses rapidly and is often fatal. Surgery and anaesthesia must be stopped immediately and appropriate corrective measures taken, including the intravenous administration of DANTROLENE. It is a dominantly inherited genetic condition; therefore, when a case is identi?ed it is most important that relatives are screened.... malignant hyperthermia

See LYMPHOMA.... non-hodgkin’s lymphoma

See LYMPHOMA.... t-cell lymphoma

A rapid rise in body temperature to a dangerously high level, brought on by general anaesthesia. The condition is rare. In most cases, susceptibility is inherited; people suffering from certain muscle disorders may also be at risk. The patient’s body temperature rises soon after the anaesthetic is given. Emergency treatment and intensive care are needed.... hyperthermia, malignant

Any cancer of lymphoid tissue (found mainly in the lymph nodes and spleen) other than Hodgkin’s disease. In most cases there is no known cause. Occasionally, the disease is associated with suppression of the immune system, particularly after an organ transplant. One type of nonHodgkin’s lymphoma, known as Burkitt’s lymphoma, is thought to be caused by the Epstein–Barr virus.

There is usually painless swelling of lymph nodes in the neck or groin. The liver and spleen may enlarge, and lymphoid tissue in the abdomen may be affected. Many other organs may become involved, leading to diverse symptoms ranging from headache to skin ulceration. Unless it is controlled, the disease (often marked by fever) progressively impairs the immune system, leading to death from infections or an uncontrolled spread of cancer. Diagnosis is based on a biopsy, usually taken from a lymph node. Chest X-ray, CT scanning, MRI, bone marrow biopsy, and lymphangiography of the abdomen may be needed to assess the extent of the disease.

If the lymphoma is confined to a single group of lymph nodes, treatment consists of radiotherapy. More often, the disease is more extensive, and in such cases anticancer drugs are given. A bone marrow transplant, together with drug treatment and/or radiotherapy, may be performed on some people.... lymphoma, non-hodgkin’s

a group of lymphomas in which abnormal T *lymphocytes are concentrated in the skin. The most common form is *mycosis fungoides.... cutaneous t-cell lymphoma

see Waldenstrom’s macroglobulinaemia.... lymphoplasmacytic lymphoma

see neurocardiogenic syncope.... malignant vasovagal syndrome

a life-threatening syndrome seen after starting *antipsychotic medication. It is characterized by confusion, muscle rigidity, fever, pallor and sweating, urinary incontinence, and a high level of *creatine kinase. Its symptoms can appear similar to *catatonia. Treatment in a high-dependency unit with high-dose benzodiazepines and immediate cessation of antipsychotic drugs is usually indicated.... neuroleptic malignant syndrome

see lymphoma.... non-hodgkin’s lymphoma

The most serious of the 3 types of skin cancer, the other 2 being basal cell carcinoma and squamous cell carcinoma. Malignant melanoma is a tumour of melanocytes, the cells that produce melanin, and is due to long-term exposure to strong sunlight. There are an increasing number of new cases and deaths in the each year from this skin cancer.

Tumours usually develop on exposed skin but may occur anywhere on the body. A melanoma usually grows from an existing mole, which may enlarge, become lumpy, bleed or crust over, change colour, develop an irregular edge, turn into a scab, or become itchy. Occasionally, a melanoma develops in normal skin. The tumour often spreads to other parts of the body. Diagnosis is by a skin biopsy and the melanoma is removed surgically. Radiotherapy or anticancer drugs may also be necessary.... melanoma, malignant