Linn.Family: Gentianaceae.
Habitat: Native to Britain and Europe; found in Kashmir.
English: Bogbean, Buckbean, Goat's bean, Marsh Trefoil.Folk: Buckbean.Action: Bitter tonic, deobstruent. Laxative in large doses. Used for diseases of liver and gallbladder, and rheumatism. (Contraindicated in diarrhoea, dysentery and colitis.)
Key application: Leaf—in loss of appetite, peptic discomforts. (German Commission E.) As a bitter tonic. (The British Herbal Pharmacopoeia.) The drug stimulates saliva and gastric juice secretion. (German Commission E.)The herb contains iridoid glyco- sides, foliamenthin, dihydrofoliamen- thin, menthiafolin and loganin; pyri- dine alkaloids including gentianine; coumarins (scopoletin); phenolic acids (caffeic, with protocatechuic, ferulic, sinapic, vanillic including others; fla- vonoids including rutin, hyperoside.Choleretic action of the herb is attributed to the synergistic action of caffeic and ferulic acids and iridoid glycosides.Scoparone and scopoletin (cou- marins isolated from the aerial parts) exhibit antihepatotoxic, choleretic and cholagogue properties.The rhizomes contain dihydrofolia- menthin, loganin, menthiafolin and a triterpenoid saponin menyantho- side. Aqueous extract of the rhizome showed greater preserved renal function and higher glomerular filtration rate, possibly due to Platelet Activating Factor (PAF)-antagonistic effect of the extract.