Mania Health Dictionary

Mania: From 5 Different Sources


A mental disorder characterized by episodes of overactivity, elation, or irritability. Mania usually occurs as part of a manic–depressive illness.

Symptoms may include extravagant spending, repeatedly starting new tasks; sleeping less; increased appetite for food, alcohol, sex, and exercise; outbursts of inappropriate anger, laughter, or sudden socializing; and delusions of grandeur. If symptoms are mild, the condition is called hypomania.

Severe mania usually needs treatment in hospital with antipsychotic drugs. Relapses may be prevented by taking lithium or carbamazepine.

Health Source: BMA Medical Dictionary
Author: The British Medical Association
A form of mental disorder characterised by great excitement. (See MENTAL ILLNESS.)
Health Source: Medical Dictionary
Author: Health Dictionary
(Greek) In mythology, the personification of insanity Maniah, Mainia, Maynia, Maniya
Health Source: Medical Dictionary
Author: Health Dictionary
n. a state of mind characterized by excessive cheerfulness and increased activity. The mood is euphoric and can change rapidly to irritability. Thought and speech are pressured and rapid to the point of incoherence and the connections between ideas may be impossible to follow to the point of *loosening of associations. Behaviour is overactive, extravagant, overbearing, and sometimes aggressive. Excessive drug and alcohol use can complicate the picture. Judgment is impaired, with disinhibited behaviour, and therefore the patient may damage his or her own interests. There may be grandiose delusions. *Mixed affective states (such as low mood with pressured speech and irritability) are common. Treatment is usually with medication, such as lithium, *benzodiazepines, or *antipsychotics, and hospital admission is frequently necessary. See also bipolar affective disorder. —manic adj.
Health Source: Oxford | Concise Colour Medical Dictionary
Author: Jonathan Law, Elizabeth Martin
combining form denoting obsession, compulsion, or exaggerated feeling for. Example: pyromania (for starting fires).
Health Source: Oxford | Concise Colour Medical Dictionary
Author: Jonathan Law, Elizabeth Martin

Chlorpromazine

Chlorpromazine is chemically related to the antihistamine drug, PROMETHAZINE HYDROCHLORIDE. One of the ?rst antipsychotic drugs to be marketed, it is used extensively in psychiatry on account of its action in calming psychotic activity without producing undue general depression or clouding of consciousness. The drug is used particularly in SCHIZOPHRENIA and mania. It carries a risk of contact sensitisation, so should be handled with care, and the drug has a wide range of side-effects.... chlorpromazine

Hypomania

Hypomania is a modest manifestation of mania (see under MENTAL ILLNESS). The individual is elated to an extent that he or she may make unwise decisions, and social behaviour may become animated and uninhibited. To the casual observer individuals may, however, seem normal. Treatment is advisable to prevent them from harming their own or their family’s interests. Treatment is as for mania.... hypomania

Psychosis

One of a group of mental disorders in which the affected person loses contact with reality. Thought processes are so disturbed that the person does not always realise that he or she is ill. Symptoms include DELUSIONS, HALLUCINATIONS, loss of emotion, MANIA, DEPRESSION, poverty of thought and seriously abnormal behaviour. Psychoses include SCHIZOPHRENIA, MANIC DEPRESSION and organically based mental disorders. (See also MENTAL ILLNESS.)... psychosis

Thought Disorders

Thought is a mental activity by which people reason, solve problems, form judgements and communicate with each other by speech, writing and behaviour. Disturbances of thought are re?ected in how a person communicates: the normal logic of thought is broken up and a person may randomly move from one subject to another. SCHIZOPHRENIA is a mental illness characterised by thought disorder. Confusion, DEMENTIA, DEPRESSION and MANIA are other conditions in which thought disorders may be a marked feature. (See also MENTAL ILLNESS.)... thought disorders

Euphoria

A state of confident wellbeing. Euphoria is a normal reaction to personal success, but it can also be induced by drugs, including prolonged use of corticosteroid drugs. Euphoria with no rational cause may be a sign of mania, or brain damage due to head injury, dementia, brain tumours, or multiple sclerosis.... euphoria

Lithium

A drug used in the long-term treatment of mania and manic-depressive illness. High levels of lithium in the blood may cause vomiting, diarrhoea, blurred vision, tremor, drowsiness, rash, and, in rare cases, kidney damage.... lithium

Bipolar Disorder

A type of mental illness typi?ed by mood swings between elation (mania) and depression (see MENTAL ILLNESS).... bipolar disorder

Clitoria Ternatea

Linn.

Family: Papilionaceae; Fabaceae.

Habitat: Throughout India in tropical areas; also cultivated in hedges.

English: Butterfly Pea, Winged- leaved Clitoria, Mezereon.

Ayurvedic: Girikarnikaa, Aparaa- jitaa, Aasphota, Girimallikaa, Girikanyaa, Kokilaa,Yonipushpaa, Vishnukraantaa. (Evolvulus alsi- noides Linn. is also known as Vishnukraantaa, Vishnukranti). Used as Shankhapushpi in the South.

Unani: Mezereon Hindi.

Siddha/Tamil: Kakkanam.

Folk: Koyal (Punjab).

Action: Root—cathartic like jalap. Roots cause gripe and tenesmus, hence not recommended as purgative. Used in ascites. Root bark—diuretic (infusion used in irritation of bladder and urethra). Root juice—given in cold milk to liquefy phlegm in chronic bronchitis. The root, bark, seeds and leaves—used for gastric acidity. The root is administered with honey as a general tonic to children for improving mental faculty.

The Ayurvedic Pharmacopoeia of India recommends the dried leaf in migraine, psychoneurosis and mania.

An alcoholic extract of the plant showed sedative and hypothermic effect in rodents.

