Montelukast Health Dictionary

A group of naturally occurring, slow-reacting substances (SRSS) which have powerful smooth-muscle stimulating properties, particularly on bronchial smooth muscle. Leukotrienes are a metabolic derivative of PROSTAGLANDINS. Leukotriene receptor antagonists, such as montelukast and za?rlukast, are drugs useful in asthma.... leukotrienes

A group of antiallergy drugs, such as montelukast and zafirlukast, used to prevent symptoms of mild to moderate asthma. The drugs work by blocking the effects of leukotrienes – naturally occurring substances released in the lungs during an allergic reaction.

Because they are not bronchodilator drugs, and will not relieve an existing attack, they are usually used with bronchodilators and inhaled corticosteroids to reduce the frequency of attacks.

Side effects include gastrointestinal disturbances and headache.

Skin and hypersensitivity reactions may also occur.... leukotriene receptor antagonists

one of a class of drugs that prevent the action of *leukotrienes by blocking their receptors on cell membranes, such as those in the airways. These drugs are used in the management of asthma for their effects in relaxing the smooth muscle of the airways and in reducing inflammation in the bronchial linings. Examples are montelukast and zafirlukast; side-effects may include headache and abdominal pain or gastrointestinal upsets.... leukotriene receptor antagonist