Megakaryocyte Health Dictionary

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Megakaryocyte: From 1 Different Sources

n. a cell in the bone marrow that produces *platelets. It is large (35–160 ?m in diameter), with an irregular multilobed nucleus, and with *Romanowsky stains its abundant cytoplasm appears pale blue with fine reddish granules. See also thrombopoiesis.
Health Source: Oxford | Concise Colour Medical Dictionary
Author: Jonathan Law, Elizabeth Martin

Giant Cell

any large cell, such as a *megakaryocyte. Giant cells may have one or many nuclei.... giant cell

Megakaryoblast

n. a cell that gives rise to the platelet-forming cell *megakaryocyte, found in the blood-forming tissue of the bone marrow. It is derived from a *haemopoietic stem cell and matures via an intermediate stage (promegakaryocyte) into a megakaryocyte.... megakaryoblast

Promegakaryocyte

n. an immature cell, found in the bone marrow, that develops into a *megakaryocyte.... promegakaryocyte

Thrombocythaemia

n. a disease in which there is an abnormal proliferation of the cells that produce blood *platelets (*megakaryocytes), leading to an increased number of platelets in the blood. This may result in an increased tendency to form clots within blood vessels (thrombosis); alternatively the function of the platelets may be abnormal, leading to an increased tendency to bleed. Treatment is by radiotherapy, *cytotoxic drugs, *interferon, or drugs that inhibit *megakaryocyte maturation.... thrombocythaemia

Thrombopoiesis

n. the process of blood *platelet production. Platelets are formed as fragments of cytoplasm shed from giant cells (*megakaryocytes) in the bone marrow by a budding process.... thrombopoiesis

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