Rats, fed with ethanol extract of flowers, showed a significantly lowered serum sugar level in experimentally induced diabetes.

The seeds contain a nucleoprotein with its amino acid sequence similar to insulin, but for the absence of his- tidine, threonine, proline and crystine.

Seeds gave cinnamic acid, flavonol gly- coside. Leaves contain glycosides of kaempferol.

In South India, the seeds and roots constitute the drug Shankhapushpi, used as a nervine tonic. In other regions, Canscora decussata, Convolvulus pluricaulis, Evolvulus alsinoides and Lavendula bipinnata are used as Shan- khapushpi.

Dosage: Root—1-3 g powder (API Vol. II); dried leaf—2-5 g; seed—1- 3 g. (API Vol. IV.)... clitoria ternatea

Eclectics

The name commonly applied to the American School Physicians, a distinct group of Medical Doctors who trained in their own schools, and were licensed as M.D.s. They specialized in low-tech, nonhospital rural health care...the famous country doc with a black bag. Besides standard medical procedures, they used a more wholistic approach to disease, sometimes terming themselves Vitalists. They were the most sophisticated of the many movements that arose in response to the almost maniac medical practices of the first half of the 19th century, especially in the United States, where, as always, medicine was philosophically invasive and heroic (often a wonderment to visiting physicians from Paris or London) The Eclectics flourished and grew out of the settlement and usurpment of the Ohio and Missouri Valleys, with a sparse population and no organized hospitals, relied on methods that were not invasive (unless emergencies dictated), used therapies that relied on strengthening natural resistance (no hospitals, just someone’s sod hut) and made particular care to explain and prepare the family or neighbors for THEIR part in caring for the patient...long after the physician left. Scudder, John King, Felter, Ellingwood and Clyce Wilson were some of the more famous Eclectics, and John Uri Lloyd was the most famous pharmacist/pharmacologist within the profession. The Eclectic movement lasted from 1840 to 1937...when the only remaining medical school, unwilling to change to a Flexner Curriculum (as had the other survivors) closed its doors in Cincinnati. Long operating in a tradition of radical, populist and anti­establishment philosophy, they were unable to get any public funding, were unable to ally themselves with full universities (and share faculty and funding), and were unable to expand their teaching facilities with only a base of tuition income. They lost the licensing wars and are no more. Their tradition was exported by practitioners in Germany and Mexico, and the German Eclectics, transformed by that peculiar culture into wild-eyed Nature Curists such as Ehret, Mausert and Lust, started the nucleus for the Naturopathic movement in Yellow Springs, Ohio (next-door to Goddard College) in 1947, helping to found the initial form of the National College of Naturopathic Medicine...10 years after, and 50 miles away from the last Eclectic Medical School. Without benefit of Tanna Leaves or Charleton Heston and an armful of pickled mummy-organs, Eclectecism was reborn into the body of Naturopathy. See: THOMSONIANS... eclectics

Manic Depression

Manic depression, or CYCLOTHYMIA, is a form of MENTAL ILLNESS characterised by alternate attacks of mania and depression.... manic depression

Mental Illness

De?ned simply, this is a disorder of the brain’s processes that makes the sufferer feel or seem ill, and may prevent that person from coping with daily life. Psychiatrists – doctors specialising in diagnosing and treating mental illness – have, however, come up with a range of much more complicated de?nitions over the years.

Psychiatrists like to categorise mental illnesses because mental signs and symptoms do occur together in clusters or syndromes, each tending to respond to certain treatments. The idea that illnesses can be diagnosed simply by recognising their symptom patterns may not seem very scienti?c in these days of high technology. For most common mental illnesses, however, this is the only method of diagnosis; whatever is going wrong in the brain is usually too poorly understood and too subtle to show up in laboratory tests or computed tomography scans of the brain. And symptom-based definitions of mental illnesses are, generally, a lot more meaningful than the vague lay term ‘nervous breakdown’, which is used to cover an attack of anything from AGORAPHOBIA to total inability to function.

There is still a lot to learn about the workings of the brain, but psychiatry has developed plenty of practical knowledge about the probable causes of mental illness, ways of relieving symptoms, and ways of aiding recovery. Most experts now believe that mental illnesses generally arise from di?erent combinations of inherited risk and psychological STRESS, sometimes with additional environmental exposure – for example, viruses, drugs or ALCOHOL.

The range of common mental illnesses includes anxiety states, PHOBIA, DEPRESSION, alcohol and drug problems, the EATING DISORDERS anorexia and bulimia nervosa, MANIC DEPRESSION, SCHIZOPHRENIA, DEMENTIA, and a group of problems related to coping with life that psychiatrists call personality disorders.

Of these mental illnesses, dementia is the best understood. It is an irreversible and fatal form of mental deterioration (starting with forgetfulness and eventually leading to severe failure of all the brain’s functions), caused by rapid death of brain cells and consequent brain shrinkage. Schizophrenia is another serious mental illness which disrupts thought-processes, speech, emotions and perception (how the brain handles signals from the ?ve senses). Manic depression, in which prolonged ‘highs’ of extremely elevated mood and overexcitement alternate with abject misery, has similar effects on the mental processes. In both schizophrenia and manic depression the sufferer loses touch with reality, develops unshakeable but completely unrealistic ideas (delusions), and hallucinates (vividly experiences sensations that are not real, e.g. hears voices when there is nobody there). This triad of symptoms is called psychosis and it is what lay people, through fear and lack of understanding, sometimes call lunacy, madness or insanity.

The other mental illnesses mentioned above are sometimes called neuroses. But the term has become derogatory in ordinary lay language; indeed, many people assume that neuroses are mild disorders that only affect weak people who cannot ‘pull themselves together’, while psychoses are always severe. In reality, psychoses can be brief and reversible and neuroses can cause lifelong disability.

