Metolazone Health Dictionary

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Metolazone: From 3 Different Sources

A diuretic drug used to treat hypertension. Metolazone is also given to reduce oedema in people with heart failure, kidney disorders, cirrhosis of the liver, or premenstrual syndrome. It is also used to treat certain types of kidney stone (see calculus, urinary tract). Adverse effects can include weakness, lethargy, and dizziness.
Health Source: BMA Medical Dictionary
Author: The British Medical Association
A thiazide-type diuretic (see THIAZIDES; DIURETICS) which is particularly e?ective when combined with a loop diuretic (see LOOP DIURETICS), when it produces profound diuresis. The drug is also useful for treating kidney stones (see under KIDNEYS, DISEASES OF).
Health Source: Medical Dictionary
Author: Health Dictionary
n. a *diuretic used to treat fluid retention (oedema) and high blood pressure. Side-effects include headache, loss of appetite, and digestive upsets, and blood potassium levels may be reduced.
Health Source: Oxford | Concise Colour Medical Dictionary
Author: Jonathan Law, Elizabeth Martin

Thiazides

Thiazides are a group of moderately potent DIURETICS which are e?ective when taken by mouth. They act by inhibiting the reabsorption of sodium and chloride in the renal tubules. They also have a blood-pressure-lowering e?ect. Chlorothiazide was the ?rst member of this group to be introduced. Their main use is to relieve OEDEMA in heart failure.

All thiazides are active by mouth with an onset of action within 1–2 hours, and a duration of 12–24 hours. Chlorthalidone is a thiazide-related compound that has a longer duration of action and only requires to be given on alternate days. The other thiazide drugs available include bendro?uazide, cyclopenthiazide, hydrochlorothiazide, hydro?umethiazide, indapamide, mefruside, methychlothiazide, metolazone, polythiazide and xipamide.... thiazides


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