Medulloblastoma Health Dictionary

Medulloblastoma: From 2 Different Sources


A type of cancerous brain tumour that occurs mainly in children.

The tumour usually arises from the cerebellum, which is concerned with posture, balance, and coordination.

It grows rapidly and may spread to other parts of the brain and to the spinal cord.

A morning headache, repeated vomiting, and a clumsy gait develop.

There are also frequent falls.

The tumour is diagnosed by CT scanning or MRI and often responds to radiotherapy.

Surgery and anticancer drugs may also be needed.

Health Source: BMA Medical Dictionary
Author: The British Medical Association
n. a malignant brain tumour (see cerebral tumour) that occurs during childhood. It is derived from cells that have the apparent potential to mature into neurons and develops in the cerebellum, the part of the brain that is predominantly involved in the control of balance. The flow of cerebrospinal fluid (CSF) may become obstructed, causing *hydrocephalus. Symptoms include headaches, dizziness, and unsteadiness. Treatment involves surgery to remove most of the tumour and restore CSF flow, followed by radiotherapy directed using *stereotactic localization. Medulloblastoma is the second most common form of cancer of childhood (after leukaemia); recent advances have improved the survival rate so that 40% of affected children live for more than five years.
Health Source: Oxford | Concise Colour Medical Dictionary
Author: Jonathan Law, Elizabeth Martin

Brain Tumour

An abnormal growth in or on the brain. Tumours may be primary growths arising directly from tissues within the skull or metastases (secondary growths) that have spread from tumours elsewhere in the body. The cause of primary brain tumours is not known. About 60 per cent are gliomas (frequently cancerous), which arise from the brain tissue. Other primary tumours include meningiomas, acoustic neuromas, and pituitary tumours. Most of these tumours are noncancerous, but their size can cause local damage. Certain types of primary brain tumour mainly affect children. These include 2 types of glioma called medulloblastoma and cerebellar astrocytoma. Primary brain tumours virtually never spread (metastasize) outside the central nervous system.

Symptoms include muscle weakness, loss of vision, or other sensory disturbances, speech difficulties, and epileptic seizures. Increased pressure within the skull can cause headache, visual disturbances, vomiting, and impaired mental functioning. Hydrocephalus may occur.

When possible, primary tumours are removed by surgery after opening the skull (see craniotomy).

In cases where a tumour cannot be completely removed, as much as possible of it will be cut away to relieve pressure.

For primary and secondary tumours, radiotherapy or anticancer drugs may also be given.

Corticosteroid drugs are often prescribed temporarily to reduce the size of a tumour and associated brain swelling.... brain tumour

Glioma

A type of brain tumour arising from the supporting connective tissue, (glial cells), in the brain. Types of glioma include astrocytoma, glioblastoma multiforme, ependymoma, medulloblastoma, and oligodendroglioma. Symptoms, diagnosis, and treatment are as for other types of brain tumour.... glioma

Cerebral Tumour

an abnormal multiplication of brain cells. Any tumorous swelling tends to compress or even destroy the healthy brain cells surrounding it and – because of the rigid closed nature of the skull – increases the pressure on the brain tissue. Malignant brain tumours, which are much more common in children than in adults, include *medulloblastomas and *gliomas; these grow rapidly, spreading through the otherwise normal brain tissue and causing progressive neurological disability. Benign tumours, such as *meningiomas, grow slowly and compress the brain tissue. Both benign and malignant tumours commonly cause fits. Benign tumours are often cured by total surgical resection. Malignant tumours may be treated by neurosurgery, chemotherapy, and radiotherapy, but the outcome for most patients remains poor.... cerebral tumour



Recent Searches