However de?ned and categorised, mental illness is a big public-health problem. In the UK, up to one in ?ve women and around one in seven men have had mental illness. About half a million people in Britain suffer from schizophrenia: it is three times commoner than cancer. And at any one time, up to a tenth of the adult population is ill with depression.

Treatment settings Most people with mental-health problems get the help they need from their own family doctor(s), without ever seeing a psychiatrist. General practictitioners in Britain treat nine out of ten recognised mental-health problems and see around 12 million adults with mental illness each year. Even for the one in ten of these patients referred to psychiatrists, general practitioners usually handle those problems that continue or recur.

Psychiatrists, psychiatric nurses, social workers, psychologists, counsellors and therapists often see patients at local doctors’ surgeries and will do home visits if necessary. Community mental-health centres – like general-practice health centres but catering solely for mental-health problems – o?er another short-cut to psychiatric help. The more traditional, and still more common, route to a psychiatrist for many people, however, is from the general practititioner to a hospital outpatient department.

Specialist psychiatric help In many ways, a visit to a psychiatrist is much like any trip to a hospital doctor – and, indeed, psychiatric clinics are often based in the outpatient departments of general hospitals. First appointments with psychiatrists can last an hour or more because the psychiatrist – and sometimes other members of the team such as nurses, doctors in training, and social workers – need to ask lots of questions and record the whole consultation in a set of con?dential case notes.

Psychiatric assessment usually includes an interview and an examination, and is sometimes backed up by a range of tests. The interview begins with the patient’s history – the personal story that explains how and, to some extent, why help is needed now. Mental-health problems almost invariably develop from a mixture of causes – emotional, social, physical and familial – and it helps psychiatrists to know what the people they see are normally like and what kind of lives they have led. These questions may seem unnecessarily intrusive, but they allow psychiatrists to understand patients’ problems and decide on the best way to help them.

The next stage in assessment is the mental-state examination. This is how psychiatrists examine minds, or at least their current state. Mental-state examination entails asking more questions and using careful observation to assess feelings, thoughts and mental symptoms, as well as the way the mind is working (for example, in terms of memory and concentration). During ?rst consultations psychiatrists usually make diagnoses and explain them. The boundary between a life problem that will clear up spontaneously and a mental illness that needs treatment is sometimes quite blurred; one consultation may be enough to put the problem in perspective and help to solve it.

Further assessment in the clinic may be needed, or some additional tests. Simple blood tests can be done in outpatient clinics but other investigations will mean referral to another department, usually on another day.

Further assessment and tests

PSYCHOLOGICAL TESTS Psychologists work in or alongside the psychiatric team, helping in both assessment and treatment. The range of psychological tests studies memory, intelligence, personality, perception and capability for abstract thinking. PHYSICAL TESTS Blood tests and brain scans may be useful to rule out a physical illness causing psychological symptoms. SOCIAL ASSESSMENT Many patients have social diffculties that can be teased out and helped by a psychiatric social worker. ‘Approved social workers’ have special training in the use of the Mental Health Act, the law that authorises compulsory admissions to psychiatric hospitals and compulsory psychiatric treatments. These social workers also know about all the mental-health services o?ered by local councils and voluntary organisations, and can refer clients to them. The role of some social workers has been widened greatly in recent years by the expansion of community care. OCCUPATIONAL THERAPY ASSESSMENT Mental-health problems causing practical disabilities – for instance, inability to work, cook or look after oneself – can be assessed and helped by occupational therapists.

Treatment The aims of psychiatric treatment are to help sufferers shake o?, or at least cope with, symptoms and to gain or regain an acceptable quality of life. A range of psychological and physical treatments is available.

COUNSELLING This is a widely used ‘talking cure’, particularly in general practice. Counsellors listen to their clients, help them to explore feelings, and help them to ?nd personal and practical solutions to their problems. Counsellors do not probe into clients’ pasts or analyse them. PSYCHOTHERAPY This is the best known ‘talking cure’. The term psychotherapy is a generalisation covering many di?erent concepts. They all started, however, with Sigmund Freud (see FREUDIAN THEORY), the father of modern psychotherapy. Freud was a doctor who discovered that, as well as the conscious thoughts that guide our feelings and actions, there are powerful psychological forces of which we are not usually aware. Applying his theories to his patients’ freely expressed thoughts, Freud was able to cure many illnesses, some of which had been presumed completely physical. This was the beginning of individual analytical psychotherapy, or PSYCHOANALYSIS. Although Freud’s principles underpin all subsequent theories about the psyche, many di?erent schools of thought have emerged and in?uenced psychotherapists (see ADLER; JUNGIAN ANALYSIS; PSYCHOTHERAPY). BEHAVIOUR THERAPY This springs from theories of human behaviour, many of which are based on studies of animals. The therapists, mostly psychologists, help people to look at problematic patterns of behaviour and thought, and to change them. Cognitive therapy is very e?ective, particularly in depression and eating disorders. PHYSICAL TREATMENTS The most widely used physical treatments in psychiatry are drugs. Tranquillising and anxiety-reducing BENZODIAZEPINES like diazepam, well known by its trade name of Valium, were prescribed widely in the 1960s and 70s because they seemed an e?ective and safe substitute for barbiturates. Benzodiazepines are, however, addictive and are now recommended only for short-term relief of anxiety that is severe, disabling, or unacceptably distressing. They are also used for short-term treatment of patients drying out from alcohol.

