Myelitis Health Dictionary

Paralysis, or PALSY, is loss of muscular power due to some disorder of the NERVOUS SYSTEM. Weakness – rather than total movement loss – is sometimes described as paresis. Paralysis may be temporary or permanent and may be accompanied by loss of feeling.

Paralysis due to brain disease The most common form is unilateral palsy, or HEMIPLEGIA, generally arising from cerebral HAEMORRHAGE, THROMBOSIS or EMBOLISM affecting the opposite side of the BRAIN. If all four limbs and trunk are affected, the paralysis is called quadraplegia; if both legs and part of the trunk are affected, it is called paraplegia. Paralysis may also be divided into ?accid (?oppy limbs) or spastic (rigid).

In hemiplegia the cause may be an abscess, haemorrhage, thrombosis or TUMOUR in the brain. CEREBRAL PALSY or ENCEPHALITIS are other possible causes. Sometimes damage occurs in the parts of the nervous system responsible for the ?ne control of muscle movements: the cerebellum and basal ganglion are such areas, and lack of DOPAMINE in the latter causes PARKINSONISM.

Damage or injury Damage to or pressure on the SPINAL CORD may paralyse muscles supplied by nerves below the site of damage. A fractured spine or pressure from a tumour may have this e?ect. Disorders affecting the cord which can cause paralysis include osteoarthritis of the cervical vertebrae (see BONE, DISORDERS OF), MULTIPLE SCLEROSIS (MS), MYELITIS, POLIOMYELITIS and MENINGITIS. Vitamin B12 de?ciency (see APPENDIX 5: VITAMINS) may also cause deterioration in the spinal cord (see also SPINE AND SPINAL CORD, DISEASES AND INJURIES OF).

Neuropathies are a group of disorders, some inherited, that damage the peripheral nerves, thus affecting their ability to conduct electrical impulses. This, in turn, causes muscle weakness or paralysis. Among the causes of neuropathies are cancers, DIABETES MELLITUS, liver disease, and the toxic consequences of some drugs or metals – lead being one example.

Disorders of the muscles themselves – for example, muscular dystrophy (see MUSCLES, DISORDERS OF – Myopathy) – can disturb their normal working and so cause partial or complete paralysis of the part(s) affected.

Treatment The aim of treatment should be to remedy the underlying cause – for example, surgical removal of a displaced intervertebral

disc or treating diabetes mellitus. Sometimes the cause cannot be recti?ed but, whether treatable or not, physiotherapy is essential to prevent joints from seizing up and to try to maintain some tone in muscles that may be only partly affected. With temporary paralysis, such as can occur after a STROKE, physiotherapy can retrain the sufferers to use their muscles and joints to ensure mobility during and after recovery. Patients with permanent hemiplegia, paraplegia or quadraplegia need highly skilled nursing care, rehabilitative support and resources, and expert help to allow them, if possible, to live at home.... paralysis

Surgical removal of part or all of a muscle. Myectomy may be performed to treat severely injured and infected muscles or to remove a fibroid in an operation called a myomectomy. myel- A prefix that denotes a relationship to bone marrow (as in multiple myeloma) or to the spinal cord (as in myelitis). The prefix myelo- has the same meaning.... myectomy

Inflammation of the vulva and vagina. Vulvovaginitis is often provoked as a result of the infections candidiasis or trichomoniasis. (See also vaginitis; vulvitis.)

walking Movement of the body by lifting the feet alternately and bringing 1 foot into contact with the ground before the other starts to leave it. A person’s gait is determined by body shape, size, and posture. The age at which children first walk varies enormously.

Walking is controlled by nerve signals from the brain’s motor cortex (see cerebrum), basal ganglia, and cerebellum that travel via the spinal cord to the muscles. Abnormal gait may be caused by joint stiffness, muscle weakness (sometimes due to conditions such as poliomyelitis or muscular dystrophy), or skeletal abnormalities (see, for example, talipes; hip, congenital dislocation of; scoliosis; bone tumour; arthritis). Children may develop knock-knee or bowleg; synovitis of the hip and Perthes’ disease are also common. Adolescents may develop a painful limp due to a slipped epiphysis (see femoral epiphysis, slipped) or to fracture or disease of the tibia, fibula or femur.

Abnormal gait may also be the result of neurological disorders such as stroke (commonly resulting in hemiplegia), parkinsonism, peripheral neuritis, multiple sclerosis, various forms of myelitis, and chorea.

Ménière’s disease may cause severe loss of balance and instability.... vulvovaginitis

n. inflammation of the brain and its membranous coverings (the meninges) caused by bacterial, viral, fungal, or amoebic infection. The disease may also involve the spinal cord, producing *myelitis with paralysis of both legs, sometimes called meningoencephalomyelitis.... meningoencephalitis

(Devic’s disease) a condition that resembles multiple sclerosis. The diagnosis is confirmed by the finding of the antiaquaparin-4 antibody (NMO IgG antibody). Typically there is a transverse *myelitis, producing paralysis and numbness of the legs and trunk below the inflamed spinal cord, and *retrobulbar (optic) neuritis affecting both optic nerves. The attacks of myelitis and optic neuritis may coincide or they may be separated by days or weeks. Recovery from the initial attack is often incomplete and severe relapses occur commonly unless treatment with immunosuppressive therapies is started.... neuromyelitis optica