A drug used to prevent migraine and cluster headaches. Methysergide is usually given only under hospital supervision, when other treatments have been ineffective.
Adverse effects of this drug can include dizziness, drowsiness, and nausea.
Long-term treatment may cause chest pain, kidney failure, or leg cramps.
A drug used to prevent attacks of MIGRAINE. The drug requires hospital supervision, as it has to be used with care because of the toxic effects it sometimes produces – for example, nausea, drowsiness and retroperitoneal FIBROSIS.
a variant of *migraine more common in men than in women (ratio 9:1). The unilateral pain around one eye is very severe and lasts between 15 minutes and 3 hours. The attacks commonly occur in the early hours of the morning but may occur up to eight times a day. The pain is associated with drooping of the eyelid (*ptosis), a bloodshot eye, a small pupil, and/or excessive production of tears in the eye. The acute treatment is with high-flow inhaled oxygen in conjunction with antimigraine drugs (5HT1 agonists) and prophylaxis is with such drugs as verapamil, lithium, or methysergide.... cluster headache
(RPF) a condition in which a dense plaque of fibrous tissue develops behind the peritoneum adjacent to the abdominal aorta. It may be secondary to malignancy, medication (methysergide, beta blockers), aortic aneurysm, or certain infections. The ureters become encased and hence obstructed, causing acute *anuria and renal failure. The obstruction can be relieved by *nephrostomy or the insertion of double J *stents. In the acute phase steroid administration may help, but in established RPF *ureterolysis is required.... retroperitoneal fibrosis
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