ANTIDEPRESSANT DRUGS like amitriptyline and ?uoxetine are given to lift depressed mood and to relieve the physical symptoms that sometimes occur in depression, such as insomnia and poor appetite. The side-effects of antidepressants are mostly relatively mild, when recommended doses are not exceeded – although one group, the monoamine oxidase inhibitors, can lead to sudden and dangerous high blood pressure if taken with certain foods.

Manic depression virtually always has to be treated with mood-stabilising drugs. Lithium carbonate is used in acute mania to lower mood and stop psychotic symptoms; it can also be used in severe depression. However lithium’s main use is to prevent relapse in manic depression. Long-term unwanted effects may include kidney and thyroid problems, and short-term problems in the nervous system and kidney may occur if the blood concentration of lithium is too high – therefore it must be monitored by regular blood tests. Carbamazepine, a treatment for EPILEPSY, has also been found to stabilise mood, and also necessitates blood tests.

Antipsychotic drugs, also called neuroleptics, and major tranquillisers are the only e?ective treatments for relieving serious mental illnesses with hallucinations and delusions. They are used mainly in schizophrenia and include the short-acting drugs chlorpromazine and clozapine as well as the long-lasting injections given once every few weeks like ?uphenazine decanoate. In the long term, however, some of the older antipsychotic drugs can cause a brain problem called TARDIVE DYSKINESIA that affects control of movement and is not always reversible. And the antipsychotic drugs’ short-term side-effects such as shaking and sti?ness sometimes have to be counteracted by other drugs called anticholinergic drugs such as procyclidine and benzhexol. Newer antipsychotic drugs such as clozapine do not cause tardive dyskinesia, but clozapine cannot be given as a long-lasting injection and its concentration in the body has to be monitored by regular blood tests to avoid toxicity. OTHER PHYSICAL TREATMENTS The other two physical treatments used in psychiatry are particularly controversial: electroconvulsive therapy (ECT) and psychosurgery. In ECT, which can be life-saving for patients who have severe life-threatening depression, a small electric current is passed through the brain to induce a ?t or seizure. Before the treatment the patient is anaesthetised and given a muscle-relaxing injection that reduces the magnitude of the ?t to a slight twitching or shaking. Scientists do not really understand how ECT works, but it does, for carefully selected patients. Psychosurgery – operating on the brain to alleviate psychiatric illness or di?cult personality traits – is extremely uncommon these days. Stereo-tactic surgery, in which small cuts are made in speci?c brain ?bres under X-ray guidance, has super-seded the more generalised lobotomies of old. The Mental Health Act 1983 ensures that psychosurgery is performed only when the patient has given fully informed consent and a second medical opinion has agreed that it is necessary. For all other psychiatric treatments (except another rare treatment, hormone implantation for reducing the sex drive of sex o?enders), either consent or a second opinion is needed – not both. TREATMENT IN HOSPITAL Psychiatric wards do not look like medical or surgical wards and sta? may not wear uniforms. Patients do not need to be in their beds during the day, so the beds are in separate dormitories. The main part of most wards is a living space with a day room, an activity and television room, quiet rooms, a dining room, and a kitchen. Ward life usually has a certain routine. The day often starts with a community meeting at which patients and nurses discuss issues that affect the whole ward. Patients may go to the occupational therapy department during the day, but there may also be some therapy groups on the ward, such as relaxation training. Patients’ symptoms and problems are assessed continuously during a stay in hospital. When patients seem well enough they are allowed home for trial periods; then discharge can be arranged. Patients are usually followed up in the outpatient clinic at least once.

TREATING PATIENTS WITH ACUTE PSYCHIATRIC ILLNESS Psychiatric emergencies – patients with acute psychiatric illness – may develop from psychological, physical, or practical crises. Any of these crises may need quick professional intervention. Relatives and friends often have to get this urgent help because the sufferer is not ?t enough to do it or, if psychotic, does not recognise the need. First, they should ring the person’s general practitioner. If the general practitioner is not available and help is needed very urgently, relatives or friends should phone the local social-services department and ask for the duty social worker (on 24-hour call). In a dire emergency, the police will know what to do.

Any disturbed adult who threatens his or her own or others’ health and safety and refuses psychiatric help may be moved and detained by law. The Mental Health Act of 1983 authorises emergency assessment and treatment of any person with apparent psychiatric problems that ful?l these criteria.

Although admission to hospital may be the best solution, there are other ways that psychiatric services can respond to emergencies. In some districts there are ‘crisis intervention’ teams of psychiatrists, nurses, and social workers who can visit patients urgently at home (at a GP’s request) and, sometimes, avert unnecessary admission. And research has shown that home treatment for a range of acute psychiatric problems can be e?ective.

LONG-TERM TREATMENT AND COMMUNITY CARE Long-term treatment is often provided by GPs with support and guidance from psychiatric teams. That is ?ne for people whose problems allow them to look after themselves, and for those with plenty of support from family and friends. But some people need much more intensive long-term treatment and many need help with running their daily lives.

Since the 1950s, successive governments have closed the old psychiatric hospitals and have tried to provide as much care as possible outside hospital – in ‘the community’. Community care is e?ective as long as everyone who needs inpatient care, or residential care, can have it. But demand exceeds supply. Research has shown that some homeless people have long-term mental illnesses and have somehow lost touch with psychiatric services. Many more have developed more general long-term health problems, particularly related to alcohol, without ever getting help.

The NHS and Community Care Act 1990, in force since 1993, established a new breed of professionals called care managers to assess people whose long-term illnesses and disabilities make them unable to cope completely independently with life. Care managers are given budgets by local councils to assess people’s needs and to arrange for them tailor-made packages of care, including services like home helps and day centres. But co-ordination between health and social services has sometimes failed – and resources are limited – and the government decided in 1997 to tighten up arrangements and pool community-care budgets.

