Properly, infectious mononucleosis, a viral infection of the lymph pulp most frequently caused by the Epstein-Barr virus. The spleen, lymph nodes, and (sometimes) the liver are involved. The general symptoms are fever, sore throat, exhaustion, and abnormal white blood cells.
An acute viral infection in which the patient developes a sore throat, swollen lymph glands and fever. Also known as glandular fever, infectious mononucleosis is caused by members of the herpes group of viruses – the EPSTEIN BARR VIRUS and CYTOMEGALOVIRUS (CMV). The disease is more common among adolescents aged 15–17, an age when their immune defence mechanisms are not fully developed. In the UK many thousands of teenagers catch the disease every year, and kissing is believed to be the method of transmission among many of them. The blood contains many atypical lymphocytes (see LYMPHOCYTE) and the diagnosis is con?rmed with the heterophil antibodies test. Patients normally recover within six weeks without treatment, but they may feel tired and depressed for several months afterwards. Some cases of MYALGIC ENCEPHALOMYELITIS (ME) and other chronic fatigue syndromes occur after infection with this virus.
n. the condition in which the blood contains an abnormally high number of mononuclear leucocytes (*monocytes and *lymphocytes). See glandular fever.