Melissa axillaris Health Dictionary

(Benth.) Bakh f.

Synonym: M. parviflora Benth.

Family: Lamiaceae.

Habitat: Temperate and alpine Himalaya, from Garhwal to Bhutan and in Darjeeling and Aka, Mishmi and Khasi hills at l,000-3,600 m.

Unani: Billilotan.

Action: Carminative, diaphoretic, febrifuge in cases of catarrh and 406 Melissa officinalis Linn. influenza. The fruit is considered a brain tonic and useful in hypochondriac conditions.

The aerial parts of the plant yield 2% essential oil which is a good source of monoterpenic alcohols and aldehydes. It contains d-camphene 2.5, dl-alpha- pinene 2.3, 1-beta-pinene 2.13, delta- carene 2.05, d-limonene 12.95, azulene 1.26, linalool 13.36,1,8-cineole 9.33, cit- ronellal 4.0, citronellol 8.2, citral 13.0, geraniol 21.01, neptalactone 1.91, thymol 4.0 and citronellic acid 2.0%.

The herb is used as a substitute for Melissa officinalis Linn.

MJ

Habitat: Indigenous to the east Mediterranean region; introduced in India.

English: Mountain Balm, Sweet or Lemon Balm.

Unani: Baadranjboyaa, Billilotan. (Nepeta cataria Linn. and Nepeta hindostana Haines are also known as Billilotan.)

Action: Antidepressant, antispasmodic, antihistaminic, antiviral. Used in anxiety neurosis and nervous excitability, palpitation and headache. Also in hyperthyroidism.

Key application: In nervous sleeping disorders and functional gastrointestinal complaints. (German Commission E, ESCOP.) Externally for Herpes labialis (cold sores). (ESCOP.) As sedative and topi- cal antiviral. (The British Herbal Pharmacopoeia.)

Only fresh (herb within 6 months after collection) is usable as a sedative, because of low volatile oil content and its high volatility.

The volatile oil of the herb (0.100.2%) consists mainly of geranial and neral, with caryophyllene oxide and smaller quantities of terpenes; glycosides of the alcoholic or phenolic components of the volatile oil (including eugenol glucoside); caf- feic acid derivatives (rosmaric acid); flavonoids (including cymaroside, cos- mosiin, rhamnocitrin, isoquercitrin); triterpene acids (including ursolic acid).

Hot water extracts exhibit antiviral properties, mainly due to rosmaric acid and other polyphenols. (A cream containing the extracts of Balm is used for the treatment of cutaneous lesions of Herpes simplex virus.) Aqueous extracts inhibit tumour cell dividing.

Freeze-dried aqueous extracts inhibit many of the effects of exogenous and endogenous thyroid stimulating hormones (TSH) on bovine thyroid gland by interfering with the binding of TSH to plasma membranes and by inhibiting the enzyme iodothyronine deiodinase in vitro.

The anti-hormonal, mainly anti- thyroid effects of Balm are well documented. (Potter's New Cyclopedia, Sharon.M. Herr.)

For mild to moderate Alzheimer disease, 60 drops per day of standardized Lemon Balm extract (1 : 11 45% alcohol) was prescribed daily. Results were encouraging. (J Neurol Neurosurg Memecylon edule Roxb. 407 Psychiatry, 74, 2003; Natural Medicines Comprehensive Database, 2007.) (For cholinergic activity, BMJ, 325, 2002, 1312-1233.)