Since 1992 psychiatrists have had to ensure that people with severe mental illnesses have full programmes of care set up before discharge from hospital, to be overseen by named key workers. And since 1996 psychiatrists have used a new power called Supervised Discharge to ensure that the most vulnerable patients cannot lose touch with mental-health services. There is not, however, any law that allows compulsory treatment in the community.

There is ample evidence that community care can work and that it need not cost more than hospital care. Critics argue, however, that even one tragedy resulting from inadequate care, perhaps a suicide or even a homicide, should reverse the march to community care. And, according to the National Schizophrenia Fellowship, many of the 10–15 homicides a year carried out by people with severe mental illnesses result from inadequate community care.

Further information can be obtained from the Mental Health Act Commission, and from MIND, the National Association for Mental Health. MIND also acts as a campaigning and advice organisation on all aspects of mental health.... mental illness

Lithium Carbonate

A drug widely used in the PROPHYLAXIS treatment of certain forms of MENTAL ILLNESS. The drug should be given only on specialist advice. The major indication for its use is acute MANIA; it induces improvement or remission in over 70 per cent of such patients. In addition, it is e?ective in the treatment of manic-depressive patients (see MANIC DEPRESSION), preventing both the manic and the depressive episodes. There is also evidence that it lessens aggression in prisoners who behave antisocially and in patients with learning diffculties who mutilate themselves and have temper tantrums.

Because of its possible toxic effects – including kidney damage – lithium must only be administered under medical supervision and with monitoring of the blood levels, as the gap between therapeutic and toxic concentrations is narrow. Due to the risk of its damaging the unborn child, it should not be prescribed, unless absolutely necessary, during pregnancy – particularly not in the ?rst three months. Mothers should not take it while breast feeding, as it is excreted in the milk in high concentrations. The drug should not be taken with DIURETICS.... lithium carbonate

Neuroleptics

Drugs used to quieten disturbed patients, whether this is the result of brain damage, MANIA, DELIRIUM, agitated DEPRESSION or an acute behavioural disturbance. They relieve the ?orid PSYCHOTIC symptoms such as hallucinations and thought-disorder in SCHIZOPHRENIA and prevent relapse of this disorder when it is in remission.

Most of these drugs act by blocking DOPAMINE receptors. As a result they can give rise to the extrapyramidal effects of PARKINSONISM and may also cause HYPERPROLACTINAEMIA.

Troublesome side-effects may require control by ANTICHOLINERGIC drugs. The main antipsychotic drugs are: (i) chlorpromazine, methotrimeprazine and promazine, characterised by pronounced sedative effects and a moderate anticholinergic and extrapyramidal e?ect; (ii) pericyazine, pipothiazine and thioridazine, which have moderate sedative effects and marked anticholinergic effects, but less extrapyramidal effects than the other groups; (iii) ?uphenazine, perphenazine, prochlorperazine, sulpiride and tri?uoperazine, which have fewer sedative effects and fewer anticholinergic effects, but more pronounced extrapyramidal effects.... neuroleptics

Arthritis, Lupus

A form of arthritis associated with systemic lupus erythematosis in young girls. An auto-immune disease which may involve the heart, kidney, CNS or other systems.

Symptoms: Joint pains with feverishness, loss of weight, anaemia and red raised patches of skin on nose and face (butterfly rash). Swelling of the joints resembles rheumatoid arthritis. Chest and kidney disease possible. Personality changes with depression followed by mania and possible convulsions.

Treatment. Standard orthodox treatments: aspirin, steroids. Alternatives: Echinacea (rash), Valerian (mental confusion), Lobelia (chest pains), Parsley Piert (kidney function).

Tablets/capsules. Echinacea. Poke root. Dandelion. Valerian. Wild Yam. Prickly Ash bark.

Powders. Echinacea 2; Dandelion 1; Wild Yam half; Poke root quarter; Devil’s Claw half; Fennel half. Mix. Dose: 500mg (two 00 capsules or one-third teaspoon) thrice daily. In water or cup of Fenugreek tea. Tinctures. Dandelion 4; Valerian 1; Prickly Ash half; Poke root half; Peppermint quarter. Mix. Dose: 1 teaspoon thrice daily, in water or cup Fenugreek tea.

Tincture. Queen’s Delight BHP (1983) 1:5 in 45 per cent alcohol. Dose 1-4ml (15-60 drops).

Topical. Plantain Salvo. Castor oil. Oil Cajeput or Sassafras. Comfrey or Chickweed cream.

Diet. Young girls may require diet for anaemia.

Supplementation. Daily. Vitamins A, B6, B12, C, D. Dolomite (1500mg). Calcium Pantothenate (500mg). Iron: Men (10mg), women (18mg). ... arthritis, lupus

Delirium Tremens

D.T.s Occurs when heavy drinkers are deprived of alcohol, or from mental shock. Hallucinations, during which he talks to himself. Imagines he is chased by horrible creatures: reptiles, birds, insects. Violent tremors, sleeplessness, irritability and fever require careful nursing in a darkened room. A small amount of alcohol may be necessary to ensure sleep. Overdoses of coffee can have a similar effect.

Alternatives. Teas. Hops, Passion flower. Motherwort (with heart symptoms). Oats.

Tablets/capsules. Motherwort, Passion flower. Mistletoe.

Powders. Formula. Passion flower 2; Hops (lupulin) 1; Jamaica Dogwood 1. Dose: 750mg (three 00 capsules or half a teaspoon) every 2 hours.

Tinctures. Formula. Equal parts: Passion flower; Hops; Oats. Dose: one to three 5ml teaspoons in water, every 2 hours.

Practitioner. Tincture Stramonium, Dr Fyfe, Eclectic Medical Review, advises: “With mania present in acute inflammation. Furious, noisy, raving: one drop Tincture Stramonium every two hours.”

