Apple (Malus pumila).Plant Part Used: Leaf, root, flower, fruit, bulb, bark, whole plant.Dominican Medicinal Uses: Fruit: raw, ingested, for treatment or prevention of high blood pressure, high cholesterol, heart disease and nutrition; tea, orally, for common cold, flu-like symptoms, menopausal hot flashes and relaxation.Safety: Fruit is widely consumed and generally considered safe.Clinical Data: Human clinical trials: alleviation of gastro-intestinal enteritis (fruit).Laboratory & Preclinical Data: In vivo: anti-inflammatory, antirheumatic (ethanol extract).In vitro: antioxidant (phenols).* See entry for Manzana in “Part 3: Dominican Medicinal Plant Profiles” of this book for more information, including references.