An oxygen-carrying pigment that is present in muscles.
It consists of a combination of iron and protein.
Myoglobin stores oxygen, releasing it when it is needed by the muscles.
The presence of myoglobin in the urine is known as myoglobinuria.
Slight myoglobinuria may occur during prolonged exercise.
Severe myoglobinuria is usually caused by the release of myoglobin from a large area of damaged muscle, and may cause kidney failure.
The protein which gives MUSCLE its red colour. It has the property of combining loosely and reversibly with OXYGEN; this means that it is the vehicle whereby muscle extracts oxygen from the HAEMOGLOBIN in the blood circulating through it, and then releases the oxygen for use in muscle METABOLISM.
(myohaemoglobin) n. an iron-containing protein, resembling *haemoglobin, found in muscle cells. Like haemoglobin it contains a haem group, which binds reversibly with oxygen, and so acts as an oxygen reservoir within the muscle fibres.
The occurrence of MYOGLOBIN in the URINE. This is the oxygen-binding pigment in muscle and mild myoglobinuria may occur during exercise. Severe myoglobinuria will result from serious injuries, particularly crushing injuries, to muscles.... myoglobinuria
acute kidney injury caused by myoglobin that is released from damaged skeletal muscle (*rhabdomyolysis). This is usually the result of trauma and the condition was first recognized in victims trapped and crushed during the London Blitz. Muscle injury can also occur with pressure necrosis, particularly in the unconscious or immobile patient, or with a *compartment syndrome. Rarely it may complicate intensive muscular exercise or extensive viral myositis and it is a recognized complication of modest overexertion in some inherited disorders of muscle metabolism, such as *McArdle’s disease.... myoglobinuric acute renal failure
Health Encyclopedia