Tincture Cinchona (Peruvian bark) BPC (1949). 2-4ml 2-3 times daily. 2-3 drops Tincture Capsicum enhances its action.

German traditional. Arnica. Suggest: Tincture Arnica, 2-5 drops in water 2-3 times daily. ... delirium tremens

Affective Disorders

Mental illnesses characterized predominantly by marked changes in affect. Mood may vary over a period of time between mania (extreme elation) and severe depression. (See also manic–depressive illness.)... affective disorders

Carbamazepine

An anticonvulsant drug, chemically related to the tricyclic antidepressants.

Carbamazepine is mainly used in the long-term treatment of epilepsy.

It is also used to treat neuralgia and psychological disorders, such as mania.... carbamazepine

Rabies

An acute and potentially fatal disease, caused by a rhabdovirus called Lyssavirus, which affects the nervous system of animals, particularly carnivora, and may be communicated from them to humans. Infection from person to person is very rare, but those in attendance on a case should take precautions to avoid being bitten or allowing themselves to be contaminated by the patient’s saliva, as this contains the causative virus.

The disease is ENDEMIC in dogs and wolves in some countries; an EPIDEMIC may occasionally occur. It also occurs in foxes, coyotes and skunks, as well as in vampire bats. Thanks to QUARANTINE measures, since 1897 rabies has been rare in Great Britain, which still retains strict measures (the Rabies Act) to prevent the entry of infected animals into the country, including a six-month quarantine period and vaccination (see IMMUNISATION). This policy was relaxed somewhat in 2001 with the launch of the Pet Travel Scheme; this allows cats and dogs to enter the UK from speci?ed countries without the need for quarantine, as long as stringent conditions as to microchipping and vaccinations are met. Full details can be obtained from the Department for the Environment, Food and Rural A?airs (DEFRA) or from a veterinary surgeon engaged in operating the scheme. Six months has to elapse between vaccination against rabies and a positive blood test before the ‘pet passport’ can be issued.

Rabies is highly infectious from the bite of an animal already affected, but the chance of infection from di?erent animals varies. Thus only about one person in every four bitten by rabid dogs contracts rabies, whilst the bites of rabid wolves and cats almost invariably produce the disease.

Symptoms In animals there are two types of the disease: mad rabies and dumb rabies. In the former, the dog (or other animal) runs about, snapping at objects and other animals, unable to rest; in the latter, which is also the ?nal stage of the mad type, the limbs become paralysed and the dog crawls about or lies still.

In humans the incubation period is usually 6–8 weeks, but may be as short as ten days or as long as two years. The disease begins with mental symptoms, the person becoming irritable, restless and depressed. Fever and DYSPHAGIA follow. The irritability passes into a form of MANIA and the victim has great di?culty in swallowing either food or drink.

Treatment The best treatment is, of course, preventive. Local treatment consists of immediate, thorough and careful cleansing of the wound-surfaces and surrounding skin. This is followed by a course of rabies vaccine therapy.

Only people bitten (or in certain circumstances, licked) by a rabid animal or by one thought to be infected with rabies need treatment; this is with rabies vaccine and antiserum and one of the IMMUNOGLOBULINS. A person previously vaccinated against rabies who is subsequently bitten by a rabid animal should be given three or four doses of the vaccine. The vaccine is also used to give protection to those liable to infection, such as kennel-workers and veterinary surgeons. Those who develop the disease require intensive care with ventilatory support, despite which the death rate is very high.... rabies

Aggression

A general term for a wide variety of acts of hostility. A number of factors, including human evolutionary survival strategies, are thought to be involved in aggression. Androgen hormones, the male sex hormones, seem to promote aggression, whereas oestrogen hormones, the female sex hormones, actively suppress it. Age is another factor; aggression is more common among teenagers and young adults. Sometimes, a brain tumour or head injury leads to aggressive behaviour.

Psychiatric conditions associated with aggressive outbursts are schizophrenia, antisocial personality disorder, mania, and abuse of amfetamines or alcohol.

Temporal lobe epilepsy, hypoglycaemia, and confusion due to physical illnesses are other, less common, medical causes.... aggression

Antipsychotic Drugs

A group of drugs used to treat psychoses (mental disorders involving loss of contact with reality), particularly schizophrenia and mania in bipolar disorder (see manic– depressive illness). Antipsychotic drugs may also be used to sedate people who have other mental disorders (such as dementia) and who are very agitated or aggressive. Antipsychotics include phenothiazine drugs, butyrophenones, such as haloperidol, and several new drugs including risperidone, which is used to treat the symptoms of mania.

Antipsychotics can cause drowsiness, lethargy, dyskinesia, and parkinsonism.

Other possible side effects include dry mouth, blurred vision, and difficulty in passing urine. However, newer drugs may have fewer side effects when used in the long term.... antipsychotic drugs

Haloperidol

An antipsychotic drug used to treat mental illnesses such as schizophrenia and mania.

Haloperidol is also given to control symptoms of Gilles de la Tourette’s syndrome and, in small doses, to sedate people who are aggressive as a result of dementia.

Side effects include drowsiness, lethargy, weight gain, dizziness, and parkinsonism.... haloperidol

Megalomania

An exaggerated sense of one’s own importance or ability that often occurs in mania. Megalomania may take the form of a delusion of grandeur, or of a desire to organize activities that are expensive, large in scale, and involve many people.... megalomania

Mood Disorders

Disorders in which the emotions are affected: mania, depression, and manic–depressive illness.... mood disorders

Prochlorperazine

A phenothiazine-type antipsychotic drug used to relieve symptoms of certain psychiatric disorders, such as schizophrenia and mania.

