Mitochondria have their own DNA. In human mitochondria, the is a double-helical circle that codes for 13 proteins. Mitochondria have a distinctive genetic code, and their genomes are not changed by meiosis during reproduction, making the useful in genetic studies.
The significance of mitochondria having their own is that diseases can be inherited via abnormalities of mitochondrial , and inheritance of the is maternal, directly from the egg.
Do Not Attempt Resuscitation order: an instruction, usually made by a patient while he or she has capacity and recorded in their notes, requesting that doctors desist from performing resuscitation in the event of physiological failure. By respecting a patient’s choice with regard to resuscitation, a doctor is respecting that patient’s *autonomy. If resuscitation is considered *futile, a decision not to attempt it may be taken; ideally, this should be communicated to the patient and the reasons explained sensitively.... dnar order
n. an enzyme that catalyses the cleavage of DNA. A genetically engineered form, recombinant human DNAse (dornase alfa), is used in the treatment of *cystic fibrosis to reduce the viscosity of the sticky secretions in the lungs. Administered by inhalation via a jet nebulizer, it appears to hydrolyse extracellular DNA that accumulates with other neutrophil debris in the airways. Trade name: Pulmozyme.... dnase
a group of inherited conditions transmitted through mitochondrial DNA (see mitochondrion), which can affect any organ and can present at any age. Most of these conditions are very rare; examples of those that are less rare include *Leigh syndrome, congenital *lactic acidosis, *MELAS, and Pearson syndrome.... mitochondrial disorders
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