It is also used in small doses as an antiemetic drug.

It may cause involuntary movements of the face and limbs, lethargy, dry mouth, blurred vision, and dizziness.... prochlorperazine

Acro

combining form denoting 1. extremity; tip. Example: acrohypothermy (abnormal coldness of the extremities (hands and feet). 2. height; promontory. Example: acrophobia (morbid dread of heights). 3. extreme; intense. Example: acromania (an extreme degree of mania).... acro

Manic–depressive Illness

A mental disorder that is characterized by a disturbance of mood. The disturbance may be unipolar (consisting of either depression or mania) or bipolar (swinging between the two). In a severe form that is sometimes referred to as manic– depressive psychosis, there may also be grandiose ideas or negative delusions.

Abnormalities in brain biochemistry, or in the structure and/or function of certain nerve pathways within the brain, could underlie manic–depressive illness. An inherited tendency is also an established causative factor.Severe manic–depressive illness often needs hospital treatment. Antidepressant drugs and/or ECT are used to treat depression, and antipsychotic drugs are given to control manic symptoms. Carbamazepine or lithium may be used to prevent relapse.

Group therapy, family therapy, and individual psychotherapy may be useful in treatment. Cognitive–behavioural therapy may also be helpful. With treatment, more than 80 per cent of patients improve or remain stable. Even those with severe illness may be restored to near normal health with lithium.... manic–depressive illness

Affective Disorder

(mood disorder) any psychiatric disorder featuring abnormalities of mood or emotion (*affect). The most serious of these are *depression and *mania. Other affective disorders include *SAD (seasonal affective disorder).... affective disorder

Antipsychotic

n. any one of a group of drugs used to treat severe mental disorders (psychoses), including schizophrenia and mania; some are administered in small doses to relieve anxiety and tic disorders or to treat impulsivity in *emotionally unstable personality disorder. Formerly called major tranquillizers, and later typical and atypical antipsychotics, they are now known as first- and second-generation antipsychotics. The first-generation (or typical) antipsychotics include the *phenothiazines (e.g. *chlorpromazine), *butyrophenones (e.g. *haloperidol), and thioxanthenes (e.g. *flupentixol). Side-effects of antipsychotic drugs can include *extrapyramidal effects, sedation, *antimuscarinic effects, weight gain, and *long QT syndrome. The second-generation (or atypical) antipsychotics are a group of more recently developed drugs that are in theory associated with fewer extrapyramidal effects than first-generation antipsychotics: they include *clozapine, *risperidone, amisulpride, aripiprazole, olanzapine, and quetiapine. Antipsychotics act on various neurotransmitter receptors in the brain, including dopamine, histamine, serotonin, and cholinergic receptors. Most of them block neurotransmitter activity, but some have partially agonistic effects. Recent evidence suggests that there are significant differences among the second-generation antipsychotics regarding their efficacy and side-effect profiles. Clozapine, amisulpride, and olanzapine were found to be the most effective antipsychotics. Clozapine, zotepine, and olanzapine caused the most weight gain; haloperidol, zotepine, and chlorpromazine caused the most extrapyramidal side-effects; sertindole, amisulpride, and ziprasidone caused the most QT-prolongation; and clozapine, zotepine, and chlorpromazine caused the most sedation.... antipsychotic

Bipolar Affective Disorder

(BPAD) a severe mental illness affecting about 1% of the population and causing repeated episodes of *depression, *mania, and/or *mixed affective state. Type I BPAD consists equally of depressive and manic episodes, whereas Type II BPAD consists primarily of depressive episodes with occasional phases of *hypomania. Treatment is that of the individual episode. Antidepressants and antipsychotics are used to treat depressive episodes together with mood stabilizers (e.g. *lithium) or antiepileptics. Mood stabilizers are also used to prevent or lessen future episodes. Mania is most commonly treated with benzodiazepines, antipsychotics, and mood stabilizers. ECT may be used for either episode in severe cases. To prevent future episodes many patients need combinations of mood stabilizers with *antidepressant or *antipsychotic medication. Certain types of educational *psychotherapy can be used to prevent relapse as well as to treat the individual episode. Up to 50% of BPAD patients have substance abuse problems, and many suffer from residual mood symptoms between episodes.

BI-RADS (Breast Imaging Reporting and Data System) a standardized system of terminology, report organization, assessment, and classification for mammography and ultrasound or MRI of the breast. BI-RADS reporting enables radiologists to communicate results to the referring physician clearly and consistently, with a final assessment and specific management recommendations.

The success of BI-RADS has inspired several other systems of the same kind: TI-RADS (Thyroid Imaging Reporting and Data System); LI-RADS (Liver Imaging Reporting and Data System); and PI-RADS (Prostate Imaging Reporting and Data System).... bipolar affective disorder

Delusional Perception

a *Schneiderian first-rank symptom in which a person believes that a normal percept (product of perception) has a special meaning for him or her. For example, a cloud in the sky may be misinterpreted as meaning that someone has sent that person a message to save the world. While the symptom is particularly indicative of *schizophrenia, it also occurs in other psychoses, including *mania (in which it often has grandiose undertones).... delusional perception

Ecstasy

n. a sense of extreme wellbeing and bliss. The word applies particularly to *trance states dominated by religious thinking. While not necessarily pathological, it can be caused by epilepsy (especially of the temporal lobe) or by *schizophrenia or *mania.... ecstasy

Elation

n. a state of cheerful excitement and enthusiasm. Marked elation of mood is a characteristic of *mania or *hypomania.... elation

Flight Of Ideas

accelerated thinking that occurs in psychosis, mania, hypomania, and attention-deficit/hyperactivity disorder. Speech is rapid, moving from one topic to another and reflecting casual associations between ideas. In contrast to *loosening of associations, the link between themes is preserved, albeit often difficult to follow.... flight of ideas

Delusion

n. a belief that is held with unshakable conviction, cannot be altered by rational argument, and is outside the person’s normal cultural or subcultural belief system. The belief is usually wrong, but can occasionally be true: the abnormal pathology lies in the irrational way in which the person comes to the belief. In mental illness it may be a false belief that the individual is persecuted by others (paranoid delusion; see paranoia), is very powerful (grandiose delusion), is guilty of something they have not actually done, is poor, or is a victim of physical disease. Delusions may be a symptom of *schizophrenia, acute intoxication, *mania, *delirium, or an organic *psychosis. The intensity of the delusional belief may vary over time.... delusion

Depression

n. 1. a mental state characterized by excessive sadness. 2. a mood disorder characterized by the pervasive and persistent presence of core and somatic symptoms on most days for at least two weeks. Core symptoms include low mood and loss or impairment of motivation, energy, interest, and enjoyment. Somatic symptoms include impaired memory and concentration, loss of appetite and libido, insomnia, early morning wakening (more than two hours earlier than normal), physical and mental activity that is either agitated and restless or slow and retarded, and a diurnal variation of mood (usually patients feel particularly depressed in the mornings). Additional symptoms include automatic negative thoughts, pessimistic views of oneself, the future, and the present (Beck’s triad of depression), suicidal *ideation, tearfulness, *alexithymia, and a poor frustration tolerance. A single period of experiencing these symptoms is called a major depressive episode; experiencing one or more of such episodes (without mania) is known as major depression, major depressive disorder, or clinical depression. Depression may or may not be triggered by stressful events or trauma. Risk factors include genetic and social elements (e.g. poverty, lack of confidants, substance abuse) and psychological elements (e.g. the presence of personality disorder, a history of abuse or *dysthymia). Treatment is with *antidepressant drugs, *cognitive behavioural therapy, and/or *psychotherapy. Severe cases may need *electroconvulsive therapy. The course of the illness can be a single episode or recurrent episodes, or it may become chronic. —depressive adj.... depression

Electroconvulsive Therapy

(ECT) a treatment for severe depression and occasionally for *puerperal psychosis, catatonia, and *mania. A convulsion is produced by passing an electric current through the brain; this is thought to induce stimulation, and is modified by giving a *muscle relaxant drug and an *anaesthetic, so that in fact only a few muscle twitches are produced. The procedure can temporarily cause confusion and headache, which almost always pass off within a few hours. Patients often complain of memory problems during treatment, which normally subside when the treatment has ended. These side-effects are reduced by unilateral treatment, in which the current is passed only through the non-dominant hemisphere of the brain. A course of ECT usually entails between 6 and 10 treatments; sometimes up to 16 treatments are given to achieve remission of depression. ECT is effective in about 50% of patients in whom no other antidepressant treatment was successful, and NICE guidelines suggest it should be used in such cases. However, the beneficial effect on mood does not always last. Occasionally maintenance ECT (usually involving one treatment every 2–4 weeks) is given to avoid relapse after a completed course of ECT. Under the Mental Health Act 1983 (as amended 2007), special legal provision applies to ECT.... electroconvulsive therapy

Hyperpraxia

n. excessive motor activity, such as is seen in *mania and *attention-deficit/hyperactivity disorder.... hyperpraxia

Insomnia

n. inability to fall asleep or to remain asleep for an adequate length of time. Insomnia may be associated with physical disease, particularly if there are painful symptoms, or psychiatric illnesses, such as depression, anxiety, or mania.... insomnia

Logorrhoea

n. a rapid flow of voluble speech, often with incoherence, such as is encountered in *mania.... logorrhoea

Loosening Of Associations

(in psychiatry) a form of *formal thought disorder in which the linkage of the person’s train of thoughts gets lost or disrupted. This may be a sign of severe psychotic illness or mania.... loosening of associations

Mixed Affective State

a state of disordered mood that combines elements of *mania and *depression; it is a common feature of *bipolar affective disorder. Symptoms include overactivity, flight of ideas, depressed mood, and suicidal *ideation.... mixed affective state

Perphenazine

n. a phenothiazine *antipsychotic drug used to treat schizophrenia, mania, anxiety, and severe agitation and to prevent and treat severe nausea and vomiting. Side-effects are similar to those of *fluphenazine.... perphenazine

Risperidone

n. a second-generation *antipsychotic drug used in the treatment of schizophrenia, mania, and other psychoses. Side-effects include nausea, *akathisia, headache, and sedation.... risperidone

Tranquillizer

n. a drug that produces a calming effect, relieving anxiety and tension. *Antipsychotic drugs (formerly known as major tranquillizers) have this effect and are used to treat severe mental disorders (psychoses), including schizophrenia and mania. *Anxiolytic drugs (formerly known as minor tranquillizers) are used to relieve anxiety and tension due to various causes.... tranquillizer

Schneiderian First- And Second-rank Symptoms

symptoms of *schizophrenia first classified by German psychiatrist Kurt Schneider (1887–1967) in 1938. First-rank symptoms were considered by Schneider to be particularly indicative of schizophrenia; they include all forms of *thought alienation, *delusional perception, *passivity, and third-person auditory *hallucinations in the form of either a running commentary or voices talking about the patient among themselves. Some schizophrenic patients never exhibit first-rank symptoms or only experience them in some psychotic episodes. They may also occur in *mania. Second-rank symptoms are common symptoms of schizophrenia but also often occur in other forms of mental illness. They include *delusions of reference, paranoid and persecutory *delusions, and second-person auditory hallucinations.... schneiderian first- and second-rank symptoms



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